keyword
https://read.qxmd.com/read/38492129/lack-of-effects-of-eight-week-left-dorsolateral-prefrontal-theta-burst-stimulation-on-white-matter-macro-microstructure-and-connection-in-autism
#21
JOURNAL ARTICLE
Chun-Hung Yeh, Po-Chun Lin, Rung-Yu Tseng, Yi-Ping Chao, Chen-Te Wu, Tai-Li Chou, Rou-Shayn Chen, Susan Shur-Fen Gau, Hsing-Chang Ni, Hsiang-Yuan Lin
Whether brain stimulation could modulate brain structure in autism remains unknown. This study explored the impact of continuous theta burst stimulation (cTBS) over the left dorsolateral prefrontal cortex (DLPFC) on white matter macro/microstructure in intellectually able children and emerging adults with autism. Sixty autistic participants were randomized (30 active) and received active or sham cTBS for eight weeks twice per week, 16 total sessions using a double-blind (participant-, rater-, analyst-blinded) design...
March 16, 2024: Brain Imaging and Behavior
https://read.qxmd.com/read/38481459/autism-spectrum-disorder-comorbidity-and-demographics-in-a-clinical-sample
#22
JOURNAL ARTICLE
Fethiye Kilicaslan, Ali Evren Tufan
Objective: To determine the demographic and clinical characteristics of children followed up with the diagnosis of autism spectrum disorder (ASD) at a tertiary center in Southeeast Turkey. Methods: Children followed up with the diagnosis of ASD at a university hospital child psychiatry clinic between June 2016 and June 2021 were evaluated retrospectively for comorbidities, intellectual functioning and age at diagnosis. Results: In the preschool group, females displayed significantly more frequent cognitive developmental delay...
2024: International Journal of Developmental Disabilities
https://read.qxmd.com/read/38448025/-analysis-of-a-child-featuring-global-developmental-delay-and-autism-due-to-variant-of-tbr1-gene-and-a-literature-review
#23
REVIEW
Jinfeng Liu, Jia Zhang, Yajun Shen, Yang Li, Huan Luo, Jing Gan
OBJECTIVE: To explore the clinical characteristics and genetic basis for a child with global developmental delay and autism. METHODS: A child who had presented at West China Second University Hospital of Sichuan University on April 13, 2021 was selected as the study subject. Clinical manifestations, laboratory examination and result of genetic testing were analyzed. RESULTS: The main symptoms of the child had included cognitive, language and motor delay, autism and epilepsy...
March 10, 2024: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://read.qxmd.com/read/38435327/exploring-environmental-barriers-and-facilitators-to-inclusion-on-a-university-campus-for-autistic-students
#24
JOURNAL ARTICLE
Maxine O'Connor, Sandra C Jones, Chloe Gordon, Annette Joosten
BACKGROUND: Attending university allows individuals to build independence, develop social networks, and attain valuable qualifications, contributing to enhanced outcomes in adulthood. However, autistic people have poorer participation rates and outcomes in university than those with all other disabilities or without disabilities. Most research conducted with autistic young adults in the university environment focuses on their social and communicative challenges and supports rather than on how the physical environment impacts an autistic student's university experience...
March 1, 2024: Autism in adulthood: challenges and management
https://read.qxmd.com/read/38432883/roles-of-complement-system-in-psychiatric-disorders
#25
JOURNAL ARTICLE
Yajie Huo, Jie Chen, Aomei Zhang, Cuilan Zhou, Wenyu Cao
The complement system is an important part of the innate immune system, including more than 50 secretory proteins and membrane-bound proteins, and it contributes to the clearance of apoptotic cells and invading pathogens to limit inflammatory immune responses and maintaining brain homeostasis. Complement activity is strictly regulated to protect cells from random attacks or to prevent the deposition of complement proteins in physiological cases. However, overactivation or abnormal regulation of the complement cascade in the brain can lead to neuronal damage and brain dysfunction...
