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https://www.readbyqxmd.com/read/27909337/optimization-of-the-optical-transparency-of-rodent-tissues-by-modified-pact-based-passive-clearing
#1
Jiwon Woo, Mirae Lee, Jeong Min Seo, Hyo Suk Park, Yong Eun Cho
Recently, a bio-electrochemical technique known as CLARITY was reported for three-dimensional phenotype mapping within transparent tissues, allowing clearer whole-body and organ visualization with CB-perfusion (CUBIC) and leading to the development of whole-body clearing and transparency of intact tissues with the PACT (passive clarity technique) and PARS (perfusion-assisted agent release in situ) methodologies. We evaluated the structure-function relationships in circuits of the whole central nervous system (CNS) and various internal organs using improved methods with optimized passive clarity...
December 2, 2016: Experimental & Molecular Medicine
https://www.readbyqxmd.com/read/27890526/femoropopliteal-in-stent-restenosis-repair-midterm-outcomes-after-paclitaxel-eluting-balloon-use-plaisir-trial
#2
N Bague, P Julia, A Sauguet, J M Pernès, P Chatelard, J F Garbé, S Penillon, J M Cardon, P Commeau, O Planché, B Guyomarch, Y Gouëffic
OBJECTIVE: The aim was to assess 18 month outcomes of the paclitaxel eluting balloon (PEB) in patients with femoropopliteal (FP) in-stent restenosis (ISR). METHODS: In a national prospective and multicentre cohort study, symptomatic patients with femoropopliteal in-stent restenosis were included from January 2012 to June 2013. Patients were treated by paclitaxel eluting balloon angioplasty (In Pact Admiral, Medtronic, Santa Rosa, CA, USA). Clinical and duplex scan follow-up evaluations were performed at 1, 3, 6, 9, 12, and 18 months...
November 24, 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27884360/cost-effectiveness-of-endovascular-femoropopliteal-intervention-using-drug-coated-balloons%C3%A2-versus-standard-percutaneous-transluminal-angioplasty-results-from-the-in-pact%C3%A2-sfa-ii-trial
#3
Adam C Salisbury, Haiyan Li, Katherine R Vilain, Michael R Jaff, Peter A Schneider, John R Laird, David J Cohen
OBJECTIVES: The aim of this study was to evaluate the cost-effectiveness of drug-coated balloon (DCB) angioplasty versus standard percutaneous transluminal angioplasty (PTA). BACKGROUND: Recent trials have reported lower rates of target lesion revascularization with DCB angioplasty versus standard PTA. However, the cost-effectiveness of DCB angioplasty is unknown. METHODS: A prospective economic study was performed alongside the IN.PACT SFA II (IN...
November 28, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27875650/military-genitourinary-trauma-policies-implications-and-ethics
#4
Wendy K Dean, Arthur L Caplan, Brendan Parent
The men and women who serve in the armed forces, in the words of Major General Joseph Caravalho, "sign a blank check, co-signed by their families, payable to the Army, Navy, Air Force, or Marines, up to and including their lives." It is human nature to consider such a pact in polarized terms; the pact concludes in either a celebratory homecoming or funereal mourning. But in reality, surviving catastrophic injury may incur the greatest debt. The small but real possibility of losing the ability to bear biological children due to genitourinary combat injury has been a topic of discussion in hushed tones, behind closed doors...
November 2016: Hastings Center Report
https://www.readbyqxmd.com/read/27869974/-evaluating-productivity-targets-achievement-in-dental-specialty-centers-from-maranh%C3%A3-o-state-brazil-2011
#5
Erika Bárbara Abreu Fonseca Thomaz, Grazianne Medeiros Carvalho de Sousa, Rejane Christine de Sousa Queiroz, Liberata Campos Coimbra
OBJECTIVE: to evaluate productivity targets achievement (PTA) in Dental Specialty Centers (DSCs) from Maranhão State, Brazil. METHODS: this was an ecologic study using secondary data; an indicator for PTA was created for each subgroup of procedures. RESULTS: 25 DSCs were evaluated; the PTA was higher for basic procedures (n=19), followed by endodontics (n=11), oral surgery (n=9) and periodontics (n=8); the best results were obtained at DSCs type II; higher PTA was associated with financial anticipation (basic procedures) and higher Human Development Index, life expectancy and social exclusion rate (endodontics); lower PTA was associated with larger population (endodontics/oral surgery), adherence to the Pact for Health (periodontics/endodontics), larger number of specialties (periodontics) and bigger DSC (oral surgery)...
October 2016: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/27861888/double-hanging-with-single-ligature-an-unusual-method-in-suicide-pact
#6
Chittaranjan Behera, Ravi Rautji, Rajesh Kumar, Shashank Pooniya, Piyush Sharma, Sudhir Kumar Gupta
A married casual labor couple was found hanging in their makeshift bedroom with each end of a single chunni (a cloth worn around the neck by Indian women) spread across an iron bar below the roof. They left their two children, daughter, and son of 4 and 3 yrs age, respectively, with their grandmother living separately nearby, and went to attend cremation of one of their relatives. They returned late in the evening and found hanging in their bedroom next morning by neighbors.
