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Sara Rosenbaum
As the principal source of health insurance for the poor, the dominant payer for long-term services and supports, the most important source of health care financing during public health crises, and the largest source of funding for the health care safety net, Medicaid occupies a central place in..
October 13, 2016: New England Journal of Medicine
Lisa Rosenbaum
In 1985, when internist Jim O’Connell, cofounder of the Boston Health Care for the Homeless Program, began doing outreach to homeless people, one of the toughest questions he faced was whether to commit someone to the hospital for involuntary psychiatric treatment. States vary in their criteria for..
October 13, 2016: New England Journal of Medicine
Sara L Morales-Lázaro, Itzel Llorente, Félix Sierra-Ramírez, Ana E López-Romero, Miguel Ortíz-Rentería, Barbara Serrano-Flores, Sidney A Simon, León D Islas, Tamara Rosenbaum
The transient receptor potential vanilloid 1 (TRPV1) ion channel is mainly found in primary nociceptive afferents whose activity has been linked to pathophysiological conditions including pain, itch and inflammation. Consequently, it is important to identify naturally occurring antagonists of this channel. Here we show that a naturally occurring monounsaturated fatty acid, oleic acid, inhibits TRPV1 activity, and also pain and itch responses in mice by interacting with the vanilloid (capsaicin)-binding pocket and promoting the stabilization of a closed state conformation...
October 10, 2016: Nature Communications
Davy Vancampfort, Michel Probst, Sabine Wyckaert, Marc De Hert, Brendon Stubbs, Simon Rosenbaum, Pascal Sienaert
The most significant contributor to premature mortality in patients with bipolar disorder is preventable cardiovascular diseases. This study investigated if the Physical Activity Vital Sign (PAVS) assessment (two questions which clarify if a person meets the recommended 150min of physical activity per week) can identify patients with bipolar disorder at higher risk of cardio-metabolic abnormalities. Clinical differences between those who adhere and those who did not adhere to the physical activity guidelines were investigated using an ANCOVA controlling for age and gender...
October 5, 2016: Psychiatry Research
Davy Vancampfort, James Mugisha, Simon Rosenbaum, Joseph Firth, Marc De Hert, Michel Probst, Brendon Stubbs
Cardiorespiratory fitness (CRF) is a modifiable risk factor for cardiovascular disease and premature mortality. CRF levels and moderators among people living with HIV (PLWH) are unknown. The aim of the current meta-analysis was to (1) determine mean CRF in PLWH and compare levels with age- and gender-matched healthy controls (HCs), (2) explore moderators of CRF, (3) and (4) explore moderators of CRF outcomes following physical activity (PA) interventions. Major electronic databases were searched systematically for articles reporting CRF expressed as maximum or peak oxygen uptake (ml/min/kg) in PLWH...
October 3, 2016: Preventive Medicine
J M Rosenbaum, B R Coolman, B L Davidson, M L Daly, J F Rexing, A E Eatroff
OBJECTIVE: To describe the use of disposable skin staples for intestinal resection and anastomosis in dogs and report associated dehiscence and mortality rates. METHODS: Retrospective evaluation of medical records of dogs that underwent intestinal resection and anastomosis using disposable skin staples between 2000 and 2014. Data regarding patient signalment, indication for surgery, location of the resection and anastomosis, number of procedures performed, evidence of peritonitis at the time of surgery, surgeon qualifications, dehiscence, and mortality were obtained from the medical records...
October 5, 2016: Journal of Small Animal Practice
Yishu Wang, Yejun Feng, J-G Cheng, W Wu, J L Luo, T F Rosenbaum
Magnetic and superconducting ground states can compete, cooperate and coexist. MnP provides a compelling and potentially generalizable example of a material where superconductivity and magnetism may be intertwined. Using a synchrotron-based non-resonant X-ray magnetic diffraction technique, we reveal a spiral spin order in MnP and trace its pressure evolution towards superconducting order via measurements in a diamond anvil cell. Judging from the magnetostriction, ordered moments vanish at the quantum phase transition as pressure increases the electron kinetic energy...