October 28, 2023: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://read.qxmd.com/read/38423713/screening-for-autism-a-review-of-the-current-state-ongoing-challenges-and-novel-approaches-on-the-horizon
#26
REVIEW
Kate E Wallis, Whitney Guthrie
Screening for autism is recommended in pediatric primary care. However, the median age of autism spectrum disorder (ASD) diagnosis is substantially higher than the age at which autism can reliably be identified, suggesting room for improvements in autism recognition at young ages, especially for children from minoritized racial and ethnic groups, low-income families, and families who prefer a language other than English. Novel approaches are being developed to utilize new technologies in aiding in autism recognition...
April 2024: Pediatric Clinics of North America
https://read.qxmd.com/read/38423538/influence-of-parental-education-on-the-intelligence-quotient-profiles-and-socially-adaptive-behavior-of-school-age-children-with-autism-spectrum-disorder-in-eastern-china
#27
JOURNAL ARTICLE
Wenhao Li, Chao Song, Lifei Hu, Lingling Wu, Zhiwei Zhu
Intelligence quotient (IQ) and adaptive behavior are the influencing factors of autism spectrum disorder (ASD) in children entering mainstream schools. This study explored the association between parental education level, IQ, and adaptive behavior in ASD groups. A total of 257 school-age ASD children were enrolled in our study from January 2017 to June 2021. Their parents completed a standard demographic form, including age at autism diagnosis, gender, school placement, and parents' educational background. The Chinese version of the Wechsler Intelligence Scale for Children, Fourth Edition (WISC-IV) was completed by a certified assessor for each enrolled child...
February 8, 2024: Journal of Zhejiang University. Science. B
https://read.qxmd.com/read/38421790/autistic-traits-are-associated-with-differences-in-the-perception-of-genuineness-and-approachability-in-emotional-facial-expressions-independently-of-alexithymia
#28
JOURNAL ARTICLE
Ellen Bothe, Linda Jeffery, Amy Dawel, Bronte Donatti-Liddelow, Romina Palermo
People with autism and higher levels of autistic traits often have difficulty interpreting facial emotion. Research has commonly investigated the association between autistic traits and expression labeling ability. Here, we investigated the association between two relatively understudied abilities, namely, judging whether expressions reflect genuine emotion, and using expressions to make social approach judgements, in a nonclinical sample of undergraduates at an Australian university ( N = 149; data collected during 2018)...
February 29, 2024: Emotion
https://read.qxmd.com/read/38410675/a-bibliometric-analysis-of-autism-spectrum-disorder-signaling-pathways-research-in-the-past-decade
#29
JOURNAL ARTICLE
Kaifeng Lyu, Jiangshan Li, Min Chen, Wu Li, Wei Zhang, Meichao Hu, Yuxing Zhang, Xiang Feng
BACKGROUND: This study employs bibliometric methods to comprehensively understand the fundamental structure of research about Autism Spectrum Disorder (ASD) Signaling Pathways by examining key indicators such as nations, institutions, journals, authors, and keywords. METHODOLOGY: We utilized the WoScc database to retrieve literature relevant to ASD Signaling Pathways published between 2013 and 2023. Through visual analysis and tools like CiteSpace and VosViewer, we explored nations, institutions, journals, authors, and keywords, thereby constructing relevant networks...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38362218/locked-down-locked-in-experiences-of-families-of-young-children-with-autism-spectrum-disorders-in-delhi-india
#30
JOURNAL ARTICLE
Abhipreet Kaur, Gitanjali Lall, Minal Abhilashi, Lavangi Naithani, Mamta Verma, Reetabrata Roy, Monica Juneja, Sheffali Gulati, Carol Taylor, Kathy Leadbitter, Vikram Patel, Jonathan Green, Gauri Divan
INTRODUCTION: The onset of the COVID-19 pandemic and subsequent lockdowns in March 2020 disrupted the lives of families across India. The lockdown related restrictions brought forth a multitude of challenges including loss of employment, social isolation, school closures and financial burdens. Specifically, it also resulted in the restriction of health-care services for children with neurodevelopmental disabilities. METHODS: This qualitative study was conducted as a part of a larger trial in India to understand the experiences of families of young children with autism during the pandemic...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38358708/similar-social-attention-physiological-arousal-and-familiarity-effect-in-autistic-and-neurotypical-children-a-real-life-recreational-eye-tracking-paradigm
#31
JOURNAL ARTICLE
Elise Clin, Eleanor Miller, Mikhail Kissine
Social attention is reported to be crucial for the development of social skills, and, according to the social cognitive developmental theory, is fostered by social interactions. Autism is of central importance to the study of social attention, as autism is characterized by atypical social interactions and low social attention, both linked according to the social motivation theory to diminished social interest. Much evidence for positing low social interest in autism comes from eye-tracking studies, which, however, lack ecological validity...
