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Diabetic Vitrectomy

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https://www.readbyqxmd.com/read/29752593/effects-of-kallidinogenase-in-patients-undergoing-vitrectomy-for-diabetic-macular-edema
#1
Yuki Yoshizumi, Zaigen Ohara, Hitoshi Tabuchi, Hitomi Sumino, Yukiko Maeda, Hideki Mochizuki, Ken Yamane, Yoshiaki Kiuchi
PURPOSE: To evaluate the effectiveness of the combination of vitrectomy with kallidinogenase for diabetic macular edema (DME). METHODS: This study was designed as a prospective, randomized, multicenter study comparing 19 eyes of 19 patients who received 150 units of kallidinogenase administered a day for 52 weeks from the day after vitrectomy (study group) with 20 eyes of 20 patients who received no kallidinogenase (control group). The main outcome measurements included logMAR visual acuity and central foveal thickness (CFT) before surgery and at 3, 6, 9, and 12 months after vitrectomy...
May 12, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29752167/dipeptidyl-peptidase-4-inhibitor-use-and-risk-of-diabetic-retinopathy-a-population-based-study
#2
N H Kim, J Choi, N H Kim, K M Choi, S H Baik, J Lee, S G Kim
AIMS: This study examined whether dipeptidyl peptidase (DPP)-4 inhibitor use is beneficial or harmful to diabetic retinopathy (DR) compared with other glucose-lowering agents in patients with type 2 diabetes (T2D). METHODS: From a population-based cohort provided by the National Health Insurance Service in Korea, 67,743 adults with T2D were identified as having been treated with oral glucose-lowering agents between 2008 and 2013. Matching (1:1) was performed for two groups comparing ever-use (cases) and never-use (controls) of DPP-4 inhibitors (n=14,522 in each group)...
March 27, 2018: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29746442/community-associated-methicillin-resistant-staphylococcus-aureus-subretinal-abscess-in-a-nonbacteremic-patient-treated-with-internal-drainage-and-retinectomy
#3
Jessica F Yang, Kamal Kishore
PURPOSE: To report a case of community-associated methicillin-resistant Staphylococcus aureus subretinal abscess that continued to progress, despite intravitreal and systemic antibiotic therapy. METHODS: Retrospective chart review of a 77-year-old female patient with well-controlled diabetes mellitus who developed a left eye endophthalmitis and subretinal abscess from methicillin-resistant S. aureus colonization in the absence of any systemic focus of infection...
May 9, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29719650/intraocular-lens-calcification-clinico-pathological-report-of-two-cases-and-literature-review
#4
Mansour Rahimi, Ali Azimi, Masoud Hosseinzadeh
Purpose: We report the clinicopathological features and surgical outcomes of two cases of intraocular lens (IOL) calcification along with a review of the current literature. Case Report: The first patient was a 53-year-old woman with diabetes mellitus (type 2) who underwent phacoemulsification with posterior chamber IOL insertion (PCIOL), and pars plana vitrectomy. Significant clouding of the IOL was first noted after 1.5 years, and the IOL was replaced with an Artisan lens...
April 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29713141/risk-factors-for-requirement-of-filtration-surgery-after-vitrectomy-in-patients-with-proliferative-diabetic-retinopathy
#5
Masashi Sakamoto, Ryuya Hashimoto, Izumi Yoshida, Takatoshi Maeno
Purpose: We retrospectively reviewed patients with postoperative neovascular glaucoma (NVG) after vitrectomy for proliferative diabetic retinopathy to investigate how variables assessed before, during, and after vitrectomy are associated with the requirement for filtration surgery. Patients and methods: The subjects in this retrospective, observational, comparative study were 55 consecutive patients (61 eyes) who underwent vitrectomy for proliferative diabetic retinopathy at Toho University Sakura Medical Center between December 2011 and November 2016, were followed up for at least 6 months after surgery, and developed NVG within 2 years after surgery...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29675350/postoperative-intraocular-lens-opacification
#6
Shang-Te Ma, Chung-May Yang, Yu-Chih Hou
Intraocular lens (IOL) opacification is rare but may occur after non-Descemet stripping automated endothelial keratoplasty (n-DSAEK) or intravitreal air injection after pars plana vitrectomy (PPV). We reported two cases of IOL opacification within the pupillary region. Chart was retrospectively reviewed. The predisposing factors and the visual acuity were analyzed. The opacification was evaluated by anterior segment optical coherence tomography (AS-OCT). A 68-year-old healthy woman with pseudophakic bullous keratopathy underwent uneventful n-DSAEK in the right eye...
