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https://www.readbyqxmd.com/read/29470184/impact-of-3d-virtual-planning-on-reconstruction-of-mandibular-and-maxillary-surgical-defects-in-head-and-neck-oncology
#1
Max J H Witjes, Rutger H Schepers, Joep Kraeima
PURPOSE OF REVIEW: This review describes the advances in 3D virtual planning for mandibular and maxillary reconstruction surgical defects with full prosthetic rehabilitation. The primary purpose is to provide an overview of various techniques that apply 3D technology safely in primary and secondary reconstructive cases of patients suffering from head and neck cancer. RECENT FINDINGS: Methods have been developed to overcome the problem of control over the margin during surgery while the crucial decision with regard to resection margin and planning of osteotomies were predetermined by virtual planning...
February 20, 2018: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/29468508/ultrasound-guided-bilateral-superficial-cervical-block-and-preemptive-single-dose-oral-tizanidine-for-post-thyroidectomy-pain-a-randomized-controlled-double-blind-study
#2
Ali Ahiskalioglu, Ahmet Murat Yayik, Elif Oral Ahiskalioglu, Aysenur Dostbil, Omer Doymus, Erdem Karadeniz, Muhammet Ali Ari, Furkan Sengoz, Haci Ahmet Alici, Erkan Cem Celik
PURPOSES: The postoperative analgesic effect of tizanidine has not yet been evaluated sufficiently. The role of bilateral superficial cervical plexus block (BSCPB) for postoperative analgesia after thyroidectomy remains questionable. We aimed to evaluate the analgesic effect of combined use of BSCPB and a single-dose oral tizanidine in patients undergoing elective thyroid surgery. METHODS: Sixty patients undergoing thyroidectomy were randomized into 3 groups. The control group (Group C, n = 20) received BSCPB with 0...
February 21, 2018: Journal of Anesthesia
https://www.readbyqxmd.com/read/29467336/frameshift-events-predict-anti-pd-1-l1-response-in-head-and-neck-cancer
#3
Glenn J Hanna, Patrick Lizotte, Megan Cavanaugh, Frank C Kuo, Priyanka Shivdasani, Alexander Frieden, Nicole G Chau, Jonathan D Schoenfeld, Jochen H Lorch, Ravindra Uppaluri, Laura E MacConaill, Robert I Haddad
Programmed cell death protein 1 (PD-1) inhibitors have efficacy in treating squamous cell carcinoma of the head and neck (SCCHN), but objective response rates are low. PD-1 ligand (PD-L1) expression alone is not considered a robust predictor of response and additional biomarkers are needed. This 3-year observational cohort followed 126 SCCHN patients treated with anti-PD-1/L1 therapy. Prior to treatment, 81 (64%) had targeted massively parallel tumor sequencing. Of these, 42 (52%) underwent fluorescence-activated cell sorting and PD-L1 immunohistochemistry for tumor immunoprofiling...
February 22, 2018: JCI Insight
https://www.readbyqxmd.com/read/29463320/medialisation-thyroplasty-with-tensor-fascia-lata-a-novel-approach-for-reducing-post-thyroplasty-complications
#4
T N Chao, A Mahmoud, K Rajasekaran, N Mirza
BACKGROUND: Medialisation thyroplasty is considered the 'gold standard' treatment for unilateral vocal fold paralysis, enabling improvement of voice and swallowing function, and preventing life-threatening aspiration events. The most commonly used laryngeal implants induce some degree of local tissue inflammatory response, and carry the risk of immediate or delayed implant extrusion. METHODS: This paper describes a novel approach for medialisation thyroplasty. Specifically, it utilises a ribbon of autologous tensor fascia lata harvested at the time of surgery...
