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Chloe Higgins, Martin Healey, Sameer Jatkar, Beverley Vollenhoven
BACKGROUND: There is currently limited evidence available regarding ideal timing for frozen embryo transfer (FET). Demonstrating that delaying FETs has few clinical benefits would allow patients to proceed with FET at their earliest convenience. AIMS: To examine whether the time interval between stimulation cycle and subsequent FET affects pregnancy and live birth rates. MATERIALS AND METHODS: This retrospective cohort study, based in a multi-site private in vitro fertilisation (IVF) clinic categorised women into two groups: those having FET cycles administered within 25-35 days or 50-70 days of IVF stimulation cycle and embryo freeze...
September 14, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
Meng-Meng Xiao, Chenguang Qiu, Zhiyong Zhang, Lianmao Peng
Direct growth of ultra-thin gate dielectric layer with high uniformity and high quality on graphene remains a challenge for developing graphene-based transistors due to the chemical inert surface properties of graphene. Here we develop a method to realize atomic-layer-deposition (ALD) growth of ultra-thin high-k dielectric layer on graphene through pre-modified graphene surface using electron beam irradiation. An amorphous carbon layer induced by electron beam scanning is formed on graphene, and then acts as seed for ALD growth of high-k dielectrics...
September 13, 2017: ACS Applied Materials & Interfaces
G He, J Nathawat, C-P Kwan, H Ramamoorthy, R Somphonsane, M Zhao, K Ghosh, U Singisetti, N Perea-López, C Zhou, A L Elías, M Terrones, Y Gong, X Zhang, R Vajtai, P M Ajayan, D K Ferry, J P Bird
The high field phenomena of inter-valley transfer and avalanching breakdown have long been exploited in devices based on conventional semiconductors. In this Article, we demonstrate the manifestation of these effects in atomically-thin WS2 field-effect transistors. The negative differential conductance exhibits all of the features familiar from discussions of this phenomenon in bulk semiconductors, including hysteresis in the transistor characteristics and increased noise that is indicative of travelling high-field domains...
September 12, 2017: Scientific Reports
Amiya K Ghosh, Martin O'Brien, Theresa Mau, Raymond Yung
Adipose tissue (AT) inflammation is a central mechanism for metabolic dysfunction in both diet-induced obesity and age-associated obesity. Studies in diet-induced obesity have characterized the role of Fetuin A (Fet A) in Free Fatty Acids (FFA)-mediated TLR4 activation and adipose tissue inflammation. However, the role of Fet A & TLR4 in aging-related adipose tissue inflammation is unknown. In the current study, analysis of epidymymal fat pads of C57/Bl6 male mice, we found that, in contrast to data from diet-induced obesity models, adipose tissue from aged mice have normal Fet A and TLR4 expression...
September 7, 2017: Aging
Yue Li, Kailiang Zhang, Fang Wang, Yulin Feng, Yi Li, Yemei Han, Dengxuan Tang, Baojun Zhang, H-S Philip Wong
Atomically thin, two-dimensional material molybdenum diselenide (MoSe2), has been shown to exhibit significant potential for diverse applications. The intrinsic bandgap of MoSe2 allows it to overcome the shortcomings of the zero-bandgap graphene, while its higher electron mobilities when compared to molybdenum disulfide (MoS2) make it more appropriate for practical devices in electronics and optoelectronics. However, its controlled growth has been an ongoing challenging for investigations and practical applications of the material...
September 12, 2017: ACS Applied Materials & Interfaces
Richard Janissen, Prasana K Sahoo, Clelton A Santos, Aldeliane M da Silva, Antonio A G von Zuben, Denio E P Souto, Alexandre D T Costa, Paola Celedon, Nilson I T Zanchin, Diogo B Almeida, Douglas S Oliveira, Lauro T Kubota, Carlos Lenz Cesar, Anete Pereira de Souza, Monica Alonso Cotta
Electrically active field-effect transistors (FET) based biosensors are of paramount importance in life science applications, as they offer direct, fast, and highly sensitive label-free detection capabilities of several biomolecules of specific interest. In this work, we report a detailed investigation on surface functionalization and covalent immobilization of biomarkers using biocompatible ethanolamine and poly(ethylene glycol) derivate coatings - as compared to the conventional approaches using silica monoliths - in order to substantially increase both the sensitivity and molecular selectivity of nanowire-based FET biosensor platforms...
September 12, 2017: Nano Letters
Ruge Quhe, Yangyang Wang, Meng Ye, Qiaoxuan Zhang, Jie Yang, Pengfei Lu, Ming Lei, Jing Lu
Contact engineering is a possible solution to decrease the pervasive Schottky barrier in a two dimensional (2D) material transistor with bulk metal electrodes. In this paper, two kinds of typical van der Waals (vdW)-type electrical contacts (a 2D metal contact and a 2D material/bulk metal hybrid contact) in monolayer (ML) black phosphorus (BP) transistors are investigated by ab initio energy band calculations and quantum transport simulations. Compared with the traditional bulk metal Ni contact, the gate electrostatic control is significantly improved by using both 2D graphene and borophene electrodes featuring a decrease of 30-50% in the subthreshold swing and an increase by a factor of 4-7 in the on-state current due to the depressed metal induced gap states and reduced screening of the 2D metal electrodes to the gate...
