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https://www.readbyqxmd.com/read/27921633/healthcare-resources-are-inadequate-to-address-the-burden-of-illness-among-hiv-infected-male-prisoners-in-malaysia
#1
Joseph Bick, Gabriel Culbert, Haider A Al-Darraji, Clayton Koh, Veena Pillai, Adeeba Kamarulzaman, Frederick Altice
Purpose Criminalization of drug use in Malaysia has concentrated people who inject drugs (PWID) and people living with HIV into prisons where health services are minimal and HIV-related mortality is high. Few studies have comprehensively assessed the complex health needs of this population. The paper aims to discuss these issues. Design/methodology/approach From October 2012 through March 2013, 221 sequentially selected HIV-infected male prisoners underwent a comprehensive health assessment that included a structured history, physical examination, and clinically indicated diagnostic studies...
December 19, 2016: International Journal of Prisoner Health
https://www.readbyqxmd.com/read/27907848/fatal-and-non-fatal-overdose-after-narcology-hospital-discharge-among-russians-living-with-hiv-aids-who-inject-drugs
#2
Alexander Y Walley, Debbie M Cheng, Emily K Quinn, Elena Blokhina, Natalia Gnatienko, Christine E Chaisson, Evgeny Krupitsky, Philip O Coffin, Jeffrey H Samet
OBJECTIVES: Among Russians living with HIV/AIDS who inject drugs, we examined the incidence of fatal and non-fatal overdoses following discharge from a narcology hospital and the associations with more advanced HIV infection. DESIGN: Prospective cohort study of data collected at baseline, 3 and 6 months from HIV-infected patients with a history of injection drug use who were not treated with anti-retroviral therapy. Participants were recruited between 2012-2014 from a narcology (addiction) hospital in St...
November 28, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27898683/mortality-in-hiv-infected-alcohol-and-drug-users-in-st-petersburg-russia
#3
Nadia S Fairbairn, Alexander Y Walley, Debbie M Cheng, Emily Quinn, Carly Bridden, Christine Chaisson, Elena Blokhina, Dmitry Lioznov, Evgeny Krupitsky, Anita Raj, Jeffrey H Samet
In Russia, up to half of premature deaths are attributed to hazardous drinking. The respective roles of alcohol and drug use in premature death among people with HIV in Russia have not been described. Criminalization and stigmatization of substance use in Russia may also contribute to mortality. We explored whether alcohol, drug use and risk environment factors are associated with short-term mortality in HIV-infected Russians who use substances. Secondary analyses were conducted using prospective data collected at baseline, 6 and 12-months from HIV-infected people who use substances recruited between 2007-2010 from addiction and HIV care settings in a single urban setting of St...
2016: PloS One
https://www.readbyqxmd.com/read/27876616/the-starting-treatment-for-ethanol-in-primary-care-trials-step-trials-protocol-for-three-parallel-multi-site-stepped-care-effectiveness-studies-for-unhealthy-alcohol-use-in-hiv-positive-patients
#4
E Jennifer Edelman, Stephen A Maisto, Nathan B Hansen, Christopher J Cutter, James Dziura, Lynn E Fiellin, Patrick G O'Connor, Roger Bedimo, Cynthia Gibert, Vincent C Marconi, David Rimland, Maria C Rodriguez-Barradas, Michael S Simberkoff, Amy C Justice, Kendall J Bryant, David A Fiellin
Unhealthy alcohol use is common among HIV-positive patients, yet effective evidence-based treatments are rarely provided in clinical settings providing HIV care. Further, given patient variability in response to initial treatments, stepped care approaches may be beneficial. We describe the rationale, aims and study design for the current StartingTreatment forEthanol inPrimary care Trials (STEP Trials); three parallel randomized controlled effectiveness trials being conducted in five Infectious Disease Clinics...
November 20, 2016: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/27876048/an-integrated-approach-to-care-attracts-people-living-with-hiv-who-use-illicit-drugs-in-an-urban-centre-with-a-concentrated-hiv-epidemic
#5
S Fernando, R McNeil, K Closson, H Samji, S Kirkland, C Strike, R Baltzer Turje, W Zhang, R S Hogg, S Parashar
BACKGROUND: People living with HIV (PLHIV) who are also marginalized by social and structural inequities often face barriers to accessing and adhering to HIV treatment and care. The Dr. Peter Centre (DPC) is a non-profit integrated care facility with a supervised injection room that serves PLHIV experiencing multiple barriers to social and health services in Vancouver, Canada. This study examines whether the DPC is successful in drawing in PLHIV with complex health issues, including addiction...
