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https://www.readbyqxmd.com/read/29778262/understanding-and-addressing-hepatitis-c-virus-reinfection-among-men-who-have-sex-with-men
#1
REVIEW
Thomas C S Martin, Andri Rauch, Luisa Salazar-Vizcaya, Natasha K Martin
Hepatitis C virus reinfection rates among men who have sex with men are high. Factors associated with infection point to varied sexual and drug-related risks that could be targeted for interventions to prevent infection/reinfection. Modeling indicates that tackling increasing incidence and high reinfection rates requires high levels of hepatitis C virus treatment combined with behavioral interventions. Enhanced testing strategies and prompt retreating of reinfection may be required to promptly diagnosed reinfections...
June 2018: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/29778261/strategies-to-reduce-hepatitis-c-virus-reinfection-in-people-who-inject-drugs
#2
REVIEW
Marianne Martinello, Gregory J Dore, Gail V Matthews, Jason Grebely
Reinfection after direct-acting antiviral therapy may pose a challenge to hepatitis C virus elimination efforts. Reinfection risk is cited as a reason for not offering treatment to people who inject drugs. As treatment scale-up expands among populations with risks for reacquisition, acknowledgment that reinfection can and will occur is essential. Efforts to prevent and manage reinfection should be incorporated into individual- and population-level strategies. The risk of reinfection after successful treatment emphasises the need for education, harm reduction, and posttreatment surveillance...
June 2018: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/29776688/naloxone-laws-facilitate-the-establishment-of-overdose-education-and-naloxone-distribution-programs-in-the-united-states
#3
Barrot H Lambdin, Corey S Davis, Eliza Wheeler, Stephen Tueller, Alex H Kral
BACKGROUND: The opioid overdose crisis in the United States continues to worsen. Opioid overdose mortality is entirely preventable with timely administration of naloxone. Since 2001, many states have passed laws to create an enabling environment for the implementation of overdose education and naloxone distribution (OEND) programs. We assessed whether state-level naloxone laws and their provisions stimulated the implementation of OEND programs in the United States. METHODS: Covering the period from 2000 to 2014, we utilized five data sources including the Westlaw legal database, the Prescription Drug Abuse Policy System, the Harm Reduction Coalition's OEND database, National Center of Health Statistics and the United States Census...
May 12, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29776368/comparing-risk-environments-for-hiv-among-people-who-inject-drugs-from-three-cities-in-northern-mexico
#4
Angelica Ospina-Escobar, Carlos Magis-Rodríguez, Fatima Juárez, Dan Werb, Sergio Bautista Arredondo, Rubén Carreón, María Elena Ramos, Steffanie Strathdee
BACKGROUND: A large body of research has investigated the rise of injection drug use and HIV transmission in Tijuana and Ciudad Juarez (CJ). However, little is known about the dynamics of injecting in Hermosillo. This study compares drug-related behaviors and risk environment for HIV of people who inject drugs (PWID) across Tijuana, CJ, and Hermosillo to identify factors that could explain differences in HIV prevalence. METHODS: Data from Tijuana belong to a prospective study (El Cuete IV)...
May 18, 2018: Harm Reduction Journal
https://www.readbyqxmd.com/read/29775956/typology-of-new-psychoactive-substance-use-among-the-general-australian-population
#5
Rachel Sutherland, Amy Peacock, Amanda Roxburgh, Monica J Barratt, Lucinda Burns, Raimondo Bruno
AIM: The aim of this study was to examine the typology of Australian illicit drug consumers to determine whether those who use new psychoactive substances (NPS) differ from those using other illicit substances. METHODS: Data were from the 2013 National Drug Strategy Household Survey, a representative population study; analyses were limited to participants reporting past year illicit drug use (including NPS; n = 3309). Latent class analysis identified groups based on past year substance use, and a weighted multivariable, multinomial regression model was used to examine characteristics associated with group membership...