January 2018: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29670325/retinal-detachment-in-albinism
#7
Ahmad M Mansour, Jay Chhablani, J Fernando Arevalo, Lihteh Wu, Ravi Sharma, Suthasinee Sinawat, Tharikarn Sujirakul, Alexandre Assi, Wandsy M Vélez-Vázquez, Mohamad A Mansour, Ozcan Kayikcioglu, Cem Kucukerdonmez, Ali Kal
Purpose: To report the visual and anatomic outcomes of albino retinal detachment (ARD) repair. Methods: Collaborative retrospective analysis of ARD. Outcome measures were number of surgical interventions, final retinal reattachment, and best corrected visual acuity (BCVA) at last follow-up. Results: Seventeen eyes of 16 patients (12 males; mean age =37.8 years) had the following complications at presentation: macula off (14), total (7) or inferior detachment (5), proliferative vitreoretinopathy (5), detectable break (16), lattice (5), horseshoe tears (9), and giant tear or dialysis (4)...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29668525/primary-core-vitrectomy-technique-before-cataract-surgery-in-combined-phacovitrectomy-for-eyes-with-dense-vitreous-hemorrhages
#8
Kyung Sup Shin, Hyung Bin Lim, Yong Il Shin, Seong Eun Lee, Young Joon Jo, Jung Yeul Kim
PURPOSE: To investigate the efficacy and safety of a primary core vitrectomy technique for combined phacovitrectomy in eyes showing a poor red reflex because of dense vitreous hemorrhage before cataract surgery. METHODS: A total of 156 eyes from 156 patients, who underwent combined phacovitrectomy because of cataract and dense vitreous hemorrhage, and who were followed up for at least 6 months were included. The patients were divided into a primary phacoemulsification group (Group A, 80 eyes) who underwent phacoemulsification first followed by total vitrectomy and a primary vitrectomy group (Group B, 76 eyes) who underwent core vitrectomy first followed by cataract surgery and followed by total vitrectomy...
April 17, 2018: Retina
https://www.readbyqxmd.com/read/29643911/pars-plana-vitrectomy-in-vitreous-hemorrhage-with-or-without-intravitreal-bevacizumab-a-comparative-overview
#9
Syed Muhammad Faisal, Muhammad Ali Tahir, Alyscia Miriam Cheema, Muhammad Ijaz Anjum
Objective: To compare the success in patients having vitreous hemorrhage undergoing pars plana vitrectomy with or without preoperative intravitreal injection of Bevacizumab. Methods: This Randomized controlled trial was conducted at Department of Ophthalmology, Jinnah Postgraduate Medical Centre. Karachi. Duration of study was six months from January 2010 to June 2010. In this study 56 patients of advanced diabetic eye disease were divided into two groups. Patients in Group-A underwent three ports pars plana vitrectomy with preoperative intravitreal injection of Bevacizumab (Avastin) 1...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29606379/cost-evaluation-of-early-vitrectomy-versus-panretinal-photocoagulation-and-intravitreal-ranibizumab-for-proliferative-diabetic-retinopathy
#10
James Lin, Jonathan S Chang, Nicolas A Yannuzzi, William E Smiddy
PURPOSE: To evaluate costs and cost-utility of early vitrectomy (pars plana vitrectomy [PPV]) compared with panretinal photocoagulation (PRP) and intravitreal ranibizumab (IVR) for proliferative diabetic retinopathy (PDR) without diabetic macular edema. DESIGN: A decision analysis model of cost-utility. PARTICIPANTS: There were no participants. METHODS: A decision analysis was based on results from the Diabetic Retinopathy Clinical Research Network Protocol S comparing treatment of PRP with IVR (0...
