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Neonicotinoid

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https://www.readbyqxmd.com/read/29775568/neonicotinoids-decrease-sucrose-responsiveness-of-honey-bees-at-first-contact
#1
Fabien J Démares, Christian W W Pirk, Susan W Nicolson, Hannelie Human
For two decades, neonicotinoid insecticides have been extensively used worldwide. Targeting neuronal receptors, they have deleterious effects on the behaviour and physiology of many of many beneficial as well as harmful insects. Bees are exposed to these insecticides in pollen and nectar while providing pollination services to agricultural crops, and neonicotinoids have been shown to impair navigation by bees and to decrease their foraging activity. We have previously reported the effect of dietary thiamethoxam on sucrose responsiveness of young worker bees...
May 15, 2018: Journal of Insect Physiology
https://www.readbyqxmd.com/read/29772515/simultaneous-determination-of-nine-neonicotinoids-in-human-urine-using-isotope-dilution-ultra-performance-liquid-chromatography-tandem-mass-spectrometry
#2
Quan Zhang, Ximing Wang, Zhe Li, Hangbiao Jin, Zhengbiao Lu, Chang Yu, Yu-Fang Huang, Meirong Zhao
Neonicotinoids (neonics), a class of systemic insecticides, have been frequently detected in pollen, vegetables, and fruits. Recently, an increasing concern has been aroused for human exposure to neonics. However, biological monitoring for quantifying body burden of neonics has rarely been reported. In this study, we developed an isotope-dilution ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS) method to simultaneously quantify nine neonics, including acetamiprid (ACE), thiamethoxam (THIAM), imidacloprid (IMIP), clothianidin (CLO), flonicamid (FLO), thiacloprid (THIAC), dinotefuran (DIN), nitenpyram (NIT), and imidaclothiz (IMIT) in urine...
May 14, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29764654/drivers-of-colony-losses
#3
REVIEW
Nathalie Steinhauer, Kelly Kulhanek, Karina Antúnez, Hannelie Human, Panuwan Chantawannakul, Marie-Pierre Chauzat, Dennis vanEngelsdorp
Over the past decade, in some regions of the world, honey bee (Apis mellifera L.) colonies have experienced rates of colony loss that are difficult for beekeepers to sustain. The reasons for losses are complex and interacting, with major drivers including Varroaand related viruses, pesticides, nutrition and beekeeper practices. In these endeavors it has also become apparent that defining a dead colony, and singling out the effects of specific drivers of loss, is not so straightforward. Using the class of neonicotinoid pesticides as an example we explain why quantifying risk factor impact at the colony level is at times elusive and in some cases unpractical...
April 2018: Current Opinion in Insect Science
https://www.readbyqxmd.com/read/29758240/imidacloprid-intensifies-its-impact-on-honeybee-and-bumblebee-cellular-immune-response-when-challenged-with-lps-lippopolysacharide-of-escherichia-coli
#4
Louise Walderdorff, Philippe Laval-Gilly, Antoine Bonnefoy, Jaïro Falla-Angel
Insect hemocytes play an important role in insects' defense against environmental stressors as they are entirely dependent on their innate immune system for pathogen defense. In recent years a dramatic decline of pollinators has been reported in many countries. The drivers of this declines appear to be associated with pathogen infections like viruses, bacteria or fungi in combination with pesticide exposure. The aim of this study was thus to investigate the impact of imidacloprid, a neonicotinoid insecticide, on the cellular immune response of two pollinators (Apis mellifera and Bombus terrestris) during simultaneous immune activation with LPS (lipopolysaccharide) of Escherichia coli...
May 11, 2018: Journal of Insect Physiology
https://www.readbyqxmd.com/read/29757520/controlling-culex-pipiens-antagonists-are-more-efficient-than-a-neonicotinoid-insecticide
#5
Alvine Larissa Meyabeme Elono, Kaarina Foit, Sabine Duquesne, Matthias Liess
Species vulnerability to pesticides depends on physiological sensitivity, the potential to recover, and the ecological context. We assessed the vulnerability of the mosquito Culex pipiens to a repeated treatment with thiacloprid in outdoor microcosms with and without antagonists (competitive and predatory invertebrates). Microcosms were treated repeatedly (three times) with thiacloprid at a concentration of 0.1, 1, or 10 µg/liter. In microcosms without antagonists, the abundance of Cx. pipiens larvae decreased moderately after the second and the third exposures to 10 µg/liter thiacloprid...
