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https://www.readbyqxmd.com/read/29234981/sarcopenia-after-induction-therapy-in-childhood-acute-lymphoblastic-leukemia-its-clinical-significance
#1
Daisuke Suzuki, Ryoji Kobayashi, Hirozumi Sano, Daiki Hori, Kunihiko Kobayashi
Muscle weakness is one of the most serious problems during chemotherapy for childhood hematological malignancies. It may be caused by long-term hospitalization, unfavorable physical conditions, and restricted activities. Although the concept of sarcopenia is becoming widely recognized, especially in geriatric medicine, there have been few reports about sarcopenia in pediatric patients with hematological malignancies. A total of 47 consecutive first-onset acute lymphoblastic leukemia (ALL) patients who underwent induction therapy between January 2011 and September 2016 were investigated...
December 12, 2017: International Journal of Hematology
https://www.readbyqxmd.com/read/29230961/health-and-social-factors-associated-with-a-delayed-discharge-amongst-inpatients-in-acute-geriatric-wards-a-retrospective-observational-study
#2
George Moore, Peter Hartley, Roman Romero-Ortuno
AIM: In the English National Health Service there is an increasing interest in understanding the factors associated with delayed discharges in older hospitalized adults. The present study sought to analyze whether clinical frailty was a significant and independent risk factor for having a delayed discharge when the data were controlled for potential health and social confounders. METHODS: This was a retrospective observational study in an English National Health Service teaching hospital...
December 12, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29230125/older-patients-with-acute-myeloid-leukemia-treatment-challenges-and-future-directions
#3
REVIEW
Laura Finn, Andrew Dalovisio, James Foran
Background: Even though acute myeloid leukemia (AML) occurs most commonly in adults ≥60 years, the treatment of AML in older patients remains a significant challenge. Methods: We reviewed the current literature regarding patient assessment tools, treatment options, and current therapies in clinical trial for patients with AML who are ≥60 years. Results: Our approach to the older patient with AML is evolving with better understanding of the unique disease epidemiology in this population and the development of tools to assess individual patient functional status, including grading systems for comorbidities, geriatric assessment tools, and measurements of frailty...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29219828/improving-care-for-older-patients-in-the-acute-setting-a-qualitative-study-with-healthcare-providers
#4
C Brouwers, H Merten, M Willems, D J Habraken, F W Bloemers, T H Biesheuvel, L S van Galen, P W B Nanayakkara, C Wagner
BACKGROUND: The proportion of older people needing acute care is rapidly growing, thereby posing an increased burden on the acute care chain. The aim of this study is to gain more insight into the obstacles and potential improvement opportunities of the acute care process for older patients arriving at the hospital. METHODS: Semi-structured interviews were conducted to determine the experiences of 18 different primary (i.e. general practitioner, community nurse) and secondary healthcare professionals (i...
October 2017: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/29219810/optimising-the-isar-hp-to-screen-efficiently-for-functional-decline-in-older-patients
#5
J de Gelder, E Haenen, J A Lucke, H G Klop, L C Blomaard, R A J Smit, K Mesri, B de Groot, A J Fogteloo, S Anten, G J Blauw, S P Mooijaart
INTRODUCTION: The Identification of Seniors At Risk-Hospitalised Patients (ISAR-HP) has recently been included in guidelines as a frailty indicator to identify patients for comprehensive geriatric assessment. Previous studies showed that the conventional cut-off score incorrectly classifies a high percentage of patients as high risk. We aimed to optimise the predictive value of ISAR-HP by using different cut-offs in older acutely hospitalised patients. METHODS: A prospective follow-up study was performed in two Dutch hospitals...
November 2017: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/29207725/rapid-and-accurate-diagnosis-of-acute-pyogenic-meningitis-due-to-streptococcus-pneumoniae-haemophilus-influenzae-type-b-and-neisseria-meningitidis-using-a-multiplex-pcr-assay
#6
Rajeev Seth, Peela Sree Ramchandra Murthy, Sujatha Sistla, Mahadevan Subramanian, Kadhiravan Tamilarasu
Introduction: Acute bacterial meningitis is one of the major causes of morbidity and mortality in children and geriatric population, especially in developing countries. Methods of identification are standard culture and other phenotypic tests in many resource poor settings. Aim: To use molecular methods for the improvement of aetiological diagnosis of acute pyogenic meningitis in patients. Materials and Methods: CSF samples of 125 patients were included for the study...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29206906/what-is-comprehensive-geriatric-assessment-cga-an-umbrella-review
#7
S G Parker, P McCue, K Phelps, A McCleod, S Arora, K Nockels, S Kennedy, H Roberts, S Conroy
Background: comprehensive geriatric assessment (CGA) is now the accepted gold standard for caring for frail older people in hospital. However, there is uncertainty about identifying and targeting suitable recipients and which patients benefit the most. Objectives: our objectives were to describe the key elements, principal measures of outcome and the characteristics of the main beneficiaries of inpatient CGA. Methods: we used the Joanna Briggs Institute umbrella review method...