October 6, 2016: Nature Communications
Nina Reinholt, Ruth Aharoni, Clas Winding, Nicole Rosenberg, Bent Rosenbaum, Sidse Arnfred
Comorbidity among the anxiety disorders is common and may negatively impact treatment outcome. Potentially, transdiagnostic cognitive-behavioral treatments (CBT) deal more effectively with comorbidity than standard CBT. The present study tested the effectiveness of The Unified Protocol (UP) applied to Mental Health Services. Pre-post-treatment effects were examined for psychiatric outpatients with anxiety disorders receiving UP treatment in groups. Forty-seven patients (mean-age = 34.1 (SD = 9.92), 77% females) with a principal diagnosis of anxiety were included...
October 5, 2016: Cognitive Behaviour Therapy
B Stubbs, A Koyanagi, F B Schuch, J Firth, S Rosenbaum, N Veronese, M Solmi, J Mugisha, D Vancampfort
OBJECTIVE: Physical activity (PA) is good for health, yet several small-scale studies have suggested that depression is associated with low PA. A paucity of nationally representative studies investigating this relationship exists, particularly in low- and middle-income countries (LMICs). This study explored the global association of PA with depression and its mediating factors. METHOD: Participants from 36 LMICs from the World Health Survey were included. Multivariable logistic regression analyses were undertaken exploring the relationship between PA and depression...
October 5, 2016: Acta Psychiatrica Scandinavica
Paul R Rosenbaum, Dylan S Small
In a sensitivity analysis in an observational study with a binary outcome, is it better to use all of the data or to focus on subgroups that are expected to experience the largest treatment effects? The answer depends on features of the data that may be difficult to anticipate, a trade-off between unknown effect-sizes and known sample sizes. We propose a sensitivity analysis for an adaptive test similar to the Mantel-Haenszel test. The adaptive test performs two highly correlated analyses, one focused analysis using a subgroup, one combined analysis using all of the data, correcting for multiple testing using the joint distribution of the two test statistics...
October 4, 2016: Biometrics
Andrew J Rosenbaum, Andrew Dunkman, Daniel Goldberg, Richard L Uhl, Michael Mulligan
Background: Approximately 33% of Americans have inadequate health literacy, which is associated with infrequent use of preventative services, increased hospitalization and use of emergency care, and worse control of chronic diseases. In this study, the Literacy in Musculoskeletal Problems (LiMP) questionnaire was used to evaluate the prevalence of limited musculoskeletal literacy in patients undergoing carpal tunnel release (CTR), as these individuals may be at increased risk of inferior outcomes. Methods: This cross-sectional study included individuals older than or equal to 18 years of age who were scheduled for elective CTR...
September 2016: Hand: Official Journal of the American Association for Hand Surgery
Sergey Motov, Steven Rosenbaum, Gary M Vilke, Yuko Nakajima
BACKGROUND: Whether acute or chronic, emergency physicians frequently encounter patients reporting pain. It is the responsibility of the emergency physician to assess and evaluate, and if appropriate, safely and effectively reduce pain. Recently, analgesics other than opioids are being considered in an effort to provide safe alternatives for pain management in the emergency department (ED). Opioids have significant adverse effects such as respiratory depression, hypotension, and sedation, to say nothing of their potential for abuse...
September 29, 2016: Journal of Emergency Medicine
Daniel G Rosenbaum, Maire A Conrad, David M Biko, Eduardo D Ruchelli, Judith R Kelsen, Sudha A Anupindi
BACKGROUND: Imaging predictors for surgery in children with Crohn disease are lacking. OBJECTIVE: To identify imaging features of the terminal ileum on short-interval bowel ultrasound (US) and MR enterography (MRE) in children with Crohn disease requiring surgical bowel resection and those managed by medical therapy alone. MATERIALS AND METHODS: This retrospective study evaluated patients 18 years and younger with Crohn disease undergoing short-interval bowel US and MRE (within 2 months of one another), as well as subsequent ileocecectomy or endoscopy within 3 months of imaging...
