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Molecular medical imaging

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https://www.readbyqxmd.com/read/28103204/transthoracic-ultrasonography-for-the-immunocompromised-patient-a-pilot-project-that-introduces-transthoracic-ultrasonography-for-the-follow-up-of-hematological-patients-in-romania
#1
Ioana Frinc, Petru Ilies, Florin Zaharie, Delia Dima, Alina Tanase, Ljubomir Petrov, Alexandru Irimie, Cristian Berce, Cosmin Lisencu, Ioana Berindan-Neagoe, Ciprian Tomuleasa, Anca Bojan
In the last decade, there is significant progress in clinical hematology with the discovery of targeted molecules and thus the achievement of both hematologic and molecular responses. Nevertheless, chemotherapy remains the treatment of choice for many types of hematological malignancies. Aggressive chemotherapy leads to immunosuppression, accompanied by a high rate of infections and an increased rate of treatment-related mortality. Invasive fungal infections, as well as more common bacterial and viral infections are frequent in immunocompromised patients as they are difficult to diagnose and treat...
January 18, 2017: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28102031/dual-nano-sized-contrast-agents-in-pet-mri-a-systematic-review
#2
REVIEW
Afsaneh Lahooti, Saeed Sarkar, Sophie Laurent, Saeed Shanehsazzadeh
Nowadays molecular imaging plays a vital role in achieving a successful targeted and personalized treatment. Hence, the approach of combining two or more medical imaging modalities was developed. The objective of this review is to systematically compare recent dual contrast agents in Positron Emission Tomography (PET)/Magnetic Resonance Imaging (MRI) and in some cases Single photon emission computed tomography (SPECT)/MRI in terms of some their characteristics, such as tumor uptake, and reticuloendothelial system uptake (especially liver) and their relaxivity rates for early detection of primary cancer tumor...
November 2016: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/28049492/current-status-and-perspectives-of-interventional-clinical-trials-for-glioblastoma-analysis-of-clinicaltrials-gov
#3
REVIEW
Nikola Cihoric, Alexandros Tsikkinis, Giuseppe Minniti, Frank J Lagerwaard, Ulrich Herrlinger, Etienne Mathier, Ivan Soldatovic, Branislav Jeremic, Pirus Ghadjar, Olgun Elicin, Kristina Lössl, Daniel M Aebersold, Claus Belka, Evelyn Herrmann, Maximilian Niyazi
The records of 208.777 (100%) clinical trials registered at ClinicalTrials.gov were downloaded on the 19th of February 2016. Phase II and III trials including patients with glioblastoma were selected for further classification and analysis. Based on the disease settings, trials were classified into three groups: newly diagnosed glioblastoma, recurrent disease and trials with no differentiation according to disease setting. Furthermore, we categorized trials according to the experimental interventions, the primary sponsor, the source of financial support and trial design elements...
January 3, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28048792/mo-de-206-01-cellular-metabolism-of-fdg
#4
G Pratx
: In this symposium jointly sponsored by the World Molecular Imaging Society (WMIS) and the AAPM, luminary speakers on imaging metabolism will discuss three impactful topics. The first presentation on Cellular Metabolism of FDG will be given by Guillem Pratx (Stanford). This presentation will detail new work on looking at how the most common molecular imaging agent, fluoro-deoxy-glucose is metabolized at a cellular level. This will be followed by a talk on an improved approach to whole-body PET imaging by Simon Cherry (UC Davis)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048692/mo-fg-207b-01-thorax-lung
#5
H Aerts
State-of-the-Art in Radiomics in Radiology and Radiation Oncology Radiomics is the science of converting medical images into mineable data, data that are descriptive of "phenotypes," which may provide diagnostic, prognostic, or therapeutic information. Genomics is the science of sequencing and analyzing the function and structure of genomes; the complete set of DNA in a single cell of an organism. In turn, imaging genomics (or radiogenomics) is concerned with the correlation between image-based features, as determined by radiomics, and gene expression, as determined by genomics...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048672/tu-c-horizons-01-the-expanding-horizons-travel-grant-program-eposters-and-discussion
#6
J Siewerdsen, R Jeraj
The Expanding Horizons travel grant program provides opportunity for students and trainees to broaden the scope of scientific meetings they attend and gain insight from research outside traditional domains of medical physics. Through participation in such conferences, early-career researchers are introduced to new topics with relevance to medical physics research as a means to expand the scientific horizons of our discipline. This year, 21 Expanding Horizons travel grants were awarded, granting travel to 17 conferences, including: Radiomics, the World Molecular Imaging Society (WMIS), the 3D Printing Conference and Expo, the GPU Technology Conference, the SIAM Imaging Science Conference, the Human Brain Mapping Conference, the OSA Conference on Clinical and Translational Biophotonics, the Society for Neuroscience, the AACR Conference on Tumor Microenvironment, and the Conference on Knowledge Discovery and Data Mining...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048430/we-fg-207b-03-multi-energy-ct-reconstruction-with-spatial-spectral-nonlocal-means-regularization
