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https://www.readbyqxmd.com/read/29027300/pattern-of-in-hospital-changes-in-drug-use-in-the-older-people-from-2010-to-2016
#1
C Franchi, I Ardoino, A Nobili, L Pasina, P M Mannucci, A Maregoni, F Perticone
PURPOSE: To assess the pattern of in-hospital changes in drug use in older patients from 2010 to 2016. METHODS: People aged 65 years or more acutely hospitalized in those internal medicine and geriatric wards that did continuously participate to the REgistro POliterapie Società Italiana di Medicina Interna register from 2010 to 2016 were selected. Drugs use were categorized as 0 to 1 drug (very low drug use), 2 to 4 drugs (low drug use), 5 to 9 drugs (polypharmacy), and 10 or more drugs (excessive polypharmacy)...
October 13, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29022113/a-significant-association-of-malnutrition-with-dysphagia-in-acute-patients
#2
Tsukasa Saito, Keisuke Hayashi, Hajime Nakazawa, Fumika Yagihashi, Leo O Oikawa, Tetsuo Ota
Dysphagia and malnutrition seem to be associated, but little research in detail has been reported. We aimed to clarify the association between dysphagia and malnutrition by adopting accurate diagnosis and mathematical evaluation of dysphagia using videofluorography and nutritional assessment calculated by a well-established nutritional risk index. We conducted a retrospective analysis of 165 enrolled patients who were admitted to our hospital for acute diseases and underwent videofluorography on suspicion of dysphagia in the year 2016...
October 11, 2017: Dysphagia
https://www.readbyqxmd.com/read/28994446/colonization-of-residents-and-staff-of-an-italian-long-term-care-facility-and-an-adjacent-acute-care-hospital-geriatric-unit-by-multidrug-resistant-bacteria
#3
Albert March, Richard Aschbacher, Ferisa Sleghel, Gertrud Soelva, Malgorzata Kaczor, Roberta Migliavacca, Aurora Piazza, Vittoria Mattioni Marchetti, Laura Pagani, Katia Scalzo, Valentina Pasquetto, Elisabetta Pagani
In 2016, we undertook a point prevalence screening study for Enterobacteriaceae with extended-spectrum β-lactamases (ESBLs), high-level AmpC cephalosporinases and carbapenemases, and also methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococci (VRE) in a long-term care facility (LTCF) and the associated acute care hospital geriatric unit in Bolzano, Northern Italy. Urine samples and rectal, inguinal, oropharyngeal and nasal swabs were plated on selective agars. Demographic data were collected...
October 10, 2017: New Microbiologica
https://www.readbyqxmd.com/read/28992984/avoidable-hospitalizations-due-to-adverse-drug-reactions-in-an-acute-geriatric-unit-analysis-of-3-292-patients
#4
Mateu Cabré, Lorena Elias, Mireia Garcia, Elisabet Palomera, Mateu Serra-Prat
OBJECTIVE: To determine prevalence of admissions due to an adverse drug reaction (ADR) and determine whether or not admission was avoidable, and what drugs and risk factors were implicated. DESIGN: Cross-sectional observational study. STUDY SAMPLE: All patients hospitalized in an acute geriatric unit during the period January 2001 to December 2010 were studied. MEASUREMENT: To determine whether admissions were due toADR, we used the World Health Organization-Uppsala Monitoring Centre criteria and the Naranjo scale...
October 6, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28979077/developing-an-integrated-treatment-pathway-for-a-post-coronary-artery-bypass-grating-cabg-geriatric-patient-with-comorbid-hypertension-and-type-1-diabetes-mellitus-for-treating-acute-hypoglycemia-and-electrolyte-imbalance
#5
Atta Abbas Naqvi, Amna Shah, Rizwan Ahmad, Niyaz Ahmad
INTRODUCTION: The ailments afflicting the elderly population is a well-defined specialty of medicine. It calls for an immaculately designed health-care plan to treat diseases in geriatrics. For chronic illnesses such as diabetes mellitus (DM), coronary heart disease, and hypertension (HTN), they require proper management throughout the rest of patient's life. An integrated treatment pathway helps in treatment decision-making and improving standards of health care for the patient. CASE PRESENTATION: This case describes an exclusive clinical pharmacist-driven designing of an integrated treatment pathway for a post-coronary artery bypass grafting (CABG) geriatric male patient with DM type I and HTN for the treatment of hypoglycemia and electrolyte imbalance...
