keyword
MENU ▼
Read by QxMD icon Read
search

PVR

keyword
https://www.readbyqxmd.com/read/28930838/clinical-efficacy-of-intravesical-electrical-stimulation-on-detrusor-underactivity-8-years-of-experience-from-a-single-center
#1
Han Deng, Limin Liao, Juan Wu, Guoqing Chen, Xing Li, Zhaoxia Wang, Li Wan
The aim of this study was to retrospectively evaluate the effectiveness of intravesical electrical stimulation (IVES) on detrusor underactivity (DU).From 2009 to 2016, a total of 105 patients with symptoms of DU who were treated with IVES were included in this retrospective study. The medical records, physical examination findings, urine culture results, and video-urodynamic studies were reviewed. Changes in post-void residual urine (PVR) and voiding efficiency (VE) were included for evaluation of efficacy...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28929090/echocardiographic-assessment-of-pulmonary-arterial-hypertension-for-pediatricians-and-neonatologists
#2
REVIEW
Gregory James Skinner
There is a growing awareness of the role that increased pulmonary vascular resistance (PVR) plays in many pathologies; therefore, assessment of pulmonary artery pressure (PAP) is an increasingly requested investigation in the critical care environment. This article will go through the basic concepts regarding PAP and PVR, then will go on to outline the various echocardiographic parameters which are used to assess them. Finally, an outline of how to undertake this assessment will be presented.
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28919201/macitentan-for-the-treatment-of-inoperable-chronic-thromboembolic-pulmonary-hypertension-merit-1-results-from-the-multicentre-phase-2-randomised-double-blind-placebo-controlled-study
#3
Hossein-Ardeschir Ghofrani, Gérald Simonneau, Andrea M D'Armini, Peter Fedullo, Luke S Howard, Xavier Jaïs, David P Jenkins, Zhi-Cheng Jing, Michael M Madani, Nicolas Martin, Eckhard Mayer, Kelly Papadakis, Dominik Richard, Nick H Kim
BACKGROUND: Macitentan is beneficial for long-term treatment of pulmonary arterial hypertension. The microvasculopathy of chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension are similar. METHODS: The phase 2, double-blind, randomised, placebo-controlled MERIT-1 trial assessed macitentan in 80 patients with CTEPH adjudicated as inoperable. Patients identified as WHO functional class II-IV with a pulmonary vascular resistance (PVR) of at least 400 dyn·s/cm(5) and a walk distance of 150-450 m in 6 min were randomly assigned (1:1), via an interactive voice/web response system, to receive oral macitentan (10 mg once a day) or placebo...
September 8, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28915226/pulmonary-vascular-function-and-aerobic-exercise-capacity-at-moderate-altitude
#4
Vitalie Faoro, Gael Deboeck, Marco Vicenzi, Anne-Fleur Gaston, Bamodi Simaga, Grégory Doucende, Ilona Hapkova, Emma Roca, Enric Subirats, Fabienne Durand, Robert Naeije
PURPOSE: There has been suggestion that a greater "pulmonary vascular reserve" defined by a low pulmonary vascular resistance (PVR) and a high lung diffusing capacity (DL) allow for a superior aerobic exercise capacity. How pulmonary vascular reserve might affect exercise capacity at moderate altitude is not known. METHODS: Thirty-eight healthy subjects underwent an exercise stress echocardiography of the pulmonary circulation, combined with measurements of DL for nitric oxide (NO) and carbon monoxide (CO) and a cardiopulmonary exercise test at sea level and at an altitude of 2250 m...
October 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28914701/elevated-postvoid-residual-urine-volume-identifying-risk-factors-and-predicting-resolution-in-women-with-pelvic-organ-prolapse
#5
Amanda Ulrich, Patricia Davis, Paul Tulikangas, David M OʼSullivan, Katie Propst
OBJECTIVES: This study aims to identify risk factors for elevated preoperative postvoid residual (PVR) and persistently elevated postoperative PVR and to evaluate the resolution rate of elevated PVR urine volume in patients undergoing reconstructive surgery for pelvic organ prolapse (POP). METHODS: This was a retrospective cohort study comparing 50 women with elevated preoperative PVR (≥100 mL) and 50 women with normal PVR (<100 mL). Preoperative demographic, physical examination, urodynamic data, type of surgery performed, and postoperative trial of void data were collected...
