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Parathyroid surgery

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https://www.readbyqxmd.com/read/28630836/teriparatide-treatment-improved-loosening-of-cementless-total-knee-arthroplasty-a-case-report
#1
Takashi Suzuki, Keinosuke Ryu, Kei Kojima, Shu Saito, Hiroshi Nagaoka, Yasuaki Tokuhashi
INTRODUCTION: Along with the increase of osteoporotic patients in an aging society, complications in surgeries associated with osteoporosis are also increasing. In cementless total knee arthroplasty (TKA), poor primary stability and subsequent initial loosening of the implant may be seen. CASE REPORT: The patient, a 75-year-old Asian woman with a history of osteoporosis, underwent cementless TKA. Knee radiography at 5 weeks postoperatively showed radiolucent lines outlined beneath the tibial tray and around the stem...
January 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28624166/retrograde-thyroidectomy-for-preservation-of-the-external-branch-of-the-superior-laryngeal-nerve-a-case-series
#2
Vijay Naraynsingh, Shamir Cawich, Dale Hassranah, Ravi Maharaj, Shariful Islam, Yardesh Singh
BACKGROUND: The external branch of the Superior Laryngeal nerve (EBSLN) is at high risk of injury in surgery for large multinodular goitre (MNG) since the upper pole is high in the neck, well cephalad to the EBSLN. We present a technique of drawing the lobe caudally by retrograde thyroidectomy in order to minimize nerve injury. DESIGN & METHOD: All patients having surgery for benign MNG were included. Cases with previous thyroid surgery, malignant and toxic disease were excluded...
May 15, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28614027/parathyroid-surgery-from-inception-to-the-modern-day
#3
Neeraj Sethi, R James A England
Parathyroid surgery has undergone great changes since its inception less than a century ago. It is still the only definitive option available to cure primary or tertiary hyperparathyroidism. This review details the development of parathyroid surgery, our understanding of hyperparathyroidism and the treatment options available. It also discusses the technological advances that have enabled parathyroid localization and prediction of surgical success.
June 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28589571/laparoscopic-total-pancreatectomy-for-multiple-endocrine-neoplasia-type-1-syndrome-associated-multifocal-non-functioning-pancreatic-neuroendocrine-tumor-a-case-report
#4
Palanisamy Senthinathan, Samrat Vijaykumar Jankar, Sandeep C Sabnis, Vivek Kaje, Sivakumar Srivatsan Gurumurthy, Natesan Anand Vijai, Vaiyapurigounder Palanisamy Nalankilli, Palanivelu Praveen Raj, Ramakrishanan Parthasarathi, Subbiah Rajapandian, Chinnusamy Palanivelu
Pancreatic neuroendocrine tumors are rare, accounting for less than 3% of all pancreatic tumors. Although laparoscopic pancreas-preserving surgery for managing sporadic pancreatic neuroendocrine tumors has been described in the literature, laparoscopic total pancreatectomy has rarely been reported. We present a 30-year-old man who was incidentally diagnosed with multiple endocrine neoplasia type 1 syndrome with parathyroid hyperplasia and a non-functioning pancreatic neuroendocrine tumor. He underwent laparoscopic total pancreatectomy with splenectomy...
June 6, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28589529/dietary-intake-and-weight-changes-5%C3%A2-years-after-laparoscopic-sleeve-gastrectomy
#5
Ju-Jun Chou, Wei-Jei Lee, Owaid Almalki, Jung-Chien Chen, Pei-Ling Tsai, Shwu-Huey Yang
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is becoming a leading primary bariatric surgery but long-term outcome remains unclear. The amount of food eaten is drastically reduced after LSG and may lead to nutritional deficiencies potentially. The aim of this study is to investigate long-term dietary intake and weight status after LSG. METHODS: Forty patients underwent LSG had more than 5-year follow-up with complete clinical data and food frequency questionnaires were analyzed...
