keyword
https://read.qxmd.com/read/38547388/physiological-factors-associated-with-unsatisfied-inspiration-at-peak-exercise-in-healthy-adults
#1
JOURNAL ARTICLE
Olivia N Ferguson, Reid A Mitchell, Michele R Schaeffer, Andrew H Ramsook, Kyle G P J M Boyle, Satvir S Dhillon, Julia Zhang, Alanna S Hind, Dennis Jensen, Jordan A Guenette
INTRODUCTION: Contrary to common belief, a growing body of evidence suggests that unsatisfied inspiration (UI), an inherently uncomfortable quality of dyspnea, is experienced by ostensibly healthy adults during high-intensity exercise. Based on our understanding of the mechanisms of UI among people with chronic respiratory conditions, this analysis tested the hypothesis that the experience of UI at peak exercise in young, healthy adults reflects the combination of high ventilatory demand and critical inspiratory constraints...
March 28, 2024: Medicine and Science in Sports and Exercise
https://read.qxmd.com/read/38547096/a-new-automatic-sugarcane-seed-cutting-machine-based-on-internet-of-things-technology-and-rgb-color-sensor
#2
JOURNAL ARTICLE
Liu Yang, Loai S Nasrat, Mohamed E Badawy, Daniel Eutyche Mbadjoun Wapet, Manar A Ourapi, Tamer M El-Messery, Irina Aleksandrova, Mohamed Metwally Mahmoud, Mahmoud M Hussein, Abdallah E Elwakeel
Egypt is among the world's largest producers of sugarcane. This crop is of great economic importance in the country, as it serves as a primary source of sugar, a vital strategic material. The pre-cutting planting mode is the most used technique for cultivating sugarcane in Egypt. However, this method is plagued by several issues that adversely affect the quality of the crop. A proposed solution to these problems is the implementation of a sugarcane-seed-cutting device, which incorporates automatic identification technology for optimal efficiency...
2024: PloS One
https://read.qxmd.com/read/38545888/safety-and-efficacy-of-a-reduced-frequency-viral-monitoring-strategy-for-epstein-barr-virus-cytomegalovirus-and-bk-polyomavirus-post-kidney-transplant-a-quality-assurance-initiative
#3
JOURNAL ARTICLE
Christie Rampersad, William Kong, Chris Wiebe, Robert Balshaw, Jared Bullard, Armelle Perez Cortes Villalobos, Aaron Trachtenberg, James Shaw, Martin Karpinski, Peter W Nickerson, Julie Ho
BACKGROUND: There is variability in recommended viral monitoring protocols after kidney transplant. In response to increased demand for laboratory testing during the COVID-19 pandemic, the Transplant Manitoba Adult Kidney Program updated its monitoring protocols for cytomegalovirus (CMV), Epstein-Barr virus (EBV), and BK polyomavirus (BKV) to a reduced frequency. METHODS: This single-center nested case-control study evaluated 252 adult kidney transplant recipients transplanted from 2015 to 2021, with the updated protocols effective on March 19th 2020...
April 2024: Clinical Transplantation
https://read.qxmd.com/read/38544885/therapeutic-responses-to-efgartigimod-for-generalized-myasthenia-gravis-in-japan
#4
JOURNAL ARTICLE
Shigeaki Suzuki, Akiyuki Uzawa, Yuriko Nagane, Masayuki Masuda, Shingo Konno, Tomoya Kubota, Makoto Samukawa, Kei Ishizuchi, Daiki Tokuyasu, Hideo Handa, Manato Yasuda, Naoki Kawaguchi, Takashi Kimura, Yasushi Suzuki, Takamichi Sugimoto, Naoya Minami, Masanori P Takahashi, Hiroyuki Murai, Kimiaki Utsugisawa
BACKGROUND AND OBJECTIVES: Efgartigimod, which has been well tolerated and efficacious in individuals with generalized myasthenia gravis (MG), is available in Japan not only for the treatment of anti-acetylcholine receptor-positive (AChR+) but also anti-muscle-specific receptor tyrosine kinase (MuSK+) and seronegative generalized MG. We report details of the use of efgartigimod for generalized MG in clinical practice in Japan. METHODS: We included patients with generalized MG in the 2021 survey of Japan Myasthenia Gravis Registry (JAMG-R) study group who received an initial cycle of efgartigimod between May and September 2022...