#7
B Li, C Shen, L Ouyang, M Yang, L Zhou, S Jiang, X Jia
PURPOSE: Multi-energy computed tomography (MECT) is an emerging application in medical imaging due to its ability of material differentiation and potential for molecular imaging. In MECT, image correlations at different spatial and channels exist. It is desirable to incorporate these correlations in reconstruction to improve image quality. For this purpose, this study proposes a MECT reconstruction technique that employes spatial spectral non-local means (ssNLM) regularization. METHODS: We consider a kVp-switching scanning method in which source energy is rapidly switched during data acquisition...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048367/th-a-207b-00-shear-wave-imaging-and-a-qiba-us-biomarker-update
#8
Paul Carson
: Imaging of tissue elastic properties is a relatively new and powerful approach to one of the oldest and most important diagnostic tools. Imaging of shear wave speed with ultrasound is has been added to most high-end ultrasound systems. Understanding this exciting imaging mode aiding its most effective use in medicine can be a rewarding effort for medical physicists and other medical imaging and treatment professionals. Assuring consistent, quantitative measurements across the many ultrasound systems in a typical imaging department will constitute a major step toward realizing the great potential of this technique and other quantitative imaging...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048135/mo-de-206-02-cellular-metabolism-of-fdg
#9
S Cherry
: In this symposium jointly sponsored by the World Molecular Imaging Society (WMIS) and the AAPM, luminary speakers on imaging metabolism will discuss three impactful topics. The first presentation on Cellular Metabolism of FDG will be given by Guillem Pratx (Stanford). This presentation will detail new work on looking at how the most common molecular imaging agent, fluoro-deoxy-glucose is metabolized at a cellular level. This will be followed by a talk on an improved approach to whole-body PET imaging by Simon Cherry (UC Davis)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048031/mo-fg-207b-02-breast
#10
H Li
State-of-the-Art in Radiomics in Radiology and Radiation Oncology Radiomics is the science of converting medical images into mineable data, data that are descriptive of "phenotypes," which may provide diagnostic, prognostic, or therapeutic information. Genomics is the science of sequencing and analyzing the function and structure of genomes; the complete set of DNA in a single cell of an organism. In turn, imaging genomics (or radiogenomics) is concerned with the correlation between image-based features, as determined by radiomics, and gene expression, as determined by genomics...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047721/th-a-207b-01-basics-and-current-implementations-of-ultrasound-imaging-of-shear-wave-speed-and-elasticity
#11
S Chen
: Imaging of tissue elastic properties is a relatively new and powerful approach to one of the oldest and most important diagnostic tools. Imaging of shear wave speed with ultrasound is has been added to most high-end ultrasound systems. Understanding this exciting imaging mode aiding its most effective use in medicine can be a rewarding effort for medical physicists and other medical imaging and treatment professionals. Assuring consistent, quantitative measurements across the many ultrasound systems in a typical imaging department will constitute a major step toward realizing the great potential of this technique and other quantitative imaging...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047484/mo-de-206-03-quantifying-metabolism-with-hyperpolarized-mr
#12
J Bankson
: In this symposium jointly sponsored by the World Molecular Imaging Society (WMIS) and the AAPM, luminary speakers on imaging metabolism will discuss three impactful topics. The first presentation on Cellular Metabolism of FDG will be given by Guillem Pratx (Stanford). This presentation will detail new work on looking at how the most common molecular imaging agent, fluoro-deoxy-glucose is metabolized at a cellular level. This will be followed by a talk on an improved approach to whole-body PET imaging by Simon Cherry (UC Davis)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047352/mo-fg-207b-03-brain
#13
P Tiwari
State-of-the-Art in Radiomics in Radiology and Radiation Oncology Radiomics is the science of converting medical images into mineable data, data that are descriptive of "phenotypes," which may provide diagnostic, prognostic, or therapeutic information. Genomics is the science of sequencing and analyzing the function and structure of genomes; the complete set of DNA in a single cell of an organism. In turn, imaging genomics (or radiogenomics) is concerned with the correlation between image-based features, as determined by radiomics, and gene expression, as determined by genomics...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047072/th-a-207b-02-qiba-ultrasound-elasticity-imaging-system-biomarker-qualification-and-user-testing-of-systems
#14
B Garra