June 6, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28588170/early-postoperative-parathyroid-hormone-level-as-a-predictor-of-hypocalcaemia-after-total-thyroidectomy
#6
S B Sharif, S A Rakib, K S Naznin, S M Alam
Postoperative transient hypocalcaemia is a common squeal after total thyroidectomy usually due to parathyroid insufficiency. Objective of this study is to find out the optimum cut-off value of parathyroid hormone (PTH) level in early postoperative period as a best predictor for hypocalcaemia. This prospective observational study was carried out from July 2013 to July 2014 in the Department of Surgery Sir Salimullah Medical College & Mitford Hospital (SSMC&MH), in collaboration with department of Otolaryngology SSMC&MH, department of Otolaryngology Bangabandhu Sheikh Mujib Medical University (BSMMU) and department of Otolaryngology Dhaka Medical College & Hospital (DMC&H), Dhaka...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28585593/incidentaloma-from-general-practice-to-specific-endocrine-frame
#7
Ancuta Augustina Gheorghisan-Galateanu, Mara Carsote, Ana Valea
Incidentaloma, a modern concept connected to technology progress, represents an accidentally discovered tumour, usually used for hypophysis and adrenals, and rarely for thyroid, parathyroids, and ovaries. This is a narrative review based on PubMed research, between 2012 and 2016 focusing on general and endocrine approach and current controversies. Main dilemma is the terminology itself: randomly imagery finding is enough or non-functioning profile and low-growth rate (not requiring surgery) should be mandatory? The controversies refers to best time framing of re-scanning pituitary and adrenal incidentaloma and setting of clear criteria for subclinical Cushing's syndrome...
June 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28584743/benign-and-malignant-thyroid-gland-diseases-in-the-patients-with-primary-hyperparathyroidism
#8
Mehmet Celik, Sibel Guldiken, Semra Ayturk, Buket Yilmaz Bulbul, Ebru Tastekin, Nuray Can, Atakan Sezer, Funda Ustun, Ahmet Kucukarda
INTRODUCTION: This study aimed to evaluate concurrently detected thyroid pathologies in the patients who underwent surgery for primary hyperparathyroidism (PHPT). MATERIALS AND METHODS: In this study, we retrospectively analyzed the files of the patients who underwent surgery for PHPT between 2012 and 2015. Pre- and post-operative laboratory examination results and preoperative radiological and nuclear medicine findings of the patients were retrospectively recorded...
April 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28580385/modeling-and-remodeling-effects-of-intermittent-administration-of-teriparatide-parathyroid-hormone-1-34-on-bone-morphogenetic-protein-induced-bone-in-a-rat-spinal-fusion-model
#9
Takashi Kaito, Tokimitsu Morimoto, Sadaaki Kanayama, Satoru Otsuru, Masafumi Kashii, Takahiro Makino, Kazuma Kitaguchi, Masayuki Furuya, Ryota Chijimatsu, Kosuke Ebina, Hideki Yoshikawa
BACKGROUND: Bone morphogenetic protein (BMP)-based tissue engineering has focused on inducing new bone efficiently. However, modeling and remodeling of BMP-induced bone have rarely been discussed. Teriparatide (parathyroid hormone [PTH] 1-34) administration initially increases markers of bone formation, followed by an increase in bone resorption markers. This unique activity would be expected to accelerate the modeling and remodeling of new BMP-induced bone. METHODS: Male Sprague-Dawley rats underwent posterolateral spinal fusion surgery and implantation of collagen sponge containing either 50 μg recombinant human (rh)BMP-2 or saline...
December 2016: Bone Reports
https://www.readbyqxmd.com/read/28578084/a-novel-surgical-strategy-for-secondary-hyperparathyroidism-purge-parathyroidectomy
#10
Cheng-Xiang Shan, Nian-Cun Qiu, Si-Luo Zha, Miao-E Liu, Qiang Wang, Pei-Pei Zhu, Zhi-Peng Du, Chun-Yan Xia, Ming Qiu, Wei Zhang
OBJECTIVE: This study was intended to demonstrate the feasibility and efficacy of purge parathyroidectomy (PPTX) for patients with secondary hyperparathyroidism (SHPT). METHODS: The "seed, environment, and soil" medical hypothesis was first raised, following review of the literatures, to demonstrate the possible causes of persistence or recurrence of SHPT after parathyroidectomy. Subsequently, the novel surgical strategy of PPTX was proposed, which involves comprehensive resection of the fibro-fatty tissues, including visible or invisible parathyroid, within the region surrounded by the thyroid cartilage, bilateral carotid artery sheath, and the brachiocephalic artery...
