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https://www.readbyqxmd.com/read/28198763/impact-of-role-stressors-on-the-health-of-nurse-managers-a-western-canadian-context
#1
Sonia A Udod, Greta Cummings, W Dean Care, Megan Jenkins
OBJECTIVE: A qualitative exploratory inquiry was used to understand nurse managers' (NMs') perceptions of their role stressors, coping strategies, and self-health related outcomes as a result of frequent exposure to stressful situations in their role. BACKGROUND: Strong nursing leadership is required for desirable staff, patient, and organizational outcomes. A stressed NM will negatively influence staff nurse satisfaction and retention, patient outcomes, and organizational performance...
March 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28198761/emotional-intelligence-of-nurse-managers-an-exploratory-study
#2
Patricia Prufeta
OBJECTIVE: The purposes of this study are to determine the level of emotional intelligence (EI) among nurse managers (NMs) in an academic medical center and determine the relationship of EI and demographic variables. BACKGROUND: Emotional intelligence is a concept that warrants further research in nursing because there is a huge gap in knowledge about nurse leaders' EI. METHODS: Data were collected from 38 NMs recruited from a large academic medical center in the Northeast...
March 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28195174/photocatalytic-tmo-nms-adsorbent-temperature-time-dependent-safranine-degradation-sorption-study-validated-under-optimized-effective-equilibrium-models-parameter-with-standardized-statistical-analysis
#3
Rizwan Wahab, Farheen Khan, Nagendra Kumar Kaushik, Javed Musarrat, Abdulaziz A Al-Khedhairy
In this paper, chemically synthesized copper oxide nanoparticles (CuO-NPs), were employed for two processes: one is photocatalytic degradation and second one adsorption for the sorption of safranine (SA) dye in an aqueous medium at pH = 12.01. The optimized analytes amount (nano-adsorbent = 0.10 g, conc. range of SA dye 56.13 ppm to 154.37 ppm, pH = 12.01, temperature 303 K) reached to equilibrium point in 80 min, which acquired for chemical adsorption-degradation reactions. The degredated SA dye data's recorded by UV-visible spectroscopy for the occurrence of TMO-NMs of CuO-NPs at anticipated period of interval...
February 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28185878/chronic-mild-stress-augments-mptp-induced-neurotoxicity-in-a-murine-model-of-parkinson-s-disease
#4
Udaiyappan Janakiraman, Thamilarasan Manivasagam, Arokiasamy Justin Thenmozhi, Chinnasamy Dhanalakshmi, Musthafa Mohamed Essa, Byoung-Joon Song, Gilles J Guillemin
Depression is frequently encountered during Parkinson's disease (PD) as a non-motor feature, which has been reported to cause and exaggerate motor deficits and neurodegenerative events in experimental PD models. We studied the effect of chronic mild stress (CMS) (pre, post and pre & post) exposure mediated depression on motor and non-motor symptoms, oxidative stress, inflammation and brain derived neurotrophic factor (BDNF) levels and its related signalling molecules against the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid (MPTP/p) induced neurotoxicity in mice...
February 6, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28166876/development-of-a-usability-evaluation-method-using-natural-product-use-motion
#5
Joonho Chang, Kihyo Jung, Wonsup Lee, Heecheon You
The present study developed and tested a new usability evaluation method which considers natural product-use motions. The proposed method measures both natural product-use motions (NMs) and actual product-use motions (AMs) for a product using an optical motion capture system and examines the usability of the product based on motion similarity (MS; %) between NMs and AMs. The proposed method was applied to a usability test of four vacuum cleaners (A, B, C, and D) with 15 participants and their MSs were compared with EMG measurements and subjective discomfort ratings...