September 13, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28913545/periostin-in-vitreoretinal-diseases
#6
REVIEW
Shigeo Yoshida, Takahito Nakama, Keijiro Ishikawa, Shintaro Nakao, Koh-Hei Sonoda, Tatsuro Ishibashi
Proliferative vitreoretinal diseases such as diabetic retinopathy, proliferative vitreoretinopathy (PVR), and age-related macular degeneration are a leading cause of decreased vision and blindness in developed countries. In these diseases, retinal fibro(vascular) membrane (FVM) formation above and beneath the retina plays an important role. Gene expression profiling of human FVMs revealed significant upregulation of periostin. Subsequent analyses demonstrated increased periostin expression in the vitreous of patients with both proliferative diabetic retinopathy and PVR...
September 14, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28906008/role-of-macrophage-migration-inhibitory-factor-mif-in-the-effects-of-oxidative-stress-on-human-retinal-pigment-epithelial-cells
#7
Ji-Ae Ko, Yasuyuki Sotani, Diah Gemala Ibrahim, Yoshiaki Kiuchi
Proliferative vitreoretinopathy (PVR) is the major cause of treatment failure in individuals who undergo surgery for retinal detachment. The epithelial-mesenchymal transition (EMT) in retinal pigment epithelium (RPE) cells contributes to the pathogenesis of PVR. Oxidative stress is thought to play a role in the progression of retinal diseases including PVR. We have now examined the effects of oxidative stress on the EMT and related processes in the human RPE cell line. We found that H2 O2 induced the contraction of RPE cells in a three-dimensional collagen gel...
September 14, 2017: Cell Biochemistry and Function
https://www.readbyqxmd.com/read/28895627/-vitreous-substitute-in-retinal-detachment-surgery-why-we-need-a-new-tamponade-strategy
#8
Peter Szurman
Pars plana vitrectomy combined with an endotamponade is the most important concept in retinal detachment surgery. Numerous advances in techniques and tamponade materials have been made, but the general problems of retinal detachment surgery are still unsolved: The primary success rate is not adequate, and there is no adequate strategy to address proliferative vitreoretinopathy, multiple retinal breaks or persistent hypotony. The story of tamponades is full of myths and misunderstandings. A critical review shows that tamponades have only a minor role in the history of retinal detachment surgery...
September 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28895275/incidence-and-outcome-of-infective-endocarditis-following-percutaneous-versus-surgical-pulmonary-valve-replacement
#9
Gentian Lluri, Daniel S Levi, Emily Miller, Abbie Hageman, Sanjay Sinha, Soraya Sadeghi, Brian Reemtsen, Hillel Laks, Reshma Biniwale, Morris Salem, Gregory A Fishbein, Jamil Aboulhosn
OBJECTIVES: To provide a comparison of the outcome of infective endocarditis (IE) in patients undergoing transcatheter pulmonary valve replacement (TPVR) versus surgical pulmonary valve replacement (SPVR). BACKGROUND: Although TPVR is thought to be associated with a higher risk of IE than SPVR, there is paucity of data to support this. METHODS: Patients who underwent TPVR or SPVR at UCLA between October 2010 and September 2016 were included and retrospectively analyzed...
September 12, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28893516/interleukin-6-is-independently-associated-with-right-ventricular-function-in-pulmonary-arterial-hypertension
#10
Kurt W Prins, Stephen L Archer, Marc Pritzker, Lauren Rose, E Kenneth Weir, Alok Sharma, Thenappan Thenappan
BACKGROUND: An elevated serum level of interleukin-6 (IL-6) in pulmonary arterial hypertension (PAH) patients results in a greater symptom burden and increased mortality; however, the mechanisms underlying these observations remain unclear. Because both pre-clinical and clinical data associate elevated IL-6 levels with impaired cardiac function, we hypothesized that the adverse effects of IL-6 in PAH result, in part, from right ventricular (RV) dysfunction. METHODS: We analyzed the relationship between IL-6 and RV function in 40 patients with PAH identified in our institutional PAH registry...
