keyword
MENU ▼
Read by QxMD icon Read
search

stent AND magnesium

keyword
https://www.readbyqxmd.com/read/27869217/magnesium-alloy-covered-stent-for-treatment-of-a-lateral-aneurysm-model-in-rabbit-common-carotid-artery-an-in-vivo-study
#1
Wu Wang, Yong-Li Wang, Mo Chen, Liang Chen, Jian Zhang, Yong-Dong Li, Ming-Hua Li, Guang-Yin Yuan
Magnesium alloy covered stents have rarely been used in the common carotid artery (CCA). We evaluated the long-term efficacy of magnesium alloy covered stents in a lateral aneurysm model in rabbit CCA. Magnesium alloy covered stents (group A, n = 7) or Willis covered stents (group B, n = 5) were inserted in 12 New Zealand White rabbits and they were followed up for 12 months. The long-term feasibility for aneurysm occlusion was studied through angiograms; the changes in vessel area and lumen area were assessed with IVUS...
November 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27785607/plastic-strains-during-stent-deployment-have-a-critical-influence-on-the-rate-of-corrosion-in-absorbable-magnesium-stents
#2
Emmet Galvin, Christy Cummins, Shoichiro Yoshihara, Bryan J Mac Donald, Caitríona Lally
Magnesium stents are a promising candidate in the emerging field of absorbable metallic stents (AMSs). In this study, the mechanical and corrosion performance of dog-bone specimens and a specific stent design of a magnesium alloy, WE43, are assessed experimentally in terms of their corrosion behaviour and mechanical integrity. It is shown that plastic strains that are induced in the struts of the stent during stent deployment have a critical influence in directing subsequent corrosion behaviour within the material...
October 26, 2016: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/27704201/technical-feasibility-and-tissue-reaction-after-silicone-covered-biodegradable-magnesium-stent-insertion-in-the-oesophagus-a-primary-study-in-vitro-and-in-vivo
#3
Yue-Qi Zhu, Laura Edmonds, Li-Ming Wei, Rei-La Zheng, Ruo-Yu Cheng, Wen-Guo Cui, Ying-Sheng Cheng
OBJECTIVES: Determine the feasibility of and tissue response to biodegradable magnesium-silicone stent insertion into the oesophagus of rabbits. METHODS: Mechanical compression-recovery and degradation behaviours of the stents were investigated in vitro. Thirty rabbits were randomly divided into a magnesium-silicone stent group (n = 15) that received stent insertion into the lower 1/3 of the oesophagus under fluoroscopic guidance and a control group (n = 15)...
October 4, 2016: European Radiology
https://www.readbyqxmd.com/read/27698548/bio-adaption-between-magnesium-alloy-stent-and-the-blood-vessel-a-review
#4
Jun Ma, Nan Zhao, Lexxus Betts, Donghui Zhu
Biodegradable magnesium (Mg) alloy stents are the most promising next generation of bio-absorbable stents. In this article, we summarized the progresses on the in vitro studies, animal testing and clinical trials of biodegradable Mg alloy stents in the past decades. These exciting findings led us to propose the importance of the concept "bio-adaption" between the Mg alloy stent and the local tissue microenvironment after implantation. The healing responses of stented blood vessel can be generally described in three overlapping phases: inflammation, granulation and remodeling...
September 2016: Journal of Materials Science & Technology
https://www.readbyqxmd.com/read/27612959/design-of-magnesium-alloys-with-controllable-degradation-for-biomedical-implants-from-bulk-to-surface
#5
Xia Li, Xiangmei Liu, Shuilin Wu, K W K Yeung, Yufeng Zheng, Paul K Chu
: The combination of high strength, light weight, and natural biodegradability renders magnesium (Mg)-based alloys promising in orthopedic implants and cardiovascular stents. Being metallic materials, Mg and Mg alloys made for scaffolds provide the necessary mechanical support for tissue healing and cell growth in the early stage, while natural degradation and reabsorption by surrounding tissues in the later stage make an unnecessarily follow-up removal surgery. However, uncontrolled degradation may collapse the scaffolds resulting in premature implant failure, and there has been much research in controlling the degradation rates of Mg alloys...
