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Masayuki Suda, Hiroshi M Yamamoto
Stimulated by the discovery of high-temperature superconductivity in 1986, band-filling control of strongly correlated electron systems has been a persistent challenge over the past three decades in condensed matter science. In particular, recent efforts have been focused on electrostatic carrier doping of these materials, utilising field-effect transistor (FET) structures to find novel superconductivity. Our group found the first field-induced superconductivity in an organic-based material in 2013 and has been developing various types of superconducting organic FETs...
November 17, 2017: Physical Chemistry Chemical Physics: PCCP
Matti Kaisti, Anssi Kerko, Eero Aarikka, Petri Saviranta, Zhanna Boeva, Tero Soukka, Ari Lehmusvuori
We demonstrate an electrochemical sensor for detection of unlabeled single-stranded DNA using peptide nucleic acid (PNA) probes coupled to the field-effect transistor (FET) gate. The label-free detection relies on the intrinsic charge of the DNA backbone. Similar detection schemes have mainly concentrated on sensitivity improvement with an emphasis on new sensor structures. Our approach focuses on using an extended-gate that separates the FET and the sensing electrode yielding a simple and mass fabricable device...
November 16, 2017: Scientific Reports
So Young Yeo, Sangsik Park, Yeonjin Yi, Do Hwan Kim, Jung Ah Lim
A highly sensitive pressure sensor based on a printed organic transistors with three-dimensionally self-organized organic semiconductor microstructures were demonstrated. A unique organic transistor with semiconductor channels positioned at the highest summit of printed cylindrical microstructures was achieved simply by printing an organic semiconductor and polymer blend on the plastic substrate without the use of additional etching or replication processes. A combination of the printed organic semiconductor microstructure and an elastomeric top-gate dielectric resulted in a highly sensitive OFET pressure sensor with a high pressure sensitivity of 1...
November 15, 2017: ACS Applied Materials & Interfaces
Åsa Magnusson, Karin Källen, Ann Thurin-Kjellberg, Christina Bergh
STUDY QUESTION: What is the relationship between the number of oocytes collected in fresh IVF treatments and the likelihood of cumulative delivery rate (fresh and frozen) per oocyte aspiration, severe ovarian hyperstimulation syndrome (OHSS) and thromboembolic events? SUMMARY ANSWER: Cumulative delivery rate per aspiration increases up to 20 oocytes retrieved and then evens out while the incidence of severe OHSS increases more rapidly from around 18 oocytes and thromboembolic events, although rare, occurs in particular if 15 or more oocytes are retrieved...
November 10, 2017: Human Reproduction
Xiaoli Zhao, Bing Zhang, Qingxin Tang, Xueyan Ding, Shuya Wang, Yuying Zhou, Yanhong Tong, Yichun Liu
Conformal transistor array based on solution-processed organic crystals, which can provide sensory and scanning features for monitoring, biofeedback, and tracking of physiological function, presents one of the most promising technologies for future large-scale low-cost wearable and implantable electronics. However, it is still a huge challenge for the integration of solution-processed organic crystals into conformal FETs owing to a generally existing swelling phenomenon of the elastic materials and the lack of the corresponding device fabrication technology...
November 13, 2017: Scientific Reports
Yao-Fang Liu, Fang Wang, Gui-Ying Huang, Xi-Guang Mao
OBJECTIVE: To analyze the relationship between outcomes of hormone replacement therapy-frozen embryo transfer (HRT-FET) and serum estradiol and progesterone levels on the day of endometrial transformation and before transplantation. METHODS: Clinical datas of patients who underwent 426 cycles of FET were retrospectively analyzed and were divided into groups according to estradiol and progesterone levels. Differences in embryo implantation rate and clinical pregnancy rate were compared, and relationship between estradiol levels and outcome of transplantation was analyzed...
November 10, 2017: Minerva Endocrinologica
B Ibarlucea, T Rim, C K Baek, J A G M de Visser, L Baraban, G Cuniberti
Miniaturized and cost-efficient methods aiming at high throughput analysis of microbes are of great importance for the surveillance and control of infectious diseases and the related issue of antimicrobial resistance. Here we demonstrate a miniature nanosensor based on a honeycomb-patterned silicon nanowire field effect transistor (FET) capable of detection of bacterial growth and antibiotic response in microbiologically relevant nutrient media. We determine the growth kinetics and metabolic state of Escherichia coli cells in undiluted media via the quantification of changes in the source-drain current caused by varying pH values...
November 9, 2017: Lab on a Chip
Haoyue Yang, Masatoshi Honda, Akiko Saito, Taira Kajisa, Yuhki Yanase, Toshiya Sakata
In this study, we report the label-free and reliable detection of allergic response using a cell-coupled gate field-effect transistor (cell-based FET). Rat basophilic leukemia (RBL-2H3) cells were cultured as a signal transduction interface to induce allergic reaction on the gate oxide surface of the FET, because IgE antibodies, which bind to Fcε receptors at the RBL-2H3 cell membrane, are specifically cross-linked by allergens, resulting in the allergic response of RBL-2H3 cells. In fact, the surface potential at the FET gate decreased owing to secretions such as histamine from the IgE-bound RBL-2H3 cells, which reacted with the allergen...