June 2024: Neurology. Clinical Practice
https://read.qxmd.com/read/38544559/associations-of-recurrent-lumbar-disc-herniation-after-percutaneous-endoscopic-lumbar-discectomy-with-age-body-mass-index-modic-change-disc-degeneration-and-sacral-slope-a-quantitative-review
#5
JOURNAL ARTICLE
Jinlong Zhao, Lingfeng Zeng, Shuai Zhao, Guihong Liang, Bangxin Sha, Haoyang Fu, Weiyi Yang, Jun Liu, Yuping Zeng
Recurrent lumbar disc herniation (rLDH) seriously affects the quality of life of patients and increases the medical burden. The purpose of the present study was to determine the risk factors for rLDH after percutaneous endoscopic lumbar discectomy (PELD). The PubMed, Cochrane Library and Embase databases were searched for studies on the factors associated with rLDH after PELD. The databases were searched from inception to March 30, 2023. The combined effects of categorical variables and continuous variables were measured using odds ratios (ORs) and weighted mean differences (WMDs), respectively, and their corresponding 95% confidence intervals (CIs) were calculated...
May 2024: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/38542957/a-laboratory-experimental-study-on-enhancing-the-oil-recovery-mechanisms-of-polymeric-surfactants
#6
JOURNAL ARTICLE
Junhui Guo, Fulin Wang, Yunfei Zhao, Peng Wang, Tianzhi Wang, Jixiang Yang, Bo Yang, Liangliang Ma
In order to evaluate the physical and chemical properties of polymer surfactants and analyze their oil displacement mechanisms, three types of poly-surfactant used in the Daqing oil field were chosen to be researched, and the oil displacement effects were studied using poly-surfactants of different viscosity, dehydrating rate, and core permeability. The main purpose is to determine the reasonable range of different characteristic indexes of polymeric surfactant flooding. The oil displacement effect of 15 cores was analyzed, and the effects of viscosity, the dehydrating rate of emulsion, and permeability on EOR (Enhanced Oil Recovery) were analyzed...
March 15, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38542494/assessment-of-blood-and-semen-detection-and-dna-collection-from-swabs-up-to-three-months-after-deposition-on-five-different-cloth-materials
#7
JOURNAL ARTICLE
Francisco Medina-Paz, Brandon Kuba, Emily Kryvorutsky, Gabriela Roca, Sara C Zapico
Body fluid identification plays a crucial role in criminal investigations. Because of their presence in many cases, blood and semen are the most relevant body fluids in forensic sciences. Based on antigen-antibody reactions binding unique proteins for each body fluid, serological assays represent one of the most rapid and highly specific tests for blood and semen. Currently, few studies have assessed the factors affecting body fluid identification by applying these assays. This work aimed to study the effect of different fabrics from clothes and time since deposition on identification through immunochromatographic tests for blood and semen, DNA isolation, and STR profiling from these samples...
March 20, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38542142/-dig-up-primers-a-pipeline-for-identification-of-polymorphic-microsatellites-loci-within-assemblies-of-related-species
#8
JOURNAL ARTICLE
Ante Turudić, Zlatko Liber, Martina Grdiša, Jernej Jakše, Filip Varga, Igor Poljak, Zlatko Šatović
Simple sequence repeats (SSRs) have become one of the most popular molecular markers and are used in numerous fields, including conservation genetics, population genetic studies, and genetic mapping. Advances in next-generation sequencing technology and the growing amount of genomic data are driving the development of bioinformatics tools for SSR marker design. These tools work with different combinations of input data, which can be raw reads or assemblies, and with one or more input datasets. We present here a new strategy and implementation of a simple standalone pipeline that utilizes more than one assembly for the in silico design of PCR primers for microsatellite loci in more than one species...
March 9, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38541665/consumption-of-citric-acid-by-bees-promotes-the-gland-development-and-enhances-royal-jelly-quality
#9
JOURNAL ARTICLE
Xue Wang, Quanzhi Ji, Xing Zheng, Jun Zhang, Rongshen Wang, Xinyu Wang, Wenjun Peng, Jun Guo, Yazhou Zhao
The glands of bees are responsible for generating and secreting various biologically active substances that significantly impact bee physiological health and adaptability. This study aimed to investigate the effects of adding citric acid (CA) to bee feed on gland development and royal jelly quality. By formulating feed with varying proportions of CA, evaluation was undertaken of pollen feeding by honeybees under laboratory conditions, along with the impact of CA on the development of major glands, to determine suitable addition proportions...
