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https://www.readbyqxmd.com/read/28533466/cultural-evolution-of-military-camouflage
#1
Laszlo Talas, Roland J Baddeley, Innes C Cuthill
While one has evolved and the other been consciously created, animal and military camouflage are expected to show many similar design principles. Using a unique database of calibrated photographs of camouflage uniform patterns, processed using texture and colour analysis methods from computer vision, we show that the parallels with biology are deeper than design for effective concealment. Using two case studies we show that, like many animal colour patterns, military camouflage can serve multiple functions...
July 5, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28532194/cost-effectiveness-of-ceftolozane-tazobactam-plus-metronidazole-compared-with-piperacillin-tazobactam-as-empiric-therapy-for-the-treatment-of-complicated-intra-abdominal-infections-based-on-the-in-vitro-surveillance-of-bacterial-isolates-in-the-uk
#2
Vimalanand Prabhu, Jason Foo, Harblas Ahir, Eric Sarpong, Sanjay Merchant
AIMS: An increase in the prevalence of antimicrobial resistance among gram-negative pathogens has been noted recently.[1] A challenge in empiric treatment of complicated intra-abdominal infection (cIAI) is identifying initial appropriate antibiotic therapy, which is associated with reduced length of stay and mortality compared with inappropriate therapy. The objective of this study was to assess the cost-effectiveness of ceftolozane/tazobactam+metronidazole compared with piperacillin/tazobactam (commonly used in this indication) in the treatment of patients with cIAI in United Kingdom (UK) hospitals...
May 22, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28525318/evaluation-of-genotype-guided-acenocoumarol-dosing-algorithms-in-russian-patients
#3
Dmitriy Alexeyevich Sychev, Aleksandr Vladimirovich Rozhkov, Anna Viktorovna Ananichuk, Ruslan Evgenyevich Kazakov
BACKGROUND: Acenocoumarol dose is normally determined via step-by-step adjustment process based on International Normalized Ratio (INR) measurements. During this time, the risk of adverse reactions is especially high. Several genotype-based acenocoumarol dosing algorithms have been created to predict ideal doses at the start of anticoagulant therapy. MATERIALS AND METHODS: Nine dosing algorithms were selected through a literature search. These were evaluated using a cohort of 63 patients with atrial fibrillation receiving acenocoumarol therapy...
May 17, 2017: Drug Metabolism and Personalized Therapy
https://www.readbyqxmd.com/read/28514996/post-autopsy-computed-tomography-pros-and-cons-in-a-firearm-death
#4
Sindi Visentin, Guido Pelletti, Caterina Dengo, Maria De Matteis, Massimo Montisci
Many studies have focused on the importance of post-mortem computed tomography (PMCT) prior to or in substitution of standard forensic autopsies in case of firearm death. However, due to the fact that PMCT is not routinely performed in all countries, in cases of death abroad it can happen that a CT scan is performed only after a first autopsy. A case of post-mortem re-examination, including the external examination and a post-autopsy computed tomography (PACT), of a gunshot victim of homicide in a foreign country is presented, and the pros and cons of imaging in post-autopsy setting are discussed...
May 1, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28511852/introducing-a-checking-technician-allows-pharmacists-to-spend-more-time-on-patient-focused-activities
#5
Patti Napier, Pauline Norris, Rhiannon Braund
BACKGROUND: Internationally there is an increasing focus on the clinical and cognitive services that pharmacists can provide. Lack of time has been identified as a barrier to pharmacists increasing their clinical activities. Within the pharmacy workplace there are many tasks that can only be performed by a pharmacist. The final accuracy check of a dispensed prescription is currently the sole responsibility of pharmacists in New Zealand. This takes up a significant amount of time during a pharmacist's work day...