September 1, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28880160/pvr-patch-to-volume-reconstruction-for-large-area-motion-correction-of-fetal-mri
#11
Amir Alansary, Martin Rajchl, Steven G McDonagh, Maria Murgasova, Mellisa Damodaram, David F A Lloyd, Alice Davidson, Mary Rutherford, Joseph V Hajnal, Daniel Rueckert, Bernhard Kainz
In this paper we present a novel method for the correction of motion artifacts that are present in fetal Magnetic Resonance Imaging (MRI) scans of the whole uterus. Contrary to current slice-to-volume registration (SVR) methods, requiring an inflexible anatomical enclosure of a single investigated organ, the proposed patch-to-volume reconstruction (PVR) approach is able to reconstruct a large field of view of non-rigidly deforming structures. It relaxes rigid motion assumptions by introducing a specific amount of redundant information that is exploited with parallelized patch-wise optimization, super-resolution, and automatic outlier rejection...
September 1, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28878690/regulation-of-pulmonary-vascular-smooth-muscle-contractility-in-pulmonary-arterial-hypertension-implications-for-therapy
#12
REVIEW
Melissa A Lyle, Jonathan P Davis, Frank V Brozovich
There are two primary components that produce pulmonary arterial hypertension (PAH); aberrant structural changes (smooth muscle cell proliferation, smooth muscle cell hypertrophy, and the deposition of matrix proteins within the media of pulmonary arterial vessels), and excess vasoconstriction. However, in PAH, the target and aim of all current therapeutic agents is to reduce the contractility of the pulmonary vasculature; prostaglandins, phosphodiesterase inhibitors, guanylate cyclase stimulators, endothelin antagonists, NO inhalation and Rho kinase inhibitors all influence signaling pathways in the pulmonary vascular smooth muscle to decrease vasoconstriction, and hence, pulmonary vascular resistance (PVR)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28877445/anti-fibrosis-effect-of-nanoparticle-mediated-delivery-of-plasminogen-kringle-5
#13
Yi Lu, Weizhong Gu, Yanhong Ren, Jia Feng, Lili Yang, Ji Jin
Retinal fibrosis, including epiretinal membrane (ERM) and proliferative vitreoretinopathy (PVR), is an ocular disease that can lead to blindness. An efficacious therapy remains an unmet medical challenge. In this study, we intended to explore the inhibitory effects of the nanoparticle-mediated delivery of plasminogen kringle 5 (K5-NPs) on laser-induced ERM and to identify the potential anti-fibrosis targets of K5-NPs. A rat model of laser-induced ERM was used. Control-NPs or K5-NPs were intravitreally injected...
June 2017: Discovery Medicine
https://www.readbyqxmd.com/read/28875955/efficacy-of-real-world-entecavir-therapy-in-treatment-na%C3%A3-ve-chronic-hepatitis-b-patients
#14
Yan-Di Xie, Hui Ma, Bo Feng, Lai Wei
Background: Entecavir (ETV) has been shown to be effective in randomized controlled trials in highly selected patients with hepatitis B virus (HBV) infection. This study aimed to evaluate the efficacy of ETV in chronic hepatitis B (CHB) patients in the real-world setting. Methods: A total of 233 treatment-naïve, CHB patients who received at least 12 months of ETV treatment were included in this retrospective study. Rates of virological response (VR), hepatitis B s antigen (HBsAg) loss, hepatitis B e antigen (HBeAg) clearance/seroconversion, virological breakthrough, cirrhosis, and hepatocellular carcinoma were evaluated...