May 3, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29774442/integrated-models-of-care-for-individuals-with-opioid-use-disorder-how-do-we-prevent-hiv-and-hcv
#6
REVIEW
Katherine M Rich, Joshua Bia, Frederick L Altice, Judith Feinberg
PURPOSE OF REVIEW: To describe models of integrated and co-located care for opioid use disorder (OUD), hepatitis C (HCV), and HIV. RECENT FINDINGS: The design and scale-up of multidisciplinary care models that engage, retain, and treat individuals with HIV, HCV, and OUD are critical to preventing continued spread of HIV and HCV. We identified 17 models within primary care (N = 3), HIV specialty care (N = 5), opioid treatment programs (N = 6), transitional clinics (N = 2), and community-based harm reduction programs (N = 1), as well as two emerging models...
May 17, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29772688/modeling-the-population-health-impact-of-introducing-a-modified-risk-tobacco-product-into-the-u-s-market
#7
Smilja Djurdjevic, Peter N Lee, Rolf Weitkunat, Zheng Sponsiello-Wang, Frank Lüdicke, Gizelle Baker
Philip Morris International (PMI) has developed the Population Health Impact Model (PHIM) to quantify, in the absence of epidemiological data, the effects of marketing a candidate modified risk tobacco product (cMRTP) on the public health of a whole population. Various simulations were performed to understand the harm reduction impact on the U.S. population over a 20-year period under various scenarios. The overall reduction in smoking attributable deaths (SAD) over the 20-year period was estimated as 934,947 if smoking completely went away and between 516,944 and 780,433 if cMRTP use completely replaces smoking...
May 16, 2018: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29770101/resources-to-address-stigma-related-to-sexuality-substance-use-and-sexually-transmitted-and-blood-borne-infections
#8
R MacLean
Background: Stigma is widely recognized as a significant barrier to the prevention, management and treatment of sexually transmitted and blood-borne infections (STBBIs) in Canada. Despite major advances in STBBI prevention and treatment, and global efforts to reduce stigma, people living with or affected by STBBIs continue to experience stigma within health and social service settings in Canada. Objective: To describe the development, content and evaluation of knowledge translation resources and training workshops designed to equip health and social service professionals with the knowledge and skills needed to provide more respectful and inclusive sexual health, harm reduction and STBBI services...
February 1, 2018: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29761160/measuring-and-preventing-alcohol-use-and-related-harm-among-young-people-in-asian-countries-a-thematic-review
#9
REVIEW
Heng Jiang, Xiaojun Xiang, Wei Hao, Robin Room, Xiaojie Zhang, Xuyi Wang
Background: The paper reviews alcohol consumption patterns and alcohol-related social and health issues among 15-29-year old young people in Asian countries, and discusses strategies for preventing and controlling alcohol use and related harms. Methods: We searched Google Scholar, PubMed, and Web of Science for reports, reviews and journal articles published in English between 1st Jan 1990 and 31st August 2016. Results: Forty-one reports, reviews and journal papers were identified and included in the final review...
2018: Global Health Research and Policy
https://www.readbyqxmd.com/read/29754895/drug-consumption-rooms-comparing-times-spaces-and-actors-in-issues-of-social-acceptability-in-french-public-debate
#10
Marie Jauffret-Roustide, Isabelle Cailbault
BACKGROUND: In October 2016, the first French drug consumption room (DCR) opened in Paris. We propose to examine the process through which this issue has been framed as a matter of public concern, after being ignored for almost 20 years. Our analysis of the controversy on DCRs investigates how public conversations on harm reduction evolve according to the time period (from the 1990s to the present), scale of discourse (local vs. national), and involved actors (politicians, professionals, local residents, and drug users)...
May 10, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29754597/re-wired-treatment-and-peer-support-for-men-who-have-sex-with-men-who-use-methamphetamine
#11
Kent Burgess, Garth Parkhill, Jeremy Wiggins, Simon Ruth, Mark Stoovè
Background This paper examines a methamphetamine treatment and peer support program for gay men and other men who have sex with men (MSM) who use methamphetamine. Australian MSM use illicit drugs including methamphetamine at significantly higher rates than the broader community.1,2 Methamphetamine rates are higher again amongst HIV positive MSM. Methamphetamine in the MSM community is associated with sexual activity and may be associated with psychosocial harms including risk of the transmission of HIV and sexually transmissible infections...
