keyword
https://read.qxmd.com/read/38277045/-migraine-and-mitochondrial-diseases-energy-deficit-in-the-brain
#21
JOURNAL ARTICLE
Lucia Hämmerl, Torsten Kraya
Mitochondrial diseases are complex metabolic disorders caused by genetic mutations and lead to impaired energy production in the mitochondria of cells. The clinical spectrum ranges from severe multiorgan involvement in early childhood to mild monosymptomatic courses in adulthood. The brain, heart, and skeletal muscles are particularly affected due to their high energy demands. Headaches in general and migraine in particular, occur disproportionately more frequently in patients with mitochondrial diseases. In recent years similarities in the pathomechanism of mitochondrial diseases and migraine have been investigated in numerous biochemical, genetic, and therapeutic studies...
February 2024: Der Nervenarzt
https://read.qxmd.com/read/38272517/subsequent-development-of-kawasaki-disease-following-acute-human-adenovirus-infection-among-siblings
#22
JOURNAL ARTICLE
Ashwini Sankannaavr, Divyashree Puttalinga, Praveen S Bagalkot
We report a middle-childhood girl presented with high-grade fever and headache for 4 days. Following this, the child developed mucocutaneous symptoms. She had a notable family history of autoimmune disease. Tests revealed increased inflammatory markers. On the sixth day of illness, a two-dimensonal echocardiogram showed an enlarged coronary artery, diagnosed as incomplete Kawasaki disease (KD) and treated with IVIG and aspirin.Within a week, her younger sibling, an early-childhood girl presented with features of viral prodrome, developed mucocutaneous lesions and subcutaneous oedema of limbs...
January 24, 2024: BMJ Case Reports
https://read.qxmd.com/read/38256539/therapeutic-strategies-in-children-with-epilepsy-a-quality-of-life-related-perspective
#23
REVIEW
Hideaki Kanemura
Back ground: Children with epilepsy are affected by several factors, including clinical and social variables. Among these variables, cognitive decline and behavioral disturbances, perceptions of stigma, and fatigue can lead to reductions in quality of life (QOL). Epileptic activities, including seizure severity, frequent seizures, and status epilepticus (SE), have been identified as important predictors of QOL. In addition, the frequency of interictal epileptiform discharges (IEDs) on electroencephalogram (EEG) may also be an important predictor of QOL, because IEDs can lead to cognitive decline and behavioral disturbances...
January 11, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38252931/a-large-cirsoid-aneurysm-of-the-scalp-with-multiple-arterial-supply-illustrative-case
#24
JOURNAL ARTICLE
Soumya Pahari, Paawan Bahadur Bhandari, Bibek Bhattarai, Purushottam Baniya, Stuti Yadav, Prarthana Subedi, Sarbind Mandal
BACKGROUND: Cirsoid aneurysm of the scalp is a rare arteriovenous fistula having a traumatic, congenital, iatrogenic, or idiopathic etiology. Its presentation can range from a small swelling to a large pulsatile mass with tinnitus, headache, and scalp necrosis. OBSERVATIONS: A 67-year-old female presented with a gradually increasing swelling on her forehead and head since childhood and no history of trauma. Examination revealed 12 × 5 cm tortuous midline swelling...
January 22, 2024: J Neurosurg Case Lessons
https://read.qxmd.com/read/38225449/pain-site-persistence-and-changes-from-childhood-to-adolescence-a-prospective-cohort-study
#25
JOURNAL ARTICLE
Francisco Fernandes, Makram Talih, Catarina Pires, Naré Navasardyan, Maria José Santos, Raquel Lucas
BACKGROUND: Pain is a complex experience that interferes with the well-being of youth who experience it. We aimed to assess whether recurrent pain sites in childhood can predict later recurrent pain sites prospectively. METHODS: Pain was assessed using the Luebeck Pain Screening Questionnaire at ages 7, 10, and 13 from the Generation XXI cohort. We used multinomial regression to assess the association of recurrent pain sites at ages 7 and 10 with those at age 13...