February 21, 2018: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/29463113/pediatric-lip-adhesion-following-bullous-erythema-multiforme-and-review-of-similar-oral-complications
#5
Rosalind Ashton, Karen W Wong, Miriam Weinstein
BACKGROUND: Erythema multiforme (EM) is a mucocutaneous disease most often associated with preceding herpes simplex virus or Mycoplasma pneumoniae infection. It is characterized by targetoid lesions occurring on the limbs and head and neck. Mucosal involvement can be extensive. OBJECTIVE: We report a case of lip adhesion as a complication of EM in a child who required corrective surgery and review similar oral commissure complications. METHODS: We completed a review of the literature for similar cases using PubMed and Medline...
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29462828/computer-aided-surgical-simulation-in-head-and-neck-reconstruction-a-cost-comparison-among-traditional-in-house-and-commercial-options
#6
Sean S Li, Libby R Copeland-Halperin, Alexander J Kaminsky, Jihui Li, Fahad K Lodhi, Reza Miraliakbari
BACKGROUND: Computer-aided surgical simulation (CASS) has redefined surgery, improved precision and reduced the reliance on intraoperative trial-and-error manipulations. CASS is provided by third-party services; however, it may be cost-effective for some hospitals to develop in-house programs. This study provides the first cost analysis comparison among traditional (no CASS), commercial CASS, and in-house CASS for head and neck reconstruction. METHODS: The costs of three-dimensional (3D) pre-operative planning for mandibular and maxillary reconstructions were obtained from an in-house CASS program at our large tertiary care hospital in Northern Virginia, as well as a commercial provider (Synthes, Paoli, PA)...
February 20, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29462066/outcomes-of-surgical-decompression-in-patients-with-very-severe-degenerative-cervical-myelopathy
#7
Branko Kopjar, Parker E Bohm, Joshua H Arnold, Michael G Fehlings, Lindsay A Tetreault, Paul M Arnold
STUDY DESIGN: A prospective observational international study. OBJECTIVE: The aim of this study was to evaluate outcomes of decompressive surgery in patients with very severe degenerative cervical myelopathy (DCM). SUMMARY OF BACKGROUND DATA: Although decompressive surgery has been evidenced as a safe and effective approach for patients with myelopathic deficiencies, studies have suggested residual disability following treatment in patients with more severe disease presentation...
February 16, 2018: Spine
https://www.readbyqxmd.com/read/29460670/opioid-prescribing-patterns-among-otolaryngologists
#8
Marissa A Schwartz, James G Naples, Chia-Ling Kuo, Todd E Falcone
Objectives To evaluate national trends in opioid prescribing patterns by otolaryngologists for postoperative pain control after common otolaryngologic procedures. Study Design Cross-sectional; survey. Subjects and Methods A survey to determine opioid prescribing patterns for the treatment of postoperative pain following common otolaryngologic procedures was distributed to all members of the American Academy of Otolaryngology-Head and Neck Surgery. Results The most common pain medication prescribed for adults postoperatively was hydrocodone-acetaminophen (73%), followed by oxycodone-acetaminophen (39%)...
February 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29460178/a-cooperation-of-catheters-and-guidewires-based-novel-remote-controlled-vascular-interventional-robot
#9
Xianqiang Bao, Shuxiang Guo, Nan Xiao, Youxiang Li, Cheng Yang, Yuhua Jiang
Remote-controlled vascular interventional robots (RVIRs) are being developed to increase the overall accuracy of surgical operations and reduce the occupational risks of intervening physicians, such as radiation exposure and chronic neck/back pain. Several RVIRs have been used to operate catheters or guidewires accurately. However, a lack of cooperation between the catheters and guidewires results in the surgeon being unable to complete complex surgery by propelling the catheter/guidewire to the target position...
February 19, 2018: Biomedical Microdevices
https://www.readbyqxmd.com/read/29459595/distribution-management-difficulty-and-outcome-of-branchial-anomalies
#10
M A Sattar, M T Sultana, S Ahmed
Branchial arch anomalies are one of the most common congenital anomalies of the neck. Developmental anomalies of the branchial apparatus account for 17% of all pediatric cervical masses. This study aimed to focus on proper diagnosis of branchial anomaly and describe occurrence, presentation, management and outcome of usual and unusual types. This ten-year prospective observational study was conducted from November 2005 to November 2015 including 2-year postoperative follow-up of the patients in Department of ENT, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh...