September 12, 2017: Nanoscale
Farida Veliev, Zheng Han, Dipankar Kalita, Anne Briançon-Marjollet, Vincent Bouchiat, Cécile Delacour
The emergence of nanoelectronics applied to neural interfaces has started few decades ago, and aims to provide new tools for replacing or restoring disabled functions of the nervous systems as well as further understanding the evolution of such complex organization. As the same time, graphene and other 2D materials have offered new possibilities for integrating micro and nano-devices on flexible, transparent, and biocompatible substrates, promising for bio and neuro-electronics. In addition to many bio-suitable features of graphene interface, such as, chemical inertness and anti-corrosive properties, its optical transparency enables multimodal approach of neuronal based systems, the electrical layer being compatible with additional microfluidics and optical manipulation ports...
2017: Frontiers in Neuroscience
Rukiya Matsidik, Alessandro Luzio, Özge Askin, Daniele Fazzi, Alessandro Sepe, Ullrich Steiner, Hartmut Komber, Mario Caironi, Michael Sommer
The synthesis, characterization, and charge transport performance of novel copolymers PNDIFu2 made from alternating naphthalene diimide (NDI) and bifuran (Fu2) units are reported. Usage of potentially biomass-derived Fu2 as alternating repeat unit enables flattened polymer backbones due to reduced steric interactions between the imide oxygens and Fu2 units, as seen by density functional theory (DFT) calculations and UV-vis spectroscopy. Aggregation of PNDIFu2 in solution is enhanced if compared to the analogous NDI-bithiophene (T2) copolymers PNDIT2, occurring in all solvents and temperatures probed...
July 11, 2017: Chemistry of Materials: a Publication of the American Chemical Society
Meghnath Jaishi, Ranjit Pati
Catching the electron in action in real space inside a semiconductor Ge-Si core-shell nanowire field effect transistor (FET), which has been demonstrated (J. Xiang, W. Lu, Y. Hu, Y. Wu, H. Yan and C. M. Lieber, Nature, 2006, 441, 489) to outperform the state-of-the-art metal oxide semiconductor FET, is central to gaining unfathomable access into the origin of its functionality. Here, using a quantum transport approach that does not make any assumptions on electronic structure, charge, and potential profile of the device, we unravel the most probable tunneling pathway for electrons in a Ge-Si core-shell nanowire FET with orbital level spatial resolution, which demonstrates gate bias induced decoupling of electron transport between the core and the shell region...
September 7, 2017: Nanoscale
Wei Li, Hongxia Liu, Shulong Wang, Shupeng Chen, Qianqiong Wang
The larger volume of capacitor and higher leakage current of transistor have become the inherent disadvantages for the traditional one transistor (1T)-one capacitor (1C) dynamic random access memory (DRAM). Recently, the tunneling FET (TFET) is applied in DRAM cell due to the low off-state current and high switching ratio. The dual-gate TFET (DG-TFET) DRAM cell with the capacitorless structure has the superior performance-higher retention time (RT) and weak temperature dependence. But the performance of TFET DRAM cell is sensitive to programming condition...
September 6, 2017: Nanoscale Research Letters
Giuseppe Malafronte, Barbara Filosa
OBJECTIVE: to evaluate if calcified plaques adjacent to the perforation and marginal perforations are real contraindications to the fat graft myringoplasty. STUDY DESIGN: prospective study. METHODS: This study was conducted, from 1(st) January 2008 to 31 December 2015 at our Otolaryngology Department of S.G. Moscati Hospital. The investigation included 125 patients, 60 males and 65 females, affected by COM who have undergone fat graft myringoplasty between 01/01/2008 to 31/12/2011...
September 5, 2017: Clinical Otolaryngology
Jennifer F Knudtson, Courtney M Failor, Jonathan A Gelfond, Martin W Goros, Tiencheng Arthur Chang, Robert S Schenken, Randal D Robinson
OBJECTIVE: To assess the effect of assisted hatching (AH) on live-birth rates in a retrospective cohort of patients undergoing first-cycle, autologous frozen embryo transfer (FET). DESIGN: Longitudinal cohort using cycles reported to the Society for Assisted Reproductive Technology Clinic Outcomes Reporting System between 2004 and 2013. SETTING: Not applicable. PATIENT(S): Women who underwent first-cycle, autologous FET with (n = 70,738) and without (n = 80,795) AH reported from 2004 to 2013...
