keyword
MENU ▼
Read by QxMD icon Read
search

Neuroleptic malignant syndrom

keyword
https://www.readbyqxmd.com/read/28045840/acute-dystonia-versus-neuroleptic-malignant-syndrome-without-fever-in-an-eight-year-old-child
#1
Rita Sridaran, Chadd E Nesbit
Neuroleptic malignant syndrome (NMS) is a rare but potentially fatal complication of the use of certain medications. It is being seen more often in the pediatric population because of the increasing use of both typical and atypical antipsychotics in children. Rapid recognition of NMS is important to emergency physicians because timely treatment can be life saving. Acute dystonia is also a well-known and more common adverse effect of certain types of antipsychotics, more commonly seen with the typical antipsychotics versus the atypical antipsychotics...
January 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28027111/a-validation-study-of-the-international-consensus-diagnostic-criteria-for-neuroleptic-malignant-syndrome
#2
Ronald J Gurrera, Gino Mortillaro, Varadaraj Velamoor, Stanley N Caroff
BACKGROUND: Neuroleptic malignant syndrome requires prompt recognition for effective management, but there are no established diagnostic criteria. This is the first validation study of recently published international expert consensus (IEC) diagnostic criteria, which include priority points assigned on the basis of the importance of each criterion for making a diagnosis of neuroleptic malignant syndrome. METHODS: Data were extracted from 221 archived telephone contact reports of clinician-initiated calls to a national telephone consultation service from 1997 to 2009; each case was given a total priority point score on the basis of the IEC criteria...
February 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/27992257/agitation-management-in-pediatric-males-with-anti-n-methyl-d-aspartate-receptor-encephalitis
#3
Lauren T Schumacher, Andrea P Mann, James G MacKenzie
OBJECTIVES: Severe agitation is a common symptom in pediatric cases of anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis-an autoimmune encephalitis with prominent neuropsychiatric symptoms. Agitation is a major barrier to treatment of the underlying disease process and increases patients' risk of harming themselves and others. Furthermore, male patients often have undetectable tumors and are especially at risk for extended hospitalization, but have been infrequently studied...
December 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27964751/neurotoxicity-and-nephrotoxicity-caused-by-combined-use-of-lithium-and-risperidone-a-case-report-and-literature-review
#4
Chih-Wei Hsu, Yu Lee, Chun-Yi Lee, Pao-Yen Lin
BACKGROUND: Combination lithium, a mood stabilizer, and risperidone, an atypical antipsychotic drug, is widely used for treatment of psychotic disorders. Rare reports concern severe adverse drug reaction in multiple organic systems with their combined use. We report two episodes of neurotoxicity and nephrotoxicity in a patient following the combined use of lithium and risperidone. CASE PRESENTATION: A 55-year-old male had a diagnosis of schizoaffective disorder at the age of 51...
December 14, 2016: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/27931201/probable-clozapine-induced-parenchymal-lung-disease-and-perimyocarditis-a-case-report
#5
Erlend Bugge, Trygve Nissen, Rolf Wynn
BACKGROUND: Clozapine is the archetypical atypical antipsychotic, its primary indication being treatment resistant schizophrenia. Severe side effects caused by clozapine, including leukopenia, agranulocytosis, and myocarditis, are well known. A rarely described side effect is concurrent perimyocarditis and parenchymal lung disease. CASE PRESENTATION: A previously physically healthy 23-year-old male Caucasian that suffered from schizophrenia presented with flu-like symptoms 1 week after starting clozapine treatment...
December 8, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27916449/a-case-of-severe-movement-disorder-with-gnao1-mutation-responsive-to-topiramate
#6
Saori Sakamoto, Yukifumi Monden, Ryoko Fukai, Noriko Miyake, Hiroshi Saito, Akihiko Miyauchi, Ayumi Matsumoto, Masako Nagashima, Hitoshi Osaka, Naomichi Matsumoto, Takanori Yamagata
We report the case of a 19-year-old female patient who had progressive chorea associated with a GNAO1 mutation. Chorea was refractory to multiple anticonvulsants, and the patient suffered from tiapride-induced neuroleptic malignant syndrome. After identification of a GNAO1 missense mutation at the age of 18years, topiramate treatment was initiated and the frequency of chorea decreased dramatically. The efficacy of topiramate may have been related to the inhibitory modulation of voltage-activated Ca(2+) channels...
December 1, 2016: Brain & Development
https://www.readbyqxmd.com/read/27863115/reversible-splenial-lesion-syndrome-with-a-hyperosmolar-hyperglycemic-state-and-neuroleptic-malignant-syndrome-caused-by-olanzapine
#7
Kenta Kaino, Ryo Kumagai, Shoko Furukawa, Momoko Isono, Aiko Muramatsu, Masanao Fujii, Yumiko Muta, Tomoyuki Asada, Kazuya Fujihara, Hiroaki Yagyu
A 27-year-old woman with panic disorder taking 20 mg olanzapine daily for 4 months was admitted to our hospital because of disturbed consciousness with fever, hyperglycemia, hyperosmolarity, and elevated creatine phosphokinase. She was diagnosed with a hyperosmolar hyperglycemic state (HHS) and neuroleptic malignant syndrome (NMS). Brain magnetic resonance imaging (MRI) showed transiently restricted diffusion in the splenium of the corpus callosum (SCC), with a high signal intensity on diffusion-weighted imaging...