November 15, 2017: Analytical Chemistry
Yu-Ru Lin, Wan-Ting Tsai, Yung-Chun Wu, Yu-Hsien Lin
This study demonstrated an ultra thin poly-Si junctionless nanosheet field-effect transistor (JL NS-FET) with nickel silicide contact. For the nickel silicide film, two-step annealing and a Ti capping layer were adopted to form an ultra thin uniform nickel silicide film with low sheet resistance (Rs). The JL NS-FET with nickel silicide contact exhibited favorable electrical properties, including a high driving current (>10⁷A), subthreshold slope (186 mV/dec.), and low parasitic resistance. In addition, this study compared the electrical characteristics of JL NS-FETs with and without nickel silicide contact...
November 7, 2017: Materials
Jie Li, Ke Zhou, Jie Liu, Yonggang Zhen, Li Liu, Jidong Zhang, Huanli Dong, Xiaotao Zhang, Lang Jiang, Wenping Hu
Organic semiconductors integrating excellent charge transport with efficient solid emission are very challenging to be attained in the construction of light-emitting transistors and even for realization of electrically pumped organic lasers. Herein, we introduce naphthyl units at 2,6-positions of anthracene to achieve 2,6-di(2-naphthyl)anthracene (dNaAnt), which adopts J-aggregated mode in the solid state as a balanced strategy for excellent charge transporting and efficient solid state emission. Single crystal field-effect transistors show mobility up to 12...
November 14, 2017: Journal of the American Chemical Society
Xiumei Zhang, Haiyan Nan, Shaoqing Xiao, Xi Wan, Zhenhua Ni, Xiaofeng Gu, Kostya Ken Ostrikov
Two-dimensional molybdenum disulfide (MoS2) has recently drawn great attention due to its promising applications in electronics and optoelectronics. Chemical vapor deposition (CVD) is a scalable method to produce large-area MoS2 monolayers, yet it is challenging to achieve shape-uniform, high-quality monolayer MoS2 grains as random, diverse crystallographic orientations and various shapes are produced in the same CVD process. Here we report the growth of high-quality MoS2 monolayers with uniform trianglular shapes dominating (up to 89%) over other shapes on both SiO2/Si and sapphire substrates...
November 7, 2017: ACS Applied Materials & Interfaces
Jan Oliver Dittmar, Clemens Kratochwil, Anne Dittmar, Thomas Welzel, Daniel Habermehl, Stefan Rieken, Frederik L Giesel, Uwe Haberkorn, Jürgen Debus, Stephanie E Combs
BACKGROUND: For irradiation treatment planning of meningiomas the use of PET-scans is well established. The most frequently used tracers are either based on amino acids or the somatostatin receptor ligand DOTATOC. Since up to now no inter-institutionally accepted standard PET-tracer has been defined, the aim of this study was to evaluate the influence of these different types of PET-tracers on the GTV-definition. METHODS: Twenty-one patients suffering from intracranial meningiomas underwent CT, MRI, FET- and DOTATOC-PET...
November 6, 2017: Radiation Oncology
Seung Bae Son, Yonghun Kim, AhRa Kim, Byungjin Cho, Woong-Ki Hong
Atomically thin two-dimensional (2D) van der Waals (vdW) heterostructures are one of the very important research issues for stacked optoelectronic device applications. In this study, using the transferred and stacked NbSe2-WSe2 films as electrodes and a channel, we fabricated the field-effect transistor (FET) devices based on 2D-2D vdW metal-semiconductor heterojunctions (HJs) and systematically studied their ultraviolet (UV) wavelength-dependent electrical and photoresponse properties. Upon the exposure to UV light with a wavelength of 365 nm, the NbSe2-WSe2 vdW HJFET devices exhibited threshold voltage shift toward positive gate bias direction, a current increase, and a nonlinear photocurrent increase upon applying a gate bias due to the contribution of the photogenerated hole current...
November 14, 2017: ACS Applied Materials & Interfaces
I Hatoum, L Bellon, N Swierkowski, M Ouazana, S Bouba, K Fathallah, B Paillusson, M Bailly, F Boitrelle, L Alter, M Bergère, J Selva, R Wainer
PURPOSE: The purpose of this study was to determine the effect of stimulated and artificial endometrial preparation protocols on reproductive outcomes in frozen embryo transfer (FET) cycles. METHODS: We performed a retrospective study of 1926 FET cycles over a 3.5-year period in the Fertility Unit at a University Hospital. Stimulated and artificial protocols were used for endometrial preparation. The embryos for FET were obtained from either in vitro fertilization or intracytoplasmic sperm injection cycles...
