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https://www.readbyqxmd.com/read/28060137/infants-with-congenital-zika-syndrome-and-ocular-findings-from-s%C3%A3-o-paulo-brazil-spread-of-infection
#1
João Rafael de Oliveira Dias, Camila V Ventura, Paula Delegrego Borba, Bruno de Paula Freitas, Ligia Camera Pierroti, Ana Patricia do Nascimento, Nilva Simeren Bueno de Moraes, Maurício Maia, Rubens Belfort
BACKGROUND/PURPOSE: To describe the ocular findings of two infants with congenital Zika syndrome born in São Paulo state, Brazil, outside the primary outbreak region. METHODS: Two female infants with congenital Zika syndrome were submitted to a complete screening for infectious diseases, as well as ocular examination, fundus photography, and optical coherence tomography of the retina. One of the infants was submitted to ocular ultrasound. RESULTS: Both children showed positive serology for Zika virus, and other infectious diseases were ruled out...
January 2, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28058165/evaluation-of-follow-up-and-treatment-results-in-coats-disease
#2
Zafer Cebeci, Şerife Bayraktar, Yusuf Cem Yılmaz, Samuray Tuncer, Nur Kır
OBJECTIVES: The aim of this study was to evaluate the clinical features, follow-up and treatment results of patients diagnosed with Coats' disease. MATERIALS AND METHODS: Medical records of 27 patients diagnosed with Coats' disease in our clinic were reviewed retrospectively. All patients underwent complete ophthalmological examination and fundus photography was taken. Disease stage and treatment methods used were recorded. RESULTS: Twenty-seven eyes of 27 patients were included in the study...
October 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28058151/characteristics-of-fundus-autofluorescence-in-active-polypoidal-choroidal-vasculopathy
#3
Zafer Öztaş, Jale Menteş, Serhad Nalçacı, Mine Barış
OBJECTIVES: To define characteristic fundus autofluorescence (FAF) findings in eyes with active polypoidal choroidal vasculopathy (PCV). MATERIALS AND METHODS: Thirty-five eyes of 29 patients with active PCV who were diagnosed at Ege University Faculty of Medicine, Department of Ophthalmology, Retina Division between January 2012 and November 2014 were included in the study. All the patients underwent a complete ophthalmological examination including fundus photography, spectral-domain optical coherence tomography, fluorescein angiography, FAF photography, and indocyanine green angiography (ICGA)...
August 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27966268/ophthalmological-findings-in-children-with-encephalitis
#4
Kerstin Hellgren, Åsa Fowler, Agneta Rydberg, Ronny Wickström
PURPOSE: To evaluate ophthalmological abnormalities in children with acute encephalitis. METHODS: Thirty-six children included in a hospital-based prospectively and consecutively collected cohort of children with acute encephalitis were investigated for ophthalmological abnormalities. The investigation included clinical ophthalmological examination, fundus photography, neuro-ophthalmological examinations as well as visual and stereo acuity. Results on laboratory examinations, clinical findings, neuroimaging and electroencephalography registrations were recorded for all children...
December 14, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27938959/six-year-prevalence-and-incidence-of-diabetic-retinopathy-and-cost-effectiveness-of-tele-ophthalmology-in-manitoba
#5
Raageen Kanjee, Ravi I Dookeran, Mathen K Mathen, Frank A Stockl, Richard Leicht
OBJECTIVE: The purpose of this study was to evaluate the diabetic retinopathy (DR) tele-ophthalmology screening program in Manitoba to determine prevalence and incidence of DR, as well as to estimate the program's cost-effectiveness. DESIGN: Retrospective chart review. PARTICIPANTS: A total of 4676 patients with type 2 diabetes examined 9334 times from 2007 to 2013. METHODS: Focused ophthalmic histories were recorded and examinations were performed by trained nurses, including visual acuities, intraocular pressure, and mydriatic 7 standard field stereoscopic fundus photography...
December 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/27907042/role-of-platelet-parameters-on-neovascular-glaucoma-a-retrospective-case-control-study-in-china
#6
Shengjie Li, Wenjun Cao, Xinghuai Sun
PURPOSE: Retinal vein occlusion (RVO) and diabetic retinopathy (DR) are two major sight-threatening diseases which may lead to neovascular glaucoma (NVG). The aim of this study was to explore the association between platelet parameters and NVG. METHODS: A total of 185 subjects were enrolled for the study from January, 2012 to December, 2015 at the Eye-ENT Hospital of Fudan University. Patients include those with NVG secondary to RVO (RVO group, n = 38), patients with NVG secondary to DR (DR group, n = 47), diabetics mellitus without retinopathy (DM group, n = 52), and healthy individuals (control group, n = 48)...
