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https://www.readbyqxmd.com/read/28618202/effects-of-persistent-fontan-fenestration-patency-on-cardiopulmonary-exercise-testing-variables
#1
M Elisabeth Heal, Lanier B Jackson, Andrew M Atz, Ryan J Butts
Cardiopulmonary exercise testing (CPET) aids in clinical assessment of patients with Fontan circulation. Effects of persistent fenestration on CPET variables have not been clearly defined. Associations between fenestration and CPET variables at anaerobic threshold (AT) and peak exercise were explored in the Pediatric Heart Network Fontan Cross-Sectional Study cohort. Fenestration patency was associated with a greater decrease in oxygen saturation from rest to peak exercise (fenestration -4.9 ± 3.8 v. nonfenestration -3 ± 3...
June 15, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28606099/pulmonary-hemodynamics-and-effects-of-phosphodiesterase-type-5-inhibition-in-heart-failure-a-meta-analysis-of-randomized-trials
#2
In-Chang Hwang, Yong-Jin Kim, Jun-Bean Park, Yeonyee E Yoon, Seung-Pyo Lee, Hyung-Kwan Kim, Goo-Yeong Cho, Dae-Won Sohn
BACKGROUND: Previous studies suggested that phosphodiesterase 5 inhibitors (PDE5i) have a beneficial effect in patients with heart failure (HF), although the results were inconsistent. We performed a meta-analysis to evaluate the effect of PDE5i in HF patients, and investigated the relationship between PDE5i effects and pulmonary hemodynamics. METHOD: We searched PubMed, EMBASE and the Cochrane Library for randomized controlled trials (RCTs) that compared PDE5i with placebo in HF with reduced ejection fraction (HFrEF) or HF with preserved EF (HFpEF)...
June 12, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28566737/sex-specific-cardiopulmonary-exercise-testing-parameters-as-predictors-in-patients-with-idiopathic-pulmonary-arterial-hypertension
#3
Ping Yuan, Hui-Juan Ni, Tian-Xiang Chen, Bigyan Pudasaini, Rong Jiang, Hui Liu, Qin-Hua Zhao, Lan Wang, Su-Gang Gong, Jin-Ming Liu
Cardiopulmonary exercise testing (CPET) has been used for prognosis in idiopathic pulmonary arterial hypertension (IPAH). We explored whether sex differences had an impact on prognostic assessments of CPET in IPAH. Data were retrieved from 21 male and 36 female incident IPAH patients who underwent both right heart catheterization and CPET from 2010 to 2016 at Shanghai Pulmonary Hospital. Cox proportional hazards analysis was used to assess the prognostic value of CPET. The mean duration of follow-up was 22±15 months...
June 1, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28552098/cardiopulmonary-exercise-testing-in-aortic-stenosis
#4
Van Doan Tuyet Le
Patients with moderate to severe aortic stenosis (AVA <1.3 cm(2)) who were judged, by a referring cardiologist, as asymptomatic or equivocal symptomatic from the aortic stenosis were included in the study. Patients with left ventricular ejection fraction <50% were not included. Twenty-nine percent of the referred patients were judged asymptomatic and 71% equivocal symptomatic from their valve disease. The mean age was 72 years and 90% of the patients had an AVA-index <0.6 cm(2)/m(2). By clinical evaluation in the outpatient clinic, 48% were judged as having functional limitation corresponding to NYHA≥II...
May 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28528994/clinical-significance-of-the-overshoot-phenomena-of-respiratory-gas-indices-during-recovery-from-maximal-exercise-testing
#5
Yuta Takayanagi, Akira Koike, Osamu Nagayama, Arisa Nagamine, Rujie Qin, Jo Kato, Isao Nishi, Tomoko Himi, Yuko Kato, Akira Sato, Takeshi Yamashita, Kazutaka Aonuma
BACKGROUND: Overshoot phenomena of the gas exchange ratio (R:VCO2/VO2), ventilatory equivalent for O2 (VE/VO2), and end-tidal O2 pressure (PETO2) are commonly observed during recovery from maximal cardiopulmonary exercise testing (CPX). We investigated the clinical significance of the overshoots of these indices by comparing their magnitudes between healthy subjects and cardiac patients with left ventricular dysfunction. METHODS: In total, 121 subjects (73 healthy subjects and 48 cardiac patients with left ventricular ejection fraction<40%) who underwent CPX and achieved peak R≥1...
