keyword
MENU ▼
Read by QxMD icon Read
search

Pregnancy associated breast cancer

keyword
https://www.readbyqxmd.com/read/29346474/examining-non-participation-to-the-maternal-follow-up-within-the-danish-national-birth-cohort
#1
Mette Bliddal, Zeyan Liew, Anton Pottegård, Helene Kirkegaard, Jørn Olsen, Ellen A Nohr
A follow-up questionnaire on maternal health has been distributed within the Danish National Birth Cohort (established 1996-2002) 14 years after the index birth. Answers were obtained for 41,466 of 78,010 (53.2%) eligible mothers. To ensure the appropriate use of these data, the possibility of selection bias due to non-participation must be evaluated. We estimated four selected exposure-outcome associations (pre-pregnancy weight - depression; exercise - degenerative musculoskeletal conditions; smoking - heart disease; and alcohol consumption - breast cancer)...
January 16, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29344741/assessment-of-potential-risk-factors-for-breast-cancer-in-a-population-in-southern-brazil
#2
Juliana Zeni Breyer, Eliana Marcia Wendland, Natália Luiza Kops, Maira Caleffi, Luciano Serpa Hammes
PURPOSE: The aim of this study is to assess potential risk factors for breast cancer in a population in Southern Brazil and build a multivariate logistic model using these factors for breast cancer risk prediction. METHODS: A total of 4242 women between 40 and 69 years of age without a history of breast cancer were selected at primary healthcare facilities in Porto Alegre and submitted to mammographic screening. They were evaluated for potential risk factors. RESULTS: In all, 73 participants among the 4242 women had a breast cancer diagnosis during the follow-up of the project (10 years)...
January 17, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29338058/menstrual-and-reproductive-factors-and-risk-of-breast-cancer-a-case-control-study-in-the-fez-region-morocco
#3
Mohamed Khalis, Barbara Charbotel, Véronique Chajès, Sabina Rinaldi, Aurélie Moskal, Carine Biessy, Laure Dossus, Inge Huybrechts, Emmanuel Fort, Nawfel Mellas, Samira Elfakir, Hafida Charaka, Chakib Nejjari, Isabelle Romieu, Karima El Rhazi
BACKGROUND: Breast cancer is the most common cancer in women worldwide. In the Moroccan context, the role of well-known reproductive factors in breast cancer remains poorly documented. The aim of this study was to explore the relationship between menstrual and reproductive factors and breast cancer risk in Moroccan women in the Fez region. METHODS: A case-control study was conducted at the Hassan II University Hospital of Fez between January 2014 and April 2015...
2018: PloS One
https://www.readbyqxmd.com/read/29330856/reproductive-history-breast-feeding-and-risk-of-triple-negative-breast-cancer-the-breast-cancer-etiology-in-minorities-bem-study
#4
Esther M John, Lisa M Hines, Amanda I Phipps, Jocelyn Koo, Teri A Longacre, Sue A Ingles, Kathy B Baumgartner, Martha L Slattery, Anna H Wu
Few risk factors have been identified for triple negative breast cancer (TNBC) which lacks expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). This more aggressive subtype disproportionately affects some racial/ethnic minorities and is associated with lower survival. We pooled data from three population-based studies (558 TNBC and 5,111 controls) and examined associations of TNBC risk with reproductive history and breast-feeding. We estimated odds ratios (OR) and 95% confidence intervals (CI) using multivariable logistic regression...
January 13, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29327596/fertility-preservation-in-brca-mutated-women-when-and-how
#5
Michaël Grynberg, Jade Raad, Marjorie Comtet, Claire Vinolas, Isabelle Cédrin-Durnerin, Charlotte Sonigo
BRCA 1 and 2 genes play a critical role in the safeguarding of DNA integrity. It is now well established that BRCA1 and BRCA2-mutated women are at increased risk of breast and ovarian cancers. However, several lines of evidence indicate that this genetic status may also be associated with ovarian dysfunction, in particular a reduced ovarian reserve. Considering the gonadal toxicity of cancer treatments and the recommendation of prophylactic bilateral salpingo-oophorectomy around 40 years, young BRCA mutation carriers are confronted with difficult family planning decisions...