January 15, 2024: Pediatric Research
https://read.qxmd.com/read/38215234/childhood-primary-stabbing-headache-a-double-center-study
#26
JOURNAL ARTICLE
Gabriele Monte, Laura Papetti, Fabiana Ursitti, Giorgia Sforza, Samuela Tarantino, Martina Checchi Proietti, Daniela D'Agnano, Vittorio Sciruicchio, Massimiliano Valeriani
BACKGROUND: Primary stabbing headache (PSH) is an idiopathic headache disorder characterized by head pain occurring as a transient and localized single stab or a series of stabs. The present study aimed to examine the characteristics of childhood PSH and whether they fit the International Classification of Headache Disorders, 3rd edition (ICHD-3) criteria. We also investigated the association with migraine and episodic syndromes. METHODS: In this retrospective study, we included 60 patients seen at two headache clinics (Rome and Bari) between 2016 and 2022...
January 2024: Cephalalgia: An International Journal of Headache
https://read.qxmd.com/read/38205089/acute-viral-encephalitis-mimicking-idiopathic-intracranial-hypertension-in-an-immunocompetent-obese-adolescent-girl
#27
Ramaning Loni, Abdulaziz H Khushaym, Abdulaziz B Aldoseri, Ali Alfehaid, Gabriel Fox, Shatha Hasan
Varicella zoster virus (VZV) is common worldwide and one of the main causes of infectious encephalitis. We report the case of a 13-year-old girl who presented to the emergency department with complaints of recurrent episodes of vague headaches associated with photophobia multiple times within three days before hospitalization. The patient had a history of morbid obesity without other metabolic complications as well as a history of chicken pox in childhood. Doctors subsequently diagnosed her with increased intracranial pressure owing to suspected VZV encephalitis...
January 2024: Curēus
https://read.qxmd.com/read/38196770/childhood-and-adolescents-sleep-bruxism-treatment-a-systematic-review
#28
REVIEW
Jordana Senff, Danielle Veiga Bonotto, Priscila Brenner Hilgenberg-Sydney, Aline Sebastiani, Rafaela Scariot, Lisa Yurie Oda
Introduction  Sleep Bruxism (SB) is a common condition in childhood that can cause multiple consequences such as abnormal tooth wear, tensional headaches, masticatory muscle pain, or fatigue. The literature reports some interventions, however the treatment for SB in children is not well-established. Objectives  A systematic review was performed to investigate the effectiveness of the treatments described for SB in children and adolescents: pharmacological and psychological treatments; behavioral guidelines; and dental approaches...
September 2023: Sleep Science
https://read.qxmd.com/read/38179378/a-case-of-systemic-lupus-erythematosus-sle-induced-immune-thrombocytopenia-presented-with-a-subdural-hematoma
#29
Diya M Asad, Salem M Tos, Omar R Khalil, Ahmed H Khammash, Abeer A Awesat, Ahmed M Barbarawi, Mohammad A Isa Assadi, Jawad K Alzaatreh, Majd Mohsen, Alaa Qasem
Systemic lupus erythematosus (SLE) is an autoimmune disease that can cause various health problems, including issues with the blood. One common blood-related symptom in SLE is immune thrombocytopenia (ITP), which leads to low platelet counts. In some cases, SLE patients with ITP may develop a rare but serious complication called subdural hematoma (SDH), which is a type of bleeding in the brain. This combination of conditions can be challenging to manage and has a high mortality rate. In a specific case, a 14-year-old girl with chronic ITP developed a sudden headache and was diagnosed with childhood-onset SLE, leading to the development of SDH...
December 2023: Curēus
https://read.qxmd.com/read/38174676/cerebral-echinococcus-that-can-be-confused-with-brain-tumour-a%C3%A2-case-report
#30
Şule Göktürk, Yasin Göktürk
Echinococcus is a parasitic disease known as echinococcal zoonosis and is often caused by Echinococcus granulosus. Cerebral echinococcus is extremely rare and has been reported to be less than 1% in the literature and it is more common in the childhood age group. In the case we are going to present, the patient is an 83-year-old male who was admitted to our clinic with complaints of headache and forgetfulness. The patient, who was initially thought to have a brain tumour, was pathologically diagnosed as echinococcus after surgery...