December 1, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29205846/use-and-clinical-efficacy-of-standard-and-health-information-technology-fall-risk-assessment-tools
#8
Ruth C Teh, Anne Wilson, Damith Ranasinghe, Renuka Visvanathan
OBJECTIVE: To evaluate the health information technology (HIT) compared to Fall Risk for Older Persons (FROP) tool in fall risk screening. METHODS: A HIT tool trial was conducted on the geriatric evaluation and management (GEM, n = 111) and acute medical units (AMU, n = 424). RESULTS: Health information technology and FROP scores were higher on GEM versus AMU, with no differences between people who fell and people who did not fall. Both score completion rates were similar, and their values correlated marginally (Spearman's correlation coefficient 0...
December 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/29196372/acute-geriatrics-at-the-front-door
#9
Mike P Houghton
No abstract text is available yet for this article.
December 2017: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29193694/association-between-diabetes-and-mortality-in-elderly-patients-admitted-for-a-first-episode-of-acute-heart-failure
#10
Francesc Formiga, David Chivite, Abelardo Montero, Irene Petit, Rafael Moreno-González, Jonathan Franco, Xavier Corbella
AIM: To examine whether the presence of a prior diagnosis of diabetes mellitus (DM) influences mortality risk in elderly patients experiencing a first episode of heart failure (HF) hospitalization. METHODS: A total of 677 consecutive patients aged ≥75 years admitted for a first episode of acute decompensated heart failure were evaluated according to the presence or not of DM, and in-hospital and 1-year mortality rates were evaluated. RESULTS: A total of 240 patients (35...
November 28, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29180856/effects-of-comprehensive-geriatric-assessment-on-physical-fitness-in-an-acute-medical-setting-for-frail-elderly-patients
#11
Kristina Åhlund, Maria Bäck, Birgitta Öberg, Niklas Ekerstad
Introduction: Frail elderly people often use emergency care. During hospitalization, physical decline is common, implying an increased risk of adverse health outcomes. Comprehensive Geriatric Assessment (CGA) has been shown to be beneficial for these patients in hospital care. However, there is very limited evidence about the effects on physical fitness. The aim was to compare effects on physical fitness in the acute care of frail elderly patients at a CGA unit versus conventional care, 3 months after discharge...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29179708/comparing-doctors-legal-compliance-across-three-australian-states-for-decisions-whether-to-withhold-or-withdraw-life-sustaining-medical-treatment-does-different-law-lead-to-different-decisions
#12
Ben P White, Lindy Willmott, Colleen Cartwright, Malcolm Parker, Gail Williams, Juliet Davis
BACKGROUND: Law purports to regulate end-of-life care but its role in decision-making by doctors is not clear. This paper, which is part of a three-year study into the role of law in medical practice at the end of life, investigates whether law affects doctors' decision-making. In particular, it considers whether the fact that the law differs across Australia's three largest states - New South Wales (NSW), Victoria and Queensland - leads to doctors making different decisions about withholding and withdrawing life-sustaining treatment from adults who lack capacity...
November 28, 2017: BMC Palliative Care
https://www.readbyqxmd.com/read/29177470/impaired-cognition-is-associated-with-adverse-outcome-in-older-patients-in-the-emergency-department-the-acutely-presenting-older-patients-apop-study
#13
J A Lucke, J de Gelder, C Heringhaus, R C van der Mast, A J Fogteloo, S Anten, G J Blauw, B de Groot, S P Mooijaart
Objective: to investigate whether cognitive impairment, measured early after Emergency Department (ED) arrival and irrespective of its cause, is independently associated with functional decline or mortality after 3 and 12 months in older ED patients. Design and setting: a prospective multi-centre cohort study in all Acutely Presenting Older Patients visiting the Emergency Department (APOP study) of three hospitals in the Netherlands. Participants: 2,130 patients, ≥70 years...
November 21, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29171127/how-many-geriatricians-should-at-minimum-be-staffing-health-regions-in-australia
#14
Toby Commerford
In any particular region, determining an adequate, quantifiable geriatrician full-time equivalent required to run geriatric medicine services comprehensively - that is spanning both inpatient and outpatient settings - remains an imperfect science. Whilst workforce planning may be addressed through 'demand versus supply' simulations, 'specialist-to-patient ratios' (SPRs) may be a useful additional workforce metric. There has never been a yardstick SPR, which 'defines' a satisfactory level of geriatrician manpower in any particular Australian hospital catchment...