November 18, 2016: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/27861195/risperidone-associated-rhabdomyolysis-without-neuroleptic-malignant-syndrome-a-case-report
#8
Mei Ling Look, Yang Liang Boo, Pek Woon Chin, Fan Kee Hoo
No abstract text is available yet for this article.
February 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/27824785/commentary-on-3-unusual-cases-involving-electroconvulsive-therapy
#9
David A Kahn
Well-established practice guidelines and a solid body of evidence underpin the safe and effective use of electroconvulsive therapy (ECT), primarily in mood disorders. In this issue of the journal, 3 case reports deal with situations that fall outside of the usual guidelines: treatment resistance to ECT overcome by combined use with antidepressant medication; use of ECT in the presence of polymyositis; and use of ECT for an unusually severe case of neuroleptic malignant syndrome, assisted by consultation from an online expert resource...
November 2016: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/27824784/use-of-expert-consultation-in-a-complex-case-of-neuroleptic-malignant-syndrome-requiring-electroconvulsive-therapy
#10
Justine Wittenauer Welsh, A Umair Janjua, Steven J Garlow, Laurie McCormick, Mustafa M Husain, Daniel F Maixner, Richard D Weiner, Adriana P Hermida
Our team at Emory University Hospital contacted experts at the National Network of Depression Centers (NNDC) for clinical guidance concerning a patient with schizophrenia hospitalized in the intensive care unit with a complex case of prolonged delirium secondary to neuroleptic malignant syndrome (NMS). Through the NNDC, leading psychiatrists across the United States with expertise in electroconvulsive therapy (ECT) provided us with treatment strategies based on experience in our area of concern. This report describes our use of ECT to treat severe NMS in this patient with schizophrenia, utilizing the recommendations made by the NNDC's ECT experts concerning electrode position, number and frequency of treatments, and selection of anesthetic induction agents...
November 2016: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/27776396/venous-thromboembolism-following-dantrolene-treatment-for-neuroleptic-malignant-syndrome
#11
Po-Hao Chen, Hsien-Yuan Lane, Chieh-Hsin Lin
Neuroleptic malignant syndrome (NMS) is one of the most severe iatrogenic emergencies in clinical service. The symptoms including sudden consciousness change, critical temperature elevation and electrolytes imbalance followed by mutli-organ system failure were common in NMS. In addition to aggressive interventions with intravenous fluid resuscitation and antipyretics, several antidotes have been suggested to prevent further progression of the muscle damage. Dantrolene has been reported to be one of the most effective treatments for NMS...
November 30, 2016: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27773902/posterior-reversible-encephalopathy-syndrome-in-parkinson-disease-probably-caused-by-prominent-supine-hypertension-and-blood-pressure-fluctuation
#12
Saori Morozumi, Shigenori Kato, Keizo Yasui, Yasuhiro Hasegawa
We present the case of a 77-year-old man with a 10-year history of Parkinson disease (PD), who developed posterior reversible encephalopathy syndrome (PRES). We diagnosed the case as PRES based on clinical features and MRI findings. He experienced orthostatic hypotension and supine hypertension, including nocturnal hypertension. PRES may result from marked supine/nocturnal hypertension and fluctuation in blood pressure. In addition, exacerbated factors could be representative of neuroleptic malignant syndrome...
November 29, 2016: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/27725556/catatonic-symptoms-appearing-before-autonomic-symptoms-help-distinguish-neuroleptic-malignant-syndrome-from-malignant-catatonia
#13
Takayuki Komatsu, Tomohisa Nomura, Hiroki Takami, So Sakamoto, Keiko Mizuno, Hajime Sekii, Kotaro Hatta, Manabu Sugita
A 42-year-old Japanese woman with a 10-year history of schizophrenia was admitted due to a disturbance in consciousness that met the diagnostic criteria for both neuroleptic malignant syndrome (NMS) and malignant catatonia. Despite systemic supportive treatments, the catatonic symptoms preceding autonomic symptoms persisted. The symptoms improved after lorazepam administration, leading to a retrospective diagnosis of malignant catatonia. Catatonia is thought to be caused by a dysfunction of ganmma-aminobutyric acid type A receptors in the cortico-cortical networks of the frontal lobes, which causes hypoactivity of the dopaminergic transmission in the subcortical areas...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27721999/paliperidone-inducing-concomitantly-syndrome-of-inappropriate-antidiuretic-hormone-neuroleptic-malignant-syndrome-and-rhabdomyolysis
#14
Jaspinder Kaur, Dileep Kumar, Mostafa Alfishawy, Ricardo Lopez, Issac Sachmechi
Paliperidone, an active metabolite of risperidone, is a new atypical antipsychotic agent. Syndrome of inappropriate antidiuretic hormone (SIADH), neuroleptic malignant syndrome (NMS), and rhabdomyolysis are the uncommon side effects of psychotropic drugs. We report a case of 35-year-old male with schizoaffective disorder who was admitted for acute-on-chronic exacerbation of his psychotic disorder for which intramuscular paliperidone 234 mg injection was given. Two days later, the patient developed hyponatremic seizures secondary to SIADH which was treated with hypertonic saline...
