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https://www.readbyqxmd.com/read/28351060/blood-pressure-variability-in-obstructive-sleep-apnoea-data-from-4-randomised-controlled-cpap-withdrawal-trials
#1
Franziska Lettau, Esther I Schwarz, John R Stradling, Malcolm Kohler
BACKGROUND: Increased daytime blood pressure variability (BPV) is associated with cardiovascular risk. Preliminary data suggest that obstructive sleep apnoea (OSA) might contribute to increased daytime BPV. OBJECTIVE: The aim of this study was to evaluate the effect of continuous positive airway pressure (CPAP) therapy withdrawal on daytime BPV. METHODS: A total of 183 patients previously diagnosed with OSA and treated with CPAP were randomised to either continue or withdraw from CPAP within 4 trials...
March 29, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28351022/reference-values-and-factors-associated-with-musculoskeletal-symptoms-in-healthy-adolescents-and-adults
#2
Jennifer N Baldwin, Marnee J McKay, Niamh Moloney, Claire E Hiller, Elizabeth J Nightingale, Joshua Burns
BACKGROUND: Insufficient attention has been given to individuals who report musculoskeletal symptoms yet experience minimal disability. OBJECTIVES: To examine musculoskeletal symptoms among healthy individuals, and compare demographic, psychological and physical factors between individuals with and without symptoms. DESIGN: Cross-sectional observational study. METHOD: Data were from the 1000 Norms Project which recruited 1000 individuals aged 3-101 years...
March 23, 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28350777/understanding-brain-reorganization-in-infants-with-perinatal-stroke-through-neuroexcitability-and-neuroimaging
#3
Chao-Ying Chen, Michael Georgieff, Jed Elison, Mo Chen, James Stinear, Bryon Mueller, Raghavendra Rao, Kyle Rudser, Bernadette Gillick
PURPOSE: The primary aim of this proposed study is to evaluate brain reorganization patterns in infants with perinatal stroke between 3 and 5 months of age using transcranial magnetic stimulation and magnetic resonance imaging, with the addition of the General Movements Assessment. A secondary aim is to demonstrate feasibility and safety of infant-appropriate brain assessment protocols. METHODS: Ten infants with perinatal stroke will be enrolled. In this exploratory study, infants will first receive magnetic resonance imaging scanning during natural sleep to examine their corticospinal tract integrity...
April 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/28350759/resveratrol-supplementation-reduces-pain-experience-by-postmenopausal-women
#4
Rachel H X Wong, Hamish M Evans, Peter R C Howe
OBJECTIVE: Pain is a common complaint among postmenopausal women. It has been postulated that vascular dysfunction caused by estrogen decline at menopause plays a key role in the initiation and progression of degradative joint disease, namely age-related osteoarthritis. We evaluated whether supplementation with resveratrol, a phytoestrogen, could improve aspects of well-being such as chronic pain that is commonly experienced by postmenopausal women. METHODS: A 14-week randomized, double-blind, placebo-controlled intervention with trans-resveratrol (75 mg, twice daily) was conducted in 80 healthy postmenopausal women...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28350680/airway-and-feeding-outcomes-of-mandibular-distraction-tongue-lip-adhesion-and-conservative-management-in-pierre-robin-sequence-a-prospective-study
#5
Ibrahim Khansa, Courtney Hall, Lauren L Madhoun, Mark Splaingard, Adriane Baylis, Richard E Kirschner, Gregory D Pearson
BACKGROUND: Pierre Robin sequence is characterized by mandibular retrognathia and glossoptosis resulting in airway obstruction and feeding difficulties. When conservative management fails, mandibular distraction osteogenesis or tongue-lip adhesion may be required to avoid tracheostomy. The authors' goal was to prospectively evaluate the airway and feeding outcomes of their comprehensive approach to Pierre Robin sequence, which includes conservative management, mandibular distraction osteogenesis, and tongue-lip adhesion...
April 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28350442/engineered-polymer-transferrin-conjugates-as-self-assembling-targeted-drug-delivery-systems
#6
Hiteshri Makwana, Francesca Mastrotto, Johannes Pall Magnusson, Darrell Sleep, Joanna Hay, Karl J Nicholls, Stephanie Allen, Cameron Alexander
Polymer-protein conjugates can be engineered to self-assemble into discrete and well-defined drug delivery systems which combine the advantages of receptor targeting and controlled drug release. We designed specific conjugates of the iron-binding and transport protein, transferrin (Tf), to combine the advantages of this serum-stable protein as a targeting agent for cancer cells with self-assembling polymers to act as carriers of cytotoxic drugs. Tf variants were expressed with cysteine residues at sites spanning different regions of the protein surface and the polymer conjugates grown from these variants were compared with polymer conjugates grown from non-selectively derivatised sites on native Tf...