January 4, 2024: Folia Neuropathologica
https://read.qxmd.com/read/38170047/examining-the-impact-of-puberty-on-primary-headache-disorders-in-female-schoolchildren-a-cross-sectional-study
#31
JOURNAL ARTICLE
Nora Almuslim, Aeshah Alnajjar, Nurah Alkhteeb, Mashael Alhussain, Hanan Alrubaia, Ahmed Alkhateeb
Introduction and aim Headaches are one of the most prevalent childhood disorders. Primary and secondary headaches are the two types of headaches affecting kids and teenagers. The three most typical primary headache forms are tension-type headaches (TTH), migraine, and cluster headaches. This study sought to determine the relationship between puberty and types of headaches. Methods This cross-sectional study was conducted from May 18 to July 31, among female schoolchildren aged between eight and 15 years in the Eastern Province of Saudi Arabia...
December 2023: Curēus
https://read.qxmd.com/read/38161612/circular-configuration-of-torcular-herophili-presenting-as-childhood-headache-2d-computational-fluid-dynamic-analysis-with-a-proposed-mechanism
#32
JOURNAL ARTICLE
Debajyoti Datta, Arunkumar Sekar, Ashis Patnaik
This case report presents a rare anatomical variant of the torcular Herophili, characterized by a circular configuration and the absence of the left transverse sinus. A 12-year-old child presented with intermittent holocranial headaches, and imaging revealed the circular torcular Herophili along with mild ventricular enlargement. The straight sinus drained into the left side of the circular torcular Herophili. Following lumbar puncture and cerebrospinal fluid (CSF) drainage, the child experienced symptom improvement...
December 2023: Asian Journal of Neurosurgery
https://read.qxmd.com/read/38159209/pediatric-head-injuries-particularities-and-neurosurgical-experience-in-a-lower-middle-income-country
#33
JOURNAL ARTICLE
Amine Trifa, Mouna Rkhami, Kais Maamri, Ghassen Elkahla, Ihsen Zammel, Mehdi Darmoul
PURPOSE: To the best of our knowledge, this is the first study conducted in Tunisia on the neurosurgical management of child cranial trauma. The objectives of the present work were to identify the causes of pediatric head injuries, explore epidemiological and clinical specificities, and analyze the short- and long-term postoperative evolution. METHODS: A retrospective review was conducted on one hundred children with head injuries over a five-year period at one of the largest neurosurgery departments in Tunisia...
December 30, 2023: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://read.qxmd.com/read/38136039/how-can-specialist-advice-influence-the-neuroimaging-practice-for-childhood-headache-in-emergency-department
#34
JOURNAL ARTICLE
Alberto M Cappellari, Gaia Bruschi, Gisella B Beretta, Maria T Molisso, Giuseppe Bertolozzi
Differentiating between primary and secondary headaches can be challenging, especially in the emergency department (ED). Since symptoms alone are inadequate criteria for distinguishing between primary and secondary headaches, many children with headaches undergo neuroimaging investigations, such as brain CT and MRI. In various studies, the frequency of neuroimaging utilization is influenced by several factors, including teaching status, ownership, metropolitan area, insurance status, and ethnicity of patients...
November 22, 2023: Children
https://read.qxmd.com/read/38099279/hippocampal-volume-changes-across-developmental-periods-in-female-migraineurs
#35
JOURNAL ARTICLE
Sophie L Wilcox, Sarah Nelson, Allison Ludwick, Andrew M Youssef, Alyssa Lebel, Lino Beccera, Rami Burstein, David Borsook
Brain-related plasticity can occur at a significant rate varying on the developmental period. Adolescence in particular has been identified as a period of growth and change across the structure and function of the nervous system. Notably, research has identified migraines as common in both pediatric and adult populations, but evidence suggests that the phenotype for migraines may differ in these cohorts due to the unique needs of each developmental period. Accordingly, primary aims of this study were to define hippocampal structure in females (7-27 years of age) with and without migraine, and to determine whether this differs across developmental stages (i...
