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https://www.readbyqxmd.com/read/28526867/aberrant-functional-connectivity-in-depression-as-an-index-of-state-and-trait-rumination
#1
David Rosenbaum, Alina Haipt, Kristina Fuhr, Florian B Haeussinger, Florian G Metzger, Hans-Christoph Nuerk, Andreas J Fallgatter, Anil Batra, Ann-Christine Ehlis
Depression has been shown to be related to a variety of aberrant brain functions and structures. Particularly the investigation of alterations in functional connectivity (FC) in major depressive disorder (MDD) has been a promising endeavor, since a better understanding of pathological brain networks may foster our understanding of the disease. However, the underling mechanisms of aberrant FC in MDD are largely unclear. Using functional near-infrared spectroscopy (fNIRS) we investigated FC in the cortical parts of the default mode network (DMN) during resting-state in patients with current MDD...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28524643/racial-and-ethnic-minority-enrollment-in-randomized-clinical-trials-of-behavioural-weight-loss-utilizing-technology-a-systematic-review
#2
REVIEW
D L Rosenbaum, A D Piers, L M Schumacher, C A Kase, M L Butryn
Many racial and ethnic minority groups (minorities) are disproportionately affected by overweight and obesity; however, minorities are often under-represented in clinical trials of behavioural weight loss (BWL) treatment, potentially limiting the generalizability of these trials' conclusions. Interventions involving technology may be particularly well suited to overcoming the barriers to minority enrollment in BWL trials, such as demanding or unpredictable work schedules, caregiving responsibilities and travel burdens...
May 19, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28521838/does-the-use-of-the-informed-healthcare-choices-ihc-primary-school-resources-improve-the-ability-of-grade-5-children-in-uganda-to-assess-the-trustworthiness-of-claims-about-the-effects-of-treatments-protocol-for-a-cluster-randomised-trial
#3
Allen Nsangi, Daniel Semakula, Andrew D Oxman, Matthew Oxman, Sarah Rosenbaum, Astrid Austvoll-Dahlgren, Laetitia Nyirazinyoye, Margaret Kaseje, Iain Chalmers, Atle Fretheim, Nelson K Sewankambo
BACKGROUND: The ability to appraise claims about the benefits and harms of treatments is crucial for informed health care decision-making. This research aims to enable children in East African primary schools (the clusters) to acquire and retain skills that can help them make informed health care choices by improving their ability to obtain, process and understand health information. The trial will evaluate (at the individual participant level) whether specially designed learning resources can teach children some of the key concepts relevant to appraising claims about the benefits and harms of health care interventions (treatments)...
May 18, 2017: Trials
https://www.readbyqxmd.com/read/28520636/commentary-on-counterbalanced-comparison-of-the-bayley-scales-of-infant-development-ii-and-iii-at-18-to-22-months-corrected-age
#4
Peter Rosenbaum
No abstract text is available yet for this article.
May 16, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28520541/outcomes-and-prognostic-factors-for-adult-patients-with-congenital-heart-disease-undergoing-primary-or-reoperative-systemic-atrioventricular-valve-surgery
#5
Elizabeth H Stephens, Jiho Han, Jonathan Ginns, Marlon Rosenbaum, Paul Chai, Emile Bacha, David Kalfa
BACKGROUND: Adults with congenital heart disease (ACHD) undergoing systemic atrioventricular valve (SAVV) surgery are a complex, understudied population. We assessed midterm outcomes and prognostic factors in ACHD undergoing SAVV surgery. METHODS: We performed retrospective evaluation of ACHD undergoing SAVV surgery from January 2005 to February 2016: 14 (33%) patients with congenital mitral valve stenosis/regurgitation, 15 (35%) with atrioventricular septal defect (AVSD), and 14 (33%) with congenitally corrected transposition of the great arteries (ccTGA) with systemic tricuspid valve regurgitation...
May 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28515181/measuring-ability-to-assess-claims-about-treatment-effects-the-development-of-the-claim-evaluation-tools
#6
Astrid Austvoll-Dahlgren, Daniel Semakula, Allen Nsangi, Andrew David Oxman, Iain Chalmers, Sarah Rosenbaum, Øystein Guttersrud
OBJECTIVES: To describe the development of the Claim Evaluation Tools, a set of flexible items to measure people's ability to assess claims about treatment effects. SETTING: Methodologists and members of the community (including children) in Uganda, Rwanda, Kenya, Norway, the UK and Australia. PARTICIPANTS: In the iterative development of the items, we used purposeful sampling of people with training in research methodology, such as teachers of evidence-based medicine, as well as patients and members of the public from low-income and high-income countries...