May 11, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28493985/photodynamic-antimicrobial-chemotherapy-with-the-novel-amino-acid-porphyrin-conjugate-4i-in-vitro-and-in-vivo-studies
#6
Yao Yuan, Zi-Quan Liu, Heng Jin, Shi Sun, Tian-Jun Liu, Xue Wang, Hao-Jun Fan, Shi-Ke Hou, Hui Ding
Photodynamic antimicrobial chemotherapy (PACT), as a novel and effective therapeutic modality to eradicate drug resistant bacteria without provoking multidrug resistance, has attracted increasing attention. This study examined the antimicrobial efficacy of the novel cationic amino acid-porphyrin conjugate 4I with four lysine groups against two different clinical isolated strains (drug sensitive and multidrug resistant) of the Acinetobacter baumannii species and its toxicity on murine dermal fibroblasts in vitro, as well as the therapeutic effect of PACT on acute, potentially lethal multidrug resistant strain excisional wound infections in vivo...
2017: PloS One
https://www.readbyqxmd.com/read/28483953/ceftolozane-tazobactam-activity-against-pseudomonas-aeruginosa-clinical-isolates-from-us-hospitals-report-from-an-antimicrobial-surveillance-program-pacts-2012-2015
#7
Dee Shortridge, Mariana Castanheira, Michael A Pfaller, Robert K Flamm
The activity of ceftolozane-tazobactam was compared to the activity of 7 antimicrobials against 3,851 Pseudomonas aeruginosa isolates collected from 32 US hospitals in the Program to Assess Ceftolozane-Tazobactam Susceptibility from 2012-2015. Ceftolozane-tazobactam and comparator susceptibilities were determined using the CLSI broth microdilution method at a central monitoring laboratory. For ceftolozane-tazobactam, 97.0% of the isolates were susceptible. Susceptibilities of the other antibacterials tested were: amikacin, 96...
May 8, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28482217/ruthenium-ii-complexes-of-saccharin-with-dipyridoquinoxaline-and-dipyridophenazine-structures-biological-interactions-and-photoinduced-dna-damage-activity
#8
Priyaranjan Kumar, Srikanth Dasari, Ashis K Patra
Ruthenium complexes trans-[Ru(sac)2(dpq)2] (1) and trans-[Ru(sac)2(dppz)2] (2) where sac is artificial sweetener saccharin (o-sulfobenzimide; 1,2-benzothiazole-3(2H)-one1,1-dioxide (Hsac)), dpq = dipyrido[3,2-d:2',3'-f]quinoxaline and dppz = dipyrido[3,2-a:2',3'-c]phenazine have been synthesized and thoroughly characterized using various analytical and spectral techniques. Saccharin known to act as carbonic anhydrase IX (CA IX) inhibitor which is a biomarker for highly aggressive and proliferative tumor in hypoxic stress, so inhibition of CA IX is a potential strategy for anticancer chemotherapy...
May 3, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28481843/vha-patient-centered-medical-home-associated-with-lower-rate-of-hospitalizations-and-specialty-care-among-veterans-with-posttraumatic-stress-disorder
#9
Ian Randall, David C Mohr, Charles Maynard
OBJECTIVE: The Veterans Health Administration (VHA) implemented a patient-centered medical home (PCMH) model, termed Patient Aligned Care Teams (PACT), in 2010. We assessed the association between PACT and the use of health services among U.S. veterans with posttraumatic stress disorder (PTSD). METHODS: VHA clinical and administrative data were obtained for the pre-PACT period of April 1, 2009 to March 31, 2010 and post-PACT period of June 1, 2011 to May 31, 2012...
May 2017: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
https://www.readbyqxmd.com/read/28476427/clinical-phenotypes-of-perinatal-depression-and-time-of-symptom-onset-analysis-of-data-from-an-international-consortium
#10
Karen T Putnam, Marsha Wilcox, Emma Robertson-Blackmore, Katherine Sharkey, Veerle Bergink, Trine Munk-Olsen, Kristina M Deligiannidis, Jennifer Payne, Margaret Altemus, Jeffrey Newport, Gisele Apter, Emmanuel Devouche, Alexander Viktorin, Patrik Magnusson, Brenda Penninx, Anne Buist, Justin Bilszta, Michael O'Hara, Scott Stuart, Rebecca Brock, Sabine Roza, Henning Tiemeier, Constance Guille, C Neill Epperson, Deborah Kim, Peter Schmidt, Pedro Martinez, Arianna Di Florio, Katherine L Wisner, Zachary Stowe, Ian Jones, Patrick F Sullivan, David Rubinow, Kevin Wildenhaus, Samantha Meltzer-Brody
BACKGROUND: The perinatal period is a time of high risk for onset of depressive disorders and is associated with substantial morbidity and mortality, including maternal suicide. Perinatal depression comprises a heterogeneous group of clinical subtypes, and further refinement is needed to improve treatment outcomes. We sought to empirically identify and describe clinically relevant phenotypic subtypes of perinatal depression, and further characterise subtypes by time of symptom onset within pregnancy and three post-partum periods...