March 28, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28346681/obstructive-sleep-apnea-and-postoperative-complications-among-patients-undergoing-gynecologic-oncology-surgery
#7
Olumuyiwa A Bamgbade, Rong R Khaw, Raisah S Sawati, Cathrine M Holland
OBJECTIVE: To investigate the prevalence of obstructive sleep apnea (OSA), physiological or risk factors associated with OSA, and OSA-associated postoperative complications among patients undergoing gynecologic oncology surgery. METHODS: A prospective observational study was done of gynecologic oncology patients undergoing abdominal surgery at a center in the UK between August 2009 and January 2013. All patients underwent perioperative sleep oximetry for the diagnosis of OSA...
March 27, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28346652/treatment-success-with-titratable-thermoplastic-mandibular-advancement-devices-for-obstructive-sleep-apnea-a-comparison-of-patient-characteristics
#8
Tang-Chuan Wang, Yung-An Tsou, Yi-Fan Wu, Chia-Chang Huang, Wesley Wen-Yang Lin, Yu-Fen Li, Michael Yuan-Chien Chen, Chih-Jaan Tai, Ming-Hsui Tsai
A titratable thermoplastic mandibular advancement device (MAD) is clearly an effective treatment option in some patients with obstructive sleep apnea (OSA). Determining which patients may be more likely to respond to treatment with thermoplastic MADs and to adhere to treatment would be of obvious clinical relevance. This was an experimental descriptive study (N = 60). Patients with OSA were instructed to wear a titratable thermoplastic MAD for 3 months. Treatment success was defined as a ≥50% reduction from baseline in the apnea-hypopnea index (AHI) or AHI <10 when wearing MAD...
March 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28346639/unusual-case-of-sleep-apnea-in-a-child
#9
Lisa Duffy, Anita Jeyakumar
No abstract text is available yet for this article.
March 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28346384/intensive-sleep-re-training-from-bench-to-bedside
#10
REVIEW
Leon Lack, Hannah Scott, Gorica Micic, Nicole Lovato
Intensive sleep re-training is a promising new therapy for chronic insomnia. Therapy is completed over a 24-h period during a state of sleep deprivation. Improvements of sleep and daytime impairments are comparable to the use of stimulus control therapy but with the advantage of a rapid reversal of the insomnia. The initial studies have been laboratory based and not readily accessible to the patient population. However, new smart phone technology, using a behavioral response to external stimuli as a measure of sleep/wake state instead of EEG determination of sleep, has made this new therapy readily available...
March 27, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28346164/affiliative-interpersonal-behaviors-during-stress-are-associated-with-sleep-quality-and-presleep-arousal-in-young-healthy-adults
#11
Heather E Gunn, Kenneth L Critchfield, Julia E Mackaronis, Holly K Rau, Matthew R Cribbet, Wendy M Troxel, Paula G Williams
OBJECTIVES: This study examined the association between stress-related interpersonal behaviors, presleep arousal (PSA), and sleep quality. METHODS: Sixty-four participants (53% female) described a recent stressful interpersonal event that was coded for overall degree of affiliation (warmth vs hostility) and autonomy (independence vs interdependence). Cognitive and somatic PSA and sleep quality were examined using regression with affiliation and autonomy scores as predictors...
April 2017: Sleep Health
https://www.readbyqxmd.com/read/28346163/sleep-and-mental-health-the-moderating-role-of-perceived-adolescent-parent-attachment
#12
Kelly M Tu, Brian T Marks, Mona El-Sheikh
OBJECTIVE: The present study investigated whether the effects of sleep duration and quality on adolescent adjustment were moderated by perceived attachment to mothers and fathers. DESIGN: The study used a cross-sectional design. SETTING: Participants were recruited from small town and semirural communities in Alabama. PARTICIPANTS: Participants were 106 adolescents (mean age=13.61 years, SD=.73; 55% girls; 28% African American, 72% European American) and their parents...
April 2017: Sleep Health
https://www.readbyqxmd.com/read/28346162/household-chaos-and-sleep-disturbing-behavior-of-family-members-results-of-a-pilot-study-of-african-american-early-adolescents
#13
James C Spilsbury, Sanjay R Patel, Nathan Morris, Aida Ehayaei, Stephen S Intille
BACKGROUND: Although disorganized, chaotic households have been linked to poorer sleep outcomes, how household chaos actually manifests itself in the behaviors of others around the bedtime of a child or adolescent is not well understood. OBJECTIVE: To determine whether household chaos was associated with specific, nightly sleep-disturbing activities of adolescents' family members. DESIGN: Longitudinal study. PARTICIPANTS: Twenty-six African American or multiethnic early adolescent (ages 11-12 years) and parent dyads, recruited from local schools and social-service agencies in greater Cleveland, OH...