March 6, 2024: Life
https://read.qxmd.com/read/38541416/novel-additives-in-copper-electrorefining-small-laboratory-scale
#10
JOURNAL ARTICLE
Patrycja Kowalik, Dorota Kopyto, Katarzyna Leszczyńska-Sejda, Wojciech Simka
This research aimed to evaluate the effectiveness of new organic substances, including a novel ionic liquid based on polyhexamethylenebiguanidine, polyhexamethyleneguanidine, and safranin in the copper electrorefining process. Experiments were conducted on a small laboratory scale using industrial copper anodes. Single doses of new additives did not improve process indicators (current efficiency, average cell voltage, specific energy consumption) or the quality of copper cathode deposits. However, a combination of a new ionic liquid based on polyhexamethylenebiguanidine and thiourea resulted in a satisfactory current efficiency of 97%, an average cell voltage of 0...
March 8, 2024: Materials
https://read.qxmd.com/read/38541153/development-of-a-new-bioequivalent-omeprazole-product
#11
JOURNAL ARTICLE
Gulzina Kumisbek, David Vetchý, Arshyn Kadyrbay
Background and Objectives: The enteric form of omeprazole is one of the most commonly prescribed medications. Similarly to Europe, Kazakhstan relies on the localization of pharmaceutical drug production as one of its primary strategies to ensure that its population has access to affordable and good-quality medicines. This study comprehensively describes the technologically available development of bioequivalent delayed-release omeprazole. Materials and Methods: Various regimes and technological parameters were tested on laboratory- and production-scale equipment to establish a technical process where a functional and gastro-protective layer is essential...
March 2, 2024: Medicina
https://read.qxmd.com/read/38541078/early-detection-of-atrial-fibrillation-in-chronic-obstructive-pulmonary-disease-patients
#12
REVIEW
Stanislav Kotlyarov, Alexander Lyubavin
Atrial fibrillation (AF) is an important medical problem, as it significantly affects patients' quality of life and prognosis. AF often complicates the course of chronic obstructive pulmonary disease (COPD), a widespread disease with heavy economic and social burdens. A growing body of evidence suggests multiple links between COPD and AF. This review considers the common pathogenetic mechanisms (chronic hypoxia, persistent inflammation, endothelial dysfunction, and myocardial remodeling) of these diseases and describes the main risk factors for the development of AF in patients with COPD...
February 20, 2024: Medicina
https://read.qxmd.com/read/38540724/role-of-dnase-activity-in-human-sperm-dna-fragmentation
#13
REVIEW
Jaime Gosálvez, Carmen López Fernández, Stephen D Johnston, Javier Bartolomé-Nebreda
In this clinical era of intracytoplasmic sperm injection (ICSI), where a single spermatozoon is chosen for fertilization, the diagnostic functionality of the classical parameters typically associated with fertilization, such as sperm concentration, sperm motility, acrosome integrity, and mitochondria, is perhaps becoming less critical. In contrast, the contribution of sperm DNA quality to our understanding of the impact of male fertility within the context of ICSI is gaining increasing interest and importance...
March 4, 2024: Biomolecules
https://read.qxmd.com/read/38539145/relationships-between-pig-farm-management-and-facilities-and-lung-lesions-scores-and-between-lung-lesions-scores-and-carcass-characteristics
#14
JOURNAL ARTICLE
Zbigniew Kuberka, John F Mee, Aurelia Walaszek-Kayaoglu, Małgorzata D Klimowicz-Bodys, Arkadiusz Dors, Anna Rząsa
BACKGROUND: The objective of this study was to examine the inter-relationships between pig farm management and facilities (as assessed by questionnaire) and post-mortem lung lesion (lung score assesment), which are the result of respiratory infections. The relationships between carcass characteristics and post-mortem lung lesion scores were also investigated. RESULTS: Questionnaire responses were collected from 22 self-selecting pig farmers about their farm facilities/management and health condition of the respiratory system of pigs, including the occurrence of clinical respiratory signs, results of laboratory testing for respiratory pathogens, and the use of respiratory vaccines...
March 28, 2024: BMC Veterinary Research
https://read.qxmd.com/read/38538529/preliminary-study-on-yeasts-associated-with-the-production-of-tostado-a-traditional-sweet-wine-from-galicia-nw-spain
#15
JOURNAL ARTICLE
David Castrillo, Pilar Blanco
BACKGROUND: Tostado is a traditional sweet wine from the Designations of Origins (DOs) of Ribeiro and Valdeorras in Galicia (NW Spain). The harvested grapes are air-dried and pressed to increase the concentrations of sugars, acids, and flavour compounds. Therefore, knowledge of the yeasts involved in fermentation under these conditions is essential to guarantee the quality and uniqueness of the valuable, distinctive, and expensive Tostado wines. METHODS: Saccharomyces and non- Saccharomyces yeasts were identified using Wallerstein Laboratory (WL) Nutrient Agar and lysine plating, followed by polymerase chain reaction (PCR) amplification, enzymatic digestion, and sequencing...
