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https://www.readbyqxmd.com/read/28798414/comparison-of-neonatal-outcomes-following-progesterone-use-during-ovarian-stimulation-with-frozen-thawed-embryo-transfer
#1
Xiuxian Zhu, Hongjuan Ye, Yonglun Fu
Progesterone soft capsules (brand name: Utrogestan) were demonstrated to be an effective oral alternative to prevent premature LH surges both in normal-ovulatory and polycystic ovarian syndrome (PCOS) patients. However, its safety in terms of neonatal outcomes is unclear. To evaluate whether Utrogestan use increase the risk of adverse neonatal outcomes compared with short protocol in patients undergoing IVF/ICSI treatments in combination with frozen-thawed embryo transfer (FET), we performed a retrospective analysis including 1008 FET cycles, with embryos originated from either Utrogestan + hMG protocol (n = 499), or short protocol (n = 509), which led to 546 live-born infants...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28798302/low-voltage-high-performance-organic-field-effect-transistors-based-on-2d-crystalline-molecular-semiconductors
#2
Qijing Wang, Sai Jiang, Jun Qian, Lei Song, Lei Zhang, Yujia Zhang, Yuhan Zhang, Yu Wang, Xinran Wang, Yi Shi, Youdou Zheng, Yun Li
Two dimensional (2D) molecular crystals have attracted considerable attention because of their promising potential in electrical device applications, such as high-performance field-effect transistors (FETs). However, such devices demand high voltages, thereby considerably increasing power consumption. This study demonstrates the fabrication of organic FETs based on 2D crystalline films as semiconducting channels. The application of high-κ oxide dielectrics allows the transistors run under a low operating voltage (-4 V)...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28797948/a-scanning-probe-mounted-on-a-field-effect-transistor-characterization-of-ion-damage-in-si
#3
Kumjae Shin, Hoontaek Lee, Min Sung, Sang Hoon Lee, Hyunjung Shin, Wonkyu Moon
We have examined the capabilities of a Tip-On-Gate of Field-Effect Transistor (ToGoFET) probe for characterization of FIB-induced damage in Si surface. A ToGoFET probe is the SPM probe which the Field Effect Transistor(FET) is embedded at the end of a cantilever and a Pt tip was mounted at the gate of FET. The ToGoFET probe can detect the surface electrical properties by measuring source-drain current directly modulated by the charge on the tip. In this study, a Si specimen whose surface was processed with Ga+ ion beam was prepared...
July 24, 2017: Micron: the International Research and Review Journal for Microscopy
https://www.readbyqxmd.com/read/28797584/long-term-outcomes-of-frozen-elephant-trunk-for-type-a-aortic-dissection-in-patients-with-marfan-syndrome
#4
Wei-Guo Ma, Wei Zhang, Jun-Ming Zhu, Bulat A Ziganshin, Ai-Hua Zhi, Jun Zheng, Yong-Min Liu, John A Elefteriades, Li-Zhong Sun
OBJECTIVE: The use of the frozen elephant trunk (FET) technique for repair of type A aortic dissection (TAAD) in Marfan syndrome (MFS) is controversial. We seek to evaluate the efficacy of FET and total arch replacement (TAR) for TAAD in patients with MFS. METHODS: The early and long-term outcomes were analyzed for 106 patients with MFS (mean age, 34.5 ± 9.7 years) undergoing FET + TAR for TAAD. RESULTS: Operative mortality was 6.6% (7 of 106)...
June 16, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28795845/analysis-of-embryo-intactness-and-developmental-potential-following-slow-freezing-and-vitrification
#5
Lan Yu, Chanwei Jia, Yonglian Lan, Rui Song, Liying Zhou, Ying Li, Yu Liang, Shuyu Wang
The aim of this study was to identify the parameters that are related to intactness and developmental potential of a day 3 embryo after warming to improve the selection criteria used to cryopreserve and transfer embryos. We also sought to compare slow freezing and vitrification methods of cryopreservation and to evaluate the viability of non-intact embryos. Embryos warmed following slow freezing (n=220) or vitrification (n=522) were divided into 3 groups according to the proportion of surviving blastomeres (I<50%; II=50-99%; and III=100%)...
