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https://www.readbyqxmd.com/read/29331901/an-ultrasensitive-detection-of-mirna-155-in-breast-cancer-via-direct-hybridization-assay-using-two-dimensional-molybdenum-disulfide-field-effect-transistor-biosensor
#1
Samira Mansouri Majd, Abdollah Salimi, Foad Ghasemi
MicroRNAs (miRNAs), critical biomarkers of acute and chronic diseases, play key regulatory roles in many biological processes. As a result, robust assay platforms to enable an accurate and efficient detection of low-level miRNAs in complex biological samples are of great significance. In this work, a label-free and direct hybridization assay using molybdenum disulfide (MoS2) field-effect transistor (FET) biosensor has been developed for ultrasensitive detection of miRNA-155 as a breast cancer biomarker in human serum and cell-line samples...
January 6, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29331236/pregnancy-related-complications-and-perinatal-outcomes-resulting-from-transfer-of-cryopreserved-versus-fresh-embryos-in%C3%A2-vitro-fertilization-a-meta-analysis
#2
Tingting Sha, Xunqiang Yin, Wenwei Cheng, Isaac Yaw Massey
OBJECTIVE: To provide an updated comparison of pregnancy-related complications and adverse perinatal outcomes of pregnancies conceived after frozen embryo transfer (FET) versus fresh embryo transfer (fresh ET). DESIGN: Meta-analysis. SETTING: University. PATIENT(S): Pregnancies resulting from FET versus fresh ET. INTERVENTIONS(S): Pubmed, Embase, Cochrane Library, Google Scholar, and Chinese databases, including the China National Knowledge Infrastructure Database, Wanfang, and Chinese Scientific Journals Full-Text Database were searched by two independent reviewers from January 1980 to September 2017...
January 11, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29331235/antim%C3%A3-llerian-hormone-as-a-predictor-of-live-birth-following-assisted-reproduction-an-analysis-of-85-062-fresh-and-thawed-cycles-from-the-society-for-assisted-reproductive-technology-clinic-outcome-reporting-system-database-for-2012-2013
#3
Reshef Tal, David B Seifer, Ethan Wantman, Valerie Baker, Oded Tal
OBJECTIVE: To determine if serum antimüllerian hormone (AMH) is associated with and/or predictive of live birth assisted reproductive technology (ART) outcomes. DESIGN: Retrospective analysis of Society for Assisted Reproductive Technology Clinic Outcome Reporting System database from 2012 to 2013. SETTING: Not applicable. PATIENT(S): A total of 69,336 (81.8%) fresh and 15,458 (18.2%) frozen embryo transfer (FET) cycles with AMH values...
January 11, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29328623/mimicking-biological-synaptic-functionality-with-an-indium-phosphide-synaptic-device-on-silicon-for-scalable-neuromorphic-computing
#4
Debarghya Sarkar, Jun Tao, Wei Wang, Qingfeng Lin, Matthew Yeung, Chenhao Ren, Rehan Kapadia
Neuromorphic or "brain-like" computation is a leading candidate for efficient, fault-tolerant processing of large-scale data, as well as real-time sensing and transduction of complex multivariate systems and networks such as self-driving vehicles or Internet of Things applications. In biology, the synapse serves as an active memory unit in the neural system, and is the component responsible for learning and memory. Electronically emulating this element via a compact, scalable technology which can be integrated in a 3-D architecture is critical for future implementations of neuromorphic processors...
January 12, 2018: ACS Nano
https://www.readbyqxmd.com/read/29327111/the-role-of-the-endometrial-receptivity-array-era-in-patients-who-have-failed-euploid-embryo-transfers
#5
J Tan, A Kan, J Hitkari, B Taylor, N Tallon, G Warraich, A Yuzpe, G Nakhuda
PURPOSE: Endometrial receptivity issues represent a potential source of implantation failure. The aim of this study was to document our experience with the endometrial receptivity array (ERA) among patients with a history of euploid blastocyst implantation failure. We investigated whether the contribution of the endometrial factor could be identified with the ERA test and if actionable results can lead to improved outcomes. METHODS: A retrospective review was performed for 88 patients who underwent ERA testing between 2014 and 2017...