June 2018: Journal of Vector Ecology: Journal of the Society for Vector Ecology
https://www.readbyqxmd.com/read/29757232/ultrasonically-modified-amended-cloud-point-extraction-for-simultaneous-pre-concentration-of-neonicotinoid-insecticide-residues
#6
Rawikan Kachangoon, Jitlada Vichapong, Rodjana Burakham, Yanawath Santaladchaiyakit, Supalax Srijaranai
An effective pre-concentration method, namely amended-cloud point extraction (CPE), has been developed for the extraction and pre-concentration of neonicotinoid insecticide residues. The studied analytes including clothianidin, imidacloprid, acetamiprid, thiamethoxam and thiacloprid were chosen as a model compound. The amended-CPE procedure included two cloud point processes. Triton™ X-114 was used to extract neonicotinoid residues into the surfactant-rich phase and then the analytes were transferred into an alkaline solution with the help of ultrasound energy...
May 12, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29754059/selectivity-assessment-of-two-biorational-insecticides-azadirachtin-and-pyriproxyfen-in-comparison-to-a-neonicotinoid-acetamiprid-on-pupae-and-adults-of-a-neotropical-strain-eretmocerus-mundus-mercet
#7
Natalia Francesena, Marcela Inés Schneider
Assessment of the susceptibility of natural enemies of pests to selective pesticides is relevant for a sustainable agriculture with low impact on the environment. The aim of this study was to assess the toxicity of two biorational insecticides, azadirachtin and pyriproxyfen in comparison to a neonicotinoid insecticide, acetamiprid, on pupae and adults of a Neotropical strain of Eretmocerus mundus. Adult emergence and survival were evaluated as lethal effects whereas the sublethal effects were assessed through the reproductive capacity, sex ratio, and longevity of the surviving first progeny...
May 2, 2018: Chemosphere
https://www.readbyqxmd.com/read/29753712/focc%C3%AE-6-a-truncated-nachr-subunit-positively-correlates-with-spinosad-resistance-in-the-western-flower-thrips-frankliniella-occidentalis-pergande
#8
Yanran Wan, Guangdi Yuan, Bingqing He, Baoyun Xu, Wen Xie, Shaoli Wang, Youjun Zhang, Qingjun Wu, Xuguo Zhou
Nicotinic acetylcholine receptors (nAChRs), a molecular target for spinosyns and neonicotinoids, mediate rapid cholinergic transmission in insect central nervous system by binding acetylcholine. Previous studies have shown that mutations in nAChRs contribute to the high level of resistance to these two classes of insecticides. In this study, we identified nine nAChR subunits from a transcriptome of the western flower thrips, Frankliniella occidentalis, including α1-7, β1, and β2. Exon 4 of α4 and exons 3 and 8 of α6 each have two splicing variants, respectively...
May 10, 2018: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29741606/influence-of-imidacloprid-and-horticultural-oil-on-spider-abundance-on-eastern-hemlock-in-the-southern-appalachians
#9
A Hakeem, J F Grant, P L Lambdin, F A Hale, J R Rhea, G J Wiggins, C Coots
Hemlock woolly adelgid, Adelges tsugae Annand (Hemiptera: Adelgidae), is an exotic pest of eastern hemlock, Tsuga canadensis (L.) Carrière (Pinales: Pinaceae), in the eastern United States. Two commonly used insecticides to manage adelgid are imidacloprid, a systemic neonicotinoid insecticide, and horticultural oil, a refined petroleum oil foliar spray. We have investigated the influence of imidacloprid and horticultural oil on spider abundance at different canopy strata in eastern hemlock. In total, 2,084 spiders representing 11 families were collected from the canopies of eastern hemlock...
May 8, 2018: Environmental Entomology
https://www.readbyqxmd.com/read/29738731/toxicology-bee-p450s-take-the-sting-out-of-cyanoamidine-neonicotinoids
#10
René Feyereisen
The neonicotinoid insecticides have raised concerns regarding the health of bee pollinators. New research has identified a P450 enzyme that protects honey bees and bumble bees from the toxicity of two neonicotinoids, thiacloprid and acetamiprid. This P450 enzyme provides a margin of safety to bees.