April 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28164167/neonatal-maternal-separation-increases-susceptibility-to-experimental-colitis-and-acute-stress-exposure-in-male-mice
#6
Isabella M Fuentes, Natalie K Walker, Angela N Pierce, Briana R Holt, Elizabeth R Di Silvestro, Julie A Christianson
Experiencing early life stress can result in maladjusted stress response via dysregulation of the hypothalamic-pituitary-adrenal axis and serves as a risk factor for developing chronic pelvic pain disorders. We investigated whether neonatal maternal separation (NMS) would increase susceptibility to experimental colitis or exposure to acute or chronic stress. Male mice underwent NMS from postnatal day 1-21 and as adults were assessed for open field behavior, hindpaw sensitivity, and visceromotor response (VMR) to colorectal distension (CRD)...
December 2016: IBRO Rep
https://www.readbyqxmd.com/read/28150102/adaptation-and-psychometric-properties-of-the-italian-version-of-the-non-motor-symptoms-questionnaire-for-parkinson-s-disease
#7
I Cova, M E Di Battista, N Vanacore, C P Papi, G Alampi, A Rubino, M Valente, G Meco, P Contri, A Di Pucchio, E Lacorte, A Priori, C Mariani, S Pomati
Although non-motor symptoms (NMS) of Parkinson's disease (PD) are very common also in early stages of the disease, they are still under-recognized. Screening tools for non-motor symptoms, such as non-motor symptoms questionnaire (NMSQuest), help clinicians to recognize NMS and to evaluate if patients could require further assessment or specific treatments. To validate an adapted Italian version of NMSQuest and study its psychometric properties, Italian PD patients self-completed Italian NMSQuest, and then underwent a standard clinical evaluation including motor assessment (by Hoehn and Yahr staging, unified Parkinson's disease rating scale part III) and non-motor assessment (by Montreal cognitive assessment, Beck depression inventory, neuropsychiatric inventory, Epworth sleepiness scale, scale for outcomes in Parkinson's disease-Autonomic and movement disorder society-sponsored revision of the unified Parkinson's disease rating scale part I)...
February 1, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28144982/a-systematic-review-of-sex-and-age-factors-in-neuroleptic-malignant-syndrome-diagnosis-frequency
#8
Ronald J Gurrera
OBJECTIVE: To examine sex and age distributions in neuroleptic malignant syndrome (NMS) patients based on a systematic literature review. METHOD: EMBASE and PubMed databases were searched to identify any observation of NMS published from January 1, 1998 through November 1, 2014 that was accessible and interpretable (using language translation software). Redundant and equivocal reports were excluded. Sex ratio and age distributions were examined using standard graphical techniques and measures of association...
February 1, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28138117/neuroleptic-malignant-syndrome-associated-with-valproate-in-an-adolescent
#9
Veli Yıldırım, Meltem Çobanogulları Direk, Serkan Güneş, Çetin Okuyaz, Fevziye Toros
Neuroleptic malignant syndrome (NMS) is a life-threatening idiosyncratic reaction that usually occurs after the administration of antipsychotic drugs. Antidepressants, benzodiazepines, and antiepileptic drugs are also suggested to be associated with NMS. It is believed to result from a dopaminergic blockade in the central nervous system. NMS is manifested by hyperthermia, muscle rigidity, autonomic dysfunction, altered mental status, leukocytosis, and elevated serum creatinine phosphokinase. Valproate is commonly used in the treatment of many psychiatric and neurologic disorders...
February 28, 2017: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28129906/prospecting-nanomaterials-in-aqueous-environments-by-cloud-point-extraction-coupled-with-transmission-electron-microscopy
#10
Yu Yang, Robert Reed, Jared Schoepf, Kiril Hristovski, Pierre Herckes, Paul Westerhoff
Increasing application of engineered nanomaterials (ENMs) in industry and consumer products inevitably lead to their release into and impact on aquatic environments. To characterize the NMs efficiently in surface water, a fast and simple method is needed to separate and concentrate nanomaterials from the aqueous matrix without altering their shape and size. Applying cloud-point extraction (CPE) using the surfactant Triton 114 to an array of NMs (titanium dioxide, gold, silver, and silicon dioxide) with different sizes or capping agents in nanopure water resulted in extraction efficiency of 83%-107%...