November 24, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/29170333/36%C3%A2-frailty-flying-squad-an-emergency-department-focussed-acute-care-of-the-elderly-service-dr-genevieve-robson-royal-united-hospital-nhs-foundation-trust
#15
Samantha Ballham, Scott Buxton, Rosa Camacho, Adrianna Sinclair, Chris Dyer, Nicola Jakeman
INTRODUCTION: The over 75 s make up 20% of our ED attendances. The greatest increase has been in the over 85 s. This very elderly cohort are more likely to be frail and are 10X more likely to require admission than 20-40 year olds and once in hospital have longer stays. There is evidence that multidisciplinary care and early Comprehensive Geriatric Assessment (CGA) improves outcomes for older patients, reducing readmissions, long term care, greater satisfaction and lower costs. The aim of this project was to improve the acute care provided to our older patients at the Front Door of the hospital...
December 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29169901/-transfusion-practices-in-elderly-patients-a-descriptive-study-about-241%C3%A2-patients-at-the-university-hospital-of-brest
#16
C Le Niger, N Magne Tagne, A Gentric
Red blood cell transfusion is commonly required for elderly patients with little specific guidelines for this population. We wished to study the transfusion practices for patients aged≥75 years transfused with red blood cells in all units of our institution. The aim of this work is to describe this population of patients and to compare the transfusion practices to the HAS and ANSM guidelines published in 2014. METHODS: An observational study was performed including patients≥75 years, transfused with red blood cells between 27th January to 27th March 2014...
November 20, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/29168884/transformation-of-a-geriatric-department-in-china
#17
Birong Dong, Jirong Yue, Li Cao, Ming Yang, Ning Ge, Hao Qiukui, Lujia He, Ying Wang, Joseph H Flaherty
China has the world's largest elderly population, and the oldest-old population, with a current disability rate greater than 50%, will triple in the next 35 years. The field of geriatrics is young, because almost all geriatric departments were established after 2000, and so faces many challenges. Management of diseases and hospital care is the focus. Senior physicians were trained in other subspecialties, such as pulmonary or cardiology, and junior physicians entered geriatrics departments as masters or doctorate students after medical school...
November 23, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29164125/malnutrition-upon-hospital-admission-in-geriatric-patients-why-assess-it
#18
Paolo Orlandoni, Claudia Venturini, Nikolina Jukic Peladic, Annarita Costantini, Mirko Di Rosa, Claudia Cola, Natascia Giorgini, Redenta Basile, Donata Fagnani, Debora Sparvoli, Serenella David
Objective: To assess the prevalence of malnutrition according to the new ESPEN definition in a population of geriatric hospital patients and to determine how malnutrition affects the length of hospital stay (LOS) and hospital mortality. Design: A retrospective analysis of data gathered during nutritional screening surveys carried out three consecutive years, from 2012 to 2014, in an Italian geriatric research hospital (INRCA, Ancona) was performed. On the day of the study, demographic data, data on clinical conditions and the nutritional status of newly admitted patients were collected...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29154053/acupuncture-and-kinesio-taping-for-the-acute-management-of-bell-s-palsy-a-case-report
#19
Derya Özmen Alptekin
BACKGROUND: Bell's palsy is an idiopathic, acute peripheral palsy of the facial nerve that supplies the muscles of facial expression. Despite an expected 70% full recovery rate, up to 30% of patients are left with potentially disfiguring facial weakness, involuntary movements, or persistent lacrimation. The most frequently used treatment options are corticosteroids and antiviral drugs. However, accompanying clinical conditions, such as uncontrolled diabetes, hypertension, gastrointestinal disturbances, polypharmacy of geriatric patients, and significant sequelae ratios, indicate the need for safe and effective complementary therapies that would enhance the success of the conventional interventions...
December 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29153753/an-easy-assessment-of-frailty-at-baseline-independently-predicts-prognosis-in-very-elderly-patients-with-acute-coronary-syndromes
#20
Oriol Alegre, Francesc Formiga, Ramón López-Palop, Francisco Marín, María T Vidán, Manuel Martínez-Sellés, Antoni Carol, Alessandro Sionis, Pablo Díez-Villanueva, Jaime Aboal, Anna Palau-Vendrel, Héctor Bueno, Angel Perez Rivera, Juan Sanchís, Emad Abu-Assi, Miguel Corbí, Juan C Castillo, Jordi Bañeras, Violeta González-Salvado, Àngel Cequier, Albert Ariza-Solé
BACKGROUND: Information about the impact of frailty in patients with acute coronary syndromes (ACS) is scarce. No study has assessed the prognostic impact of frailty as measured by the FRAIL scale in very elderly patients with ACS. METHODS: The prospective multicenter LONGEVO-SCA registry included unselected patients with ACS aged 80 years or older. A comprehensive geriatric assessment was performed during hospitalization, including frailty assessment by the FRAIL scale...
November 16, 2017: Journal of the American Medical Directors Association
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