May 7, 2018: Current Biology: CB
https://www.readbyqxmd.com/read/29735281/simultaneous-determination-of-neonicotinoid-insecticides-and-insect-growth-regulators-residues-in-honey-using-lc-ms-ms-with-anion-exchanger-disposable-pipette-extraction
#11
Shiming Song, Cuifang Zhang, Zhaojie Chen, Fengmei He, Jie Wei, Huihua Tan, Xuesheng Li
In this study, we developed an anion exchanger-disposable pipette extraction (DPX) method to detect the residual concentrations of eight neonicotinoid insecticides (dinotefuran, acetamiprid, clothianidin, thiacloprid, imidachloprid, imidaclothiz, nitenpyram, and thiamethoxam) and eight insect growth regulators (IGRs; triflumuron, cyromazine, buprofezin, methoxyfenozide, tebufenozide, chromafenozide, fenoxycarb, and RH 5849) in Chinese honey samples collected from different floral sources and different geographical regions using liquid chromatography tandem mass spectrometry (LC-MS/MS)...
May 3, 2018: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29720321/three-quarters-of-world-s-honey-contain-neonicotinoids
#12
Aline Mutabazi, Blaise Mulhauser, Matthieu Mulot, Alexandre Aebi, Edward A D Mitchell, Gaétan Glauser
No abstract text is available yet for this article.
April 25, 2018: Chimia
https://www.readbyqxmd.com/read/29718499/lethal-and-sublethal-effects-of-clothianidin-on-the-development-and-reproduction-of-bemisia-tabaci-hemiptera-aleyrodidae-med-and-meam1
#13
Yong Fang, Jinda Wang, Chen Luo, Ran Wang
The Bemisia tabaci (Gennadius) cryptic species complex includes important crop pests, and among them, the cryptic species Mediterranean (MED) and Middle East-Asia Minor 1 (MEAM1) cause substantial crop losses in China. The second-generation neonicotinoid clothianidin acts as an agonist of the nicotinic acetylcholine receptor in the insect nervous system and has both stomach and contact activity. In this study, the toxicity of clothianidin and five other insecticides to MED and MEAM1 was examined. The sublethal effects of clothianidin on the development and reproduction of MED and MEAM1 were also investigated...
March 1, 2018: Journal of Insect Science
https://www.readbyqxmd.com/read/29717389/calibration-and-validation-of-toxicokinetic-toxicodynamic-models-for-three-neonicotinoids-and-some-aquatic-macroinvertebrates
#14
Andreas Focks, Dick Belgers, Marie-Claire Boerwinkel, Laura Buijse, Ivo Roessink, Paul J Van den Brink
Exposure patterns in ecotoxicological experiments often do not match the exposure profiles for which a risk assessment needs to be performed. This limitation can be overcome by using toxicokinetic-toxicodynamic (TKTD) models for the prediction of effects under time-variable exposure. For the use of TKTD models in the environmental risk assessment of chemicals, it is required to calibrate and validate the model for specific compound-species combinations. In this study, the survival of macroinvertebrates after exposure to the neonicotinoid insecticide was modelled using TKTD models from the General Unified Threshold models of Survival (GUTS) framework...
May 1, 2018: Ecotoxicology
https://www.readbyqxmd.com/read/29710604/inputs-source-apportionment-and-transboundary-transport-of-pesticides-and-other-polar-organic-contaminants-along-the-lower-red-river-manitoba-canada
#15
Jonathan K Challis, Leah D Cuscito, Shira Joudan, Kim H Luong, Charles W Knapp, Mark L Hanson, Charles S Wong
The Red River originates in the U.S., drains into Lake Winnipeg, and is a significant pathway for nutrients. We investigate its role as a source for pesticides, pharmaceuticals, per- and polyfluoroalkyl substances (PFASs), and microbes bearing antibiotic resistance genes (ARGs). We delineate agricultural, urban, and rural land-use for organic contaminants to determine the extent of chemical transboundary riverine fluxes, and characterize levels and trends of organic contaminants and ARGs between spring and fall 2014 and 2015...
