Tulip Marawi, Peter Zhukovsky, Heather Brooks, Christopher R Bowie, Meryl A Butters, Corinne E Fischer, Alastair J Flint, Nathan Herrmann, Krista L Lanctôt, Linda Mah, Bruce G Pollock, Tarek K Rajji, Aristotle N Voineskos, Benoit H Mulsant
OBJECTIVES: To identify data-driven cognitive profiles in older adults with remitted major depressive disorder (rMDD) with or without mild cognitive impairment (MCI) and examine how the profiles differ regarding demographic, clinical, and neuroimaging measures. DESIGN: Secondary cross-sectional analysis using latent profile analysis. SETTING: Multisite clinical trial in Toronto, Canada. PARTICIPANTS: One hundred seventy-eight participants who met DSM-5 criteria for rMDD without MCI (rMDD-MCI; n = 60) or with MCI (rMDD + MCI; n = 118)...
February 2, 2024: American Journal of Geriatric Psychiatry