July 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28978831/treatment-of-elderly-patients-with-acute-myeloid-leukemia
#6
Tomonori Nakazato
Most patients diagnosed with acute myeloid leukemia (AML) are over the age of 60 years yet optimal treatment strategies for older adults remain unclear. Old age is associated with increased risk of treatment-related toxicity and worse survival compared to younger adults. It is widely recognized that chronological age does not capture the heterogeneous physiological and functional status of older adults. Thus, it is critically important to evaluate both disease-related (adverse cytogenetics, unfavorable gene mutations, secondary AML, etc...
2017: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
https://www.readbyqxmd.com/read/28972243/assessment-of-clinical-practices-for-crushing-medication-in-geriatric-units
#7
M Fodil, D Nghiem, M Colas, S Bourry, A-S Poisson-Salomon, H Rezigue, C Trivalle
OBJECTIVES: To assess the modification of the form of medication and evaluate staff observance of good clinical practices. DESIGN: One-day assessment of clinical practices. SETTING: 17 geriatrics units in the 3 Teaching Hospitals of Paris-Sud (APHP), France. PARTICIPANTS: Elderly in-patients with difficulties swallowing capsules and tablets. MEASUREMENTS: Assessment of target-patient prescriptions and direct observation of nurses' medical rounds...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28964502/international-practice-settings-interventions-and-outcomes-of-nurse-practitioners-in-geriatric-care-a-scoping-review
#8
REVIEW
Krista S Chavez, Andrew A Dwyer, Anne-Sylvie Ramelet
OBJECTIVES: To identify and summarize the common clinical settings, interventions, and outcomes of nurse practitioner care specific to older people. DESIGN: Scoping review of the international published and grey literature. DATA SOURCES: A structured literature search was conducted of CINAHL, EMBASE, MEDLINE, Google Scholar, and Cochrane Collaboration and Joanna Briggs Institute databases. REVIEW METHODS: Following the Arksey and O'Malley framework, randomized controlled and quasi-experimental studies of Masters-prepared nurse practitioners providing care for patients over 65 years were included...
September 18, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28956138/-influence-of-nosocomial-infections-on-activities-of-daily-living-in-acute-geriatric-inpatients
#9
Damaris Marzahn, Wolfgang Pfister, Anja Kwetkat
BACKGROUND: Nursing home residents and older hospitalized patients have a significantly higher risk to suffer from nosocomial infections (NI). It is still an unanswered question whether patients suffering from NI are at greater risk for deterioration of activities of daily living. MATERIAL AND METHODS: In a retrospective observational study, we evaluated the prevalence of NI during hospitalization of acute geriatric inpatients of the geriatric department at Jena University Hospital by patient records...
September 27, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28954714/baseline-functional-status-as-the-strongest-predictor-of-in-hospital-mortality-in-elderly-patients-with-non-valvular-atrial-fibrillation-results-of-the-nonavasc-registry
#10
A Gullón, F Formiga, M Camafort, J M Mostaza, J Díez-Manglano, J M Cepeda, I Novo-Veleiro, A Pose, C Suárez Fernández
OBJECTIVES: Atrial fibrillation (AF) has been associated with higher mortality. We aimed to identify the baseline predictors of in-hospital mortality among elderly patients with non-valvular AF (NVAF) hospitalised for any reason. METHODS: Observational, prospective and multicentre study was carried out on patients with NVAF over the age of 75, who had been admitted for any acute medical condition to Internal Medicine departments in Spain. RESULTS: We evaluated 804 patients with a mean age of 85±5...