May 18, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28515830/how-different-respiratory-rate-patterns-affect-cardiorespiratory-variables-and-performance
#6
Minas Nalbandian, Zsolt Radak, Jun Taniguchi, Takeda Masaki
This study aims to elucidate how respiratory rate (RR) patterns may affect respiratory gas exchange variables and performance during incremental intensity- exercise. 10 healthy young men (mean ± SD, age: 20.7 ± 0.5 years, height: 174.3 ± 5.7 cm, and body mass: 72.6 ± 10.4 kg) performed three incremental tests on a cycle ergometer at three different RR (60, 45 and 30 breaths per min) in each trial. During the tests, tidal volume (TV), minute ventilation (VE), fractional content of oxygen (FeO2), fractional content of carbon dioxide (FeCO2), oxygen uptake (VO2), expiratory carbon dioxide (VCO2), equivalent of oxygen (EqO2), VE/VCO2, and respiratory exchange ratio (RER) were determinate breath-by-breath...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/28514266/pulmonary-vascular-function-and-aerobic-exercise-capacityat-moderate-altitude
#7
Vitalie Faoro, Gael Deboeck, Marco Vicenzi, Anne-Fleur Gaston, Bamodi Simaga, Grégory Doucende, Ilona Hapkova, Emma Roca, Enric Subirats, Fabienne Durand, Robert Naeije
PURPOSE: There has been suggestion that a greater "pulmonary vascular reserve" defined by a low pulmonary vascular resistance (PVR) and a high lung diffusing capacity (DL) allows for a superior aerobic exercise capacity. How pulmonary vascular reserve might affect exercise capacity at moderate altitude is not known. METHODS: Thirty-eight healthy subjects underwent an exercise stress echocardiography of the pulmonary circulation, combined with measurements of DL for nitric oxide (NO) and carbon monoxide (CO) and a cardio-pulmonary exercise test at sea level and at the altitude of 2250m...
May 17, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28487387/different-determinants-of-ventilatory-inefficiency-at-different-stages-of-reduced-ejection-fraction-chronic-heart-failure-natural-history
#8
Alessandro Mezzani, Andrea Giordano, Klara Komici, Ugo Corrà
BACKGROUND: It is not known whether determinants of ventilation (VE)/volume of exhaled carbon dioxide (VCO2) slope during incremental exercise may differ at different stages of reduced ejection fraction chronic heart failure natural history. METHODS AND RESULTS: VE/VCO2 slope was fitted up to lowest VE/VCO2 ratio, that is, a proxy of the VE/perfusion ratio devoid of nonmetabolic stimuli to ventilatory drive. VE/VCO2 slope tertiles were generated from our database (<27...
May 9, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28467885/diving-and-pulmonary-physiology-surfactant-binding-protein-lung-fluid-and-cardiopulmonary-test-changes-in-professional-divers
#9
Zora Susilovic-Grabovac, Cristina Banfi, Denise Brusoni, Massimo Mapelli, Stefania Ghilardi, Ante Obad, Darija Bakovic-Kramaric, Zeljko Dujic, Piergiuseppe Agostoni
Alteration of breathing pattern ranging from an increase of respiratory rate to overt hyperventilation during and after SCUBA diving is frequently reported and is associated with intrathoracic fluid overload. This study was undertaken to assess breathing efficiency after diving and the association with damage of alveolar cells. Ventilation efficiency (VE/VCO2) during maximal cardiopulmonary exercise test (CPET) before and 2h after a standard protocol dive has been analyzed in twelve professional males divers (39...
April 30, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28398947/acidosis-but-not-alkalosis-affects-anaerobic-metabolism-and-performance-in-a-4-km-time-trial
#10
Carlos Rafaell Correia-Oliveira, João Paulo Lopes-Silva, Romulo Bertuzzi, Glenn K McConell, David John Bishop, Adriano Eduardo Lima-Silva, Maria Augusta Peduti Dal'Molin Kiss
PURPOSE: To determine the effect of pre-exercise metabolic acidosis and alkalosis on power output (PO) and aerobic and anaerobic energy expenditure during a 4-km cycling time trial (TT). METHODS: Eleven recreationally trained cyclists (VO2peak 54.1 ± 9.3 mL·kg·min) performed a 4-km TT 100 min after ingesting in a double-blind matter 0.15 g·kg of body mass of ammonium chloride (NH4Cl, acidosis), 0.3 g·kg of sodium bicarbonate (NaHCO3, alkalosis) or 0.15 g·kg of CaCO3 (placebo)...