March 29, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29600174/outcomes-of-transconjunctival-sutureless-27-gauge-vitrectomy-for-vitreoretinal-diseases
#11
Jie Li, San-Mei Liu, Wen-Tao Dong, Fang Li, Cai-Hong Zhou, Xiao-Dan Xu, Jie Zhong
AIM: To evaluate the safety and efficacy profile of 27-gauge (27G) pars plana vitrectomy (PPV) for the treatment of various vitreoretinal diseases. METHODS: The clinical outcomes of 61 eyes (58 patients) with various vitreoretinal diseases following 27G PPV were retrospectively reviewed. RESULTS: Surgical indications included rhegmatogenous retinal detachment ( n =24), full-thickness macular hole ( n =12), diabetic retinopathy ( n =11), vitreous hemorrhage ( n =6), Eales disease ( n =4), pathological myopia-related vitreous floater ( n =2), and macular epiretinal membrane ( n =2)...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29589220/ocular-involvement-in-melioidosis-a-23-year-retrospective-review
#12
Sasi Yaisawang, Somkiat Asawaphureekorn, Ploenchan Chetchotisakd, Surasakdi Wongratanacheewin, Peerapat Pakdee
BACKGROUND: Ocular involvement in melioidosis is rare and has devastating outcomes. Although there have been few reports on the condition, Khon Kaen, a city in northeast Thailand, has been called the "capital of melioidosis" due to the high prevalence of the condition in the region. We retrospectively reviewed all admitted cases of melioidosis with ocular involvement from the two largest hospitals in Khon Kaen. We reviewed cases from Srinagarind Hospital (a university hospital) of patients admitted between 1993 and 2016 and from Khon Kaen Hospital (a provincial hospital) of patients who presented from 2012 to 2016...
March 27, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29584759/anti-inflammatory-cytokine-and-angiogenic-factors-levels-in-vitreous-samples-of-diabetic-retinopathy-patients
#13
Teresa Tsai, Sandra Kuehn, Nikolaos Tsiampalis, Minh-Khoa Vu, Vinodh Kakkassery, Gesa Stute, H Burkhard Dick, Stephanie C Joachim
Evaluation of cytokines in patients with diabetic retinopathy (DR) is important for the identification of future additive or alternative treatment options. Therefore, vitreous samples were obtained from patients with DR and patients with macular hole or macular pucker (control group) during 23-gauge-vitrectomy (n = 17/group). The levels of three pro-inflammatory (IL-1ß, IL-6, IFN-γ) and pleiotropic cytokines (IL-2, IL-4, IL-13) as well as VEGF, VEGF-A, and PGF were measured using an enzyme linked immunosorbent assay (ELISA)...
2018: PloS One
https://www.readbyqxmd.com/read/29582819/vitreous-rebleed-following-sutureless-vitrectomy-incidence-and-risk-factors
#14
Prabhushanker Mahalingam, Tasneem Tameem Topiwalla, Geetha Ganesan
Purpose: This study aims to evaluate the incidence and risk factors for vitreous rebleed (VRB) following 25-gauge sutureless vitrectomy for vitreous hemorrhage (VH) in diabetic retinopathy. Methods: A retrospective review of 190 diabetic patients having undergone vitrectomy for VH at a tertiary eye care center was analyzed. Demographic data of patients along with risk factors such as blood sugar levels (BSL), blood pressure (BP), anticoagulant use, and pan-retinal photocoagulation status (PRP) were tabulated...
April 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29582816/prevalence-progression-and-outcomes-of-diabetic-retinopathy-during-pregnancy-in-indian-scenario
#15
Tarjani Makwana, Brijesh Takkar, Pradeep Venkatesh, Jai Bhagwan Sharma, Yashdeep Gupta, Rohan Chawla, Rajpal Vohra, Alka Kriplani, Nikhil Tandon
Purpose: The objective of this study is to evaluate pattern of diabetic retinopathy (DR) during pregnancy in females with pregestational diabetes mellitus (DM). Methods: This is an ambispective observational cohort study conducted at an Indian tertiary care centre. A total of 50 pregnant females with pregestational DM were included while those with gestational DM were excluded from the study. Ocular examination (inclusive of fundus photography) was conducted and systemic parameters (inclusive of Glycated hemoglobin) were assessed during each of the 3 trimesters and 3 months postpartum...