January 11, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29324436/field-effect-transistors-and-phototransistors-based-upon-p-type-solution-processed-pbs-nanowires
#6
Paul Giraud, Bo Hou, Sangyeon Pak, Jung Inn Sohn, Stephen Morris, SeungNam Cha, Jong Min Kim
We demonstrate the fabrication of solution processed highly crystalline p-type PbS nanowires via the oriented attachment of nanoparticles. The analysis of single nanowire field effect transistor (FET) devices revealed a hole conduction behaviour with average mobilities greater than 30 cm2 V-1 s-1, which is an order of magnitude higher than that reported to date for p-type PbS colloidal nanowires. We have investigated the response of the FETs to near-infrared light excitation and show herein that the nanowires exhibited gate-dependent photo-conductivities, enabling us to tune the device performances...
January 11, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29323476/localized-electrothermal-annealing-with-nano-watt-power-for-a-silicon-nanowire-field-effect-transistor
#7
Jun-Young Park, Byung-Hyun Lee, Geon-Beom Lee, Hagyoul Bae, Yang-Kyu Choi
This work investigates localized electrothermal annealing (ETA) with extremely low power consumption. The proposed method utilizes, for the first time, tunneling current-induced Joule heat in a p-i-n diode, comprised of p-type, intrinsic, and n-type semiconductors. The consumed power used for dopant control is the lowest value ever reported. A metal-oxide-semiconductor field-effect transistor (MOSFET) composed of a p-i-n silicon nanowire, which is a sub-structure of a tunneling FET (TFET), was fabricated and utilized as a test platform to examine the annealing behaviors...
January 11, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29322780/signal-and-noise-in-fet-nanopore-devices
#8
William M Parkin, Marija Drndic
The combination of a nanopore with a local field-effect transistor (FET-nanopore), like a nanoribbon, nanotube, or nanowire, in order to sense single molecules translocating through the pore is promising for DNA sequencing at megahertz bandwidths. Previously, it was experimentally determined that the detection mechanism was due to local potential fluctuations that arise when an analyte enters a nanopore and constricts ion flow through it, rather than the theoretically proposed mechanism of direct charge coupling between the DNA and nanowire...
January 11, 2018: ACS Sensors
https://www.readbyqxmd.com/read/29318882/charge-transfer-induced-p-type-channel-in-mos2-flake-field-effect-transistor
#9
Sung-Wook Min, Minho Yoon, Sung Jin Yang, Kyeong Rok Ko, Seongil Im
Two-dimensional (2D) transition-metal dichalcogenide semiconductor (TMD), MoS2 has received extensive attention for decades due to their outstanding electrical and mechanical properties for next generation devices. One weakness of MoS2, however, is that it only shows n-type conduction revealing its limitations for homogeneous PN diodes and complementary inverters. Here, we introduce a charge-transfer method to modify the conduction property of MoS2 from n- to p-type. We initially deposited n-type InGaZnO (IGZO) film on top of MoS2 flake, so that electron charges might be transferred from MoS2 to IGZO during air ambient annealing...
January 10, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29318679/magnetic-induced-piezopotential-gated-mos2-field-effect-transistor-at-room-temperature
#10
Yudong Liu, Junmeng Guo, Aifang Yu, Yang Zhang, Jinzong Kou, Ke Zhang, Rongmei Wen, Yan Zhang, Junyi Zhai, Zhong Lin Wang
Utilizing magnetic field directly modulating/turning the charge carrier transport behavior of field-effect transistor (FET) at ambient conditions is an enormous challenge in the field of micro-nanoelectronics. Here, a new type of magnetic-induced-piezopotential gated field-effect-transistor (MIPG-FET) base on laminate composites is proposed, which consists of Terfenol-D, a ferroelectric single crystal (PMNPT), and MoS2 flake. When applying an external magnetic field to the MIPG-FET, the piezopotential of PMNPT triggered by magnetostriction of the Terfenol-D can serve as the gate voltage to effectively modulate/control the carrier transport process and the corresponding drain current at room temperature...