April 11, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28386556/effects-of-high-intensity-interval-training-on-aerobic-capacity-in-cardiac-patients-a-systematic-review-with-meta-analysis
#11
REVIEW
Bin Xie, Xianfeng Yan, Xiangna Cai, Jilin Li
Purpose. The aim of this study was to compare the effects of high-intensity interval training (INTERVAL) and moderate-intensity continuous training (CONTINUOUS) on aerobic capacity in cardiac patients. Methods. A meta-analysis identified by searching the PubMed, Cochrane Library, EMBASE, and Web of Science databases from inception through December 2016 compared the effects of INTERVAL and CONTINUOUS among cardiac patients. Results. Twenty-one studies involving 736 participants with cardiac diseases were included...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28379019/-irregular-breathing-during-the-cardiopulmonary-exercise-test-from-mildly-irregular-breathing-pattern-to-periodic-breathing-of-oscillatory-ventilation-type
#12
František Várnay, Leona Mífková, Pavel Homolka, Petr Dobšák
The fluctuating course of tidal volume (VT), breathing frequency (DF) and minute ventilation (VE) during the cardio-pulmonary exercise test using a ramp incremental protocol occurs not only in patients, but relatively frequently also in healthy individuals. It can account for a number of irregularities in the course of the curves VO2, VCO2 and in particular of those of ventilatory equivalents for O2 and CO2 (EQO2, EQCO2) as well as curves of partial pressure of end-tidal oxygen and partial pressure of end-tidal carbon dioxide (PETO2, PETCO2), which are also used, inter alia, to establish ventilatory thresholds...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28359608/changes-in-ventilatory-response-to-exercise-in-trained-athletes-respiratory-physiological-benefits-beyond-cardiovascular-performance
#13
Adriano di Paco, Bruno-Pierre Dubé, Pierantonio Laveneziana
INTRODUCTION: The beneficial impact of an 8-month competitive season on the ventilatory profile response to exercise in soccer players has never been evaluated. MATERIAL AND METHODS: Ventilatory profile (evaluated by determining individual tidal volume [VT] relative to minute ventilation [VE] inflection points during exercise) and metabolic responses to incremental exercise were evaluated in 2 professional soccer teams before and after an 8-month competitive season...
March 27, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/28337149/influence-of-inspiratory-muscle-training-on-ventilatory-efficiency-and-cycling-performance-in-normoxia-and-hypoxia
#14
Eduardo Salazar-Martínez, Hannes Gatterer, Martin Burtscher, José Naranjo Orellana, Alfredo Santalla
The aim of this study was to analyse the influence of inspiratory muscle training (IMT) on ventilatory efficiency, in normoxia and hypoxia, and to investigate the relationship between ventilatory efficiency and cycling performance. Sixteen sport students (23.05 ± 4.7 years; 175.11 ± 7.1 cm; 67.0 ± 19.4 kg; 46.4 ± 8.7 ml·kg(-1)·min(-1)) were randomly assigned to an inspiratory muscle training group (IMTG) and a control group (CG). The IMTG performed two training sessions/day [30 inspiratory breaths, 50% peak inspiratory pressure (Pimax), 5 days/week, 6-weeks]...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28334542/-an-assessment-of-vo2-kinetics-in-the-recovery-phase-of-cardiopulmonary-exercise-test-in-patients-with-heart-disease-importance-and-classification
#15
Leona Mífková, František Várnay, Pavel Homolka, Petr Dobšák
The article reviews the course of VO2 in the phase of recovery kinetics of oxygen uptake (VO2rec) cardiopulmonary exercise test. VO2rec kinetics cannot be completely defined using a single parameter. The article describes the three most frequently used methods: %VO2-REC2, T1/2 VO2rec and TC VO2, and provides detailed procedures of their analysis. The three aforementioned parameters are also at the heart of our classification of VO2rec. The method %VO2-REC2 is an essential one, in our view, since its prognostic significance is proven and it can be also easily applied only based on a data record of the cardiopulmonary exercise test...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28329277/resting-right-ventricular-function-is-associated-with-exercise-performance-in-pah-but-not-in-cteph
#16
Michaela Beatrice Rehman, Luke S Howard, Luc P Christiaens, Dipender Gill, J Simon R Gibbs, Petros Nihoyannopoulos
Aims: To assess whether resting right ventricular (RV) function assessed by Global RV longitudinal strain (RVLS) and RV fractional area change (FAC) is associated with exercise performance in pulmonary arterial hypertension (PAH) and in chronic thromboembolic pulmonary hypertension (CTEPH). Methods and results: We prospectively recruited 46 consecutive patients with PAH and 42 patients with CTEPH who were referred for cardio-pulmonary exercise testing (CPET) and transthoracic echocardiography...
