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https://www.readbyqxmd.com/read/28535632/-short-term-effects-of-fine-particulate-matter-exposure-on-pulmonary-function-in-healthy-young-adults-a-time-series-study
#1
Q Yu, J P Liao, Y Hu, X Y Li, C Zhang, X L Li, C L Que, G F Wang
Objective: To explore the short-term effects of fine particulate matter (PM2.5) exposure on pulmonary function of healthy young adults in Beijing. Methods: In this time series study, twenty-four healthy young adults who living around Guanyuan area were investigated in Beijing. The follow-up study was lasted for 12 days in total from Nov. 28, 2016 to Dec. 9, 2016, and pulmonary spirometry and inpulse oscillometry parameters were measured daily. Air pollution data (including PM2.5, etc.) and meteorological data (temperature, humidity, etc...
May 16, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28535594/industrial-pm2-5-cause-pulmonary-adverse-effect-through-rhoa-rock-pathway
#2
Junyan Yan, Chia-Hsiang Lai, Shih-Chun Candice Lung, Chongjun Chen, Wen-Cheng Wang, Pin-I Huang, Chia-Hua Lin
According to the Chinese Ministry of Health, industrial pollution-induced health impacts have been the leading cause of death in China. While industrial fine particulate matter (PM2.5) is associated with adverse health effects, the major action mechanisms of different compositions of PM2.5 are currently unclear. In this study, we treated normal human lung epithelial BEAS-2B cells with industrial organic and water-soluble PM2.5 extracts under daily alveolar deposition dose to elucidate the molecular mechanisms underlying adverse pulmonary effects induced by PM2...
May 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28535462/pharmaceutical-substances-in-ambient-particulates-a-preliminary-assessment
#3
Angelo Cecinato, Paola Romagnoli, Mattia Perilli, Catia Balducci
Till now, no attention has been paid to pharmaceuticals (PCs) in the air, though they are known to affect waters, soils, foods and biota. This paper describes the first attempt to characterize the PC occurrence in the air. Airborne particulates (PM10 or PM2.5 fractions, from Amsterdam, Netherland, Rome and Rende, Italy) were sampled on quartz fiber filter by means of pumping systems operating at medium-volume conditions (16 or 38.5 L min(-1)). The samples were solvent extracted through sonication with a dichloromethane:acetone:methanol mixture and reduced close to dryness; three fractions of the residue were separated through column chromatography; they comprised non polar, low polar and very polar organic compounds, respectively, and PCs were in the third one...
May 18, 2017: Chemosphere
https://www.readbyqxmd.com/read/28534414/estimating-pm2-5-concentrations-in-the-conterminous-united-states-using-the-random-forest-approach
#4
Xuefei Hu, Jessica Hartmann Belle, Xia Meng, Avani Wildani, Lance Waller, Matthew Strickland, Yang Liu
To estimate PM2.5 concentrations, many parametric regression models have been developed, while non-parametric machine learning algorithms are used less often and national-scale models are rare. In this paper, we develop a random forest model incorporating Aerosol Optical Depth (AOD) data, meteorological fields, and land use variables to estimate daily 24-hour averaged ground level PM2.5 concentrations over the conterminous United States in 2011. Random forests are an ensemble learning method that provides predictions with high accuracy and interpretability...
May 23, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28531151/an-ensemble-spatiotemporal-model-for-predicting-pm2-5-concentrations
#5
Lianfa Li, Jiehao Zhang, Wenyang Qiu, Jinfeng Wang, Ying Fang
Although fine particulate matter with a diameter of <2.5 μm (PM2.5) has a greater negative impact on human health than particulate matter with a diameter of <10 μm (PM10), measurements of PM2.5 have only recently been performed, and the spatial coverage of these measurements is limited. Comprehensively assessing PM2.5 pollution levels and the cumulative health effects is difficult because PM2.5 monitoring data for prior time periods and certain regions are not available. In this paper, we propose a promising approach for robustly predicting PM2...