May 31, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28571792/papillary-carcinoma-of-the-thyroid-in-patients-with-primary-hyperparathyroidism-is-there-a-link
#11
M Beebeejaun, E Chinnasamy, P Wilson, A Sharma, N Beharry, G Bano
Primary hyperparathyroidism (PHPT) is present in up to 0.1% of the general population. The incidence is higher in women and increases with age. The majority of the cases is asymptomatic and up to 85% are due to single gland adenoma. Parathyroidectomy is the treatment of choice after localization of the hyperactive gland. Papillary Thyroid Carcinoma (PTC) is the most common cancer of the thyroid and constitutes more than 70% of thyroid malignancies. PTC can present as a single nodule or can be Multifocal. The incidence is higher in women...
June 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28569362/can-arfi-elastography-be-used-to-differentiate-parathyroid-from-thyroid-lesions
#12
A Chandramohan, M Therese, D Abhraham, T V Paul, P Jacob Mazhuvanchary
OBJECTIVES: To assess if elasticity score (ES) and shear wave velocity (SWV) measurement obtained using ARFI elastography can differentiate between parathyroid lesions and thyroid nodules. MATERIALS AND METHODS: ARFI elastography was performed on patients with primary hyperparathyroidism or solid thyroid nodules who were being considered for surgery using virtual touch quantification and virtual touch imaging (VTI) software. Only patients with surgical histopathology (47 parathyroid lesions, 38 benign thyroid nodules and 55 malignant thyroid nodules) were included for final analysis...
May 31, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28569356/effects-of-laparoscopic-sleeve-gastrectomy-on-parathyroid-hormone-vitamin-d-calcium-phosphorus-and-albumin%C3%A2-levels
#13
Mehmet Mihmanli, Riza Gurhan Isil, Canan Tulay Isil, Sinan Omeroglu, Pinar Sayin, Sibel Oba, Feyza Yener Ozturk, Yuksel Altuntas
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) reduces obesity-related co-morbidities, such as diabetes, hypertension, and hyperlipidemia. Endocrinological abnormalities may occur as undesired side effects. Most centers routinely prescribe folic acid, cyanocobalamin (vitB12), and protein replacement in the postoperative period, but 25-OH-vitamin-D3 (vitD) and intact parathyroid hormone (iPTH) levels are not routinely followed up. The aim of this study was to identify the effects of LSG on iPTH, vitD, calcium (Ca), phosphorus (P), alkaline phosphatase (ALP), and albumin levels...
May 31, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28566413/hypercalcaemic-encephalopathy-due-to-metastatic-parathyroid-carcinoma
#14
Dhalapathy Sadacharan, Shriraam Mahadevan, Jabamalai Ferdinant, Kaharin Rakeshchandru
A 49-year-old man presented in the emergency department with altered sensorium and renal failure and was placed on a ventilator. Evaluation with MRI of the brain showed enhancing lesion in the occipital lobe. Biochemical tests revealed elevated calcium and parathyroid hormone (PTH) levels. Further evaluation revealed multiple lesions at both lobes of the lungs and nodular lesion in the right inferior pole of the thyroid. Diagnosis of metastatic parathyroid carcinoma was suspected. Patient was stabilised with bisphosphonates and haemodialysis and planned for surgery...
May 31, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28559945/sensitive-detection-of-a-small-parathyroid-adenoma-using-fluorocholine-pet-ct-a-case-report
#15
Thanseer N T K Padinhare-Keloth, Sanjay K Bhadada, Ashwani Sood, Rajender Kumar, Arunanshu Behera, Bishan D Radotra, Bhagwant R Mittal
Primary hyperparathyroidism is caused by parathyroid adenoma in the majority of cases and diagnosis is usually made biochemically. Pre-surgical localization of parathyroid adenoma is essential to limit the extent of surgery and avoid missing them at ectopic sites. Anatomical and functional imaging are used for the localization, but may fail to identify the small and ectopic parathyroid adenoma. We present a case of small sized ectopic parathyroid adenoma at unusual location detected by F-18 fluorocholine (FCH) PET/CT, where other imaging modalities failed...
