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https://www.readbyqxmd.com/read/28531919/bupleurum-chinense-extract-ameliorates-an-ova-induced-murine-allergic-asthma-through-the-reduction-of-the-th2-and-th17-cytokines-production-by-inactivation-of-nf%C3%AE%C2%BAb-pathway
#1
Thi Tho Bui, Chun Hua Piao, Chang Ho Song, Hee Soon Shin, Ok Hee Chai
Bupleurum chinense belongs to the Bupleurum spp. family that has been used in traditional herbal medicine for over thousand years. It has been reported to have anti-inflammatory, anti-oxidant, hepato-protective, antipyretic, analgesic, anti-fibrotic and immunomodulatory effect. However, the effect of B. Chinense on allergic asthma remains unclear. This study investigated the immunomodulatory effects of B. Chinense extracts (BCE) on airway inflammation in asthmatic mice model. In the ovalbumin (OVA)-induced allergic asthma model, we evaluated the number of total cells, differential inflammatory cells and the production of proinflammatory cytokines in bronchoalveolar lavage fluid (BALF) and lung homogenate as well as histological structure...
May 16, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28531826/how-many-familial-hypercholesterolemia-patients-are-eligible-for-pcsk9-inhibition
#2
Luis Masana, Nuria Plana, Sofia Pérez-Calahorra, Daiana Ibarretxe, Itziar Lamiquiz-Moneo, Juan Pedro-Botet, Manuel Suárez-Tembra, Pedro Valdivielso, Emilio Ortega, Fernando Civeira
BACKGROUND AND AIMS: Familial hypercholesterolemia (FH) is a high cardiovascular risk condition. Less than 20% of patients achieve the LDL targets. Although PCSK9 inhibitors improve control and reduce cardiovascular events, official recommendations for their use are restrictive. We aim to assess the number of FH patients suitable for PCSK9 inhibition according to the European guidelines. METHODS: A total of 2685 FH patients, with a minimum follow-up of 6 months, included in the Dyslipidemia Registry of the Spanish Arteriosclerosis Society, were sorted according to the intensity of their lipid-lowering therapy (LLT) and LDL cholesterol levels achieved...
May 12, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28531244/awareness-prevalence-treatment-and-control-of-hypertension-in-western-nepal
#3
Dinesh Neupane, Archana Shrestha, Shiva Raj Mishra, Joakim Bloch, Bo Christensen, Craig S McLachlan, Arjun Karki, Per Kallestrup
BACKGROUND: Hypertension is a significant contributor to cardiovascular and renal diseases. In low-income settings like Nepal, there are few epidemiological studies assessing hypertension burden. Thus, the purpose was to determine prevalence, awareness, treatment, and control of hypertension in Nepal. METHODS: A cross-sectional survey was conducted in semi-urban area of western Nepal among randomly selected participants, aged between 25 and 65 years. Systolic blood pressure (BP) ≥140 mm Hg and/or diastolic BP of ≥90 mm Hg and/or taking current antihypertensive medicine defined as hypertension...
May 22, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28530338/-bibliotherapy-as-a-clinical-tool-and-its-applications-in-diagnosis-treatment-and-teaching-medicine
#4
REVIEW
Iris Shoshani Helvitz
Bibliotherapy, the practice of healing through stories, is described throughout this article. Case reports show how stories can be used as both a diagnostic tool and a treatment option. Family physicians use bibliotherapy in an all-inclusive manner to heal, consolidate and deepen patient-doctor relationships, help heal the healers and teach medicine. Stories are clinical tools that connect the patients' world with that of their doctors. Stories are a simple tool that don't require great skill and can enhance any patient or physician's experience...
December 2016: Harefuah
https://www.readbyqxmd.com/read/28530309/-monitoring-units-in-departments-of-internal-medicine-frequency-impact-and-satisfaction
#5
David Raveh-Brawer, Tanya Itzekson, Ruth Henshke-Bar-Meir, Noa Sylvetsky, Reuven Friedmann, Ranana Siegman, Tanya Mor, Moshe Hersch, Amos M Yinnon, Shoshana Zevin
BACKGROUND: Due to increasing numbers of elderly, seriously ill patients and shortage of ICU beds, many hospitals have established monitoring units (MU) in their medical departments. OBJECTIVES: (1) To assess the national prevalence of MUs in medical departments; (2) to determine the outcome of consecutively admitted MU patients; (3) to evaluate patient/ family satisfaction with care. METHODS: The case control study included all 123 patients hospitalized in the MU during a 5-month period, compared with two control groups: (1) 123 patients admitted to medical departments, matched at a ratio of 1:1 by gender, age±10 years and mechanical ventilation; (2) all 52 medical patients treated in the ICU...