May 22, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28527324/source-characterization-of-urban-particles-from-meat-smoking-activities-in-chongqing-china-using-single-particle-aerosol-mass-spectrometry
#6
Yang Chen, John C Wenger, Fumo Yang, Junji Cao, Rujin Huang, Guangming Shi, Shumin Zhang, Mi Tian, Huanbo Wang
A Single Particle Aerosol Mass Spectrometer (SPAMS) was deployed in the urban area of Chongqing to characterize the particles present during a severe particulate pollution event that occurred in winter 2014-2015. The measurements were made at a time when residents engaged in traditional outdoor meat smoking activities to preserve meat before the Chinese Spring Festival. The measurement period was predominantly characterized by stagnant weather conditions, highly elevated levels of PM2.5, and low visibility...
May 17, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28527212/apolipoprotein-e4-gender-body-mass-index-inflammation-insulin-resistance-and-air-pollution-interactions-recipe-for-alzheimer-s-disease-development-in-mexico-city-young-females
#7
Lilian Calderón-Garcidueñas, Suzanne M de la Monte
Given the epidemiological trends of increasing Alzheimer's disease (AD) and growing evidence that exposure and lifestyle factors contribute to AD risk and pathogenesis, attention should be paid to variables such as air pollution, in order to reduce rates of cognitive decline and dementia. Exposure to fine particulate matter (PM2.5) and ozone (O3) above the US EPA standards is associated with AD risk. Mexico City children experienced pre- and postnatal high exposures to PM2.5, O3, combustion-derived iron-rich nanoparticles, metals, polycyclic aromatic hydrocarbons, and endotoxins...
May 17, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28525860/a-comparison-of-individual-exposure-perception-and-acceptable-levels-of-pm2-5-with-air-pollution-policy-objectives-in-china
#8
Lei Huang, Chao Rao, Tsering Jan van der Kuijp, Jun Bi, Yang Liu
Atmospheric pollution has emerged as a major public health issue in China. Public perception and acceptable risk levels of air pollution can prompt individual behavioral changes and play a major role in the public's response to health risks. Therefore, to explore these responses and evaluate what constitutes publicly acceptable concentrations of fine particulate matter (PM2.5), questionnaire surveys were conducted in three representative cities of China: Beijing, Nanjing, and Guangzhou. Great differences in public risk perception were revealed...
May 16, 2017: Environmental Research
https://www.readbyqxmd.com/read/28525857/industrial-air-emissions-and-proximity-to-major-industrial-emitters-are-associated-with-anti-citrullinated-protein-antibodies
#9
Sasha Bernatsky, Audrey Smargiassi, Lawrence Joseph, Phillip Awadalla, Ines Colmegna, Marie Hudson, Marvin J Fritzler
OBJECTIVE: To determine the association of anti-citrullinated antibodies (ACPA) with the ambient air pollutants fine particulate matter (PM2.5) and sulfur dioxide (SO2). METHODS: The CARTaGENE first-wave cohort includes 20,000 general population subjects from Quebec (Canada). On a sample of unselected 1586 subjects, we determined serum, ACPA and performed multivariable logistic regression, for the outcome of positive ACPA, assessing for independent effects of our air pollution variables, adjusting for age, sex, smoking, and French Canadian origin...
May 16, 2017: Environmental Research
https://www.readbyqxmd.com/read/28525551/who-among-the-elderly-is-most-vulnerable-to-exposure-and-health-risks-of-pm2-5-from-wildfire-smoke
#10
Jia Coco Liu, Ander Wilson, Loretta J Mickley, Keita Ebisu, Melissa P Sulprizio, Yun Wang, Roger D Peng, Xu Yue, Francesca Dominici, Michelle L Bell
Wildfires burn over 7 million US acres annually, according to the US Forest Service. Little is known regarding which subpopulations are more vulnerable to health risks from wildfire smoke, including fine particles. We estimated exposure to fine particles specifically from wildfires and associations between wildfire-specific fine particles and respiratory hospital admissions for subpopulations > 65 years in the Western US (2004-2009). Higher fractions of Blacks and people in urban counties and in California are exposed to > 1 smoke wave (high-pollution episodes from wildfire smoke) compared to other populations...