March 14, 2024: Frontiers in Bioscience (Elite Edition)
https://read.qxmd.com/read/38537507/differential-host-responses-to-covid-19-unraveling-the-complexity
#16
JOURNAL ARTICLE
Vinod Kumar Verma, Rahul Yadav, Syed Sultan Beevi, Annie S Mohod, Shravya Mancharla, Neha Damodar, Radhika Chowdary Darapuneni, Sukurtha Gopal Reddy, Pavani Upendram, Mohammad Nawaz Salt, Praveen Kulkarni, Sambit Sahu, Bhaskar Rao Bollineni
These diverse outcomes of Covid-19 are influenced by various factors including age, gender, underlying health conditions, immune responses, viral variants, external factors, and overall quality of life. Demographic analysis of patients aged 0-18 years experienced mild to moderate cases, above 55 years with co-morbidities, were more severely affected.COVID-19 incidence was higher in males (58 %) & (42 %) in females. The reduced expression of Toll-like receptors (TLR) in severe and critical patients is a crucial determinant...
March 24, 2024: Diagnostic Microbiology and Infectious Disease
https://read.qxmd.com/read/38537044/toxoplasmosis-outbreak-in-s%C3%A3-o-paulo-brazil-epidemiology-and-visual-outcome
#17
JOURNAL ARTICLE
Luciana Peixoto Santos Finamor, Geraldine Madalosso, José Eduardo Levi, Yuslay Fernández Zamora, Gabriela Akemi Kamioka, Paula Marinho, Heloisa Nascimento, Cristina Muccioli, Rubens Belfort
PURPOSE: To describe a 2019 acute toxoplasmosis outbreak in the city of São Paulo, Brazil, and to evaluate the laboratory serological profile for toxoplasmosis for three consecutive years. The ophthalmological manifestations of the patients involved in the outbreak were also studied. METHODS: A cross-sectional descriptive study of a toxoplasmosis outbreak in São Paulo, Brazil, between February and May 2019. Epidemiological data were described, as were the observed ocular manifestations...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38536468/traumatic-rhabdomyolysis-rare-but-morbid-potentially-lethal-and-inconsistently-monitored
#18
JOURNAL ARTICLE
Thomas Giles, Kate King, Simone Meakes, Natasha Weaver, Zsolt J Balogh
PURPOSE: Although traumatic rhabdomyolysis (TR) is shown to be associated with acute kidney injury (AKI), there are no large prospective epidemiological studies, interventional trials, official guidelines outlining the appropriate investigation, monitoring, and treatment on this poorly understood condition. We aimed to establish the contemporary epidemiology and describe current practices for TR to power future higher quality studies. We hypothesised that investigation and monitoring occur in an ad hoc fashion...
March 27, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38535901/chemical-assessment-of-drinking-water-quality-and-associated-human-health-risk-of-heavy-metals-in-gutai-mountains-romania
#19
JOURNAL ARTICLE
Thomas Dippong, Maria-Alexandra Resz
Chemical data compiled from field and laboratory studies were analysed on drinking water sources from a mountain area (Gutai Mountains) in Romania. Six physico-chemical indicators, nine anions, and twenty-one metals were determined and analysed. The results of this study showed that waters are generally rich in NH4 + and NO2 - , exceeding the recommended limit of 0.5 mg NH4 + /L, while some waters are rich in As, Cd, Mn and Pb, but with concentrations below the limits concerning the use of waters with drinking purposes...
February 22, 2024: Toxics
https://read.qxmd.com/read/38535153/data-fusion-of-rgb-and-depth-data-with-image-enhancement
#20
JOURNAL ARTICLE
Lennard Wunsch, Christian Görner Tenorio, Katharina Anding, Andrei Golomoz, Gunther Notni
Since 3D sensors became popular, imaged depth data are easier to obtain in the consumer sector. In applications such as defect localization on industrial objects or mass/volume estimation, precise depth data is important and, thus, benefits from the usage of multiple information sources. However, a combination of RGB images and depth images can not only improve our understanding of objects, capacitating one to gain more information about objects but also enhance data quality. Combining different camera systems using data fusion can enable higher quality data since disadvantages can be compensated...
March 21, 2024: Journal of Imaging
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