January 10, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29315845/deformable-organic-nanowire-field-effect-transistors
#11
Yeongjun Lee, Jin Young Oh, Taeho Roy Kim, Xiaodan Gu, Yeongin Kim, Ging-Ji Nathan Wang, Hung-Chin Wu, Raphael Pfattner, John W F To, Toru Katsumata, Donghee Son, Jiheong Kang, James R Matthews, Weijun Niu, Mingqian He, Robert Sinclair, Yi Cui, Jeffery B-H Tok, Tae-Woo Lee, Zhenan Bao
Deformable electronic devices that are impervious to mechanical influence when mounted on surfaces of dynamically changing soft matters have great potential for next-generation implantable bioelectronic devices. Here, deformable field-effect transistors (FETs) composed of single organic nanowires (NWs) as the semiconductor are presented. The NWs are composed of fused thiophene diketopyrrolopyrrole based polymer semiconductor and high-molecular-weight polyethylene oxide as both the molecular binder and deformability enhancer...
January 8, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29313520/the-ambipolar-evolution-of-high-performance-wse2-transistor-assisted-by-ferroelectric-polymer
#12
Dan Li, Xudong Wang, Yan Chen, Sixin Zhu, Fan Gong, Guangjian Wu, Caimin Meng, Lan Liu, Lin Wang, Tie Lin, Shuo Sun, Hong Shen, Xingjun Wang, Wei-Da Hu, Jianlu Wang, Jinglan Sun, Xiangjian Meng, Junhao Chu
In recent years, the electrical characteristics of WSe2 field effect transistors (FETs) have been widely investigated with various dielectrics. Among them, being able to perfectly tune the polarity of WSe2 is a meaningful and promising work. In this work, we systematically study the electrical properties of bilayer WSe2 FETs modulated by ferroelectric polymer poly(vinylidenefluoride-co-trifluoroethylene) (P(VDF-TrFE)). Compared to traditional gate dielectric SiO2, the P(VDF-TrFE) not only can tune both electron and hole concentrations to the same high level, but also improve the hole mobility of bilayer WSe2 to 265...
January 9, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29303866/pet-and-ictal-spect-can-be-helpful-for-localizing-epileptic-foci
#13
Tim J von Oertzen
PURPOSE OF REVIEW: Functional neuroimaging with PET and SPECT is a commonly used tool in presurgical evaluation. The following article reviews the literature of PET and SPECT in presurgical assessment of epilepsies published in the last year. RECENT FINDINGS: FDG-PET adds concomitant information in temporal and extratemporal lobe epilepsy in adults and children. The pattern of hypometabolism in FDG-PET is a good additional predictor or seizure outcome in TLE with mesial temporal sclerosis or negative MRI...
January 4, 2018: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29303553/scalable-preparation-of-high-density-semiconducting-carbon-nanotube-arrays-for-high-performance-field-effect-transistors
#14
Jia Si, Donglai Zhong, Haitao Xu, Meng-Meng Xiao, Chenxi Yu, Zhiyong Zhang, Lianmao Peng
Although chemical vapor deposition (CVD)-grown carbon nanotube (CNT) arrays are considered ideal materials for constructing high-performance field-effect transistors (FETs) and integrated circuits (ICs), a significant gap remains between the required and achieved densities and purities of CNT arrays. Here, we develop a directional shrinking transfer method to realize up to 10-fold density amplification of CNT array films without introducing detectable damage or defects. In addition, the method improves the film uniformity while retaining the perfect alignment and high carrier mobility of 1,600 cm2V-1s-1 of CVD-grown CNT arrays...
January 5, 2018: ACS Nano
https://www.readbyqxmd.com/read/29300975/new-application-of-dydrogesterone-as-a-part-of-a-progestin-primed-ovarian-stimulation-protocol-for-ivf-a-randomized-controlled-trial-including-516-first-ivf-icsi-cycles
#15
Sha Yu, Hui Long, Hannah Ya-Ning Chang, Yali Liu, Hongyuan Gao, Jing Zhu, Xinxin Quan, Qifeng Lyu, Yanping Kuang, Ai Ai
STUDY QUESTION: Can dydrogesterone (DYG) be used as an alternative progestin in a progesterone primed ovarian stimulation (PPOS) protocol? SUMMARY ANSWER: DYG can be used as an appropriate alternative progestin in a PPOS protocol. WHAT IS KNOWN ALREADY: PPOS is a new ovarian stimulation regimen based on a freeze-all strategy that uses progestin as an alternative to a GnRH analog for suppressing a premature LH surge during the follicular phase...