November 11, 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27848416/parent-led-early-intervention-can-reduce-symptom-severity
#7
(no author information available yet)
In the original Preschool Autism Communication Trial (PACT), published in 2010, 152 children aged 2-4 with autism were randomised to receive usual treatment or a 12-month early intervention.
November 9, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27846895/development-and-validation-of-a-prehospital-prediction-model-for-acute-traumatic-coagulopathy
#8
Ithan D Peltan, Ali Rowhani-Rahbar, Lisa K Vande Vusse, Ellen Caldwell, Thomas D Rea, Ronald V Maier, Timothy R Watkins
BACKGROUND: Acute traumatic coagulopathy (ATC) is a syndrome of early, endogenous clotting dysfunction that afflicts up to 30% of severely injured patients, signaling an increased likelihood of all-cause and hemorrhage-associated mortality. To aid identification of patients within the likely therapeutic window for ATC and facilitate study of its mechanisms and targeted treatment, we developed and validated a prehospital ATC prediction model. METHODS: Construction of a parsimonious multivariable logistic regression model predicting ATC - defined as an admission international normalized ratio >1...
November 16, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27828674/development-health-and-international-policy-the-research-and-innovation-dimension
#9
Paulo Marchiori Buss, Claudia Chamas, Miriam Faid, Carlos Morel
This text main objective is to discuss development and health from the perspective of the influence of global health governance, using as the tracer the dimension of research, development, and innovation policies in health, which relate to both important inputs for the health system, like drugs and medicines, vaccines, diagnostic reagents, and equipment, and innovative concepts and practices for the improvement of health systems and public health. The authors examine the two main macro-processes that influence development and health: the post-2015 Development Agenda and the process under way in the World Health Organization concerning research and development, intellectual property, and access to health inputs...
November 3, 2016: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/27819750/female-urinary-incontinence-and-sexuality
#10
Renato Lains Mota
Urinary incontinence is a common problem among women and it is estimated that between 15 and 55% of them complain of lower urinary symptoms. The most preva¬lent form of urinary incontinence is associated with stress, followed by mixed urinary incontinence and urge urinary incontinence. It is a symptom with several effects on quality of life of women mainly in their social, familiar and sexual domains. Female reproductive and urinary systems share anatomical structures, which promotes that urinary problems interfere with sexual function in females...
November 2, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27798224/amphetamine-enhances-gains-in-auditory-discrimination-training-in-adult-schizophrenia-patients
#11
Neal R Swerdlow, Melissa Tarasenko, Savita G Bhakta, Jo Talledo, Alexis I Alvarez, Erica L Hughes, Brinda Rana, Sophia Vinogradov, Gregory A Light
Targeted cognitive training (TCT) of auditory processing enhances higher-order cognition in schizophrenia patients. TCT performance gains can be detected after 1 training session. As a prelude to a potential clinical trial, we assessed a pharmacological augmentation of cognitive therapy (PACT) strategy by testing if the psychostimulant, amphetamine, augments TCT gains in auditory processing speed (APS) in schizophrenia patients and healthy subjects (HS). HS and schizophrenia patients were tested in a screening session (test 1), followed by a double-blind crossover design (tests 2-3), comparing placebo vs amphetamine (10 mg; 7 d between tests)...
October 25, 2016: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/27798022/parenting-acceptance-and-commitment-therapy-a-randomised-controlled-trial-of-an-innovative-online-course-for-families-of-children-with-cerebral-palsy
#12
Koa Whittingham, Jeanie Sheffield, Roslyn N Boyd
INTRODUCTION: Cerebral palsy (CP) impacts on the entire family in a manner that is long-term, complex and multifactorial. In addition, the quality of the parent-child relationship impacts on many and varied child outcomes, making the provision of easily accessible and evidence-based support to parents of children with CP a priority. This paper reports the protocol of a randomised controlled trial of an innovative and translatable online intervention, parenting acceptance and commitment therapy (PACT), for families of children with CP...
October 19, 2016: BMJ Open
https://www.readbyqxmd.com/read/27797567/psychometric-properties-of-the-pact-scale-and-relations-with-symptoms-of-ptsd
#13
Caitlin M Pinciotti, Antonia V Seligowski, Holly K Orcutt
Objective: Healing from trauma has been conceptualized as either facing the trauma head-on or moving beyond the trauma and focusing on the future. Emerging research suggests that the greatest healing may result from the ability to adaptively use both (i.e., coping flexibility). The current study sought to examine the psychometric properties of a self-report scale of coping flexibility: the Perceived Ability to Cope With Trauma (PACT) Scale. Method: Participants included 322 undergraduate students enrolled in an introductory psychology course at a large Midwestern university...