September 24, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28947434/discrepancies-in-drug-histories-at-admission-to-gastrointestinal-surgery-internal-medicine-and-geriatric-hospital-wards-in-central-norway-a-cross-sectional-study
#11
Janne Kutschera Sund, Olav Sletvold, Trude Cecilie Mellingsæter, Randi Hukari, Torstein Hole, Per Einar Uggen, Petra Thiemann Vadset, Olav Spigset
OBJECTIVES: To compare discrepancies in drug histories among patients acutely admitted to different hospital wards, classify the discrepancies according to their potential clinical impact and identify appropriate selection criteria for patients that should be subject to a detailed drug history at admission. DESIGN: Cross-sectional study. SETTING: Two gastrointestinal surgery wards and one geriatric ward at St Olav's University Hospital in Trondheim and two general internal medicine wards at Ålesund Hospital in Ålesund, Norway...
September 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28940784/cognitive-impairment-has-no-impact-on-hospital-associated-dysphagia-in-aspiration-pneumonia-patients
#12
Keisuke Maeda, Hidetaka Wakabayashi, Hiroshi Shamoto, Junji Akagi
AIM: Hospital-associated dysphagia, characterized by deconditioning of swallowing as a result of hospitalization, is sometimes observed in patients with aspiration pneumonia (AP). Cognitive impairment is known as a negative factor in dysphagia rehabilitation. The present study aimed to examine the association between cognitive impairment and hospital-associated dysphagia in patients with AP receiving dysphagia rehabilitation. METHODS: A retrospective observational study was carried out in an acute geriatric hospital...
September 21, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28939010/-evaluation-of-the-prescription-of-proton-pump-inhibitors-in-persons-aged-75years-and-older-in-a-geriatric-acute-care-unit
#13
Mélanie Dipanda, Laureline Pioro, Maxime Buttard, Philippe d'Athis, Sanaa Asgassou, Sophie Putot, Martha Deïdda, Caroline Laborde, Alain Putot, Patrick Manckoundia
INTRODUCTION AND OBJECTIVES: Proton pump inhibitors (PPI) are widely prescribed in France and could be responsible for adverse drug reactions especially in elderly persons (EP). In order to reduce the misuse of PPI and the excess cost to the Social Security Agency, the French health authorities (Haute Autorité de santé [HAS]) have published strict guidelines for their prescription. We conducted a study in EP to determine the proportion of PPI prescriptions outside HAS guidelines. METHOD: This was a prospective, single-centre observational study in persons aged≥75 years admitted to a geriatric acute-care unit over a period of 6months...
July 29, 2017: Thérapie
https://www.readbyqxmd.com/read/28931310/the-management-and-treatment-of-acute-leukemias-in-the-elderly-population
#14
Xavier Thomas
Treatment of elderly patients with acute leukemia is challenging. Older age is associated with increased risk of treatment-related toxicity. Currently, no consensus exists regarding optimal therapy in this patient population. Areas covered: The following review is a comprehensive summary of various therapeutic options reported over the past few years in elderly patients with acute leukemia. Expert commentary: While evidences can guide identification of frail older patients, sensitive assessment strategies are required to identify fit and vulnerable patients regardless of chronologic age...
October 3, 2017: Expert Review of Hematology
https://www.readbyqxmd.com/read/28922625/living-and-dying-with-advanced-dementia-a-prospective-cohort-study-of-symptoms-service-use-and-care-at-the-end-of-life
#15
Elizabeth L Sampson, Bridget Candy, Sarah Davis, Anna Buylova Gola, Jane Harrington, Michael King, Nuriye Kupeli, Gerry Leavey, Kirsten Moore, Irwin Nazareth, Rumana Z Omar, Victoria Vickerstaff, Louise Jones
BACKGROUND: Increasing number of people are dying with advanced dementia. Comfort and quality of life are key goals of care. AIMS: To describe (1) physical and psychological symptoms, (2) health and social care service utilisation and (3) care at end of life in people with advanced dementia. DESIGN: 9-month prospective cohort study. SETTING AND PARTICIPANTS: Greater London, England, people with advanced dementia (Functional Assessment Staging Scale 6e and above) from 14 nursing homes or their own homes...