January 2017: Harefuah
https://www.readbyqxmd.com/read/28529233/the-medicinal-rod-slave-health-and-redhibition-law-in-george-washington-cable-s-i-the-grandissimes-i
#6
Heather Chacón
The economic transactions and litigation necessary for slavery to function, coupled with the South's honor culture, meant skepticism and posturing frequently attended the buying and selling of enslaved people. This atmosphere provided opportunities for enslaved individuals familiar with the symbiotic ways their health and value intertwined to manipulate owners by feigning illness or adopting behaviors contrary to those of a "sound and sane" captive under Louisiana's redhibitory (slave warranty) law. Such actions offered a chance at preserving that which slavery denied its victims: proximity to family, a reduced chance of being sold, and an opportunity to exert agency within a strictly oppressive system...
2017: Literature and Medicine
https://www.readbyqxmd.com/read/28527637/the-state-of-shared-decision-making-in-malaysia
#7
Yew Kong Lee, Chirk Jenn Ng
Shared decision making (SDM) activities in Malaysia began around 2010. Although the concept is not widespread, there are opportunities to implement SDM in both the public and private healthcare sectors. Malaysia has a multicultural society and cultural components (such as language differences, medical paternalism, strong family involvement, religious beliefs and complementary medicine) influence medical decision making. In terms of policy, the Ministry of Health has increasingly mentioned patient-centered care as a component of healthcare delivery while the Malaysian Medical Council's guidelines on doctors' duties mentioned collaborative partnerships as a goal of doctor-patient relationships...
May 17, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28526512/privacy-trainee-rights-and-accountability-in-radiology-education
#8
REVIEW
Cory M Pfeifer
RATIONALE AND OBJECTIVES: Academic radiologists commonly hold multiple simultaneous roles within the landscape of physician training. This paper analyzes theoretical scenarios describing relationships between medical students, residents, and physician educators in radiology. MATERIALS AND METHODS: The scenarios presented involve medical student supervision, radiology resident recruitment, and resident termination with respect to relevant ethical, regulatory, and legal considerations...
March 28, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28526020/salmonella-serotypes-and-their-antimicrobial-susceptibility-in-apparently-healthy-dogs-in-addis-ababa-ethiopia
#9
Bitsu Kiflu, Haile Alemayehu, Mukarim Abdurahaman, Yohannes Negash, Tadesse Eguale
BACKGROUND: The close bond between pet animals and family members poses risk of infection with zoonotic bacterial pathogens such as Salmonella. No data is available on occurrence of Salmonella in dogs in Ethiopia. The aim of this study was therefore to determine the prevalence, serotype distribution and antimicrobial resistance of Salmonella from feces of apparently healthy dogs in Addis Ababa, Ethiopia. RESULTS: Of the total 360 dogs examined, 42 (11.7%; 95% Confidence limit of 8...
May 19, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28525368/indirubin-improves-antioxidant-and-anti-inflammatory-functions-in-lipopolysaccharide-challenged-mice
#10
Tianjie Qi, Haitao Li, Shuai Li
Indirubin, a traditional Chinese medicine formulation from the Muricidae family, has been reported to exhibit abroad anti-cancer and anti-inflammation activities and mediate nuclear factor-κB (NF-κB) signal. Thus, this study aimed to investigate the protective effects of indirubin on LPS-induced acute lung injury and the potential mechanism in mice. The results showed that LPS treatment caused oxidative stress and inflammation in mice. Indirubin alleviated LPS-caused oxidative stress and inflammation via reducing MDA abundance and IL-1β and TNF-α expressions in mice...
May 2, 2017: Oncotarget
https://www.readbyqxmd.com/read/28521577/developing-family-medicine-in-ethiopia
#11
Naheed A Lakhani, Oguchi Nwosu
No abstract text is available yet for this article.
May 18, 2017: Education for Primary Care
https://www.readbyqxmd.com/read/28521336/chemical-ecology-of-antibiotic-production-by-actinomycetes
#12
Anne van der Meij, Sarah F Worsley, Matthew I Hutchings, Gilles P van Wezel
Actinomycetes are a diverse family of filamentous bacteria that produce a plethora of natural products relevant for agriculture, biotechnology and medicine, including the majority of the antibiotics we use in the clinic. Rather than as free-living bacteria, many actinomycetes have evolved to live in symbiosis with among others plants, fungi, insects and sponges. As a common theme, these organisms profit from the natural products and enzymes produced by the actinomycetes, for example, for protection against pathogenic microbes, for growth promotion or for the degradation of complex natural polymers such as lignocellulose...
May 1, 2017: FEMS Microbiology Reviews
https://www.readbyqxmd.com/read/28517990/risk-and-benefit-in-personalised-medicine-an-end-user-view
#13
Alastair Kent
Personalised, or stratified, medicine is creating opportunities for the development of targeted therapies for many hitherto unmet clinical needs. For patients and families this is a cause for optimism. But it is unlikely that these novel therapies will provide complete cures. Rather they will address some but not all symptoms of a condition. In such circumstances, early engagement with patients and families will ensure that developments are targeted at those aspects of a condition which really matter, not just those that are easy to count...