April 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29564551/preexisting-epiretinal-membrane-is-associated-with-pseudophakic-cystoid-macular-edema
#16
Friederike Schaub, Werner Adler, Philip Enders, Meike C Koenig, Konrad R Koch, Claus Cursiefen, Bernd Kirchhof, Ludwig M Heindl
PURPOSE: The purpose of the present study was to evaluate whether preexisting epiretinal membrane (ERM) is a significant risk factor for developing pseudophakic cystoid macular edema (PCME). METHODS: Two hundred four consecutive eyes and 153 consecutive eyes without preexisting epiretinal membranes were retrospectively compared regarding PCME development following phacoemulsification with posterior chamber lens implantation. Patients with vascular retinal diseases, uveitis, trauma, neovascular macular degeneration, chronic inflammatory conditions, diabetic retinopathy, endophthalmitis, eventful cataract surgery, and combination of cataract surgery and vitrectomy during the observation period were excluded...
May 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29543201/-effect-of-internal-limiting-membrane-peeling-on-morpho-functional-state-of-the-retina-in-patients-with-proliferative-diabetic-retinopathy-preliminary-report
#17
M M Bikbov, R R Fayzrakhmanov, M R Kalanov
PURPOSE: To compare morpho-functional parameters of retina during vitrectomy with and without internal limiting membrane (ILM) peeling in patients with proliferative diabetic retinopathy. MATERIAL AND METHODS: The study included 55 patients (55 eyes) that had underwent vitreoretinal surgery in the setting of antivasoproliferative therapy for proliferative diabetic retinopathy. Patients of the 1st group (n=27) underwent vitrectomy with silicone tamponade, 2nd group (n=28) received similar treatment with the addition of ILM peeling...
2018: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29533244/thin-rigid-contact-lens-used-in-vitreous-retinal-surgery-for-corneal-protection-a-randomized-controlled-trial
#18
Zizhong Hu, Yuzhi Ding, Xinhua Zheng, Songtao Yuan, Jia Li, Ping Xie, Qinghuai Liu
PURPOSE: To design a rigid contact lens (CL) to be used in combination with a wide-angle viewing system and analyze its protection for corneal epithelial during vitreous-retinal surgery. METHODS: A thin and lightweight rigid CL was designed and constructed. The impact of the CL on the visualized fundus range was evaluated using a concrete eye model. Patients with severe proliferative diabetic retinopathy (PDR) were randomized to either the CL group, corneal protective agent (CPA) group, or balanced salt solution (BSS) group...
March 12, 2018: Eye & Contact Lens
https://www.readbyqxmd.com/read/29516045/anatomical-results-and-complications-after-silicone-oil-removal
#19
Daniel Constantin Brănişteanu, Andreea Moraru, Andrei Bîlha
The aim of the report was to evaluate anatomical results and intra and postoperative complications after silicone oil (SIO) removal. Methods: Retrospective, interventional study evaluating consecutive cases with ambulatory SIO removal after vitrectomy for complex retinal detachments. The anatomical result was the main followed parameter. Intra and postoperative complications and also intraocular pressure changes were evaluated. Cases were followed-up for at least 12 months. Results: A total of 98 consecutive cases were reviewed...
October 2017: Romanian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29507304/observation-of-optic-disc-neovascularization-using-oct-angiography-in-proliferative-diabetic-retinopathy-after-intravitreal-conbercept-injections
#20
Xiao Zhang, Chan Wu, Li-Jia Zhou, Rong-Ping Dai
This study reports the short-term efficacy and safety of intravitreal conbercept injections for neovascularization at the disc (NVD) in patients with proliferative diabetic retinopathy (PDR). Conbercept is a recombinant fusion protein with a high affinity for all isoforms of vascular endothelial growth factor (VEGF)-A, placental growth factor and VEGF-B. A prospective case series study was conducted in 15 patients (15 eyes). Patients had complete ocular examinations and received a 0.5 mg intravitreal conbercept injection followed by supplemental pan-retinal photocoagulation (PRP)...
March 5, 2018: Scientific Reports
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