December 29, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29297113/frozen-blastocyst-transfer-outcomes-in-immediate-versus-delayed-subsequent-cycles-following-gnrh-agonist-or-hcg-triggers
#16
Leah Kaye, Audrey Marsidi, Puja Rai, Jeffrey Thorne, John Nulsen, Lawrence Engmann, Claudio Benadiva
PURPOSE: The aim of this study is to analyze clinical pregnancy rates (CPR) and ongoing pregnancy rates (OPR) for frozen embryo transfers (FET) performed with blastocysts in the cycle immediately after GnRH agonist (GnRHa) versus human chorionic gonadotropin (hCG) triggers, with outcomes of delayed FET for comparison. METHODS: Retrospective cohort study at a university-affiliated in vitro fertilization (IVF) clinic, including patients undergoing IVF between 2013-16 with a blastocyst FET performed within two menstrual cycles of a previous stimulation cycle and vaginal oocyte retrieval (VOR)...
January 3, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29296994/tunable-schottky-contacts-in-mse2-nbse2-m-mo-and-w-heterostructures-and-promising-application-potential-in-field-effect-transistors
#17
Xingshuai Lv, Wei Wei, Pei Zhao, Jinjin Li, Baibiao Huang, Ying Dai
The performance of electronic and optoelectronic devices based on two-dimensional (2D) materials could be significantly affected by the electrical contacts. In search of low-resistance contacts with transition-metal dichalcogenides (TMDs), we combine density functional calculations with quantum transport simulations to investigate the structural and electronic properties of the van der Waals (vdW) heterostructures MSe2/NbSe2 (M = Mo and W). The formation of a p-type Schottky contact at the MSe2/NbSe2 interface with small Schottky barriers (0...
January 3, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29291410/effect-of-frozen-thawed-embryo-transfer-on-birthweight-macrosomia-and-low-birthweight-rates-in-us-singleton-infants
#18
Julia F Litzky, Sheree L Boulet, Navid Esfandiari, Yujia Zhang, Dmitry M Kissin, Regan N Theiler, Carmen J Marsit
BACKGROUND: Singleton infants conceived using assisted reproductive technology have lower average birthweights than naturally-conceived infants and are more likely to be born low birthweight (<2500 grams). Lower birthweights are associated with increased infant and child mortality and poor adult health outcomes, including cardiovascular disease, hypertension, and diabetes. Data from registry and single center studies suggest that frozen/thawed embryo transfer may be associated with larger birthweights...
December 29, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29289320/ultrasensitive-flexible-fet-type-aptasensor-for-ca-125-cancer-marker-detection-based-on-carboxylated-multiwalled-carbon-nanotubes-immobilized-onto-reduced-graphene-oxide-film
#19
Samira Mansouri Majd, Abdollah Salimi
The development of a novel flexible and ultrasensitive aptasensor based on carboxylated multiwalled carbon nanotubes (MWCNTs)/ reduced graphene oxide-based field effect transistor (FET) has been reported for label-free detection of the ovarian cancer antigen (CA125). The fabricated sensor has a straightforward design based on the noncovalent attachment of MWCNTs/aptamer conjugated onto few layers reduced graphene oxide nanosheets and its integration with poly-methyl methacrylate (PMMA) as a suitable platform for designing flexible field-effect transistors...
February 13, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29288552/effects-of-intrauterine-perfusion-of-human-chorionic-gonadotropin-in-women-with-different-implantation-failure-numbers
#20
Pinxiu Huang, Lihong Wei, Xinlin Li, Aiping Qin
PROBLEM: The aim of this research was to investigate the effects of the intrauterine perfusion of hCG before a frozen-thawed embryo transfer (FET) in women with different implantation failure numbers. METHOD OF STUDY: This was a retrospective analysis of patients undergoing FET who received an intrauterine injection hCG 1000 IU before embryo transfer. The groups included women with their first implantation failure (A group, n = 26), second implantation failure (B group, n = 122), and three or more failures (C group, n = 77)...
December 30, 2017: American Journal of Reproductive Immunology: AJRI
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