August 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28918171/the-association-between-delirium-and-sarcopenia-in-older-adult-patients-admitted-to-acute-geriatrics-units-results-from-the-glisten-multicenter-observational-study
#16
Giuseppe Bellelli, Antonella Zambon, Stefano Volpato, Pasquale Abete, Lara Bianchi, Mario Bo, Antonio Cherubini, Francesco Corica, Mauro Di Bari, Marcello Maggio, Giovanna Maria Manca, Maria Rosaria Rizzo, Andrea Rossi, Francesco Landi
BACKGROUND & AIMS: To date, studies assessing the relationship between sarcopenia and delirium, two of the most common geriatric syndromes, are lacking. We sought to explore this association by investigating the co-occurrence of these two conditions and the independent association between them in a population of hospitalized older adults. METHODS: Cross-sectional multicenter analysis of older adults consecutively admitted to 12 acute geriatric units (AGUs). Sarcopenia was assessed upon admission by evaluating the presence of low skeletal mass index (kg/m(2)), and either low handgrip strength or low walking speed (European Working Group on Sarcopenia in Older People, EWGSOP criteria)...
September 5, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28913934/the-incidence-of-sarcopenia-among-hospitalized-older-patients-results-from-the-glisten-study
#17
Anna Maria Martone, Lara Bianchi, Pasquale Abete, Giuseppe Bellelli, Mario Bo, Antonio Cherubini, Francesco Corica, Mauro Di Bari, Marcello Maggio, Giovanna Maria Manca, Emanuele Marzetti, Maria Rosaria Rizzo, Andrea Rossi, Stefano Volpato, Francesco Landi
BACKGROUND: New evidence is emerging on the importance of lean body mass during periods of illness and recovery. The preservation of lean body mass during such periods of intense stress impacts both patient and treatment outcomes. However, data concerning the incidence of sarcopenia among older people during hospitalization are scarce. The objective of this study was to evaluate the development of sarcopenia in a sample of hospitalized older subjects. METHODS: We used data of 394 participants from the multicentre Italian Study conducted by the Gruppo Lavoro Italiano Sarcopenia-Trattamento e Nutrizione (GLISTEN) in 12 Acute Care Wards (Internal Medicine and Geriatrics) of University Hospitals across Italy...
September 14, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28905171/pharmacist-intervention-acceptance-for-the-reduction-of-potentially-inappropriate-drug-prescribing-in-acute-psychiatry
#18
Sophia Hannou, Pierre Voirol, André Pannatier, Marie-Laure Weibel, Farshid Sadeghipour, Armin von Gunten, Jean-Frédéric Mall, Isabella De Giorgi Salamun
Background Prescribing for the elderly is challenging. A previous observational study conducted in our geriatric psychiatry admission unit (GPAU) using STOPP/START criteria showed a high number of potentially inappropriate drug prescriptions (PIDPs). A clinical pharmacist was added to our GPAU as a strategy to reduce PIDPs. Objective The objective of the present study was to assess the impact of a clinical pharmacist on PIDPs by measuring acceptance rates of pharmacist interventions (PhIs). Setting This study was conducted at the GPAU of Lausanne University Hospital...
September 13, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28903581/geriatric-assessment-can-predict-outcomes-of-endoscopic-surgery-for-benign-prostatic-hyperplasia-in-elderly-patients
#19
Thomas Pichon, Cyrille Launay, Thibaut Culty, Denis Chautard, Nadine Collet, Nicolas Hoareau, Elena Brassart, Pierre Bigot, Olivier Beauchet, Abdel-Rahmene Azzouzi, Arnaud Cerruti, Souhil Lebdai
Ojectives: Surgical management of benign prostatic hyperplasia (BPH) in elderly patients is associated with higher morbidity and mortality. This arises the question of benefice and risk balance. We conducted a prospective observational study to evaluate the results of endoscopic surgery for BPH in elderly patients, according to geriatric assessment. PATIENTS AND METHODS: We included prospectively 60 patients over 75 years, with an indwelling catheter for acute or chronic retention, who were candidates to endoscopic surgery for BPH...
September 13, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28900726/-acute-and-emergency-care-of-geriatric-patients-old-ways-new-paths
#20
REVIEW
Katrin Singler, Hans Jürgen Heppner
No abstract text is available yet for this article.
September 12, 2017: Zeitschrift Für Gerontologie und Geriatrie
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