2016: PloS One
https://www.readbyqxmd.com/read/27802518/diagnostic-performance-of-peripapillary-retinal-nerve-fiber-layer-thickness-for-detection-of-glaucoma-in-an-elderly-population-the-alienor-study
#7
Cedric Schweitzer, Jean-Francois Korobelnik, Melanie Le Goff, Olivier Rahimian, Florence Malet, Marie-Benedicte Rougier, Marie-Noelle Delyfer, Jean-Francois Dartigues, Cecile Delcourt
Purpose: To assess diagnostic accuracy of spectral-domain optical coherence tomography (SD-OCT) to discriminate glaucoma and control subjects in an elderly population. Methods: The antioxidants, essential lipids, nutrition and ocular maladies study (ALIENOR: "Antioxydants, Lipides Essentiels, Nutrition et Maladies Oculaires") is a population-based study. From 2009 to 2010, a total of 624 subjects, aged 74 years or older underwent a complete eye examination, including optic disc color photography and SD-OCT examination of the macula and the optic nerve head...
November 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27778447/distribution-of-intraocular-pressure-central-corneal-thickness-and-vertical-cup-to-disc-ratio-in-a-healthy-iranian-population-the-yazd-eye-study
#8
Mohammad Pakravan, Mohammad Ali Javadi, Shahin Yazdani, Elham Ghahari, Zohreh Behroozi, Reza Soleimanizad, Sasan Moghimi, Naveed Nilforoushan, Reza Zarei, Yadollah Eslami, Mahmood Ghassami, Hossein Ziaei, Marzieh Katibeh, Hanif Tabesh, Mehdi Yaseri
PURPOSE: To determine the distribution of intraocular pressure (IOP), central corneal thickness (CCT) and vertical cup-to-disc ratio (VCDR) in the healthy Iranian population. METHODS: This population-based, epidemiologic study evaluated Iranian aged 40-80 years, residing in Yazd, Iran, in 2010-2011. Eligible subjects were selected by cluster random sampling. Each participant underwent an interview and ophthalmologic examination including slit lamp examination, Goldmann applanation tonometry, binocular optic disc evaluation, stereoscopic fundus photography, ultrasonic pachymetry and visual field testing...
October 25, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27685535/influence-of-computer-generated-mosaic-photographs-on-retinopathy-of-prematurity-diagnosis-and-management
#9
Samir N Patel, Michael A Klufas, Christina E Douglas, Karyn E Jonas, Susan Ostmo, Audina Berrocal, Antonio Capone, Maria A Martinez-Castellanos, Felix Chau, Kimberly Drenser, Philip Ferrone, Anton Orlin, Irena Tsui, Wei-Chi Wu, Mrinali P Gupta, Michael F Chiang, R V Paul Chan
Importance: Telemedicine is becoming an increasingly important component of clinical care for retinopathy of prematurity (ROP), but little information exists regarding the role of mosaic photography for ROP telemedicine diagnosis. Objective: To examine the potential effect of computer-generated mosaic photographs on the diagnosis and management of ROP. Design, Setting, and Participants: In this prospective cohort study performed from July 12, 2011, through September 21, 2015, images were acquired from ROP screening at 8 academic institutions, and ROP experts interpreted 40 sets (20 sets with individual fundus photographs with ≥3 fields and 20 computer-generated mosaic photographs) of wide-angle retinal images from infants with ROP...
September 29, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/27628287/-handheld-optical-coherence-tomography-in-paediatric-ophthalmology-experience-of-the-department-of-ophthalmology-in-giessen
#10
W Bowl, M Andrassi-Darida, K Holve, S Schweinfurth, R Knobloch, B Lorenz
Introduction: Optical coherence tomography is an important tool for the imaging and analysis of retinal structures. The usability of conventional table-top devices is limited in children. We report on our experiences with a handheld Spectral Domain Optical Coherence Tomography (HH-SD-OCT, Bioptigen™) in infants and young children in our daily practice. Methods: Between October 2014 and April 2016, we investigated 259 patients. Indications and diagnoses were assessed. Individual examples are shown to demonstrate the advantages and disadvantages of the novel technique...