January 12, 2018: Future Oncology
https://www.readbyqxmd.com/read/29327114/anthropometric-characteristics-and-ovarian-cancer-risk-and-survival
#6
Albina N Minlikeeva, Kirsten B Moysich, Paul C Mayor, John L Etter, Rikki A Cannioto, Roberta B Ness, Kristen Starbuck, Robert P Edwards, Brahm H Segal, Sashikant Lele, Kunle Odunsi, Brenda Diergaarde, Francesmary Modugno
PURPOSE: Multiple studies have examined the role of anthropometric characteristics in ovarian cancer risk and survival; however, their results have been conflicting. We investigated the associations between weight change, height and height change and risk and outcome of ovarian cancer using data from a large population-based case-control study. METHODS: Data from 699 ovarian cancer cases and 1,802 controls who participated in the HOPE study were included. We used unconditional logistic regression adjusted for age, race, number of pregnancies, use of oral contraceptives, and family history of breast or ovarian cancer to examine the associations between self-reported height and weight and height change with ovarian cancer risk...
January 11, 2018: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/29317254/revisiting-progesterone-receptor-pr-actions-in-breast-cancer-insights-into-pr-repressive-functions
#7
Cecilia J Proietti, Mauro E Cenciarini, Patricia V Elizalde
Progesterone receptor (PR) is a master regulator in female reproductive tissues that controls developmental processes and proliferation and differentiation during the reproductive cycle and pregnancy. PR also plays a role in progression of endocrine-dependent breast cancer. As a member of the nuclear receptor family of ligand-dependent transcription factors, the main action of PR is to regulate networks of target gene expression in response to binding its cognate steroid hormone, progesterone. Liganded-PR transcriptional activation has been thoroughly studied and associated mechanisms have been described while progesterone-mediated repression has remained less explored...
January 6, 2018: Steroids
https://www.readbyqxmd.com/read/29302853/progesterone-receptor-pgr-gene-variants-associated-with-breast-cancer-and-associated-features-a-case-control-study
#8
Rabeb M Ghali, Maryam A Al-Mutawa, Bashayer H Ebrahim, Hanen H Jrah, Sonia Zaied, Hanen Bhiri, Fahmi Hmila, Touhami Mahjoub, Wassim Y Almawi
Insofar as altered estrogen receptor-progesterone receptor (PR) expression contribute to breast cancer pathogenesis, previous studies examined the association of genetic variation in PR gene (PGR) with breast cancer, but with mixed outcome. We evaluated the association between PGR variants, and breast cancer and associated features. A retrospective case-control study involving 183 female breast cancer patients, and 222 control women. PGR genotyping was done by real-time PCR. Minor allele frequencies of rs1042838, rs590688, and rs10895068 PGR gene polymorphisms were significantly higher in breast cancer patients compared to controls...
January 4, 2018: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/29285226/parity-improves-anti-tumor-immunity-in-breast-cancer-patients
#9
Anna-Lena Krause, Florian Schuetz, Marc Boudewijns, Maria Pritsch, Markus Wallwiener, Michael Golatta, Joachim Rom, Joerg Heil, Christof Sohn, Andreas Schneeweiss, Philipp Beckhove, Christoph Domschke
Compared to nulliparous women, parous women have an up to 50% lower lifetime risk of developing breast cancer. An endogenous mechanism to prevent the development of cancer is the destruction of tumor cells by T cells that recognize tumor-associated antigens (TAA). Since a number of TAA are also highly present in the breast and placenta of pregnant women, we investigated the induction and characteristics of spontaneous T cell responses against TAA during pregnancy. To this end, we collected peripheral blood from healthy nulliparous, primigravid and parous women, as well as from breast cancer patients...
December 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/29235933/faster-ticking-rate-of-the-epigenetic-clock-is-associated-with-faster-pubertal-development-in-girls
#10
Alexandra M Binder, Camila Corvalan, Verónica Mericq, Ana Pereira, José Luis Santos, Steve Horvath, John Shepherd, Karin B Michels
Epigenetic age is an indicator of biological aging, capturing the impact of environmental and behavioral influences across time on cellular function. Deviance between epigenetic age and chronological age (AgeAccel) is a predictor of health. Pubertal timing has similarly been associated with cancer risk and mortality rate among females. We examined the association between AgeAccel and pubertal timing and adolescent breast composition in the longitudinal Growth and Obesity Cohort Study. AgeAccel was estimated in whole blood using the Horvath method at breast Tanner 2 (B2) and 4 (B4)...
December 13, 2017: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/29218120/characteristics-and-correlates-of-woman-eligible-for-targeted-screening-mammography-in-oman
#11
Mahmood Masud Al Awfi, Obaid Said Al-Hubaishi
Objectives: We sought to determine the characteristics of women eligible for a high-yield screening mammography program in Oman. Methods: We conducted a retrospective review of women who underwent breast cancer screening at the Oman Cancer Association from 22 December 2009 to 6 February 2011. Women with a Breast Imaging Reporting and Data System (BI-RADS) score of 4-5 were compared with those with a score of 1-3 based on well-known breast cancer risk factors using the case-control approach analysis...