September 29, 2016: Pediatric Radiology
Elena Antonov, Steffen Wirth, Tim Gerlach, Ivan Schlembach, Miriam A Rosenbaum, Lars Regestein, Jochen Büchs
BACKGROUND: Pretreated lignocellulosic biomass is considered as a suitable feedstock for the sustainable production of chemicals. However, the recalcitrant nature of cellulose often results in very cost-intensive overall production processes. A promising concept to reduce the costs is consolidated bioprocessing, which integrates in a single step cellulase production, cellulose hydrolysis, and fermentative conversion of produced sugars into a valuable product. This approach, however, requires assessing the digestibility of the applied celluloses and, thus, the released sugar amount during the fermentation...
September 29, 2016: Microbial Cell Factories
Joan Rosenbaum Asarnow, Peter Wang
No abstract text is available yet for this article.
September 28, 2016: Evidence-based Mental Health
Nancy Rosenbaum Hofmann
No abstract text is available yet for this article.
September 28, 2016: Plant Cell
J Rosenbaum, C Kuhn, F F Tu, K M Hellman
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
Sophie Béliard, Aurélie Millier, Valérie Carreau, Alain Carrié, Philippe Moulin, Alexandre Fredenrich, Michel Farnier, Gérald Luc, David Rosenbaum, Mondher Toumi, Eric Bruckert
BACKGROUND: Heterozygous familial hypercholesterolemia (heFH) is a genetic disease causing high levels of low-density lipoprotein cholesterol (LDL-C). Although this population is at high cardiovascular (CV) risk, the risk is variable within patients depending on additional risk factors. CV disease risk groups have been defined by the Nouvelle Société Francophone d'Athérosclérose (NSFA) and by the National Lipid Association recommendations. OBJECTIVES: The study aimed to describe a sample of French heFH patients, comparing patients at very high risk (VHR) and patients at high risk in terms of demographic and clinical characteristics as well as biological measurements and disease management...
September 2016: Journal of Clinical Lipidology
Pierre Marois, Mikael Marois, Annie Pouliot-Laforte, Michel Vanasse, Jean Lambert, Laurent Ballaz
OBJECTIVE: To develop a new way to interpret Gross Motor Function Measure (GMFM-66) score improvement in studies conducted without control groups in children with cerebral palsy (CP). MATERIAL AND METHODS: The curves, which describe the pattern of motor development according to the children's Gross Motor Function Classification System level, were used as historical control to define the GMFM-66 expected natural evolution in children with CP. These curves have been modeled and generalized to fit the curve to particular children characteristics...
September 2016: Annals of Physical and Rehabilitation Medicine
Stevenson Baker, Paula Vieweg, Fuqiang Gao, Asaf Gilboa, Thomas Wolbers, Sandra E Black, R Shayna Rosenbaum
Our day-to-day experiences are often similar to one another, occurring in the same place at the same time of day, with common people and objects, and with a shared purpose. Humans have an episodic memory to represent unique, personal events that are rich in detail [1]. For this to occur, at least two basic neural mechanisms are required: one to orthogonalize or "separate" overlapping input patterns at encoding and another to reinstate or "complete" memories from partial cues at retrieval [2-6]. To what extent do these purported "pattern separation" and "pattern completion" mechanisms rely on distinct subfields of the hippocampus [6]? Computational models [4-6] and lesion and genetic studies in rodents [7-12] largely point to the dentate gyrus as responsible for pattern separation and the CA3 and CA1 subfields for pattern completion (but see [13-16])...
October 10, 2016: Current Biology: CB
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