January 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28128044/role-stressors-and-coping-strategies-among-nurse-managers
#11
Sonia Udod, Greta G Cummings, W Dean Care, Megan Jenkins
Purpose The purpose of this paper is to share preliminary evidence about nurse managers' (NMs) role stressors and coping strategies in acute health-care facilities in Western Canada. Design/methodology/approach A qualitative exploratory inquiry provides deeper insight into NMs' perceptions of their role stressors, coping strategies and factors and practices in the organizational context that facilitate and hinder their work. A purposeful sample of 17 NMs participated in this study. Data were collected through individual interviews and a focus group interview...
February 6, 2017: Leadership in Health Services
https://www.readbyqxmd.com/read/28126371/effect-of-nano-zno-on-biogas-generation-from-simulated-landfills
#12
İlknur Temizel, S Mehdi Emadian, Martina Di Addario, Turgut T Onay, Burak Demirel, Nadim K Copty, Tanju Karanfil
Extensive use of nanomaterials in commercial consumer products and industrial applications eventually leads to their release to the waste streams and the environment. Nano-ZnO is one of the most widely-used nanomaterials (NMs) due to its unique properties. It is also known to impact biological processes adversely. In this study, the effect of nano-ZnO on biogas generation from sanitary landfills was investigated. Two conventional and two bioreactor landfills were operated using real MSW samples at mesophilic temperature (35°C) for a period of about 1year...
January 23, 2017: Waste Management
https://www.readbyqxmd.com/read/28123608/the-novel-pim1-inhibitor-nms-p645-reverses-pim1-dependent-effects-on-tmprss2-erg-positive-prostate-cancer-cells-and-shows-anti-proliferative-activity-in-combination-with-pi3k-inhibition
#13
Luca Mologni, Vera Magistroni, Francesco Casuscelli, Marisa Montemartini, Carlo Gambacorti-Passerini
PIM1 is over-expressed in multiple tumors, including prostate cancer (PCa). PIM1 upregulation is mediated by direct binding of the ERG transcription factor to its promoter. About 50% of PCa cases are characterized by the presence of the TMPRSS2/ERG fusion, leading to ERG over-expression and thus to PIM1 transcriptional activation. PIM kinases are considered as weak oncogenes, but when combined with additional genetic alterations can induce strong transforming effects. Here we show anti-proliferative activity of the newly described PIM1 inhibitor NMS-P645 in combination with the PI3K inhibitor GDC-0941 in TMPRSS2/ERG positive and negative PCa cells...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28115205/mechanism-of-ros-scavenging-and-antioxidant-signalling-by-redox-metallic-and-fullerene-nanomaterials-potential-implications-in-ros-associated-degenerative-disorders
#14
REVIEW
Mohd Javed Akhtar, Maqusood Ahamed, Hisham A Alhadlaq, Aws Alshamsan
BACKGROUND: The balance between oxidation and anti-oxidation is believed to be critical in maintaining healthy biological systems. However, our endogenous antioxidant defense systems are incomplete without exogenous antioxidants and, therefore, there is a continuous demand for exogenous antioxidants to prevent stress and ageing associated disorders. Nanotechnology has yielded enormous variety of nanomaterials (NMs) of which metallic and carbonic (mainly fullerenes) NMs, with redox property, have been found to be strong scavengers of ROS and antioxidants in preclinical in vitro and in vivo models...
January 20, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28106222/digestibility-and-supramolecular-structural-changes-of-maize-starch-by-non-covalent-interactions-with-gallic-acid
#15
Chengdeng Chi, Xiaoxi Li, Yiping Zhang, Ling Chen, Lin Li, Zhijiang Wang
The effects of non-covalent interactions between gallic acid (GA) and starch on starch digestibility and supramolecular structural changes (short-range ordered molecular structure, crystalline structure, lamellar structure and fractal structure) were investigated. The results indicated that the digestibility of both starches was substantially reduced in the rapidly digestible starch (RDS) content, but resistant starch (RS) was increased after interacting with GA. The RS content of starch-GA complexes ranged from 17...