January 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29458414/bilateral-internal-jugular-vein-thrombosis-due-to-malignant-tumor
#11
Laura Leci-Tahiri, Harieta Zherka-Saracini, Afrim Tahiri, Adhurim Koshi
BACKGROUND: The aim of the study was to analyze characteristics of patients with bilateral internal jugular vein thrombosis in our department during a 1-year period. Internal jugular vein thrombosis refers to an intraluminal thrombus occurring anywhere from the intracranial internal jugular vein to the junction of the internal jugular vein and the subclavian vein, which form the brachiocephalic vein. It can occur spontaneously or as a complication of head and neck infections, surgery, central venous lines, local malignancy, polycytemia, hyperhomocysteinemia, neck massage, or intravenous drug abuse...
February 20, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29457411/-effect-of-hip-fracture-at-different-sites-in-elderly-patients-on-prognosis
#12
Cheng Peng, Xiao-Wei Wang, Shao-Guang Li, Zhi Liu, Tian-Sheng Sun, Jian-Zheng Zhang
OBJECTIVE: To determine the effect of site of fracture on the prognosis for patients of elderly hip fracture. METHODS: From January 2012 to December 2014, 667 patients with hip fractures were divided into femoral neck fracture group and intertrochanteric fracture group according to the site of fracture. There were 304 cases of intertrochanteric fracture, including 96 males and 208 females, with an average age of (80.33±7.94) years old. There were 217 cases of femoral neck fracture, including 74 males and 143 females, with an average age of (79...
October 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457320/restoration-of-facial-form-and-lip-competence-in-a-patient-with-a-midfacial-defect
#13
Melani Kapetanakos, Sarah Wisniewski, Marjorie Golden, Joseph Randazzo
Squamous cell carcinoma (SCC) of the head and neck can be treated with a combination of modalities. There is an esthetic and functional compromise with midfacial defects secondary to ablative surgery and adjuvant therapies for SCC. Osteoradionecrosis, tissue contracture, and trismus, are all negative side effects of treatment and can impact a patient's function and possibly their nutrition. In this report, we describe a procedure for fabrication of a prosthesis that provides cosmetic improvement and labial competence to maintain caloric intake...
February 18, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29456914/is-cervical-bracing-necessary-after-one-and-two-level-instrumented-anterior-cervical-discectomy-and-fusion-a-prospective-randomized-study
#14
Samuel C Overley, Robert K Merrill, Evan O Baird, Joshua J Meaike, Samuel K Cho, Andrew C Hecht, Sheeraz A Qureshi
Study Design: Prospective randomized control trial. Objective: To investigate the role of cervical collars in postoperative care following 1- and 2-level instrumented anterior cervical discectomy and fusion (ACDF). Methods: The Cervical Spine Research Society Resident Fellow Grant funded this project. Fifty consecutive patients undergoing 1- or 2-level ACDF surgery were randomized into groups receiving either no brace or a cervical brace for 6 weeks postoperatively...
February 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29455630/cervical-endoscopic-spinal-surgery-a-review-of-the-current-literature
#15
Vittoria Bucknall, Jn Alastair Gibson
Cervical endoscopic spinal surgery (CESS) is now regularly performed in some centres in the Far East, yet rarely in Europe and the United States. This review describes the application of CESS through anterior and posterior approaches with analysis of the available evidence supporting current techniques. An electronic literature search identified 52 papers and proceedings' abstracts of which 25 (16 anterior approach and 9 posterior approach) provided comparable clinical outcomes. The results revealed a good or excellent outcome from CESS in 91% (range 74-100%) with a complication rate of 5%...