April 2018: Sexual Health
https://www.readbyqxmd.com/read/29754104/measuring-individual-level-needle-and-syringe-coverage-among-people-who-inject-drugs-in-myanmar
#12
Daniel O'Keefe, Soe Moe Aung, Naanki Pasricha, Thu Wun, Soe Khaing Linn, Nay Lin, Campbell Aitken, Chad Hughes, Paul Dietze
BACKGROUND: Myanmar has prioritised people who inject drugs (PWID) as a key population for HIV mitigation efforts, with targets for needle and syringe distribution set at a population level. However, individual-level coverage, defined as the percentage of an individual's injecting episodes covered by a sterile syringe, is a more sensitive measure of intervention coverage. We sought to examine individual-level coverage in a sample of PWID in Myanmar. METHODS: We recruited 512 PWID through urban drop-in-centres in Yangon, Mandalay and Pyin Oo Lwin...
May 10, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29752698/opioid-use-among-those-who-have-criminal-justice-experience-harm-reduction-strategies-to-lessen-hiv-risk
#13
REVIEW
Lauren Brinkley-Rubinstein, David Cloud, Ernest Drucker, Nickolas Zaller
PURPOSE OF REVIEW: We reviewed the HIV and opioid literature relevant to harm reduction strategies for those with criminal justice experience. RECENT FINDINGS: Opioid use in the United States has risen at an alarming rate recently. This has led to increased numbers of people who inject drugs, placing new populations at risk for HIV, including those who have criminal justice experience. In recent years, there has been a gradual decrease in the number of individuals under the supervision of the criminal justice system...
May 11, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29751889/gender-and-geographical-inequalities-in-fatal-drug-overdose-in-iran-a-province-level-study-in-2006-and-2011
#14
Mehran Rostami, Mohammad Karamouzian, Ardeshir Khosravi, Shahab Rezaeian
AIM: We aimed to compare the fatal drug overdose rates in Iran in 2006 and 2011. METHODS: This analysis was performed based on data on fatal drug overdose cases from the Iranian death registration system. The crude and adjusted rates per 100,000 populations for geographical regions stratified by gender and age groups were calculated using the 2006 and 2011 census of Iranian population. Annual percentage change was calculated to examine annual changes of fatal drug overdose rates across different regions...
June 2018: Spatial and Spatio-temporal Epidemiology
https://www.readbyqxmd.com/read/29751763/harm-reduction-and-viral-hepatitis-c-in-european-prisons-a-cross-sectional-survey-of-25-countries
#15
Rob Bielen, Samya R Stumo, Rachel Halford, Klára Werling, Tatjana Reic, Heino Stöver, Geert Robaeys, Jeffrey V Lazarus
BACKGROUND: Current estimates suggest that 15% of all prisoners worldwide are chronically infected with the hepatitis C virus (HCV), and this number is even higher in regions with high rates of injecting drug use. Although harm reduction services such as opioid substitution therapy (OST) and needle and syringe programs (NSPs) are effective in preventing the further spread of HCV and HIV, the extent to which these are available in prisons varies significantly across countries. METHODS: The Hep-CORE study surveyed liver patient groups from 25 European countries in 2016 and mid-2017 on national policies related to harm reduction, testing/screening, and treatment for HCV in prison settings...
May 11, 2018: Harm Reduction Journal
https://www.readbyqxmd.com/read/29748063/-is-reduction-of-tobacco-consumption-associated-with-reduced-risk-of-cardiovascular-and-pulmonary-mortality-and-morbidity
#16
REVIEW
M Underner, G Peiffer, J Perriot, G Harika-Germaneau, N Jaafari
INTRODUCTION: Smokers without an intention to completely quit smoking often try to reduce their daily tobacco consumption. However, smoking reduction is not associated with reduced risk of all-cause mortality. The aim of this systematic literature review of data was to expose relations between reduction of daily tobacco consumption and a potential decrease in the risks of cardiovascular and pulmonary mortality and morbidity. METHOD: Medline, on the period 1980-2018 with the following keywords: "smoking reduction", "harm reduction", "mortality", "morbidity", "cardiovascular disease* ", myocardial infarction", "coronar* ", "stroke", "lung cancer", "COPD", "chronic obstructive pulmonary disease", "asthma", "pulmonary disease* " and "respiratory disease" limits "title/abstract"; the selected languages were English or French...