May 19, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28524038/-intervention-effect-of-qingzao-runfei-huazhuo-xingxue-decoction-on-pm2-5-induced-pulmonary-injury-in-mice
#11
Jinbo Zhang, Lei Zhang, Yanxia Chen, Xinlu Wang, Aihua Hou, Lingling Dai
OBJECTIVE: To study the effects of Qingzao Runfei Huazhuo Xingxue decoction (QRHXD) on inflammatory reaction and histopathology in mice with PM2.5-induced pulmonary injury, and to approach the possible mechanism of prevention and treatment of traditional Chinese medicine on lung injury induced by haze. METHODS: Fifty healthy male C57BL/6 mice were randomly divided into five groups (n = 10): namely control, PM2.5, PM2.5 + low-, moderate-, and high-dose groups. The PM2...
May 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28521450/atmospheric-particulate-matter2-5-promotes-the-migration-and-invasion-of-hepatocellular-carcinoma-cells
#12
Qian Zhang, Qiong Luo, Xueyu Yuan, Li Chai, Dan Li, Jianjun Liu, Zhongwei Lv
Epidemiological data has demonstrated that particulate matter (PM) with an aerodynamic diameter ≤ 2.5 µm (PM2.5) is associated with cancer incidence. However, the precise mechanisms underlying PM2.5-mediated hepatocellular carcinoma cancer (HCC) migration and invasion remain unclear. The aim of the present study was to explore the response of the HCC cell lines HepG2 and HuH-7 to PM2.5 exposure. The results revealed that PM2.5 treatment promoted the migration and invasion of HCC cells, in addition to increasing protein levels of matrix metalloproteinase (MMP)-13...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28521192/long-term-exposure-to-residential-ambient-fine-and-coarse-particulate-matter-and-incident-hypertension-in-post-menopausal-women
#13
Trenton Honda, Melissa N Eliot, Charles B Eaton, Eric Whitsel, James D Stewart, Lina Mu, Helen Suh, Adam Szpiro, Joel D Kaufman, Sverre Vedal, Gregory A Wellenius
BACKGROUND: Long-term exposure to ambient particulate matter (PM) has been previously linked with higher risk of cardiovascular events. This association may be mediated, at least partly, by increasing the risk of incident hypertension, a key determinant of cardiovascular risk. However, whether long-term exposure to PM is associated with incident hypertension remains unclear. METHODS: Using national geostatistical models incorporating geographic covariates and spatial smoothing, we estimated annual average concentrations of residential fine (PM2...
May 15, 2017: Environment International
https://www.readbyqxmd.com/read/28516280/optimization-of-an-ultrasound-assisted-derivatization-for-gc-ms-analysis-of-oxygenated-organic-species-in-atmospheric-aerosol
#14
Maria Chiara Pietrogrande, Francesco Manarini, José Benito Quintana, Rosario Rodil, Eugenia Villaverde-de-Sáa, Marco Visentin
A novel ultrasound-assisted derivatization followed by GC/MS analysis was developed for the quantification of oxygenated organic species in ambient aerosol. Derivatization parameters mostly influencing the analytical response were investigated, i.e., solvent type, reagent concentration, and reaction duration. Response surface methodology was used to design experiments and a quadratic model was utilized to predict the variables and establish the optimal conditions. The study was performed on standard solutions of 30 compounds representing the major classes of oxygenated compounds typically found in ambient aerosol, i...
May 18, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28513752/comparison-of-pm2-5-carbonaceous-pollutants-between-an-urban-site-in-shanghai-and-a-background-site-in-a-coastal-east-china-sea-island-in-summer-concentration-composition-and-sources
#15
Fengwen Wang, Tian Lin, Yuanyuan Li, Zhigang Guo, Neil L Rose
Nine paired samples of atmospheric particulate matter with an aerodynamic diameter less than or equal to 2.5 μm (PM2.5) were collected concurrently from an urban site in Shanghai, China and a background site in Huaniao Island (HNI) in the coastal East China Sea (ECS) between July 21 and 29, 2011. The samples were analyzed for 16 United States Environmental Protection Agency (USEPA) priority polycyclic aromatic hydrocarbons (PAHs), n-alkanes (20 species, C14-C33), hopanes (10 species, C29-C32), and steranes (12 species, C27-C29)...