May 3, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28471291/thomas-mann-s-depiction-of-neurosyphilis-and-other-diseases
#11
François Boller, Nicoletta Caputi
Thomas Mann (1875-1955), a Nobel Prize recipient rightly considered one of the great novelists of the twentieth century, was one of the most medically perceptive writers of recent times. His novels take place against the background of the different plagues (tuberculosis, cholera) that characterized the eighteenth and nineteenth centuries. One of Mann's later novels, Doctor Faustus, is set against a background of syphilis. In the 500-page book, which is subtitled The Life of the German Composer Adrian Leverkühn as told by a Friend, we see the theologian turned composer make a pact with the devil...
May 4, 2017: Journal of the History of the Neurosciences
https://www.readbyqxmd.com/read/28465993/right-ventricular-outflow-tract-systolic-excursion-and-fractional-shortening-can-these-echocardiographic-parameters-be-used-for-the-assessment-of-right-ventricular-function
#12
Lamyaa Elsayed Allam, Ahmed Mohammed Onsy, Hylan Ahmed Ghalib
BACKGROUND: Echocardiographic right ventricular (RV) function assessment is difficult and still a gray area despite rapid advancement of imaging modalities. The aim of this study is to assess the role of echocardiographic RV outflow tract (RVOT) function in the form of RVOT fractional shortening (RVOT FS) and RVOT systolic excursion (RVOT SE) for the assessment of RV function. METHODS: We studied ninety individuals divided equally into two groups. The control group included 45 normal healthy individuals and age-matched patient group included 45 patients with RV dysfunction which was defined by tricuspid annular plane systolic excursion (TAPSE) <16 mm and RV fractional area change (RV FAC) ≤35%...
April 2017: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/28464935/provision-of-peer-specialist-services-in-va-patient-aligned-care-teams-protocol-for-testing-a-cluster-randomized-implementation-trial
#13
Matthew Chinman, Karin Daniels, Jeff Smith, Sharon McCarthy, Deborah Medoff, Amanda Peeples, Richard Goldberg
BACKGROUND: Over 1100 Veterans work in the Veterans Health Administration (VHA) as peer specialists (PSs). PSs are Veterans with formal training who provide support to other Veterans with similar diagnoses, primarily in mental health settings. A White House Executive Action mandated the pilot reassignment of VHA PSs from mental health to 25 primary care Patient Aligned Care Teams (PACT) in order to broaden the provision of wellness services that can address many chronic illnesses. An evaluation of this initiative was undertaken to assess the impact of outside assistance on the deployment of PS in PACT, as implementation support is often needed to prevent challenges commonly experienced when first deploying PSs in VHA settings...
May 2, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28444053/a-systematic-review-of-the-process-of-regionalization-of-brazil-s-unified-health-system-sus
#14
Guilherme Arantes Mello, Ana Paula Chancharulo de Morais Pereira, Liza Yurie Teruya Uchimura, Fabíola Lana Iozzi, Marcelo Marcos Piva Demarzo, Ana Luiza d'Ávila Viana
This review focuses only on specific studies into the SUS regionalization process, which were based on empirical results and published since 2006, when the SUS was already under the aegis of the Pact for Health framework. It was found that the regionalization process is now underway in all spheres of government, subject to a set of challenges common to the different realities of the country. These include, primarily, that committee-structured entities are valued as spaces for innovation, yet also strive to overcome the bureaucratic and clientelist political culture...
