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Lupus nefritis

L V Zhdanova, L I Patrushev, V V Dolgikh, A B-Zh Bimbaev, O Ch Khoĭkova
BACKGROUND: The article is devoted to the study of clinical and laboratory characteristics of the current of hemorrhagic vasculitis in children in the Republic of Buryatia. PATIENTS AND METHODS: The study included 27 patients aged 7.6 +/- 4.02 years, who conducted clinical and laboratory tests, immunological study of antiphospholipids of antibodies, genetic testing for thrombophilia markers of candidate genes. RESULTS: The results showed that hemorrhagic vasculitis often affects children of Buryat nationality...
2014: Vestnik Rossiĭskoĭ Akademii Meditsinskikh Nauk
Dejan Celić, Tatjana Ilić, Tatjana Durdević-Mirković, Igor Mitić, Biljana Milić, Slobodan Curić
INTRODUCTION: Mycophenolate mofetil is an immunosupressive agent used in transplantation and subsequently in a variety of autoimmune conditions. It inhibits both B and T lymphocyte proliferation, and also has nonimmune effects on the kidney. The major experience in systemic lupus erythematosus has focused on proliferative lupus nephritis. MATERIALS AND METHODS: In our study we treated 8 female patients with proliferative lupus nefritis with combination therapy of prednisone (1 mg/kg body weight) and mycophenolate mofetil (2 g per day)...
2007: Medicinski Pregled
J M Nieto, C Alvarez, J M Flores, J Romano
A morphological and morphometrical study has been carried out on glomerular lesions in mink with spontaneous Aleutian disease, using the WHO classification for Systemic Lupus Erytematous Nefritis. 154 renal samples from sick animals and 10 samples from uninfected mink were processed by routine histopathological techniques and metacrylate inclusions. The samples were studied quantitatively with an automatic image analyzer. 5 forms of glomerulonephritis (GN) were identified: mesangial glomerulonephritis (n = 13), focal and segmental GN (n = 10), diffuse GN (n = 99), membranous GN (n = 12) and advanced sclerosing GN (n = 10) and were associated with the degree of interstitial plasmocytosis...
April 1991: Histology and Histopathology
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