August 29, 2017: Fertility and Sterility
Otávio Pelegrino Rocha, Danielle Palma De Oliveira
Tannery effluents consist of a complex chemical composition not only limited to primary pollutants, which also require biological detection as these compounds may produce adverse effects. The fish embryo toxicity (FET) test with Danio rerio is an alternative method in hazard and risk assessment for determination of chemical-mediated effects. The aim of this investigation was to use the FET test to detect compounds and consequent effects in Brazilian tannery effluents. Samples were collected from the inlet and outlet of the effluent treatment plant at a tannery located in Restinga, São Paulo, Brazil...
September 1, 2017: Journal of Toxicology and Environmental Health. Part A
Zuocheng Zhang, Likai Li, Jason Horng, Nai Zhou Wang, Fangyuan Yang, Yijun Yu, Yu Zhang, Guorui Chen, Kenji Watanabe, Takashi Taniguchi, Xian Hui Chen, Feng Wang, Yuanbo Zhang
Energy bandgap largely determines the optical and electronic properties of a semiconductor. Variable bandgap therefore makes versatile functionality possible in a single material. In layered material black phosphorus, the bandgap can be modulated by the number of layers; as a result, few-layer black phosphorus has discrete bandgap values that are relevant for optoelectronic applications in the spectral range from red, in monolayer, to mid-infrared in the bulk limit. Here, we further demonstrate continuous bandgap modulation by mechanical strain applied through flexible substrates...
September 11, 2017: Nano Letters
Deshun Qu, Xiaochi Liu, Ming Huang, Changmin Lee, Faisal Ahmed, Hyoungsub Kim, Rodney S Ruoff, James Hone, Won Jong Yoo
A systematic modulation of the carrier type in molybdenum ditelluride (MoTe2 ) field-effect transistors (FETs) is described, through rapid thermal annealing (RTA) under a controlled O2 environment (p-type modulation) and benzyl viologen (BV) doping (n-type modulation). Al2 O3 capping is then introduced to improve the carrier mobilities and device stability. MoTe2 is found to be ultrasensitive to O2 at elevated temperatures (250 °C). Charge carriers of MoTe2 flakes annealed via RTA at various vacuum levels are tuned between predominantly pristine n-type ambipolar, symmetric ambipolar, unipolar p-type, and degenerate-like p-type...
August 28, 2017: Advanced Materials
Luca Di Marco, Davide Pacini, Alessandro Leone, Antonio Pantaleo, Giacomo Murana, Roberto Di Bartolomeo
The treatment of patients with extensive disease of the thoracic aorta represents a formidable challenge for the cardiovascular surgeon. The beginning of thoracic aortic endovascular aortic arch repair has promoted the development of different hybrid approaches as the frozen elephant trunk (FET) strategy, which includes classic arch replacement and antegrade stenting of the descending thoracic aorta. It represents an interesting approach for patients with extensive disease of the thoracic aorta, and its application has significantly increased over recent years...
September 2017: Giornale Italiano di Cardiologia
Fernando Zegers-Hochschild, Juan Enrique Schwarze, Javier A Crosby, Carolina Musri, Maria Teresa Urbina
Multinational data on assisted reproduction techniques undertaken in 2014 were collected from 159 institutions in 15 countries in Latin America. Treatments included IVF/ ICSI, FET, OD, PGD and fertility preservation (FP). 41.34% of IVF/ICSI cycles were performed in women aged 35 to 39 years and 23.35% in women aged 40 and older. After removing cases with total freezing, delivery rate per oocyte retrieval was 25.05% for ICSI and 27.41% for IVF. Multiple births included 20.78% twins and 0.92 % triplets and over...
September 1, 2017: JBRA Assisted Reproduction
Stephen Boandoh, Soo Ho Choi, Ji-Hoon Park, So Young Park, Seungho Bang, Mun Seok Jeong, Joo Song Lee, Hyeong Jin Kim, Woochul Yang, Jae-Young Choi, Soo Min Kim, Ki Kang Kim
High-quality and large-area molybdenum disulfide (MoS2 ) thin film is highly desirable for applications in large-area electronics. However, there remains a challenge in attaining MoS2 film of reasonable crystallinity due to the absence of appropriate choice and control of precursors, as well as choice of suitable growth substrates. Herein, a novel and facile route is reported for synthesizing few-layered MoS2 film with new precursors via chemical vapor deposition. Prior to growth, an aqueous solution of sodium molybdate as the molybdenum precursor is spun onto the growth substrate and dimethyl disulfide as the liquid sulfur precursor is supplied with a bubbling system during growth...
August 22, 2017: Small
Nupur Navlakha, Abhinav Kranti
The work reports on the use of a planar tri-gate Tunnel Field Effect Transistor (TFET) to operate as dynamic memory at 85 C with an enhanced Sense Margin (SM). The two symmetric gates (G1) aligned to the source at a partial region of intrinsic film result into better electrostatic control that regulates the read mechanism based on Band-to-Band Tunneling (BTBT), while the other gate (G2), positioned adjacent to the first front gate is responsible for charge storage and sustenance. The proposed architecture results into enhanced SM of ~1...
August 23, 2017: Nanotechnology
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