October 31, 2016: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/27796836/erratum-to-can-we-create-a-canadian-perioperative-anesthesia-clinical-trials-group-we-review-the-first-five-years-and-glimpse-into-the-future
#14
Richard Hall, Scott Beattie, Hilary P Grocott, C David Mazer, Alexis F Turgeon, André Denault, Homer Yang, Manoj M Lalu, Ronald B George, Sonia Sampson, Heather McDonald
No abstract text is available yet for this article.
October 27, 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/27793431/parent-mediated-social-communication-therapy-for-young-children-with-autism-pact-long-term-follow-up-of-a-randomised-controlled-trial
#15
Andrew Pickles, Ann Le Couteur, Kathy Leadbitter, Erica Salomone, Rachel Cole-Fletcher, Hannah Tobin, Isobel Gammer, Jessica Lowry, George Vamvakas, Sarah Byford, Catherine Aldred, Vicky Slonims, Helen McConachie, Patricia Howlin, Jeremy R Parr, Tony Charman, Jonathan Green
BACKGROUND: It is not known whether early intervention can improve long-term autism symptom outcomes. We aimed to follow-up the Preschool Autism Communication Trial (PACT), to investigate whether the PACT intervention had a long-term effect on autism symptoms and continued effects on parent and child social interaction. METHODS: PACT was a randomised controlled trial of a parent-mediated social communication intervention for children aged 2-4 years with core autism...
November 19, 2016: Lancet
https://www.readbyqxmd.com/read/27789820/data-check-how-a-figure-key-to-new-hfc-pact-was-born
#16
Warren Cornwall
No abstract text is available yet for this article.
October 28, 2016: Science
https://www.readbyqxmd.com/read/27783780/impacts-of-a-documentary-on-the-daily-lives-of-mothers-and-children-with-disabilities-an-analysis-of-cine-debates
#17
Fátima Gonçalves Cavalcante, Luciana Ferreira Lau, Gabriella Ferrarese Barbosa, Daniela Lima Gomes Berlim, Natasha Coelho Menezes, Daniela de Carvalho Braga, Annibal Coelho de Amorim, Yuri Cavalcante Amorim
The article analyzes the impact of a documentary on the daily lives of mothers and children with disabilities, exhibited at conferences, festivals, universities and schools in Brazil, Colombia and Japan. Produced by film and health professionals, social scientists and a women's network, the feature film "A special day" was awarded at Assim Vivemos VI International Disability Film Festival (2013-2014). The objective is to analyze the impact of the film and its diffusion among professionals and students from health and education areas...
October 2016: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/27783777/social-protection-and-people-with-disabilities-in-brazil
#18
Nilson do Rosário Costa, Miguel Abud Marcelino, Cristina Maria Rabelais Duarte, Deborah Uhr
The article analyzes the social protection policy for people with disabilities in Brazil. It describes the patterns of demand and eligibility for Continued Benefit of Social Assistance (Benefício de Prestação Continuada - BPC) in the 1996-2014 period. The article argues that BPC is a direct result of the social pact achieved by the Brazilian Federal Constitution of 1988. BPC is a social assistance benefit consisting in an unconditional and monthly transference of the equivalent of a minimum wage, to poor people with deficiency and elders with more than 65 years...
October 2016: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/27779163/effects-of-roughly-focused-extracorporeal-shock-waves-therapy-on-the-expressions-of-bone-morphogenetic-protein-2-and-osteoprotegerin-in-osteoporotic-fracture-in-rats
#19
Hai-Ming Huang, Xiao-Lin Li, Shu-Qiang Tu, Xiao-Feng Chen, Chang-Chun Lu, Liang-Hua Jiang
BACKGROUND: Roughly focused extracorporeal shock waves therapy (ESWT) is characterized by a wide focal area, a large therapy zone, easy positioning, and less pain during treatment. The purpose of this study was to investigate the effects of roughly focused ESWT on the expression of osteoprotegerin (OPG) and bone morphogenetic protein-2 (BMP-2) in osteoporotic fractures in rats. METHODS: Seventy-two female Sprague-Dawley (SD) rats, 3 months old, were divided into sham-operated group (n = 6) and an ovariectomized (OVX) group (n = 66)...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27771367/in-pact%C3%A2-admiral%C3%A2-drug-coated-balloon-durable-consistent-and-safe-treatment-for-femoropopliteal-peripheral-artery-disease
#20
REVIEW
Susan Peterson, Melissa Hasenbank, Claudio Silvestro, Shashank Raina
Endovascular management of peripheral artery disease was until recently limited to percutaneous balloon angioplasty, atherectomy, stent grafts, and bare-metal stents. These therapies have been valuable, but plagued by high restenosis and revascularization rates. Important progress has been made with the introduction of combination devices, including drug-eluting stents and drug-coated balloons (DCB), designed to combat restenosis by locally delivering anti-proliferative drugs. In particular, promising clinical performance has been seen with the Medtronic IN...
October 19, 2016: Advanced Drug Delivery Reviews
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