August 10, 2017: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/28795534/graphene-field-effect-transistors-for-the-sensitive-and-selective-detection-of-escherichia-coli-using-pyrene-tagged-dna-aptamer
#6
Guangfu Wu, Ziwen Dai, Xin Tang, Zihong Lin, Pik Kwan Lo, Meyya Meyyappan, King Wai Chiu Lai
This study reports biosensing using graphene field-effect transistors with the aid of pyrene-tagged DNA aptamers, which exhibit excellent selectivity, affinity, and stability for Escherichia coli (E. coli) detection. The aptamer is employed as the sensing probe due to its advantages such as high stability and high affinity toward small molecules and even whole cells. The change of the carrier density in the probe-modified graphene due to the attachment of E. coli is discussed theoretically for the first time and also verified experimentally...
August 10, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28794815/detection-of-c-reactive-protein-on-an-integrated-microfluidic-system-by-utilizing-field-effect-transistors-and-aptamers
#7
Wei-Chieh Kao, Yen-Wen Chen, Chia-Ho Chu, Wen-Hsin Chang, Shu-Chu Shiesh, Yu-Lin Wang, Gwo-Bin Lee
Cardiovascular diseases (CVDs) cause more than 17 × 10(6) deaths worldwide on a yearly basis. Early diagnosis of CVDs is therefore of great need. The C-reactive protein (CRP) is an important biomarker for analyzing the risks of CVDs. In this work, CRP-specific aptamers with high sensitivity and specificity and field-effect-transistor (FET) devices were used to recognize and detect CRP by using an integrated microfluidic system automatically while consuming less volumes of reagents and samples (about 5 μm)...
July 2017: Biomicrofluidics
https://www.readbyqxmd.com/read/28793277/o-2-18-f-fluoroethyl-l-tyrosine-18-f-fet-uptake-in-insulinoma-first-results-from-a-xenograft-mouse-model-and-from-human
#8
Alessio Imperiale, Frédéric Boisson, Guillaume Kreutter, Bernard Goichot, Izzie Jacques Namer, Philippe Bachellier, Patrice Laquerriere, Laurence Kessler, Patrice Marchand, David Brasse
INTRODUCTION: Herein we have evaluated the uptake of O-(2-(18)F-fluoroethyl)-l-tyrosine ((18)F-FET) in insulinoma in comparison with those of 6-(18)F-fluoro-3,4-dihydroxy-l-phenylalanine ((18)F-FDOPA) providing first data from both murine xenograft model and one patient with proved endogenous hyperinsulinemic hypoglycemia. METHODS: Dynamic (18)F-FET and carbidopa-assisted (18)F-FDOPA PET were performed on tumor-bearing nude mice after subcutaneous injection of RIN-m5F murine beta cells and on a 30-year-old man with type-1 multiple endocrine neoplasia and hyperinsulinemic hypoglycemia defined by a positive fasting test...
July 12, 2017: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/28791461/expression-of-h19-imprinted-gene-in-patients-with-repeated-implantation-failure-during-the-window-of-implantation
#9
Hong Zeng, Xiuli Fan, Nenghui Liu
PURPOSE: To detect the expression level of imprinted gene H19 in the endometrium of patients with repeated implantation failure (RIF) who were undergoing in vitro fertilization and embryo transfer (IVF-ET) or frozen embryo transfer (FET). METHODS: Patients who underwent IVF/FET in Reproductive Medicine Center of Xiangya Hospital during April 1, 2015 to October 31, 2015 were chosen. The endometrium was collected from patients with repeated implantation failure during mid-luteal phase...
August 8, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28774682/methods-for-molecular-imaging-of-brain-tumours-in-a-hybrid-mr-pet-context-water-content-t2%C3%A2-diffusion-indices-and-fet-pet
#10
A M Oros-Peusquens, R Loução, M Zimmermann, K-J Langen, N J Shah
The aim of this study is to present and evaluate a multiparametric and multi-modality imaging protocol applied to brain tumours and investigate correlations between these different imaging measures (R1.1). In particular, we describe a method for rapid, non-invasive, quantitative imaging of water content of brain tissue, based on a single multiple-echo gradient-echo (mGRE) acquisition. We include in the processing a method for noise reduction of the multi-contrast data based on Principal Component Analysis (PCA)...