February 15, 2024: Journal of Experimental Psychology. General
https://read.qxmd.com/read/38335372/correlation-analysis-of-maternal-condition-during-pregnancy-with-head-circumference-and-autism-spectrum-disorder-a-propensity-score-matched-study
#32
JOURNAL ARTICLE
Lei Liu, Shichun Zhao
To determine whether health status during pregnancy is associated with autism spectrum disorder (ASD) and abnormal head circumference (HC) in the offspring. This study included 41 Han children with ASD who visited the Children's Health Clinic of the Second Hospital of Shandong University between March 2018 and February 2019, and 264 Han children with typical development (TD) who visited the clinic during the same period. Physical measurements were performed on the children. The questionnaire obtained information on maternal risk factors that may be related to the increased risk of ASD and folic acid (FA) supplementation...
February 9, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38323322/periodic-and-aperiodic-changes-to-cortical-eeg-in-response-to-pharmacological-manipulation
#33
JOURNAL ARTICLE
Sofia V Salvatore, Peter M Lambert, Ann Benz, Nicholas R Rensing, Michael Wong, Charles F Zorumski, Steven J Mennerick
Cortical electroencephalograms (EEG) may help understanding of neuropsychiatric illness and new treatment mechanisms. The aperiodic component (1/ f ) of EEG power spectra is often treated as noise, but recent studies suggest that changes to the aperiodic exponent of power spectra may reflect changes in excitation/inhibition balance, a concept linked to antidepressant effects, epilepsy, autism, and other clinical conditions. One confound of previous studies is behavioral state, because factors associated with behavioral state other than excitation/inhibition ratio may alter EEG parameters...
February 7, 2024: Journal of Neurophysiology
https://read.qxmd.com/read/38312009/parental-mental-illness-and-the-likelihood-of-child-out-of-home-care-a-cohort-study
#34
JOURNAL ARTICLE
Alicia Nevriana, Kyriaki Kosidou, Holly Hope, Susanne Wicks, Christina Dalman, Matthias Pierce, Kathryn M Abel
OBJECTIVES: To detail the relationship between parental mental illness and the likelihood of out-of-home care (OHC) among their children, and to identify factors which modify this relationship. METHODS: Using Swedish national registers, children born in 2000 to 2011 (n = 1 249 463) were linked to their parents. Time-dependent parental mental illness (nonaffective and affective psychosis, substance misuse, depression, anxiety and stress, eating disorders, personality disorders, attention deficit hyperactivity disorder, autism, and intellectual disability), was identified through International Classification of Diseases codes...
March 1, 2024: Pediatrics
https://read.qxmd.com/read/38311602/what-are-the-autism-research-priorities-of-autistic-adults-in-scotland
#35
JOURNAL ARTICLE
Eilidh Cage, Catherine J Crompton, Sarah Dantas, Khiah Strachan, Rachel Birch, Mark Robinson, Stasa Morgan-Appel, Charlie MacKenzie-Nash, Aaron Gallagher, Monique Botha
Although research has the potential to improve autistic people's lives, lots of funding goes towards research looking at topics which autistic people say has little impact in their everyday lives. Autistic people's lives can be different depending on where they live, and Scotland is a unique country in many ways. We wanted to find out which topics autistic people in Scotland want to see research on. Our team of autistic and non-autistic researchers (including university-based and community researchers) created a survey where 225 autistic adults rated and ranked the importance of possible research topics and shared their thoughts on what topics mattered to them...