May 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28514226/the-march-of-science-the-true-story
#7
Lisa Rosenbaum
"The human understanding when it has once adopted an opinion...draws all things else to support and agree with it." Francis Bacon, the "Father of Empiricism," came to this conclusion in the 17th century, and some 350 years later, three Stanford psychologists confirmed its validity. They recruited..
May 17, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28504637/-evidence-of-the-effect-of-psychodynamic-psychotherapy
#8
Francisco Alberdi Olano, Bent Rosenbaum
Evidence of the effect of psychodynamic psychotherapy (PDT) has been called into question. Thus, an updated review of the effect of short-term and long-term PDT (STPP and LTPP) for anxiety, depression and personality disorders seems necessary. A systematic search of randomized controlled studies of PDT published from January 2000 to May 2016 was conducted, and we found 57 single studies and 13 meta-analyses fulfilling the criteria for inclusion. The studies show that PDT has therapeutic efficacy and effectiveness matching other forms of psychotherapy...
May 15, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28494227/spontaneous-quorum-sensing-mutation-modulates-electroactivity-of-pseudomonas-aeruginosa-pa14
#9
Carola Berger, Miriam A Rosenbaum
Pseudomonas aeruginosa is able to interact with the anode of a bioelectrochemical system through redox active phenazines. Earlier studies showed that this interaction is strain and carbon source dependent. With a spontaneously formed ΔlasR mutant of P. aeruginosa PA14 and the wildtype, we investigated the connection between the complex quorum sensing network and current production. Depending on the carbon source, phenazine production and subsequently current generation are effected differently in these two populations...
April 29, 2017: Bioelectrochemistry
https://www.readbyqxmd.com/read/28485850/child-and-parent-reported-quality-of-life-trajectories-in-children-with-epilepsy-a-prospective-cohort-study
#10
Mark A Ferro, Lisa Avery, Nora Fayed, David L Streiner, Charles E Cunningham, Michael H Boyle, Lucyna Lach, Gina Glidden, Peter L Rosenbaum, Gabriel M Ronen
OBJECTIVE: To describe the developmental trajectories of quality of life (QoL) in a large cohort of children with epilepsy, and to assess the relative contribution of clinical, psychosocial, and sociodemographic variables on QoL trajectories. METHODS: Five assessments during a 28-month prospective cohort study were used to model trajectories of QoL. Participants were recruited with their parents from six Canadian tertiary centers. A convenience sample of 506 children aged 8-14 years with epilepsy and without intellectual disability or autism spectrum disorder were enrolled...
May 9, 2017: Epilepsia
https://www.readbyqxmd.com/read/28479479/direct-vision-internal-urethrotomy-for-short-anterior-urethral-strictures-and-beyond-success-rates-predictors-of-treatment-failure-and-recurrence-management
#11
Luis A Kluth, Lukas Ernst, Malte W Vetterlein, Christian P Meyer, C Philip Reiss, Margit Fisch, Clemens M Rosenbaum
OBJECTIVES: To determine success rates, predictors of recurrence and recurrence management of patients treated for short anterior urethral strictures by direct vision internal urethrotomy (DVIU). METHODS: We identified 128 patients who underwent DVIU of the anterior urethra between December 2009 and March 2016. Follow-up was conducted by telephone interviews. Success rates were assessed by Kaplan-Meier estimators. Predictors of stricture recurrence and different further therapy strategies were identified by uni- and multivariable Cox regression analyses...
May 4, 2017: Urology
https://www.readbyqxmd.com/read/28468683/policymaker-experiences-with-rapid-response-briefs-to-address-health-system-and-technology-questions-in-uganda
#12
Rhona Mijumbi-Deve, Sarah E Rosenbaum, Andrew D Oxman, John N Lavis, Nelson K Sewankambo
BACKGROUND: Health service and systems researchers have developed knowledge translation strategies to facilitate the use of reliable evidence for policy, including rapid response briefs as timely and responsive tools supporting decision making. However, little is known about users' experience with these newer formats for presenting evidence. We sought to explore Ugandan policymakers' experience with rapid response briefs in order to develop a format acceptable for policymakers. METHODS: We used existing research regarding evidence formats for policymakers to inform the initial version of rapid response brief format...
May 3, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28463457/cerebral-palsy-is-the-concept-still-viable
#13
EDITORIAL
Peter Rosenbaum
No abstract text is available yet for this article.