January 20, 2017: Food & Function
https://www.readbyqxmd.com/read/28095787/the-effects-of-habitual-functional-training-on-physical-functioning-in-patients-after-hip-fracture-the-protocol-of-the-hipfrac-study
#16
Kristi Elisabeth Heiberg, Vigdis Bruun-Olsen, Astrid Bergland
BACKGROUND: The survivors after hip fracture often report severe pain and loss of physical functioning. The poor outcomes cause negative impact on the person's physical functioning and quality of life and put a financial burden on society. Rehabilitation is important to improve physical functioning after hip fracture. To maintain the continuity in rehabilitation we have an assumption that it is of utmost importance to continue and progress the functional training that already started at the hospital, while the patients are transferred to short-term stays in a nursing home before they are returning to home...
January 17, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28094527/binding-and-inhibitory-effect-of-the-dyes-amaranth-and-tartrazine-on-amyloid-fibrillation-in-lysozyme
#17
Anirban Basu, Gopinatha Suresh Kumar
Interaction of two food colorant dyes, amaranth and tartrazine, with lysozyme was studied employing multiple biophysical techniques. The dyes exhibited hypochromic changes in the presence of lysozyme. The intrinsic fluorescence of lysozyme was quenched by both dyes; amaranth was a more efficient quencher than tartrazine. The equilibrium constant of amaranth was higher than that of tartarzine. From FRET analysis, the binding distances for amaranth and tartrazine were calculated to be 4.51 and 3.93 nm, respectively...
February 3, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28091608/binding-of-n-methylscopolamine-to-the-extracellular-domain-of-muscarinic-acetylcholine-receptors
#18
Jan Jakubík, Alena Randáková, Pavel Zimčík, Esam E El-Fakahany, Vladimír Doležal
Interaction of orthosteric ligands with extracellular domain was described at several aminergic G protein-coupled receptors, including muscarinic acetylcholine receptors. The orthosteric antagonists quinuclidinyl benzilate (QNB) and N-methylscopolamine (NMS) bind to the binding pocket of the muscarinic acetylcholine receptor formed by transmembrane α-helices. We show that high concentrations of either QNB or NMS slow down dissociation of their radiolabeled species from all five subtypes of muscarinic acetylcholine receptors, suggesting allosteric binding...
January 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28088171/assessing-the-sustainability-of-daily-chlorhexidine-bathing-in-the-intensive-care-unit-of-a-veteran-s-hospital-by-examining-nurses-perspectives-and-experiences
#19
Jackson S Musuuza, Tonya J Roberts, Pascale Carayon, Nasia Safdar
BACKGROUND: Daily bathing with chlorhexidine gluconate (CHG) of intensive care unit (ICU) patients has been shown to reduce healthcare-associated infections and colonization by multidrug resistant organisms. The objective of this project was to describe the process of daily CHG bathing and identify the barriers and facilitators that can influence its successful adoption and sustainability in an ICU of a Veterans Administration Hospital. METHODS: We conducted 26 semi-structured interviews with a convenience sample of 4 nurse managers (NMs), 13 registered nurses (RNs) and 9 health care technicians (HCTs) working in the ICU...
January 14, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28079981/inhibiting-solid-tumor-growth-in-vivo-by-non-tumor-penetrating-nanomedicine
#20
Shixian Lv, Zhaohui Tang, Wantong Song, Dawei Zhang, Mingqiang Li, Huaiyu Liu, Jianjun Cheng, Wu Zhong, Xuesi Chen
Nanomedicine (NM) cannot penetrate deeply into solid tumors, which is partly attributed to the heterogeneous microenvironment and high interstitial fluid pressure of solid tumors. To improve NM efficacy, there has been tremendous effort developing tumor-penetrating NMs by miniaturizing NM sizes or controlling NM surface properties. But progress along the direction of developing tumor penetrating nanoparticle has been slow and improvement of the overall antitumor efficacy has been limited. Herein, a novel strategy of inhibiting solid tumor with high efficiency by dual-functional, nontumor-penetrating NM is demonstrated...
January 12, 2017: Small
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