June 2017: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28553700/minimally-invasive-radioguided-parathyroid-surgery-using-low-dose-tc-99m-mibi-comparison-with-standard-high-dose
#16
Ali Jangjoo, Ramin Sadeghi, Zohreh Mousavi, Masoud Mohebbi, Mahtab Khaje, Mehdi Asadi
BACKGROUND: Surgery remains the most effective treatment for primary hyperparathyroidism (PHPT). Minimally invasive radioguided parathyroidectomy (MIRP) is a common technique for detecting and excising abnormal parathyroid glands. The aim of this study was to compare injections of low-dose and high-dose (99m) Tc methoxy isobutyl isonitrile (MIBI) for intraoperative localisation of parathyroid adenomas by means of a gamma probe in patients with primary hyperparathyroidism (PHPT). MATERIAL AND METHODS: Thirty patients with PHPT and a preoperative diagnosis of parathyroid adenoma were enrolled between 2010 and 2012...
May 29, 2017: Endokrynologia Polska
https://www.readbyqxmd.com/read/28553182/ultrastructure-of-hyperfunctioning-parathyroid-glands-does-it-explain-various-patterns-of-99m-tc-sestamibi-uptake
#17
Abdelhamid H Elgazzar, Jehoran T Anim, Shorouk F Dannoon, Medhat M Farghaly
The aim of this study was to correlate the uptake of (99m)Tc-methoxy-isobutyl-isonitrile (MIBI) with ultra-structural features of parathyroid adenomas. Twenty patients with proven primary hyperparathyroidism were evaluated prospectively. Preoperative double-phase (99m)Tc-MIBI scintigraphy was performed in all patients and the degree of tracer uptake by the parathyroid lesions was assessed visually and semi-quantitatively. The excised glands were examined histologically and ultrastructurally, and their features were correlated with the degree of the radiotracer uptake...
April 2017: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28551934/-parathyroid-autotransplantation-in-adults-and-children
#18
REVIEW
Michael M Krausz, Itamar Ashkenazi, Ricardo Alfici
The indications and methods of parathyroid autotransplantation in children and adults are reviewed, with special emphasis on the methods of immediate transplantation and delayed autotransplantation after cryopreservation. Parathyroid autotransplantation is performed during surgery when all four parathyroid glands have been intentionally resected in parathyroid hyperplasia, or when all four glands were inadvertently damaged during total thyroidectomy, or recurrent neck surgery. When parathyroid damage is suspected during thyroid or extensive neck surgery, cryopreservation of a parathyroid gland is performed...
March 2017: Harefuah
https://www.readbyqxmd.com/read/28546753/protocol-for-management-after-thyroidectomy-a-retrospective-study-based-on-one-center-experience
#19
Han Luo, Hongliu Yang, Tao Wei, Yanping Gong, Anping Su, Yu Ma, Xiuhe Zou, Jianyong Lei, Wanjun Zhao, Jingqiang Zhu
BACKGROUND AND AIM: The optimal approach to detect and treat symptomatic hypocalcemia (SxH) after thyroidectomy is still uncertain. In our retrospective study, we sought to set a standardized postoperative management protocol on the basis of relative change of parathyroid hormone (PTH) and absolute value of postoperative day 1 (POD1) PTH. METHODS: Patients who underwent thyroidectomy were identified retrospectively in our prospective database. Blood was collected 1 day before surgery and on POD1...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28543268/sensitivity-of-3-dimensional-sonography-in-preoperative-evaluation-of-parathyroid-glands-in-patients-with-primary-hyperparathyroidism
#20
Susan J Frank, Adam E Goldman-Yassen, Tova Koenigsberg, Steven K Libutti, Mordecai Koenigsberg
OBJECTIVES: Preoperative localization of parathyroid adenomas in patients with primary hyperparathyroidism facilitates targeted surgery. We assessed the sensitivity of 3-dimensional (3D) sonography for preoperative localization of abnormal parathyroid glands. METHODS: We conducted a retrospective review of patients who underwent parathyroidectomy for primary hyperparathyroidism at a single site at our institution. We compared preoperative 2-dimensional (2D) sonography, 3D sonography, and sestamibi scans with final gland localization at surgery...
May 24, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
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