January 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29455293/variations-of-transverse-foramina-in-cervical-vertebrae-what-happens-to-the-vertebral-artery
#16
Aristeidis Zibis, Vasileios Mitrousias, Nikolaos Galanakis, Nikoletta Chalampalaki, Dimitrios Arvanitis, Apostolos Karantanas
PURPOSE: The purpose of this study is to examine variations of the foramen transversarium and the vertebral artery in computed tomography angiographies (CTa) of the cervical spine, investigate their coexistence, and present possible considerations regarding such variations in spine surgical procedures. METHODS: Fifty CTa of the neck were retrospectively reviewed. Transverse and anteroposterior diameter of the foramen and diameter of the vertebral artery were measured...
February 17, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29453230/role-of-biomarkers-in-predicting-the-occurrence-of-thyroid-neoplasms-in-radiation-exposed-children
#17
Joseph Shulan, Leonid Vydro, Arthur B Schneider, Dan Mihailescu
With increasing numbers of childhood cancer survivors who were treated with radiation, there is a need to evaluate potential biomarkers that could signal an increased risk of developing thyroid cancer. We aimed to examine the relationships between thyrotropin and thyroglobulin levels and the risk of developing thyroid nodules and cancer in a cohort of radiation exposed children. 806 subjects who were irradiated in the neck area as children were examined and followed for up to 25 years. All subjects underwent a clinical examination, measurements of thyrotropin, thyroglobulin levels and thyroid imaging...
February 16, 2018: Endocrine-related Cancer
https://www.readbyqxmd.com/read/29453209/recurrent-epistaxis-leading-to-diagnosis-of-primary-sinonasal-melanoma
#18
Karine Tawagi, Rita Akaraz-Avedissian, Irina Burman-Solovyeva
A 48-year-old man presented to urgent care with recurrent epistaxis over 6 months. Initially, nosebleeds were controlled with packing or cautery. Ultimately, he was referred to ear, nose and throat department and underwent nasal endoscopy which revealed polypoid tissue. A biopsy of the polyp showed non-specific inflammation with no evidence of malignancy. Follow-up maxillofacial CT revealed a large mass lesion in the right maxillary sinus, right nasal fossa, much of the ethmoids and right sphenoid, with destruction of adjacent bony structures...
February 16, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29452973/the-alpha-defensin-test-for-diagnosing-periprosthetic-joint-infection-in-the-setting-of-an-adverse-local-tissue-reaction-secondary-to-a-failed-metal-on-metal-bearing-or-corrosion-at-the-head-neck-junction
#19
Kamil T Okroj, Tyler E Calkins, Erdan Kayupov, Michael M Kheir, Joshua S Bingham, Christopher P Beauchamp, Javad Parvizi, Craig J Della Valle
BACKGROUND: In patients with adverse local tissue reaction (ALTR) secondary to a failed metal-on-metal (MoM) bearing or corrosion at the head-neck junction in a metal-on-polyethylene bearing, ruling in or out periprosthetic joint infection (PJI) can be challenging. Alpha-defensin has emerged as an accurate test for PJI. The purpose of this multicenter, retrospective study was to evaluate the accuracy of the alpha-defensin synovial fluid test in detecting PJI in patients with ALTR. METHODS: We reviewed medical records of 26 patients from 3 centers with ALTR that had an alpha-defensin test performed...
January 16, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29451961/patterns-of-care-and-outcomes-of-adjuvant-therapy-for-high-risk-head-and-neck-cancer-after-surgery
#20
Virginia Wedell Osborn, Babak Givi, Justin Rineer, Dylan Roden, Niki Sheth, Ariel Lederman, Evangelia Katsoulakis, Kenneth Hu, David Schreiber
BACKGROUND: Postoperative chemoradiotherapy (CRT) is considered standard of care in patients with locally advanced head and neck cancer with positive margins and/or extracapsular extension (ECE). METHODS: The National Cancer Data Base (NCDB) was queried to identify patients with squamous cell carcinoma of the head and neck with stages III to IVB disease or with positive margins and/or ECE diagnosed between 2004 and 2012 receiving postoperative radiotherapy (RT)...
February 16, 2018: Head & Neck
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