June 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28456681/early-coronary-calcifications-are-related-to-cholesterol-burden-in-heterozygous-familial-hypercholesterolemia
#14
Antonio Gallo, Philippe Giral, Alain Carrié, Valérie Carreau, Sophie Béliard, Randa Bittar, Marianna Maranghi, Marcello Arca, Philippe Cluzel, Alban Redheuil, Eric Bruckert, David Rosenbaum
BACKGROUND: The identification of high-risk patients with heterozygous familial hypercholesterolemia (HeFH) that may benefit from early treatment is challenging. Coronary Artery Calcification (CAC) score accounts for coronary atherosclerotic burden. It has proven its accuracy in cardiovascular risk assessment in the general population but data in HeFH are lacking. OBJECTIVE: The aim of our study was to assess CAC prevalence and its relationship with lifelong cholesterol exposure, calculated by total cholesterol burden (TCB) in patients with HeFH...
April 4, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28456072/can-smartphone-mental-health-interventions-reduce-symptoms-of-anxiety-a-meta-analysis-of-randomized-controlled-trials
#15
REVIEW
Joseph Firth, John Torous, Jennifer Nicholas, Rebekah Carney, Simon Rosenbaum, Jerome Sarris
BACKGROUND: Various psychological interventions are effective for reducing symptoms of anxiety when used alone, or as an adjunct to anti-anxiety medications. Recent studies have further indicated that smartphone-supported psychological interventions may also reduce anxiety, although the role of mobile devices in the treatment and management of anxiety disorders has yet to be established. METHODS: We conducted a systematic review and meta-analysis of all randomized clinical trials (RCTs) reporting the effects of psychological interventions delivered via smartphone on symptoms of anxiety (sub-clinical or diagnosed anxiety disorders)...
April 25, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28451514/dysphagia-rates-after-anterior-cervical-diskectomy-and-fusion-a-systematic-review-and-meta-analysis
#16
REVIEW
Michael F Shriver, Daniel J Lewis, Varun R Kshettry, Benjamin P Rosenbaum, Edward C Benzel, Thomas E Mroz
STUDY DESIGN:  Systematic review and meta-analysis. OBJECTIVE: Anterior cervical diskectomy and fusion (ACDF) is an effective surgical option for patients with cervical radiculopathy, myelopathy, or deformity. Although ACDF is generally safe, dysphagia is a common complication. Despite its high incidence, prolonged postoperative dysphagia is poorly understood; its etiology remains relatively unknown, and its risk factors are widely debated. METHODS: We searched MEDLINE, Scopus, Web of Science, and Embase for studies reporting complications for cervical diskectomy with plating...
February 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28450887/process-relevant-screening-of-cellulolytic-organisms-for-consolidated-bioprocessing
#17
Elena Antonov, Ivan Schlembach, Lars Regestein, Miriam A Rosenbaum, Jochen Büchs
BACKGROUND: Although the biocatalytic conversion of cellulosic biomass could replace fossil oil for the production of various compounds, it is often not economically viable due to the high costs of cellulolytic enzymes. One possibility to reduce costs is consolidated bioprocessing (CBP), integrating cellulase production, hydrolysis of cellulose, and the fermentation of the released sugars to the desired product into one process step. To establish such a process, the most suitable cellulase-producing organism has to be identified...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28445080/bridging-the-data-sharing-divide-seeing-the-devil-in-the-details-not-the-other-camp
#18
Lisa Rosenbaum
No abstract text is available yet for this article.
April 26, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28443675/the-effect-of-trigger-finger-injection-site-on-injection-related-pain
#19
Yoseph A Rosenbaum, Nikki Benvenuti, Jingzhen Yang, Michael E Ruff, Hisham M Awan, Julie Balch Samora
BACKGROUND: Stenosing tenosynovitis, or trigger digit, is a common condition for which patients often seek relief. Corticosteroid injections have been shown to provide relief in many cases, and several different approaches for delivering the injection have been described in the literature. We compared patients' perception of pain following each of 3 accepted injection methods, namely, palmar proximal, palmar distal, and webspace approaches. METHODS: We prospectively followed 38 patients with 39 symptomatic digits in this trial, with varying severities of trigger finger as graded by the Patel and Moradia classification...
April 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28437038/impact-of-preoperative-risk-on-metastatic-progression-and-cancer-specific-death-in-patients-with-adverse-pathology-at-radical-prostatectomy
#20
Katharina Boehm, Sami-Ramzi Leyh-Bannurah, Clemens Rosenbaum, Laurenz S Brandi, Lars Budäus, Markus Graefen, Hartwig Huland, Axel Haferkamp, Derya Tilki
OBJECTIVE: To evaluate the impact of preoperative risk category on metastatic disease (MetD) and prostate cancer mortality (CSM) in prostate cancer (PCa) patients with adverse pathology at radical prostatectomy (RP). PATIENTS AND METHODS: The records of 6943 patients who underwent radical prostatectomy (RP) in a European tertiary-center were analysed. Biochemical recurrence (BCR), MetD and CSM were assessed for patients with adverse pathology at RP and stratified according to preoperative low- vs...
April 24, 2017: BJU International
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