2016: Case Reports in Critical Care
https://www.readbyqxmd.com/read/27685194/mild-hypothermia-in-a-child-with-low-dose-risperidone
#15
Katharina Grau, Paul L Plener, Maximilian Gahr, Christian Denzer, Roland W Freudenmann
Risperidone is a widely used, second-generation antipsychotic approved for treating schizophrenia as well as for treating aggression in children and adolescents with mental retardation. The substance has a well-established risk profile including alterations of body temperature. Apart from hyperthermia with and without full-blown malignant neuroleptic syndrome, low body temperatures (hypothermia) have also been reported anecdotally, usually appearing in the context of comedication. Here, we report a case of hypothermia associated with a low-dose risperidone monotherapy in a child...
September 29, 2016: Zeitschrift Für Kinder- und Jugendpsychiatrie und Psychotherapie
https://www.readbyqxmd.com/read/27626284/olanzapine-long-acting-injections-after-neuroleptic-malignant-syndrome-two-case-reports
#16
Marina Šagud, Bjanka Vuksan-Ćusa, Nada Božina, Mila Lovrić, Alma Mihaljević-Peleš, Milivoj Kramarić
No abstract text is available yet for this article.
December 2016: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/27625493/carisoprodol-withdrawal-syndrome-resembling-neuroleptic-malignant-syndrome-diagnostic-dilemma
#17
Gunchan Paul, Gautam L Parshotam, Rajneesh Garg
Soma (Carisoprodol) is N-isopropyl-2 methyl-2-propyl-1,3-propanediol dicarbamate; a commonly prescribed, centrally acting skeletal muscle relaxant. Neuroleptic malignant syndrome (NMS) is a potentially life-threatening adverse effect of antipsychotic agents. Although diagnostic criteria for NMS have been established, it should be recognized that atypical presentations occur and more flexible diagnostic criteria than currently mandated, may be warranted. We wish to report a postoperative case of bilateral knee replacement who presented with carisoprodol (Soma) withdrawal resembling NMS that was a diagnostic dilemma...
July 2016: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/27606070/diagnosis-and-implications-in-the-therapeutic-management-of-patient-with-afebrile-neurolepctic-malignant-syndrome
#18
Rafael Quintes Ducasble Gomes, Amilton Dos Santos-Júnior, Gabriel Augusto de Araujo Silva Dias, Carlos Filinto da Silva Cais
This report aims at raising clinical awareness for the diagnosis of atypical presentations of neuroleptic malignant syndrome (NMS). We describe the case of a female patient with NMS symptoms, except fever, after starting the use of chlorpromazine. The afebrile condition delayed the consideration of NMS by the emergency clinicians who provided her initial assessment. Before this consideration, an anticholinergic agent, not recommended at this condition, was inadvertently prescribed. This might have contributed to the worsening of symptoms...
September 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/27598893/reconsidering-olanzapine-as-a-possible-culprit-for-drug-fever-defying-incomplete-neuromalignant-syndrome
#19
Alan Georges, Mary Jo Fitz-Gerald
This case is important because it is the first time Olanzapine-induced fever has been described in the absence of neuroleptic malignant syndrome. In the context of the available antipsychotics with the atypical agents dominating the pool, only few of those are known to be well tolerated among the patients. Fever may be looked at by the physicians as a minor problem yet, it can be disabling to the large set of patients. Fever was not considerably listed as one of the side effects for Olanzapine and should not be confused with the incomplete neuromalignant syndrome...
July 2016: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/27590992/anti-n-methyl-d-aspartate-receptor-encephalitis-a-potential-mimic-of-neuroleptic-malignant-syndrome
#20
Margaret Rozier, Denise Morita, Marta King
BACKGROUND: Anti-N-methyl-D-aspartate receptor encephalitis is an autoimmune disorder characterized by behavioral changes, dyskinesia, and autonomic instability. PATIENT DESCRIPTION: We describe a 14-year-old girl who initially presented with acute behavioral changes and seizures and who over a 2-week period developed high fever, tachycardia, and elevated blood pressures. RESULTS: Because she received multiple medications including anticonvulsants and a neuroleptic, our patient was initially diagnosed with neuroleptic malignant syndrome, a disorder characterized by autonomic dysfunction, hyperthermia, muscle rigidity, and mental status changes usually caused by the use of a neuroleptic agent...
October 2016: Pediatric Neurology
keyword
keyword
46640
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"