February 4, 2024: Autism: the International Journal of Research and Practice
https://read.qxmd.com/read/38281738/descriptive-analysis-of-social-interaction-and-communication-skills-of-autistic-children-according-to-sibling-status-and-characteristics
#36
JOURNAL ARTICLE
Se Yeon Kim, Da-Yea Song, Guiyoung Bong, Jae Hyun Han, Hee Jeong Yoo
OBJECTIVE: Sibling relationships in early childhood can have a positive impact on children's social interaction and communication skills. Similarly, autistic children can benefit from interactions with their siblings, who can serve as readily available partners for social interaction. However, there is a lack of research on the effects of siblings based on specific characteristics of the sibling. Therefore, the aim of this study is to compare social interactions and communication skills of autistic children based on sibling status and characteristics...
January 2024: Psychiatry Investigation
https://read.qxmd.com/read/38279835/two-validation-studies-of-a-performance-validity-test-for-autistic-adults
#37
JOURNAL ARTICLE
Anke M Scheeren, Linda Olde Dubbelink, Anne Geeke Lever, Hilde M Geurts
In two studies we examined the potential of a simple emotion recognition task, the Morel Emotional Numbing Test (MENT), as a performance validity test (PVT) for autism-related cognitive difficulties in adulthood. The aim of a PVT is to indicate non-credible performance, which can aid the interpretation of psychological assessments. There are currently no validated PVTs for autism-related difficulties in adulthood. In Study 1, non-autistic university students (aged 18-46 years) were instructed to simulate that they were autistic during a psychological assessment (simulation condition; n  = 26)...
January 27, 2024: Applied Neuropsychology. Adult
https://read.qxmd.com/read/38248358/ube3a-the-role-in-autism-spectrum-disorders-asds-and-a-potential-candidate-for-biomarker-studies-and-designing-therapeutic-strategies
#38
REVIEW
Bidisha Roy, Enyonam Amemasor, Suhail Hussain, Kimberly Castro
Published reports from the CDC's Autism and Development Disabilities Monitoring Networks have shown that an average of 1 in every 44 (2.3%) 8-year-old children were estimated to have ASD in 2018. Many of the ASDs exhibiting varying degrees of autism-like phenotypes have chromosomal anomalies in the Chr15q11-q13 region. Numerous potential candidate genes linked with ASD reside in this chromosomal segment. However, several clinical, in vivo, and in vitro studies selected one gene more frequently than others randomly and unbiasedly...
December 27, 2023: Diseases (Basel)
https://read.qxmd.com/read/38241984/eating-disorder-in-children-impact-on-quality-of-life-with-a-spotlight-on-autism-spectrum-disorder
#39
REVIEW
Natalia A Smolko, Rushan I Valiev, Ilyas M Kabdesh, Rezeda A Fayzullina, Yana O Mukhamedshina
Eating behavior, which includes eating habits and preferences, frequency of eating, and other features related to diet, is a major characteristic not only of a person's nutritional status, but also of health in general. In recent years, the prevalence of eating disorders in children has tended to increase; they also require cross-system approaches in diagnosis by a variety of specialists and correction requires appropriate selection of optimal methods. Maladaptive eating attitudes formed at an early age can contribute to the formation of eating disorders, which can lead to or worsen various neuropsychiatric diseases, digestive diseases, and other related conditions...
December 22, 2023: Nutrition Research
https://read.qxmd.com/read/38228768/autistic-traits-and-speech-perception-in-social-and-non-social-noises
#40
JOURNAL ARTICLE
Yurika Tsuji, Shu Imaizumi
Individuals with the autism spectrum disorder (ASD) experience difficulties in perceiving speech in background noises with temporal dips; they also lack social orienting. We tested two hypotheses: (1) the higher the autistic traits, the lower the performance in the speech-in-noise test, and (2) individuals with high autistic traits experience greater difficulty in perceiving speech, especially in the non-vocal noise, because of their attentional bias toward non-vocal sounds. Thirty-eight female Japanese university students participated in an experiment measuring their ability to perceive speech in the presence of noise...
January 16, 2024: Scientific Reports
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