April 2017: Sleep Health
https://www.readbyqxmd.com/read/28346161/gender-differences-in-sleep-hygiene-practices-and-sleep-quality-in-new-zealand-adolescents-aged-15-to-17-years
#14
Barbara C Galland, Andrew R Gray, Jonathan Penno, Claire Smith, Carmen Lobb, Rachael W Taylor
AIM: To examine, in a nationwide sample of New Zealand adolescents, self-reported sleep hygiene, and specifically evening technology and caffeine use, and body mass index, in relation to sleep quality. DESIGN: Cross-sectional survey. PARTICIPANTS: A total of 692 adolescents (59% girls), predominantly European (78%), with an average age of 16 years 9 months were recruited through schools, community advertising, and social media. MEASURES: All participants completed the Pittsburgh Sleep Quality Index and Adolescent Sleep Hygiene Scale online, and questions about their height, weight, evening technology use, and caffeine consumption...
April 2017: Sleep Health
https://www.readbyqxmd.com/read/28346160/sleep-under-a-mother-s-protective-gaze
#15
EDITORIAL
Meir H Kryger, Isabella Siegel
No abstract text is available yet for this article.
April 2017: Sleep Health
https://www.readbyqxmd.com/read/28346159/using-actigraphy-feedback-to-improve-sleep-in-soldiers-an-exploratory-trial
#16
Amy B Adler, Brian C Gunia, Paul D Bliese, Paul Y Kim, Matthew L LoPresti
OBJECTIVES: The objective of this study was to assess the impact of wearing an actigraph and receiving personalized feedback on the sleep of a high-risk occupational group: United States soldiers recently returned from a combat deployment. DESIGN: Following a baseline survey with a full sample, a subsample of soldiers wore an actigraph, received feedback, and completed a brief survey. Two months later, the full sample completed a follow-up survey. The actigraph intervention involved wearing an actigraph for 3 weeks and then receiving a personalized report about sleep patterns and an algorithm-based estimate of cognitive functioning derived from individual sleep patterns...
April 2017: Sleep Health
https://www.readbyqxmd.com/read/28346158/delayed-high-school-start-times-later-than-8-30am-and-impact-on-graduation-rates-and-attendance-rates
#17
Pamela Malaspina McKeever, Linda Clark
OBJECTIVES: The first purpose of this study was to investigate changes in high school graduation rates with a delayed school start time of later than 8:30am. The second aim of the study was to analyze the association between a delayed high school start time later than 8:30am and attendance rates. DESIGN: In the current study, a pre-post design using a repeated-measures analysis of variance was used to examine changes in attendance and graduation rates 2 years after a delayed start was implemented...
April 2017: Sleep Health
https://www.readbyqxmd.com/read/28346157/earlier-school-start-times-are-associated-with-higher-rates-of-behavioral-problems-in-elementary-schools
#18
Peggy S Keller, Lauren R Gilbert, Eric A Haak, Shuang Bi, Olivia A Smith
BACKGROUND: Early school start times may curtail children's sleep and inadvertently promote sleep restriction. The current study examines the potential implications for early school start times for behavioral problems in public elementary schools (student ages 5-12 years) in Kentucky. METHOD: School start times were obtained from school Web sites or by calling school offices; behavioral and disciplinary problems, along with demographic information about schools, were obtained from the Kentucky Department of Education...
April 2017: Sleep Health
https://www.readbyqxmd.com/read/28346156/association-of-sleep-characteristics-with-cardiovascular-and-metabolic-risk-factors-in-a-population-sample-the-chicago-area-sleep-study
#19
Samantha E Montag, Kristen L Knutson, Phyllis C Zee, Jeffrey J Goldberger, Jason Ng, Kwang-Youn A Kim, Mercedes R Carnethon
OBJECTIVES: To investigate the association of sleep characteristics with prevalent hypertension, diabetes, and obesity in a multiethnic cohort. DESIGN: This study used a population-based cross-sectional study design. SETTING: Participants were recruited between 2009 and 2011 from Chicago, Illinois, and the surrounding suburbs. PARTICIPANTS: Participants were 492 adults aged 35 to 64years who self-reported as white, black, Hispanic, or Asian and who had a low likelihood of sleep apnea based on the apnea screening questionnaires and 1 night of apnea screening using an in-home device (apnea hypopnea index <15 or oxygen desaturation index <10)...
April 2017: Sleep Health
https://www.readbyqxmd.com/read/28346155/objectively-measured-sleep-and-health-related-quality-of-life-in-older-adults-with-type-2-diabetes-a-cross-sectional-study-from-the-alberta-s-caring-for-diabetes-study
#20
Steven T Johnson, Danielle Thiel, Fatima Al Sayah, Clark Mundt, Weiyu Qiu, Matthew P Buman, Jeff K Vallance, Jeffrey A Johnson
BACKGROUND AND AIM: Sleep is an important behavior for metabolic control and mental health in type 2 diabetes. The aim was to examine the relationship of objective estimates of sleep quantity and quality with health-related quality of life (HRQL) in adults with type 2 diabetes. MATERIALS AND METHODS: Participants completed a survey where HRQL was measured using the EQ-5D-5 L index score, and the SF-12 v2, which provides physical and mental composite summary (PCS and MCS) scores...
April 2017: Sleep Health
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