November 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27612743/proteomic-profile-of-mouse-fibroblasts-exposed-to-pure-magnesium-extract
#6
Zhen Zhen, Bérengère Luthringer, Li Yang, Tingfei Xi, Yufeng Zheng, Frank Feyerabend, Regine Willumeit, Chen Lai, Zigang Ge
Magnesium and its alloys gain wide attention as degradable biomaterials. In order to reveal the molecular mechanism of the influence of biodegradable magnesium on cells, proteomics analysis was performed in this work. After mouse fibroblasts (L929) were cultured with or without Mg degradation products (Mg-extract) for 8, 24, and 48h, changes in protein expression profiles were obtained using isobaric tags for relative and absolute quantitation (iTRAQ) coupled two dimensional liquid chromatography-tandem mass spectrometry (2D LC MS/MS)...
December 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27592325/freedom-solo-associated-thrombocytopaenia-is-valve-dependent-and-not-due-to-in-vitro-pseudothrombocytopaenia
#7
Olaf Stanger, Brigitta Gahl, Michael Grabherr, Richard Krausler, Sarah Longnus, Andreas Meinitzer, Janne Cadamuro
BACKGROUND: Use of the Freedom SOLO (FS) stentless aortic bioprosthesis is limited by a unique and as yet unexplained severe decrease in postoperative platelet count in the absence of FS-related excess bleeding or thromboembolism. We investigated whether anticoagulant-associated pseudothrombocytopaenia could explain this complication. METHODS: Thirty consecutive patients (mean age 75.4±7.7 years, 11 [36.7%] female) underwent elective aortic valve replacement (AVR) with either the stented bovine Mitroflow (MF, n=18) or the stentless bovine FS (n=12) aortic valve bioprostheses...
August 16, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27331417/enhanced-in-vitro-and-in-vivo-performance-of-mg-zn-y-nd-alloy-achieved-with-aptes-pretreatment-for-drug-eluting-vascular-stent-application
#8
Jing Liu, Bo Zheng, Pei Wang, Xingang Wang, Bin Zhang, Qiuping Shi, Tingfei Xi, Ming Chen, Shaokang Guan
Bioabsorbable magnesium alloys are becoming prominent as temporary functional implants, as they avoid the risks generated by permanent metallic implants such as persistent inflammation and late restenosis. Nevertheless, the overfast corrosion of Mg alloys under physiological conditions hinders their wider application as medical implant materials. Here we investigate a simple one-step process to introduce a cross-linked 3-amino-propyltrimethoxysilane (APTES) silane physical barrier layer on the surface of Mg-Zn-Y-Nd alloys prior to electrostatic spraying with rapamycin-eluting poly(lactic-co-glycolic acid) (PLGA) layer...
July 20, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27266902/in-vitro-performance-investigation-of-bioresorbable-scaffolds-standard-tests-for-vascular-stents-and-beyond
#9
Wolfram Schmidt, Peter Behrens, Christoph Brandt-Wunderlich, Stefan Siewert, Niels Grabow, Klaus-Peter Schmitz
BACKGROUND/PURPOSE: Biodegradable polymers are the main materials for coronary scaffolds. Magnesium has been investigated as a potential alternative and was successfully tested in human clinical trials. However, it is still challenging to achieve mechanical parameters comparative to permanent bare metal (BMS) and drug-eluting stents (DES). As such, in vitro tests are required to assess mechanical parameters correlated to the safety and efficacy of the device. METHODS/MATERIALS: In vitro bench tests evaluate scaffold profiles, length, deliverability, expansion behavior including acute elastic and time-dependent recoil, bending stiffness and radial strength...