July 31, 2017: Methods: a Companion to Methods in Enzymology
https://www.readbyqxmd.com/read/28773173/the-property-preparation-and-application-of-topological-insulators-a-review
#11
REVIEW
Wenchao Tian, Wenbo Yu, Jing Shi, Yongkun Wang
Topological insulator (TI), a promising quantum and semiconductor material, has gapless surface state and narrow bulk band gap. Firstly, the properties, classifications and compounds of TI are introduced. Secondly, the preparation and doping of TI are assessed. Some results are listed. (1) Although various preparation methods are used to improve the crystal quality of the TI, it cannot reach the industrialization. Fermi level regulation still faces challenges; (2) The carrier type and lattice of TI are affected by non-magnetic impurities...
July 17, 2017: Materials
https://www.readbyqxmd.com/read/28772592/low-temperature-solution-processed-transparent-zinc-oxide-based-thin-film-transistors-for-sensing-various-solvents
#12
Hsin-Chiang You, Cheng-Jyun Wang
A low temperature solution-processed thin-film transistor (TFT) using zinc oxide (ZnO) film as an exposed sensing semiconductor channel was fabricated to detect and identify various solution solvents. The TFT devices would offer applications for low-cost, rapid and highly compatible water-soluble detection and could replace conventional silicon field effect transistors (FETs) as bio-sensors. In this work, we demonstrate the utility of the TFT ZnO channel to sense various liquids, such as polar solvents (ethanol), non-polar solvents (toluene) and deionized (DI) water, which were dropped and adsorbed onto the channel...
February 26, 2017: Materials
https://www.readbyqxmd.com/read/28770993/real-time-monitoring-of-insulin-using-a-graphene-field-effect-transistor-aptameric-nanosensor
#13
Zhuang Hao, Yibo Zhu, Xuejun Wang, Pavana Rotti, Christopher DiMarco, Scott Tyler, Xuezeng Zhao, John F Engelhardt, James C Hone, Qiao Lin
This paper presents an approach to the real-time, label-free, specific and sensitive detection of insulin using a graphene aptameric nanosensor. The nanosensor is configured as a field effect transistor (FET), whose graphene conducting channel is functionalized with a guanine-rich IGA3 aptamer. The negatively charged aptamer folds into a compact and stable anti-parallel or parallel G-quadruplex conformation upon binding with insulin, resulting in a change in the carrier density of graphene and thus its electrical conductance...
August 3, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28770923/exploring-the-upper-limit-of-single-walled-carbon-nanotube-purity-by-multiple-cycle-aqueous-two-phase-separation
#14
Li Wei, Benjamin S Flavel, Wenshan Li, Ralph Krupke, Yuan Chen
Ultrahigh purity semiconducting single-walled carbon nanotubes (S-SWCNTs) are required for high-performance transistors. Aqueous two-phase (ATP) separation is an attractive method to obtain such SWCNTs due to its simplicity and scalability. This work targeted two questions; namely what is the upper limit of S-SWCNT purity that can be achieved by multiple cycles of ATP separation from the most commonly used polyethylene glycol and dextran system and how accurately can commonly used methods characterize the improvement in purity? SWCNT purity in nanotube dispersions obtained by multi-cycle ATP separation (2, 4, 6 and 8 cycles) was evaluated by three methods, including UV-vis-NIR absorption spectroscopy analysis, performance of thin-film field effect transistors (FETs) prepared by drop casting and short-channel FET devices prepared by dielectrophoresis deposition...
August 3, 2017: Nanoscale
https://www.readbyqxmd.com/read/28765227/determination-of-an-optimal-pharmacokinetic-model-of-18-f-fet-for-quantitative-applications-in-rat-brain-tumors
#15
Marie Anne Richard, Jérémie P Fouquet, Réjean Lebel, Martin Lepage
O-(2-(18)F-fluoroethyl)-l-tyrosine ((18)F-FET) is a radiolabeled artificial amino acid used in PET for tumor delineation and grading. The present study compares different kinetic models to determine which are more appropriate for (18)F-FET in rats. Methods: Rats were implanted with F98 glioblastoma cells in the right hemisphere and scanned 9-15 d later. PET data were acquired during 50 min after a 1-min bolus of (18)F-FET. Arterial blood samples were drawn for arterial input function determination. Two compartmental pharmacokinetic models were tested: the 2-tissue model and the 1-tissue model...