September 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28874810/innate-immune-activating-ligand-sumoylation-affects-tumor-cell-recognition-by-nk-cells
#15
Beatrice Zitti, Rosa Molfetta, Cinzia Fionda, Linda Quatrini, Helena Stabile, Mario Lecce, Valeria de Turris, Maria Rosaria Ricciardi, Maria Teresa Petrucci, Marco Cippitelli, Angela Gismondi, Angela Santoni, Rossella Paolini
Natural Killer cells are innate lymphocytes involved in tumor immunosurveillance. They express activating receptors able to recognize self-molecules poorly expressed on healthy cells but up-regulated upon stress conditions, including transformation. Regulation of ligand expression in tumor cells mainly relays on transcriptional mechanisms, while the involvement of ubiquitin or ubiquitin-like modifiers remains largely unexplored. Here, we focused on the SUMO pathway and demonstrated that the ligand of DNAM1 activating receptor, PVR, undergoes SUMOylation in multiple myeloma...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28871337/clinical-course-of-partial-virologic-response-with-prolonged-tenofovir-therapy-in-nuclos-t-ides-na%C3%A3-ve-patients-with-chronic-hepatitis-b
#16
In Du Jeong, Seok Won Jung, Bo Ryung Park, Byung Uk Lee, Jae Ho Park, Byung Gyu Kim, Sung-Jo Bang, Jung Woo Shin, Neung Hwa Park
BACKGROUND/AIMS: The clinical course of chronic hepatitis B (CHB) patients with partial virologic response (PVR) during tenofovir disoproxil fumarate (TDF) therapy remains unclear. METHODS: We retrospectively investigated the long-term clinical outcomes of TDF treatment in nucleos(t)ides-naïve CHB patients, particularly in those with PVR. RESULTS: A total of 391 patients treated with TDF therapy for more than 12 months were included. Virologic response (VR) was achieved in 341 patients (87...
September 4, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28870470/poliovirus-receptor-more-than-a-simple-viral-receptor
#17
REVIEW
Jonathan R Bowers, James M Readler, Priyanka Sharma, Katherine J D A Excoffon
The human poliovirus receptor (PVR) is a cell surface protein with a multitude of functions in human biology. PVR was initially identified as the receptor for the human poliovirus and recent discoveries have given a greater insight into both its morphology and its function. Alternative splicing of the PVR gene results in a total of 4 alternatively spliced isoforms. Two of these isoforms lack a complete transmembrane domain and are considered soluble and block viral infection; the remaining two transmembrane isoforms differ only at their extreme C-terminal domains resulting in differential localization in epithelia and polarity of viral infection...
September 7, 2017: Virus Research
https://www.readbyqxmd.com/read/28868600/a-pleural-vacuum-relief-device-for-pleural-drain-unit-use-in-the-hyperbaric-environment
#18
Marco Gelsomino, Theo Tsouras, Ian Millar, Andrew Fock
INTRODUCTION: When a standard water-seal pleural drain unit (PDU) is used under hyperbaric conditions there are scenarios where excessive negative intrapleural pressure (IPP) and/or fluid reflux can be induced, risking significant morbidity. We developed and tested a pleural vacuum relief (PVR) device which automatically manages these risks, whilst allowing more rapid hyperbaric pressure change rates. METHODS: The custom-made PVR device consists of a one-way pressure relief valve connected in line with a sterile micro filter selected for its specific flow capacity...
September 2017: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/28865107/effect-of-body-position-exercise-and-sedation-on-estimation-of-pulmonary-artery-pressure-in-dogs-with-degenerative-atrioventricular-valve-disease
#19
J D Rhinehart, K E Schober, B A Scansen, V Yildiz, J D Bonagura
BACKGROUND: Severity of pulmonary hypertension (PH) in dogs is related to clinical signs and prognosis. HYPOTHESIS/OBJECTIVES: We hypothesized that Doppler echocardiographic (DE) indices of pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR) are influenced by independent factors that create clinically important variability of DE-based estimates of PH in dogs. ANIMALS: Thirty-eight client owned dogs with naturally acquired degenerative atrioventricular valve disease and tricuspid regurgitation (TR)...
September 2, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28864340/clinical-and-patient-reported-outcomes-of-one-sided-anterior-urethroplasty-for-long-segment-or-panurethral-strictures
#20
Jeffrey Spencer, Stephen Blakely, Michael Daugherty, Javier C Angulo, Francisco Martins, Krishnan Venkatesan, Dmitriy Nikolavsky
OBJECTIVES: To evaluate clinical and patient-reported urinary and sexual outcomes after a long-segment stricture repair using the one-sided urethral dissection, penile invagination and dorsal BMG onlay technique described by Kulkarni. METHODS: Patients from four institutions after single-stage repairs for long-segment urethral strictures (> 8 cm) from January 2002 to April 2016 were reviewed. Technique described by Kulkarni et al was used in all cases. Clinical outcomes included uroflowmetry (Qmax), post-void residuals (PVR)...
August 29, 2017: Urology
keyword
keyword
46604
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"