May 7, 2018: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/29740734/syringe-decriminalization-advocacy-in-red-states-lessons-from-the-north-carolina-harm-reduction-coalition
#17
REVIEW
David H Cloud, Tessie Castillo, Lauren Brinkley-Rubinstein, Manisha Dubey, Robert Childs
PURPOSE OF REVIEW: Syringe access programs (SAPs) are cornerstone harm reduction interventions for combatting the national opioid epidemic. The goal of this paper is to describe effective advocacy strategies for enacting syringe decriminalization legislation to foster the expansion of SAPs in high-need areas amidst political opposition. RECENT FINDINGS: Decades or research shows that SAPs prevent the transmission of HIV among people who inject drugs (PWID) and are a cost-effective tool for linking PWID to medical care, health education, and social services...
May 8, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29740356/behavioural-pharmacokinetic-metabolic-and-hyperthermic-profile-of-3-4-methylenedioxypyrovalerone-mdpv-in-the-wistar-rat
#18
Rachel R Horsley, Eva Lhotkova, Katerina Hajkova, Barbara Feriancikova, Michal Himl, Martin Kuchar, Tomas Páleníček
3,4-methylenedioxypyrovalerone (MDPV) is a potent pyrovalerone cathinone that is substituted for amphetamines by recreational users. We report a comprehensive and detailed description of the effects of subcutaneous MDPV (1-4 mg/kg) on pharmacokinetics, biodistribution and metabolism, acute effects on thermoregulation under isolated and aggregated conditions, locomotion (open field) and sensory gating (prepulse inhibition, PPI). All studies used male Wistar rats. Pharmacokinetics after single dose of 2 mg/kg MDPV was measured over 6 h in serum, brain and lungs...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29739408/-care-and-prevent-rationale-for-investigating-skin-and-soft-tissue-infections-and-aa-amyloidosis-among-people-who-inject-drugs-in-london
#19
M Harris, R Brathwaite, Catherine R McGowan, D Ciccarone, G Gilchrist, M McCusker, K O'Brien, J Dunn, J Scott, V Hope
BACKGROUND: Skin and soft tissue infections (SSTIs) are a leading cause of morbidity and mortality among people who inject drugs (PWID). International data indicate up to one third of PWID have experienced an SSTI within the past month. Complications include sepsis, endocarditis and amyloid A (AA) amyloidosis. AA amyloidosis is a serious sequela of chronic SSTI among PWID. Though there is a paucity of literature reporting on AA amyloidosis among PWID, what has been published suggests there is likely a causal relationship between AA amyloidosis and injecting-related SSTI...
May 8, 2018: Harm Reduction Journal
https://www.readbyqxmd.com/read/29739400/prevalence-of-hepatitis-c-virus-infection-among-prisoners-in-iran-a-systematic-review-and-meta-analysis
#20
REVIEW
Masoud Behzadifar, Hasan Abolghasem Gorji, Aziz Rezapour, Nicola Luigi Bragazzi
BACKGROUND: Hepatitis C virus (HCV) is one of the major public health problems both in developed and developing countries. Prison represents a high-risk environment for prisoners, in that it is characterized by high-risk behaviors such as injecting drug use (IDU), tattooing, unprotected sexual intercourses, or sharing syringes. The aim of this study was to quantitatively evaluate the prevalence of HCV among Iranian prisoners conducting a systematic review and meta-analysis. METHODS: We searched different scholarly databases including Embase, PubMed/MEDLINE, ISI/Web of Sciences, the Cochrane library, Scopus, CINAHL, and PsycINFO as well as Iranian bibliographic thesauri (namely, Barakatns, MagIran, and SID) up to December 2017...
May 9, 2018: Harm Reduction Journal
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