August 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28760794/comparison-of-a-freeze-all-strategy-including-gnrh-agonist-trigger-versus-a-fresh-transfer-strategy-including-hcg-trigger-in-assisted-reproductive-technology-art-a-study-protocol-for-a-randomised-controlled-trial
#16
Sacha Stormlund, Kristine Løssl, Anne Zedeler, Jeanette Bogstad, Lisbeth Prætorius, Henriette Svarre Nielsen, Mona Bungum, Sven O Skouby, Anne Lis Mikkelsen, Anders Nyboe Andersen, Christina Bergh, Peter Humaidan, Anja Pinborg
INTRODUCTION: Pregnancy rates after frozen embryo transfer (FET) have improved in recent years and are now approaching or even exceeding those obtained after fresh embryo transfer. This is partly due to improved laboratory techniques, but may also be caused by a more physiological hormonal and endometrial environment in FET cycles. Furthermore, the risk of ovarian hyperstimulation syndrome is practically eliminated in segmentation cycles followed by FET and the use of natural cycles in FETs may be beneficial for the postimplantational conditions of fetal development...
July 31, 2017: BMJ Open
https://www.readbyqxmd.com/read/28760465/elective-aortic-arch-repair-factors-influencing-neurologic-outcome-in-791-patients
#17
Mariano Cefarelli, Giacomo Murana, Giuseppina G Surace, Sebastiano Castrovinci, Giuliano Jafrancesco, Johannes Christiaan Kelder, Patrick Klein, Uday Sonker, Wim J Morshuis, Robin H Heijmen
BACKGROUND: The aim of this study was to determine perioperative factors influencing neurologic outcome in a single-center cohort of patients undergoing elective aortic arch operations. METHODS: From January 2005 to June 2015, 791 consecutive patients received open aortic arch operations with either antegrade selective cerebral perfusion (ASCP) (636 patients [80.4%]) or deep hypothermic circulatory arrest (DHCA) (155 patients [19.6%]). Main indications were degenerative aneurysm (85%) and chronic postdissection aneurysm (9...
July 28, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28758721/polymer-free-electronic-grade-aligned-semiconducting-carbon-nanotube-array
#18
Yongho Joo, Gerald J Brady, Catherine Kanimozhi, Jaehyoung Ko, Matthew J Shea, Michael T Strand, Michael S Arnold, Padma Gopalan
Conjugated polymers are used commonly to selectively sort semiconducting carbon nanotubes (S-CNTs) from their metallic counterparts in organic solvents. The polymer-wrapped S-CNTs can be easily processed from organic solvents into arrays of CNTs for scalable device fabrication. Though the conjugated polymers are essential for sorting and device fabrication, it is highly desirable to remove them completely as they limit the electronic properties of the device. Here, we use a commercially available polymer, namely, poly[(9,9-dioctylfluorenyl-2,7-diyl)-alt-co-(6,6'-(2,2'-bipyridine))] (PFO-BPy), to sort large-diameter S-CNTs with ultrahigh selectivity and fabricate CNT-array-based field effect transistors (FETs) via a floating evaporative self-assembly (FESA) process...
August 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28758671/switchable-changes-in-the-conductance-of-single-walled-carbon-nanotube-networks-on-exposure-to-water-vapour
#19
Gwyn P Evans, David J Buckley, Neal T Skipper, Ivan P Parkin
We have discovered that wrapping single-walled carbon nanotubes (SWCNTs) with ionic surfactants induces a switch in the conductance-humidity behaviour of SWCNT networks. Residual cationic vs. anionic surfactant induces a respective increase or decrease in the measured conductance across the SWCNT networks when exposed to water vapour. The magnitude of this effect was found to be dependent on the thickness of the deposited SWCNT films. Previously, chemical sensors, field effect transistors (FETs) and transparent conductive films (TCFs) have been fabricated from aqueous dispersions of surfactant functionalised SWCNTs...
July 31, 2017: Nanoscale
https://www.readbyqxmd.com/read/28758558/acute-debakey-type-i-dissection-repair-using-frozen-elephant-trunk-the-cleveland-clinic-technique
#20
Muhammad Aftab, Ryan Plichta, Eric E Roselli
Over the past 3 decades, the standard surgical management for acute DeBakey type I aortic dissection has not significantly changed. Most patients undergo ascending aortic replacement with an interposition graft under hypothermic circulatory arrest with selective root replacement. Nevertheless, with the improvement in overall patient care, acute surgical outcomes continue to improve. The frozen elephant trunk (FET) technique was introduced as a modification to conventional elephant trunk to treat extensive degenerative and chronic dissecting aneurysms involving the aortic arch and the proximal descending aorta...
September 2017: Seminars in Cardiothoracic and Vascular Anesthesia
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