November 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/29198302/obstructive-sleep-apnea-in-gestational-diabetes-a-pilot-study-of-the-role-of-the-hypothalamic-pituitary-adrenal-axis
#12
Margaret H Bublitz, Joao Filipe Monteiro, Andrew Caraganis, Susan Martin, Jeffrey Parker, Lucia Larson, Margaret A Miller, Ghada Bourjeily
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) in pregnancy is associated with gestational diabetes mellitus (GDM). This propensity toward heightened insulin resistance in OSA patients has not been well characterized and may be related to dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. The aim of this study was to (1) assess the prevalence of OSA in pregnant women with GDM, (2) evaluate whether HPA axis dysregulation relates to OSA, and (3) investigate the relation between insulin resistance and OSA...
November 29, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29197068/drivers-of-advanced-stage-at-breast-cancer-diagnosis-in-the-multi-country-african-breast-cancer-disparities-in-outcomes-abc-do-study
#13
Fiona McKenzie, Annelle Zietsman, Moses Galukande, Angelica Anele, Charles Adisa, Groesbeck Parham, Leeya Pinder, Herbert Cubasch, Maureen Joffe, Frederick Kidaaga, Robert Lukande, Awa U Offiah, Ralph O Egejuru, Aaron Shibemba, Joachim Schuz, Benjamin O Anderson, Isabel Dos Santos Silva, Valerie McCormack
Breast cancer (BC) survival rates in sub-Saharan Africa (SSA) are low in part due to advanced stage at diagnosis. As one component of a study of the entire journey of SSA women with BC, we aimed to identify shared and setting-specific drivers of advanced stage BC. Women newly diagnosed in the multi-country African Breast Cancer - Disparities in Outcomes (ABC-DO) study completed a baseline interview and their stage information was extracted from medical records. Ordinal logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI) for advanced stage (I, II, III, IV) in relation to individual woman-level, referral and biological factors...
December 2, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29193311/proteomics-analysis-of-human-breast-milk-to-assess-breast-cancer-risk
#14
Roshanak Aslebagh, Devika Channaveerappa, Kathleen F Arcaro, Costel C Darie
Detection of breast cancer (BC) in young women is challenging because mammography, the most common tool for detecting BC, is not effective on the dense breast tissue characteristic of young women. In addition to the limited means for detecting their BC, young women face a transient increased risk of pregnancy-associated BC. As a consequence, reproductively active women could benefit significantly from a tool that provides them with accurate risk assessment and early detection of BC. One potential method for detection of BC is biochemical monitoring of proteins and other molecules in bodily fluids such as serum, nipple aspirate, ductal lavage, tear, urine, saliva and breast milk...
November 29, 2017: Electrophoresis
https://www.readbyqxmd.com/read/29168177/tumor-characteristics-and-prognosis-in-women-with-pregnancy-associated-breast-cancer
#15
Anna L V Johansson, Therese M-L Andersson, Chung-Cheng Hsieh, Karin Jirström, Sven Cnattingius, Irma Fredriksson, Paul W Dickman, Mats Lambe
There is evidence of poor prognosis in women with pregnancy-associated breast cancer (PABC) diagnosed during pregnancy or within two years of delivery. Using a large, population-based cohort, we examined clinicopathologic features and survival in women with PABC. A cohort of women diagnosed with invasive breast cancer between 1992 and 2009 at ages 15 to 44 years was identified in the Swedish Cancer Register and the Breast Cancer Quality Registers. Dates of childbirths for each woman were retrieved from the Swedish Multi-Generation Register...
November 23, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29162041/does-anthracycline-based-chemotherapy-in-pregnant-women-with-cancer-offer-safe-cardiac-and-neurodevelopmental-outcomes-for-the-developing-fetus
#16
Marialuisa Framarino-Dei-Malatesta, Paolo Sammartino, Angela Napoli
BACKGROUND: Cancer treatment during pregnancy is a growing problem especially now that women delay childbearing. Systemic treatment of these malignancies during pregnancy centers mainly on the anticancer drugs anthracyclines, widely used in treating hematological and breast cancer during pregnancy and sometimes associated with early and late toxicity for the fetus. Owing to concern about their cardiac and neurodevelopmental toxicity more information is needed on which anthracycline to prefer and whether they can safely guarantee a cardiotoxicity-free outcome in the fetus...