April 2017: New Bioethics: a Multidisciplinary Journal of Biotechnology and the Body
https://www.readbyqxmd.com/read/28516798/complementary-and-alternative-medicine-use-in-uninsured-children-in-texas
#14
Sanghamitra M Misra, Danielle Guffey, Isabel Roth, Angelo P Giardino
Use of complementary and alternative medicine (CAM) among US children is 12% according to the 2012 National Health Interview Study. Certain pediatric populations have higher CAM use. We studied an uninsured population because limited access to care likely results in higher CAM use. We surveyed 250 uninsured patients in a free pediatric mobile clinic program. In the largely Hispanic population, rate of CAM use in the preceding 12 months was 45% among children and 59% among parents. Ninety-one percent of children who used CAM had parents who used CAM while only 32% of parents used CAM for themselves but did not use CAM for their children ( P < ...
May 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28516087/dna-sequence-analysis-in-clinical-medicine-proceeding-cautiously
#15
REVIEW
Moyra Smith
Delineation of underlying genomic and genetic factors in a specific disease may be valuable in establishing a definitive diagnosis and may guide patient management and counseling. In addition, genetic information may be useful in identification of at risk family members. Gene mapping and initial genome sequencing data enabled the development of microarrays to analyze genomic variants. The goal of this review is to consider different generations of sequencing techniques and their application to exome sequencing and whole genome sequencing and their clinical applications...
2017: Frontiers in Molecular Biosciences
https://www.readbyqxmd.com/read/28514873/unpacking-community-mobility-a-preliminary-study-into-the-embodied-experiences-of-stroke-survivors
#16
Christa S Nanninga, Louise Meijering, Klaas Postema, Marleen C Schönherr, Ant T Lettinga
PURPOSE: To enrich the discussion on mobility in stroke rehabilitation by translating theoretical repertoires of mobility from the context of geography to rehabilitation. METHOD: Qualitative research methodology was applied, and included in-depth interviews with stroke survivors. RESULTS: This study revealed: (a) social and material differences in clinical, private and public places; (b) ambivalences and shifting tensions in bodily, family and community life; (c) differences in access to resources to be used for mobility...
May 17, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28514600/evaluating-five-different-loci-rbcl-rpob-rpoc1-matk-and-its-for-dna-barcoding-of-indian-orchids
#17
Iffat Parveen, Hemant Kumar Singh, Saloni Malik, Saurabh Raghuvanshi, Shashi Bhushan Babbar
Orchidaceae, one of the largest families of angiosperms, is represented in India by 1600 species distributed in diverse habitats. Orchids are in high demand due to their beautiful flowers and therapeutic properties. Overexploitation and habitat destruction have made many orchid species endangered. In the absence of effective identification methods, illicit trade of orchids continues unabated. Considering DNA barcoding as a potential identification tool, species discrimination capability of five loci, ITS matK, rbcL, rpoB and rpoC1, was tested in 393 accessions of 94 Indian orchid species belonging to 47 genera, including one listed in Appendix I of CITES and 26 medicinal species...
May 17, 2017: Genome Génome / Conseil National de Recherches Canada
https://www.readbyqxmd.com/read/28513519/attitude-and-knowledge-of-family-medicine-practitioners-towards-the-association-between-periodontal-disease-and-obesity
#18
Z Akram, T Abduljabbar, A Hanif, A Khan, F Vohra
OBJECTIVES: To assess the attitude and knowledge of family medicine practitioners (FMPs) towards the association between periodontal disease and obesity. MATERIALS AND METHODS: A cross-sectional study was performed and a 13-item survey questionnaire was given to FMPs practicing in 12 different teaching hospitals in Karachi, Pakistan. The questions were aimed at exploring the knowledge of FMP's regarding the association of obesity and periodontal disease and their attitude towards the association of obesity and periodontal disease...
May 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28512988/phytochemistry-and-pharmacology-of-phyllanthus-niruri-l-a-review
#19
REVIEW
Navneet Kaur, Baljinder Kaur, Geetika Sirhindi
Phyllanthus niruri, a typical member of family Euphorbiaceae, is a small annual herb found throughout the tropical and subtropical regions of both hemispheres. The genus Phyllanthus has been used in traditional medicine for its wide range of pharmacological activities like antimicrobial, antioxidant, anticancer, antiinflammatory, antiplasmodial, antiviral, diuretic and hepatoprotective. This review summarizes the information about morphological, biochemical, ethanobotanical, pharmacological, biological and toxicological activities with special emphasis on mechanism of anticancer activity of P...
May 17, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28512604/traditional-dentistry-knowledge-among-serbs-in-several-balkan-countries
#20
Dragan V Ilic, Biljana Andjelski Radicevic, Anely Nedelcheva, Ivana Djurovic, Dejan Ostojic
BACKGROUND/AIM: There are still unrevealed treasures of traditional dental medicine, that is, the reason to investigate and present various ways in treatment of oral and orofacial tissues, as well as magic and religious elements involved in representative areas among Serbs. MATERIALS AND METHODS: Information was collected from the elderly non-professional folk dentists and herbalists with the additional help of local physicians and dentists that was done through questionnaire and personal interviews...
April 2017: Journal of Intercultural Ethnopharmacology
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