April 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28406644/influence-of-the-steric-bulk-and-solvent-on-the-photoreactivity-of-ruthenium-polypyridyl-complexes-coordinated-to-l-proline
#15
Jordi-Amat Cuello-Garibo, Elena Pérez-Gallent, Lennard van der Boon, Maxime A Siegler, Sylvestre Bonnet
Ruthenium polypyridyl complexes are good candidates for photoactivated chemotherapy (PACT) provided that they are stable in the dark but efficiently photosubstitute one of their ligands. Here the use of the natural amino acid l-proline as a protecting ligand for ruthenium-based PACT compounds is investigated in the series of complexes Λ-[Ru(bpy)2(l-prol)]PF6 ([1a]PF6; bpy = 2,2'-bipyridine and l-prol = l-proline), Λ-[Ru(bpy)(dmbpy)(l-prol)]PF6 ([2a]PF6 and [2b]PF6; dmbpy = 6,6'-dimethyl-2,2'-bipyridine), and Λ-[Ru(dmbpy)2(l-prol)]PF6 ([3a]PF6)...
May 1, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28385413/what-does-the-in-pact-sfa-long-study-tell-us
#16
EDITORIAL
Osamu Iida, Mitsuyoshi Takahara, Toshiaki Mano
No abstract text is available yet for this article.
April 10, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28333700/intimate-partner-violence-a-rare-case-of-reciprocal-homicide
#17
Aurélie Cauchois, François Paraire, Geoffroy Lorin de la Grandmaison
We present the case of a reciprocal homicide by stabbing that occurred within an unmarried couple without known history of spousal violence. Each partner killed the other one at the same time and at the same place using kitchen knives. They were both found dead at home lying on the floor after the neighbors heard an argument and screams coming from the couple's apartment, so they called the police and the fire department. The door was locked from the inside, and the fire department was forced to break the door...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28314524/development-of-the-japanese-version-of-the-psychosocial-assessment-of-candidates-for-transplantation-in-allogeneic-hematopoietic-stem-cell-transplantation
#18
Saki Harashima, Ryo Yoneda, Takeshi Horie, Mami Kayano, Yosei Fujioka, Fumihiko Nakamura, Mineo Kurokawa, Kazuhiro Yoshiuchi
BACKGROUND: The Psychosocial Assessment of Candidates for Transplantation (PACT) is a validated instrument for evaluating psychosocial risk factors in transplant candidates. OBJECTIVES: This study examined reliability and validity of the Japanese version of the PACT (J-PACT). METHODS: PACT is a clinician-rated scale consisting of an initial rating, 8 subscales, and a final rating. J-PACT was developed through a translation and back-translation procedure...
January 19, 2017: Psychosomatics
https://www.readbyqxmd.com/read/28296722/design-methodology-and-baseline-data-of-the-personalized-addition-lenses-clinical-trial-pact
#19
RANDOMIZED CONTROLLED TRIAL
Xinping Yu, Binjun Zhang, Jinhua Bao, Junxiao Zhang, Ge Wu, Jinling Xu, Jingwei Zheng, Björn Drobe, Hao Chen
BACKGROUND: The aim of this study was to describe the design, methods, and baseline characteristics of children enrolled in the Personalized Addition lenses Clinical Trial (PACT). PACT aims to test the myopia control efficacy of progressive addition lenses (PALs) with personalized addition values compared with standard (+2.00 D) addition PALs and single vision lenses (SVLs). METHODS: PACT is a randomized, controlled, double-masked clinical trial. Two hundred eleven myopic Chinese children (7-12 years) were enrolled and randomized into 1 of the 3 following groups: personalized addition PALs; +2...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28284586/do-bedsider-family-planning-mobile-text-message-and-e-mail-reminders-increase-kept-appointments-and-contraceptive-coverage
#20
Heike Thiel de Bocanegra, Mary Bradsberry, Carrie Lewis, Fran Maguire
OBJECTIVE: To determine whether Bedsider text message and e-mail reminders increase family planning contraceptive continuation and appointment rates. MATERIAL AND METHODS: We trained staff at three high-volume Family Planning, Access, Care, and Treatment (Family PACT) clinics to enroll women through a special portal to receive text message or e-mail reminders for contraceptive refills and clinic appointments. Women were matched by contraceptive method, time frame of index visit, age group, and language preference to Family PACT clients at comparison sites that did not use the Bedsider program...
March 9, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
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