November 21, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29139276/preventing-stroke-and-assessing-risk-in-women
#17
Tracey Keteepe-Arachi, Sanjay Sharma
Ischaemic stroke is rare in premenopausal women but risk increases with advancing age and doubles in the ten years following the menopause. Up to the age of 75 years men have a 25% higher risk of suffering a stroke compared with women. However, the increased life expectancy of women ultimately results in a higher overall incidence. Twice as many women die from stroke compare with breast cancer. Women with cerebrovascular disease are more likely to present with atypical symptoms than men. Altered mental status (including unresponsiveness, confusion and behavioural change) is the most common nonconventional symptom, and is reported by 23% of women compared with 15% of men...
March 2017: Practitioner
https://www.readbyqxmd.com/read/29116004/reproductive-profiles-and-risk-of-breast-cancer-subtypes-a-multi-center-case-only-study
#18
Olivier Brouckaert, Anja Rudolph, Annouschka Laenen, Renske Keeman, Manjeet K Bolla, Qin Wang, Adelheid Soubry, Hans Wildiers, Irene L Andrulis, Volker Arndt, Matthias W Beckmann, Javier Benitez, Carl Blomqvist, Stig E Bojesen, Hiltrud Brauch, Paul Brennan, Hermann Brenner, Georgia Chenevix-Trench, Ji-Yeob Choi, Sten Cornelissen, Fergus J Couch, Angela Cox, Simon S Cross, Kamila Czene, Mikael Eriksson, Peter A Fasching, Jonine Figueroa, Henrik Flyger, Graham G Giles, Anna González-Neira, Pascal Guénel, Per Hall, Antoinette Hollestelle, John L Hopper, Hidemi Ito, Michael Jones, Daehee Kang, Julia A Knight, Veli-Matti Kosma, Jingmei Li, Annika Lindblom, Jenna Lilyquist, Artitaya Lophatananon, Arto Mannermaa, Siranoush Manoukian, Sara Margolin, Keitaro Matsuo, Kenneth Muir, Heli Nevanlinna, Paolo Peterlongo, Katri Pylkäs, Suleeporn Saajrang, Caroline Seynaeve, Chen-Yang Shen, Xiao-Ou Shu, Melissa C Southey, Anthony Swerdlow, Soo-Hwang Teo, Rob A E M Tollenaar, Thérèse Truong, Chiu-Chen Tseng, Alexandra J van den Broek, Carolien H M van Deurzen, Robert Winqvist, Anna H Wu, Cheng Har Yip, Jyh-Cherng Yu, Wei Zheng, Roger L Milne, Paul D P Pharoah, Douglas F Easton, Marjanka K Schmidt, Montserrat Garcia-Closas, Jenny Chang-Claude, Diether Lambrechts, Patrick Neven
BACKGROUND: Previous studies have shown that reproductive factors are differentially associated with breast cancer (BC) risk by subtypes. The aim of this study was to investigate associations between reproductive factors and BC subtypes, and whether these vary by age at diagnosis. METHODS: We used pooled data on tumor markers (estrogen and progesterone receptor, human epidermal growth factor receptor-2 (HER2)) and reproductive risk factors (parity, age at first full-time pregnancy (FFTP) and age at menarche) from 28,095 patients with invasive BC from 34 studies participating in the Breast Cancer Association Consortium (BCAC)...
November 7, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/29111858/women-s-health-endocrine-update
#19
Ekta Kapoor, Stephanie Faubion, Stephanie Hines, Cynthia A Stuenkel
The clinical update serves as a brief review of recently published, high-impact, and potentially practice changing journal articles summarized for our readers. Topics include menopause, sexual dysfunction, breast health, contraception, osteoporosis, and cardiovascular disease. In this clinical update, we selected four recent high-impact publications related to endocrine issues in women. We have chosen to highlight research on subclinical hypothyroidism during pregnancy and adverse pregnancy outcomes, including cognitive outcomes in offspring; the progression of metabolic syndrome severity during the menopausal transition; and the association of diabetes and metformin use with cancer risk and mortality...
November 7, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/29111146/medical-contraindications-to-estrogen-and-contraceptive-use-among-women-veterans
#20
Colleen P Judge, Xinhua Zhao, Florentina E Sileanu, Maria K Mor, Sonya Borrero
BACKGROUND: Women veterans have high rates of medical comorbidities and may be particularly vulnerable to adverse health outcomes associated with unintended pregnancy. OBJECTIVES: The objective of the study was to estimate the prevalence of medical contraindications to estrogen-containing combined hormonal contraception among women veterans of reproductive age and to evaluate the relationship between contraindications and contraceptive use. STUDY DESIGN: This was a secondary analysis of data from a cross-sectional, telephone-based survey with a national sample of 2302 female veterans, aged 18-45 years, who use the Veterans Administration Healthcare System for primary care...
October 27, 2017: American Journal of Obstetrics and Gynecology
keyword
keyword
4662
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"