October 2016: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/27584715/effect-of-a-matrix-therapy-agent-on-corneal-epithelial-healing-after-standard-collagen-cross-linking-in-patients-with-keratoconus-a-randomized-clinical-trial
#11
Ahmed M Bata, Katarzyna J Witkowska, Piotr A Wozniak, Klemens Fondi, Gerald Schmidinger, Niklas Pircher, Stephan Szegedi, Valentin Aranha Dos Santos, Anca Pantalon, René M Werkmeister, Gerhard Garhofer, Leopold Schmetterer, Doreen Schmidl
Importance: Corneal abrasions are frequent after standard (epithelium-off [epi-off]) corneal collagen cross-linking (CXL) in patients with progressive keratoconus. A new matrix therapy agent (ReGeneraTing Agent [RGTA]) has been developed to promote corneal wound healing. Objective: To assess the effect of the new type of matrix therapy agent on corneal wound healing after epi-off CXL in patients with keratoconus. Design, Setting, and Participants: This double-masked randomized clinical trial enrolled 40 patients with keratoconus undergoing epi-off CXL from July 18, 2014, to October 21, 2015, when the last follow-up was completed...
October 1, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/27537414/retinal-sequelae-in-adults-treated-with-cryotherapy-for-retinopathy-of-prematurity
#12
Maria Nilsson, Ann Hellström, Lena Jacobson
PURPOSE: Cryotherapy, introduced in the mid-1980s, was the first treatment of severe retinopathy of prematurity (ROP) and resulted in ablation of larger retinal areas than did its later substitute, laser treatment. We defined the characteristics of the retinal structure and assessed visual function, in adult ex-preterms treated with cryotherapy. METHODS: A total of 28 ex-preterms, included in a prospective study of infants born in Stockholm between September 1988 and March 1993, were treated with cryotherapy because of severe ROP...
July 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27529778/intravitreal-methotrexate-for-mantle-cell-lymphoma-infiltration-of-the-optic-nerves-a-case-report
#13
James R Singer, Archana K Nigalye, Mary T Champion, Matthew J Welch
PURPOSE: To report the successful treatment of a 78-year-old woman with bilateral mantle cell lymphoma involving the optic nerves. Chemotherapy initially was administered in the form of intravitreal methotrexate (MTX) monotherapy and was subsequently combined with systemic ibrutinib. METHODS: Retrospective case report. The diagnosis of CD5-negative mantle cell lymphoma was confirmed via immunohistopathological analysis of an axillary lymph node. Serial ophthalmologic examinations in conjunction with fluorescein angiography, fundus photography, and spectral domain optical coherence tomography were used to assess the treatment response...
August 12, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27521170/clinical-and-genetic-characteristics-of-japanese-patients-with-age-related-macular-degeneration-and-pseudodrusen
#14
Sufian Elfandi, Sotaro Ooto, Naoko Ueda-Arakawa, Ayako Takahashi, Munemitsu Yoshikawa, Hideo Nakanishi, Hiroshi Tamura, Akio Oishi, Kenji Yamashiro, Nagahisa Yoshimura
PURPOSE: To investigate differences in clinical characteristics and genotype distribution in Japanese patients with age-related macular degeneration (AMD) and pseudodrusen using multimodal imaging. DESIGN: Retrospective, observational case series. PARTICIPANTS: A total of 101 patients (101 eyes) with AMD and pseudodrusen. METHODS: Patients underwent complete ophthalmologic examination, including color fundus photography, infrared reflectance (IR) imaging, fundus autofluorescence, confocal blue reflectance, fluorescein and indocyanine green (ICG) angiography, and spectral-domain optical coherence tomography (SD OCT)...
October 2016: Ophthalmology
https://www.readbyqxmd.com/read/27486012/ocular-morphology-and-function-in-juvenile-neuronal-ceroid-lipofuscinosis-cln3-in-the-first-decade-of-life
#15
Markus N Preising, Michaela Abura, Melanie Jäger, Klaus-Heiko Wassill, Birgit Lorenz
PURPOSE: CLN3 is a rare lysosomal storage disorder. The majority of the patients suffer from neurological degeneration in the first decade of life leading to death in the second or third decade. One of the first symptoms is a rapid visual decline from retinal degeneration. The aim of this study was to correlate the retinal changes in CLN3 as seen with spectral domain optical coherence tomography (SD-OCT) with functional data in patients in the first years after the subjective onset of ocular symptoms...