February 27, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28246499/energy-systems-efficiency-influences-the-results-of-2-000-m-race-simulation-among-elite-rowers
#17
Stefan Adrian Martin, Valeriu Tomescu
HYPOTHESIS: Energy efficiency within an elite group of athletes will ensure metabolic adaptation during training. OBJECTIVES: To identify energy system efficiency and contribution according to exercise intensity, and performance obtained during a 2,000 m race simulation in an elite group of rowers. METHOD: An observational cross-sectional study was conducted in February 2016 in Bucharest, Romania, on a group of 16 elite rowers. Measurements were performed through Cosmed Quark CPET equipment, and Concept 2 ergometer, by conducting a VO2max test over a standard rowing distance of 2,000 m...
2017: Clujul Medical (1957)
https://www.readbyqxmd.com/read/28244596/cardiopulmonary-exercise-testing-improves-diagnostic-specificity-in-patients-with-echocardiography-suspected-pulmonary-hypertension
#18
Qin-Hua Zhao, Lan Wang, Bigyan Pudasaini, Rong Jiang, Ping Yuan, Su-Gang Gong, Jian Guo, Qiang Xiao, Hui Liu, Cheng Wu, Zhi-Cheng Jing, Jin-Ming Liu
BACKGROUND: Doppler echocardiography is usually the first diagnostic investigation for patients suspected with pulmonary hypertension (PH), but it is often inaccurate when used alone, especially in mild PH. HYPOTHESIS: Cardiopulmonary exercise testing (CPET) may serve as a complementary tool to improve diagnostic accuracy in echocardiography-suspected "PH possible" patients. METHODS: Eighty-eight consecutive patients with suspected PH (referred to as "PH possible" hereafter) based on echocardiography were included in the study...
February 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28238477/cardiac-rehabilitation-after-acute-coronary-syndrome-do-all-patients-derive-the-same-benefit
#19
Sílvia Aguiar Rosa, Ana Abreu, Rui Marques Soares, Pedro Rio, Custódia Filipe, Inês Rodrigues, André Monteiro, Cristina Soares, Vítor Ferreira, Sofia Silva, Sandra Alves, Rui Cruz Ferreira
INTRODUCTION: Cardiac rehabilitation (CR) has been demonstrated to improve exercise capacity in acute coronary syndrome (ACS), but not all patients derive the same benefit. Careful patient selection is crucial to maximize resources. OBJECTIVE: To identify in a heterogeneous ACS population which patients would benefit the most with CR, in terms of functional capacity (FC), by using cardiopulmonary exercise testing (CPET). METHODS: A retrospective analysis of consecutive ACS patients who underwent CR and CPET was undertaken...
March 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28237273/sex-differences-in-leptin-modulate-ventilation-in-heart-failure
#20
Ivan Cundrle, Virend K Somers, Prachi Singh, Bruce D Johnson, Christopher G Scott, Lyle J Olson
BACKGROUND: Leptin modulates ventilation and circulating levels are higher in normal women than men. OBJECTIVES: The aim of this study was to compare exercise ventilation and gas exchange in men and women with heart failure (HF) and their relation to circulating leptin concentration. METHODS: Consecutive HF patients were studied by cardiopulmonary exercise testing and assay of circulating leptin concentration. RESULTS: Fifty-seven men and 20 women were similar with respect to age, BMI, NYHA class, left ventricular ejection fraction, and peak oxygen consumption (all p > 0...
February 23, 2017: Heart & Lung: the Journal of Critical Care
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