September 2016: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/27094868/biodegradable-metals-for-cardiovascular-stents-from-clinical-concerns-to-recent-zn-alloys
#10
Patrick K Bowen, Emily R Shearier, Shan Zhao, Roger J Guillory, Feng Zhao, Jeremy Goldman, Jaroslaw W Drelich
Metallic stents are used to promote revascularization and maintain patency of plaqued or damaged arteries following balloon angioplasty. To mitigate the long-term side effects associated with corrosion-resistant stents (i.e., chronic inflammation and late stage thrombosis), a new generation of so-called "bioabsorbable" stents is currently being developed. The bioabsorbable coronary stents will corrode and be absorbed by the artery after completing their task as vascular scaffolding. Research spanning the last two decades has focused on biodegradable polymeric, iron-based, and magnesium-based stent materials...
May 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/27085049/biodegradable-elastomeric-coatings-with-controlled-anti-proliferative-agent-release-for-magnesium-based-cardiovascular-stents
#11
Xinzhu Gu, Zhongwei Mao, Sang-Ho Ye, Youngmi Koo, Yeoheung Yun, Tarannum R Tiasha, Vesselin Shanov, William R Wagner
Vascular stent design continues to evolve to further improve the efficacy and minimize the risks associated with these devices. Drug-eluting coatings have been widely adopted and, more recently, biodegradable stents have been the focus of extensive evaluation. In this report, biodegradable elastomeric polyurethanes were synthesized and applied as drug-eluting coatings for a relatively new class of degradable vascular stents based on Mg. The dynamic degradation behavior, hemocompatibility and drug release were investigated for poly(carbonate urethane) urea (PCUU) and poly(ester urethane) urea (PEUU) coated magnesium alloy (AZ31) stents...
August 1, 2016: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/27062241/novel-zn-based-alloys-for-biodegradable-stent-applications-design-development-and-in-vitro-degradation
#12
E Mostaed, M Sikora-Jasinska, A Mostaed, S Loffredo, A G Demir, B Previtali, D Mantovani, R Beanland, M Vedani
The search for a degradable metal simultaneously showing mechanical properties equal or higher to that of stainless steel and uniform degradation is still an open challenge. Several magnesium-based alloys have been studied, but their degradation rate has proved to be too fast and rarely homogeneous. Fe-based alloys show appropriate mechanical properties but very low degradation rate. In the present work, four novel Zn-Mg and two Zn-Al binary alloys were investigated as potential biodegradable materials for stent applications...
July 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27047673/opportunities-and-challenges-for-the-biodegradable-magnesium-alloys-as-next-generation-biomaterials
#13
REVIEW
Wenjiang Ding
In recent years, biodegradable magnesium alloys emerge as a new class of biomaterials for tissue engineering and medical devices. Deploying biodegradable magnesium-based materials not only avoids a second surgical intervention for implant removal but also circumvents the long-term foreign body effect of permanent implants. However, these materials are often subjected to an uncontrolled and fast degradation, acute toxic responses and rapid structural failure presumably due to a localized, too rapid corrosion process...
June 2016: Regenerative Biomaterials
https://www.readbyqxmd.com/read/26868826/bioresorbable-scaffolds-a-new-paradigm-in-percutaneous-coronary-intervention
#14
REVIEW
Erhan Tenekecioglu, Vasim Farooq, Christos V Bourantas, Rafael Cavalcante Silva, Yoshinobu Onuma, Mustafa Yılmaz, Patrick W Serruys
Numerous advances and innovative therapies have been introduced in interventional cardiology over the recent years, since the first introduction of balloon angioplasty, but bioresorbable scaffold is certainly one of the most exciting and attracting one. Despite the fact that the metallic drug-eluting stents have significantly diminished the re-stenosis ratio, they have considerable limitations including the hypersensitivity reaction to the polymer that can cause local inflammation, the risk of neo-atherosclerotic lesion formation which can lead to late stent failure as well as the fact that they may preclude surgical revascularization and distort vessel physiology...