November 6, 2017: Journal of Assisted Reproduction and Genetics
Ning Yu, Masahiro Nakajima, Qing Shi, Zhan Yang, Huaping Wang, Lining Sun, Qiang Huang, Toshio Fukuda
A high contact resistance restricts the application of carbon nanotubes (CNTs) in fabrication of field-effect transistors (FETs). Thus, it is important to decrease the contact resistance and investigate the critical influence factors such as the contact length and contact force. This study uses nanomanipulation to characterize both the resistance and the force at a CNT/Au side-contact interface inside a scanning electron microscopy (SEM). Two-terminal CNT manipulation methods, and models for calculating the resistance and force at contact area, are proposed to guide the measurement experiments of a total resistance and a cantilever's elastic deformation...
2017: Scanning
Francesca Pasi, Marco Giovanni Persico, Federica Eleonora Buroni, Carlo Aprile, Marina Hodolic, Franco Corbella, Rosanna Nano, Angelica Facoetti, Lorenzo Lodola
The differential diagnosis between recurrence of gliomas or brain metastases and this phenomenon is important in order to choose the best therapy and predict the prognosis but is still a big problem for physicians. The new emerging MRI, CT, and PET diagnostic modalities still lack sufficient accuracy. Radiolabeled choline and amino acids have been reported to show great tumor specificity. We studied the uptake kinetics of [(18)F]fluoromethyl-choline (FCH) and O-(2-[(18)F]fluoroethyl)-L-tyrosine (FET) by the T98G human glioblastoma cells from 20 to 120 min after irradiation either with photons at 2-10-20 Gy or with carbon ions at 2 Gy (at the National Centre for Oncological Hadrontherapy (CNAO), Pavia, Italy)...
2017: Contrast Media & Molecular Imaging
Min Je Kim, A-Ra Jung, Myeongjae Lee, Dongjin Kim, Suhee Ro, Seon-Mi Jin, Hieu Dinh Nguyen, Jee Hye Yang, Kyung-Koo Lee, Eunji Lee, Moon Sung Kang, Hyunjung Kim, Jong-Ho Choi, BongSoo Kim, Jeong Ho Cho
We report high-performance top-gate bottom-contact flexible field-effect polymer transistors (FETs) fabricated by flow-coating diketopyrrolopyrrole (DPP)-based and naphthalene diimide (NDI)-based polymers (P(DPP2DT-T2), P(DPP2DT-TT), P(DPP2DT-DTT), P(NDI2OD-T2), P(NDI2OD-F2T2), and P(NDI2OD-Se2)) as semiconducting channel materials. All of the polymers displayed good FET characteristics with on/off current ratios exceeding 10(7). The highest hole mobility of 1.51 cm(2)V(-1)s(-1) and the highest electron mobility of 0...
November 1, 2017: ACS Applied Materials & Interfaces
Gwangseok Yang, Soohwan Jang, Fan Ren, Stephen J Pearton, Jihyun Kim
The robust radiation resistance of wide-band gap materials is advantageous for space applications, where the high-energy particle irradiation deteriorates the performance of electronic devices. We report on the effects of proton irradiation of β-Ga2O3 nanobelts, whose energy band gap is ∼4.85 eV at room temperature. Back-gated field-effect transistor (FET) based on exfoliated quasi-two-dimensional β-Ga2O3 nanobelts were exposed to a 10 MeV proton beam. The proton-dose- and time-dependent characteristics of the radiation-damaged FETs were systematically analyzed...
November 7, 2017: ACS Applied Materials & Interfaces
Markus Hutterer, Elisabeth Bumes, Markus J Riemenschneider, Jirka Grosse, Dirk Hellwig, Norbert Galldiks, Karl-Josef Langen, Peter Hau
We report the case of a 40-year-old woman with a progressive right-sided hemiparesis. Standard MRI revealed a contrast-enhancing brain lesion within the left basal ganglia. Ffluoroethyl-L-tyrosine (F-FET) PET showed a distinct tracer uptake (lesion-to-brain ratio [LBR]: LBRmax = 2.03, LBRmean = 1.68) with a significant larger metabolic lesion volume than contrast-enhancement in MRI, indicating cerebral glioma. Surprisingly, histopathologic analysis demonstrated central nervous system toxoplasmosis with pronounced inflammatory reaction (reactive astrogliosis, microglia activation, macrophage, and T-lymphocyte infiltration), which was associated with strong LAT1/LAT2/CD98 expression...
October 26, 2017: Clinical Nuclear Medicine
Hong Kyw Choi, Jaesung Park, Nojoon Myoung, Ho-Jong Kim, Jin Sik Choi, Young Kyu Choi, Chi-Young Hwang, Jin Tae Kim, Serin Park, Yoonsik Yi, Soo Kyung Chang, Hee Chul Park, Chanyong Hwang, Choon-Gi Choi, Young-Jun Yu
van der Waals (vdW) heterostructures with two-dimensional (2D) crystals such as graphene, hexagonal boron nitride (hBN) and transition metal dichalcogenides (TMDCs) allow us to demonstrate atomically thin field-effect transistors (FETs), photodetectors (PDs) and photovoltaic devices capable of higher performance and greater stability levels than conventional devices. Although there have been studies of gas molecule sensing with 2D crystal channels, vdW heterostructures based on 2D crystals have not been employed thus far...
October 27, 2017: Nanoscale
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