May 17, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28512061/genetic-variants-in-autophagy-associated-genes-are-associated-with-dna-damage-levels-in-chinese-population
#16
Zhihua Li, Junyi Xin, Weihong Chen, Jia Liu, Meng Zhu, Congwen Zhao, Jing Yuan, Guangfu Jin, Hongxia Ma, Jiangbo Du, Zhibin Hu, Tangchun Wu, Hongbing Shen, Juncheng Dai, Hao Yu
Autophagy associated genes (ATGs) played an important role in the repair process of DNA damage and decreased autophagy may weaken the repair process and aggravate DNA damage. Based on this, we hypothesized that DNA damage levels might be modified by genetic variants in autophagy associated genes. In order to validate our hypothesis, 307 subjects were recruited from three different cities (Zhuhai, Wuhan and Tianjin) in China. Demographic data, individual 24-h PM2.5 exposure and peripheral blood DNA damage levels were also detected...
May 13, 2017: Gene
https://www.readbyqxmd.com/read/28511647/low-smoke-chulha-in-indian-slums-study-protocol-for-a-randomised-controlled-trial
#17
Megha Thakur, Esther A Boudewijns, Giridhara R Babu, Bjorn Winkens, Luc P de Witte, Jeroen Gruiskens, Preeti Sushama, Cristian T Ghergu, Onno C P van Schayck
BACKGROUND: Biomass fuel is used as a primary cooking source by more than half of the world's population, contributing to a high burden of disease. Although cleaner fuels are available, some households continue using solid fuels because of financial constraints and absence of infrastructure, especially in non-notified slums. The present study documents a randomised controlled study investigating the efficacy of improved cookstove on the personal exposure to air pollution and the respiratory health of women and children in an Indian slum...
May 16, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28511360/refined-2013-based-vehicle-emission-inventory-and-its-spatial-and-temporal-characteristics-in-zhengzhou-china
#18
Mimi Gong, Shasha Yin, Xingke Gu, Yuanqian Xu, Nan Jiang, Ruiqin Zhang
Vehicle emission is becoming one of the most important pollution sources because of the increase in vehicle population and activity in China. A more reasonable and complete vehicle emission inventory in Zhengzhou for the year 2013 was developed in this study. This inventory is suitable for local emission factors and vehicle kilometers of travel. Estimates show that the total carbon monoxide (CO), hydrocarbon (HC), nitrogen oxide (NOX), particulate matter (PM2.5 and PM10) and sulfur dioxide (SO2) emissions were 291Gg, 35Gg, 106Gg, 6Gg, 7Gg, and 3Gg, respectively...
May 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28511038/attributable-risks-of-emergency-hospital-visits-due-to-air-pollutants-in-china-a-multi-city-study
#19
Gongbo Chen, Yongming Zhang, Wenyi Zhang, Shanshan Li, Gail Williams, Guy B Marks, Bin Jalaludin, Michael J Abramson, Fengming Luo, Dong Yang, Xin Su, Qichang Lin, Laiyu Liu, Jiangtao Lin, Yuming Guo
Air pollution is associated with risks of mortality in China, but the evidence is still limited for morbidity. This study aims to examine overall effects of ambient air pollutants on emergency hospital visits (EHVs) at the national level in China and calculate corresponding attributable risks. We collected daily data for EHVs from 33 largest hospitals in China between Oct 2013 and Dec 2014, as well as daily measurements of particulate matter (PM10 and PM2.5: particles with aerodynamic diameter < 10 μm and 2...
May 13, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28510106/the-pollution-characteristics-of-pm2-5-and-correlation-analysis-with-meteorological-parameters-in-xinxiang-during-the-shanghai-cooperation-organization-prime-ministers-meeting
#20
Jinglan Feng, Hao Yu, Kai Mi, Xianfa Su, Yunqi Chen, Jian-Hui Sun, Qilu Li
The pollution characteristics of PM2.5 and correlation analysis with meteorological parameters in Xinxiang during the Shanghai Cooperation Organization Prime Ministers' Meeting were investigated. During the whole meeting, nine PM2.5 samples were collected at a suburban site of Xinxiang, and the average concentration of PM2.5 was 122.28 μg m(-3). NO3(-), NH4(+), SO4(2-) accounted for 56.8% of the total water-soluble ions. In addition, with an exception of Cl(-), all of water-soluble ions decreased during the meeting...
May 16, 2017: Environmental Geochemistry and Health
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