April 20, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29709859/gill-bioenergetics-dysfunction-and-oxidative-damage-induced-by-thiamethoxam-exposure-as-relevant-toxicological-mechanisms-in-freshwater-silver-catfish-rhamdia-quelen
#16
Matheus D Baldissera, Carine F Souza, Débora Seben, Letícia R Sippert, Joseania Salbego, Enio Marchesan, Renato Zanella, Bernardo Baldisserotto, Jaqueline I Golombieski
Thiamethoxam is a neonicotinoid pesticide utilized on a worldwide scale, it has been reported in freshwater ecosystems, and detected in fishery products. Nevertheless, there is a lack of information about thiamethoxam sublethal effects on the gills of freshwater fish, principally linked to energetic metabolism. In this context, creatine kinase (CK) is an enzyme of the phosphoryl transfer network that provides a temporal and spatial energy buffer to maintain cellular energy homeostasis in tissues with high energy requirements, such as gills...
April 27, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29705858/fluorometric-aptasensing-of-the-neonicotinoid-insecticide-acetamiprid-by-using-multiple-complementary-strands-and-gold-nanoparticles
#17
Amirhossein Bahreyni, Rezvan Yazdian-Robati, Mohammad Ramezani, Khalil Abnous, Seyed Mohammad Taghdisi
A fluorometric aptamer-based assay was developed for ultrasensitive and selective determination of the neonicotinoid insecticide acetamiprid. The method is based on the use of an aptamer against acetamiprid, multiple complementary strands (CSs), and gold nanoparticles (AuNPs). It is found that by using different CSs, the sensitivity and selectivity of the method is enhanced. On addition of acetamiprid to the aptamer, they will bind to each other and CS1-fluorescein (FAM)-labeled CS2 (as a dsDNA) will be formed...
April 29, 2018: Mikrochimica Acta
https://www.readbyqxmd.com/read/29704179/neonicotinoid-detection-in-wild-turkeys-meleagris-gallopavo-silvestris-in-ontario-canada
#18
Amanda M MacDonald, Claire M Jardine, Philippe J Thomas, Nicole M Nemeth
The use of neonicotinoid insecticides in agriculture is now recognized for the health risks it poses to non-target wildlife, with associated honey bee mortality especially concerning. Research directed toward the presence and effects of these pesticides on terrestrial vertebrates that consume neonicotinoid-coated seeds, such as wild turkeys (Meleagris gallopavo silvestris), is lacking. This study used liquid chromatography attached to a tandem mass spectrometer to assess the liver from 40 wild turkeys for neonicotinoid and other pesticide residues and compared detected levels of these contaminants across the southern Ontario, Canada...
April 27, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29704031/rapid-detection-of-the-neonicotinoid-insecticide-imidacloprid-using-a-quenchbody-assay
#19
Shitao Zhao, Jinhua Dong, Hee-Jin Jeong, Koichi Okumura, Hiroshi Ueda
Contamination of the land and water by neonicotinoid insecticide residues is currently a severe environmental problem. However, the traditional methods for pesticide residue analysis are time consuming and laborious. To tackle this problem, here we describe a novel quenchbody (Q-body) immunoassay reagent that allows the rapid and sensitive detection of imidacloprid, one of the most frequently used neonicotinoid pesticides, in aqueous solution. A Q-body comprises an antibody Fab fragment that is site-specifically labeled with a fluorescent dye...
April 28, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29701941/effects-of-neonicotinoid-pesticides-on-promoter-specific-aromatase-cyp19-expression-in-hs578t-breast-cancer-cells-and-the-role-of-the-vegf-pathway
#20
Élyse Caron-Beaudoin, Rachel Viau, J Thomas Sanderson
BACKGROUND: Aromatase (CYP19) is a key enzyme in estrogens biosynthesis. In the mammary gland, CYP19 gene is expressed at low levels under the regulation of its I.4 promoter. In hormone-dependent breast cancer, fibroblast cells surrounding the tumor express increased levels of CYP19 mRNA due to a decrease of I.4 promoter activity and an increase of PII, I.3, and I.7 promoter activity. Little is known about the effects of environmental chemicals on the promoter-specific CYP19 expression...
April 26, 2018: Environmental Health Perspectives
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