August 2, 2016: Ophthalmic Genetics
https://www.readbyqxmd.com/read/27378278/the-effect-of-cilostazol-on-electrophysiologic-changes-in-non-proliferative-diabetic-retinopathy-patients
#16
Hoon Dong Kim, Si Hyoung Lee, Yoon Kyoung Kim, Jong Rok Oh, Young-Hoon Ohn
PURPOSE: To evaluate the effects of cilostazol, an antiplatelet and vasodilation agent, on the retinal function of patients with non-proliferative diabetic retinopathy (NPDR) using a full-field electroretinogram (ffERG). METHODS: A total of 20 eyes from 20 patients were enrolled as the cilostazol-treated group, and 16 eyes from 16 patients were enrolled as the control group to assess the functional effects of cilostazol. Ophthalmologic examinations including fundus fluorescein angiography (FFA), fundus color photography, optical coherence tomography (OCT), and ffERG responses were recorded at baseline and after 1 year of cilostazol treatment...
August 2016: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/27377657/plasma-e-selectin-levels-can-play-a-role-in-the-development-of-diabetic-retinopathy
#17
Márta Kasza, J Meleg, J Vardai, B Nagy, E Szalai, J Damjanovich, A Csutak, B Ujhelyi, V Nagy
PURPOSE: Diabetic retinopathy is one of the leading causes of blindness. There are several risk factors, such as the duration of diabetes or glycemic control of the patient; however, several biochemical factors also alter the process. Our aim was to investigate the role of soluble E-selectin in the formation of diabetic retinopathy. PATIENTS AND METHODS: Fifty-seven patients (37 female and 20 male, aged 61.71 ± 12.31 years) and 14 healthy control subjects (ten female and four male, aged 63...
January 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27373393/change-in-light-scattering-caused-by-glistenings-in-hydrophobic-acrylic-intraocular-lenses-from-10-to-15%C3%A2-years-after-surgery
#18
Eva Mönestam, Anders Behndig
PURPOSE: To analyze the long-term change in light scattering caused by glistenings in hydrophobic acrylic intraocular lenses (IOLs) and the clinical implications on high-contrast and low-contrast visual acuity. SETTING: Department of Clinical Sciences/Ophthalmology, Umeå University Hospital, Umeå, Sweden. DESIGN: Prospective longitudinal case series. METHODS: The study comprised patients who had an Acrysof MA60BM IOL implanted between 1997 and 1998...
June 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27340878/undiagnosed-primary-open-angle-glaucoma-in-korea-the-korean-national-health-and-nutrition-examination-survey-2008-2009
#19
Na Rae Kim, Hee Seung Chin, Gong Je Seong, Chan Yun Kim
PURPOSE: To evaluate the characteristics of patients with previously undiagnosed primary open-angle glaucoma (POAG) in Korea. METHODS: This study examined data from 391 subjects obtained from the 2008-2009 Korean National Health and Nutrition Examination Survey (KNHANES). The KNHANES is a population-based, cross-sectional epidemiological survey. Participants aged 19 years or older completed standardized interviews and dilated ocular examinations, including measurement of intraocular pressure, visual fields with frequency doubling perimetry, and fundus photography...
August 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27302683/fundus-photography-with-a-smartphone-in-indirect-ophthalmoscopy-in-dogs-and-cats
#20
Nobuyuki Kanemaki, Mizuho Inaniwa, Kunihiko Terakado, Shinpei Kawarai, Yoichiro Ichikawa
OBJECTIVE: To introduce a simple method for fundus photography of dogs and cats using a smartphone and indirect ophthalmoscopy lenses. METHODS: Fundus photographs of dogs and cats with transparent ocular media were obtained with 15D, 20D, 28D, and 40D indirect lenses and an iPhone-6, in a dark room and after pharmacologic pupil dilation. The photographs were recorded as still images using a video application and a video-to-still image application. Two types of neutral density (ND) filters were used as required for reduction of the torch illumination power of the iPhone...
June 15, 2016: Veterinary Ophthalmology
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