: Imaging of tissue elastic properties is a relatively new and powerful approach to one of the oldest and most important diagnostic tools. Imaging of shear wave speed with ultrasound is has been added to most high-end ultrasound systems. Understanding this exciting imaging mode aiding its most effective use in medicine can be a rewarding effort for medical physicists and other medical imaging and treatment professionals. Assuring consistent, quantitative measurements across the many ultrasound systems in a typical imaging department will constitute a major step toward realizing the great potential of this technique and other quantitative imaging...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046736/mo-de-206-00-joint-aapm-wmis-symposium-metabolic-imaging-of-cancer
#15
John Hazle, Zaver Bhujwalla
: In this symposium jointly sponsored by the World Molecular Imaging Society (WMIS) and the AAPM, luminary speakers on imaging metabolism will discuss three impactful topics. The first presentation on Cellular Metabolism of FDG will be given by Guillem Pratx (Stanford). This presentation will detail new work on looking at how the most common molecular imaging agent, fluoro-deoxy-glucose is metabolized at a cellular level. This will be followed by a talk on an improved approach to whole-body PET imaging by Simon Cherry (UC Davis)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046682/mo-fg-207b-04-respond-to-therapy
#16
W Lu
State-of-the-Art in Radiomics in Radiology and Radiation Oncology Radiomics is the science of converting medical images into mineable data, data that are descriptive of "phenotypes," which may provide diagnostic, prognostic, or therapeutic information. Genomics is the science of sequencing and analyzing the function and structure of genomes; the complete set of DNA in a single cell of an organism. In turn, imaging genomics (or radiogenomics) is concerned with the correlation between image-based features, as determined by radiomics, and gene expression, as determined by genomics...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046637/mo-fg-207b-00-state-of-the-art-in-radiomics-in-radiology-and-radiation-oncology
#17
Maryellen Giger, Joseph Deasy
State-of-the-Art in Radiomics in Radiology and Radiation Oncology Radiomics is the science of converting medical images into mineable data, data that are descriptive of "phenotypes," which may provide diagnostic, prognostic, or therapeutic information. Genomics is the science of sequencing and analyzing the function and structure of genomes; the complete set of DNA in a single cell of an organism. In turn, imaging genomics (or radiogenomics) is concerned with the correlation between image-based features, as determined by radiomics, and gene expression, as determined by genomics...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043119/bioconjugated-nanoparticles-for-biosensing-in-vivo-imaging-and-medical-diagnostics
#18
Brad A Kairdolf, Ximei Qian, Shuming Nie
Bioconjugated nanoparticles are of considerable current interest because materials on the nanometer scale have unique optical, electronic, and magnetic properties with broad applications in biosensing, molecular imaging, and medical diagnostics. In particular, recent advances have led to the development of nanomaterials for a variety of applications, including iron oxide nanocrystals for magnetic resonance imaging (MRI), fluorescent quantum dots (QDs) for multiplexed molecular diagnosis and in vivo imaging, and gold nanoparticles for surface-enhanced Raman scattering...
December 19, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/28040141/prenatal-diagnosis-of-smith-magenis-syndrome-in-two-fetuses-with-increased-nuchal-translucency-mild-lateral-ventriculomegaly-and-congenital-heart-defects
#19
Ting-Ying Lei, Ru Li, Fang Fu, Jun-Hui Wan, Yong-Ling Zhang, Xiang-Yi Jing, Can Liao
OBJECTIVE: Smith-Magenis syndrome (SMS) is a multiple congenital anomalies/mental retardation disorder characterized by an interstitial deletion involving chromosome 17p11.2 containing the retinoic acid-induced 1 (RAI1) gene or due to mutation of RAI1. Few cases have been reported in the medical literature regarding prenatal diagnosis of SMS. We report on the prenatal diagnosis of SMS in two fetuses with increased nuchal translucency (NT), mild lateral ventriculomegaly, and congenital heart defects by whole-genome and high-resolution chromosome microarray analysis (CMA)...
December 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28033500/autonomous-assembly-of-ordered-metastable-dna-nanoarchitecture-and-in-situ-visualizing-of-intracellular-micrornas
#20
Jianguo Xu, Zai-Sheng Wu, Zhenmeng Wang, Jingqing Le, Tingting Zheng, Lee Jia
Facile assembly of intelligent DNA nanoobjects with the ability to exert in situ visualization of intracellular microRNAs (miRNAs) has long been concerned in the fields of DNA nanotechnology and basic medical study. Here, we present a driving primer (DP)-triggered polymerization-mediated metastable assembly (PMA) strategy to prepare a well-ordered metastable DNA nanoarchitecture composed of only two hairpin probes (HAPs), which has never been explored by assembly methods. Its structural features and functions are characterized by atomic force microscope (AFM) and gel electrophoresis...
December 22, 2016: Biomaterials
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