2023: Neurobiology of Pain
https://read.qxmd.com/read/38058957/an-atypical-presentation-of-childhood-paraganglioma-with-seizures-a-case-report-and-review-of-the-literature
#36
Elizabeth Eberechi Oyenusi, Uzoamaka Felicia Nwigbo, Oluwadamilola Moromoke Oladipo, Blessing Ebele Kene-Udemezue, Kasarachi Pauline Akowundu, Khadijah Omobusola Oleolo-Ayodeji, Oluwaseun Adunni Afoke, Funmilayo Oluwatoyin Babatunde, Felix Makinde Alakaloko, Gabriel Kolawole Asiyanbi, Ezekiel Olayiwola Ogunleye, Abiola Olufunmilayo Oduwole, Foluso Ebun Afolabi Lesi
INTRODUCTION: A paraganglioma (PGL) is a tumour derived from extra-adrenal chromaffin cells of the sympathetic paravertebral ganglia of the thorax, abdomen, and pelvis. Cardiovascular manifestations predominate but neurological symptoms like seizures can occur requiring a high index of suspicion for prompt diagnosis and treatment. Case Description . A 14-year-old girl was referred to the paediatric neurology unit for recurrent headaches of one-year duration, vomiting of 2 months duration, and an episode of generalized tonic-clonic seizures, 2 weeks prior to presentation...
2023: Case Reports in Endocrinology
https://read.qxmd.com/read/38043965/benign-paroxysmal-vertigo-of-childhood
#37
REVIEW
Joshua Gurberg, Kinga K Tomczak, Jacob R Brodsky
Benign paroxysmal vertigo of childhood (or recurrent vertigo of childhood) is the most common cause of vertigo in young children. It is considered a pediatric migraine variant or precursor disorder, and children with the condition have an increased likelihood of developing migraine later in life than the general population. Episodes are typically associated with room-spinning vertigo in conjunction with other migrainous symptoms (e.g. pallor, nausea, etc.), but it is rarely associated with headaches. Episodes typically only last for a few minutes and occur with a frequency of days to weeks without interictal symptoms or exam/test abnormalities...
2023: Handbook of Clinical Neurology
https://read.qxmd.com/read/38043964/alternating-hemiplegia-of-childhood
#38
REVIEW
Piriyankan Ananthavarathan, Salwa Kamourieh
Alternating hemiplegia of childhood (AHC) is characterized by recurrent episodes of hemiplegia which may alternate sides between attacks. The condition is associated with severe neurodevelopmental disorder presenting in early infancy, and may encompass a wide range of other paroxysmal manifestations (e.g., dystonia, nystagmus, dysautonomia) and pervasive neurological disabilities (e.g., developmental delay, learning disabilities, choreoathetosis, and ataxia). Epileptic seizures are particularly common among patients with AHC...
2023: Handbook of Clinical Neurology
https://read.qxmd.com/read/38043963/abdominal-migraine-and-cyclical-vomiting-syndrome
#39
REVIEW
Sanjay Cheema, Manjit Matharu
Abdominal migraine and cyclical vomiting syndrome (CVS) are characteristic syndromes which have overlapping characteristics with migraine but lack the cardinal symptom of headache. Both abdominal migraine and CVS are characterized by recurrent attacks of nausea, vomiting, and/or abdominal pain lasting hours to a few days, with symptom freedom between attacks. Both abdominal migraine and CVS typically occur in children and adolescents, who often go on to develop more typical migraine headaches when older, but may also present for the first time in adults...
2023: Handbook of Clinical Neurology
https://read.qxmd.com/read/38029778/word-finding-difficulties-as-a-prominent-early-finding-in-a-later-diagnosis-of-attention-deficit-hyperactivity-disorder
#40
JOURNAL ARTICLE
Esther Ganelin-Cohen, Tammy Pilowsky Peleg, Noa Leibovich, Esther Bachrachg, Nathan Watemberg
OBJECTIVE:  Attention deficit hyperactivity disorder (ADHD) is a common neuropsychological disorder primarily diagnosed in childhood. Early intervention was found to significantly improve developmental outcomes, implicating on the role of early identification of ADHD markers. In the current study, we explored the developmental history of children referred to neurological assessment to identify early ADHD predictors. METHODS:  A total of 92 children and adolescents (41 females) recruited at a pediatric neurology clinic, with suspected ADHD ( n  = 39) or other neurological difficulties ( n  = 53) such as headaches, seizures, tic disorders, orthostatic hypotension, postischemic stroke, intermittent pain, and vasovagal syncope...
November 29, 2023: Neuropediatrics
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