2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/26860452/susceptibility-of-metallic-magnesium-implants-to-bacterial-biofilm-infections
#15
Muhammad Imran Rahim, Manfred Rohde, Bushra Rais, Jan-Marten Seitz, Peter P Mueller
Magnesium alloys have promising mechanical and biological properties as biodegradable medical implant materials for temporary applications during bone healing or as vascular stents. Whereas conventional implants are prone to colonization by treatment resistant microbial biofilms in which bacteria are embedded in a protective matrix, magnesium alloys have been reported to act antibacterial in vitro. To permit a basic assessment of antibacterial properties of implant materials in vivo an economic but robust animal model was established...
June 2016: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/26853541/papain-immobilized-polyurethane-as-an-ureteral-stent-material
#16
Cynthya Maria Manohar, Mukesh Doble
Long term use of polyurethane-based ureteral stent is hampered by the development of infection due to the formation of bacterial biofilm and salt deposition. Here papain, is covalently immobilized to polyurethane using glutarldehyde and is investigated as a possible anti-infective ureteral stent material. Fourier transform infrared spectrum confirmed its immobilization. Immobilized enzyme retained 85% of the activity of the free enzyme and about 12% loss of enzyme was observed from the polymer surface in one month...
May 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/26816637/surface-modification-of-biodegradable-magnesium-and-its-alloys-for-biomedical-applications
#17
REVIEW
Peng Tian, Xuanyong Liu
Magnesium and its alloys are being paid much attention recently as temporary implants, such as orthopedic implants and cardiovascular stents. However, the rapid degradation of them in physiological environment is a major obstacle preventing their wide applications to date, which will result in rapid mechanical integrity loss or even collapse of magnesium-based implants before injured tissues heal. Moreover, rapid degradation of the magnesium-based implants will also cause some adverse effects to their surrounding environment, such as local gas cavity around the implant, local alkalization and magnesium ion enrichment, which will reduce the integration between implant and tissue...
June 2015: Regenerative Biomaterials
https://www.readbyqxmd.com/read/26816631/absorbable-magnesium-based-stent-physiological-factors-to-consider-for-in-vitro-degradation-assessments
#18
REVIEW
Juan Wang, Christopher E Smith, Jagannathan Sankar, Yeoheung Yun, Nan Huang
Absorbable metals have been widely tested in various in vitro settings using cells to evaluate their possible suitability as an implant material. However, there exists a gap between in vivo and in vitro test results for absorbable materials. A lot of traditional in vitro assessments for permanent materials are no longer applicable to absorbable metallic implants. A key step is to identify and test the relevant microenvironment and parameters in test systems, which should be adapted according to the specific application...
March 2015: Regenerative Biomaterials
https://www.readbyqxmd.com/read/26652048/influence-of-surrounding-cations-on-the-surface-degradation-of-magnesium-alloy-implants-under-a-compressive-pressure
#19
Chengyun Ning, Lei Zhou, Ye Zhu, Ying Li, Peng Yu, Shuangying Wang, Tianrui He, Weiping Li, Guoxin Tan, Yingjun Wang, Chuanbin Mao
The effect of cations in the surrounding solutions on the surface degradation of magnesium alloys, a well-recognized biodegradable biomaterial, has been neglected compared with the effect of anions in the past. To better simulate the compressive environment where magnesium alloys are implanted into the body as a cardiovascular stent, a device is designed and employed in the test so that a pressure, equivalent to the vascular pressure, can be directly applied to the magnesium alloy implants when the alloys are immersed in a medium containing one of the cations (K(+), Na(+), Ca(2+), and Mg(2+)) found in blood plasma...
December 22, 2015: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/26560250/magnesium-stent-scaffolds-dreams-become-reality
#20
COMMENT
Antoine Lafont, Yi Yang
No abstract text is available yet for this article.
January 2, 2016: Lancet
keyword
keyword
46602
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"