November 22, 2016: Harm Reduction Journal
https://www.readbyqxmd.com/read/27871198/-it-is-easier-for-me-to-shoot-up-stigma-abandonment-and-why-hiv-positive-drug-users-in-russia-fail-to-link-to-hiv-care
#6
Tetiana Kiriazova, Karsten Lunze, Anita Raj, Natalia Bushara, Elena Blokhina, Evgeny Krupitsky, Carly Bridden, Dmitry Lioznov, Jeffrey H Samet, Allen L Gifford
Many HIV-positive people who inject drugs (PWID) globally are not receiving HIV care. This represents a major challenge among key populations to end the global HIV epidemic. This qualitative study explored the process and associated barriers of linking HIV-positive PWID who are in addiction treatment to HIV care in St. Petersburg, Russia. We conducted three focus groups and seven semi-structured interviews with participants in the LINC ("Linking Infectious and Narcology Care") project at addiction and HIV hospitals in St...
November 22, 2016: AIDS Care
https://www.readbyqxmd.com/read/27820957/survival-and-predictors-of-mortality-among-hiv-patients-on-anti-retroviral-treatment-at-jinka-hospital-south-omo-ethiopia
#7
Erdaw Tachbele Betre, Gobena Ameni
Purpose: Survival rate of HIV-infected patients on treatment are poorly understood in Ethiopia. The study aimed to determine the probability of survival and predictors of mortality, among HIV-infected adults on antiretroviral therapy in Jinka Hospital, South Omo, Ethiopia. Methods: A six years retrospective cohort study was conducted using 350 patient records among 1,899 antiretroviral therapy clients enrolled in Jinka hospital from September2010 - August 2015. Data was analysed using Kaplan Meier and Cox regression models...
November 6, 2016: Epidemiology and Health
https://www.readbyqxmd.com/read/27717364/meaningful-engagement-of-people-living-with-hiv-who-use-drugs-methodology-for-the-design-of-a-peer-research-associate-pra-hiring-model
#8
K Closson, R McNeil, P McDougall, S Fernando, A B Collins, R Baltzer Turje, T Howard, S Parashar
BACKGROUND: Community-based HIV, harm reduction, and addiction research increasingly involve members of affected communities as Peer Research Associates (PRAs)-individuals with common experiences to the participant population (e.g. people who use drugs, people living with HIV [PLHIV]). However, there is a paucity of literature detailing the operationalization of PRA hiring and thus limited understanding regarding how affected communities can be meaningfully involved through low-barrier engagement in paid positions within community-based participatory research (CBPR) projects...
October 7, 2016: Harm Reduction Journal
https://www.readbyqxmd.com/read/27715904/recent-incarceration-and-buprenorphine-maintenance-treatment-outcomes-among-hiv-positive-patients
#9
Daniel P Riggins, Chinazo O Cunningham, Yuming Ning, Aaron D Fox
BACKGROUND: Opioid use disorder is a common cause of morbidity and mortality among people living with HIV/AIDS. Buprenorphine maintenance treatment (BMT) is an effective means of therapy, but patients with recent criminal justice involvement may need more support during BMT than other patients. We hypothesized that recently incarcerated BMT patients who initiated treatment in primary care would have poorer treatment outcomes than those who were not recently incarcerated. METHODS: We analyzed data from a multi-site cohort study of BMT integrated into HIV care...
August 11, 2016: Substance Abuse
https://www.readbyqxmd.com/read/27668463/modeling-the-effects-of-morphine-on-simian-immunodeficiency-virus-dynamics
#10
Naveen K Vaidya, Ruy M Ribeiro, Alan S Perelson, Anil Kumar
Complications of HIV-1 infection in individuals who utilize drugs of abuse is a significant problem, because these drugs have been associated with higher virus replication and accelerated disease progression as well as severe neuropathogenesis. To gain further insight it is important to quantify the effects of drugs of abuse on HIV-1 infection dynamics. Here, we develop a mathematical model that incorporates experimentally observed effects of morphine on inducing HIV-1 co-receptor expression. For comparison we also considered viral dynamic models with cytolytic or noncytolytic effector cell responses...
September 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27659611/an-8-year-retrospective-study-of-human-visceral-leishmaniasis
#11
Juliana Ferreira Barbosa, Sônia Maria de Figueiredo, Sandra Lyon, Rachel Basques Caligiorne
Visceral leishmaniasis (VL) is azooanthroponosis affecting both rural and peri-urban areas, and can also spread into urban areas. Although more than 90% of new cases are reported from six countries: Bangladesh, Brazil, Ethiopia, India, South Sudan and Sudan, VL has emerged in many countries in the world, presenting new cases in new countries of occurrence. Thus, studies concerning epidemiological aspects in different world regions are very meaningful.In this purpose, this study aimed analyze 89 cases of VL, treated between June 2006 and June 2014 at Eduardo de Menezes Hospital (HEM), a Reference Center of Infectious Diseases situated in Belo Horizonte, in Minas Gerais state, Brazil...
September 21, 2016: Current Clinical Pharmacology
https://www.readbyqxmd.com/read/27650554/interactive-effects-of-ethanol-and-hiv-1-proteins-on-novelty-seeking-behaviors-and-addiction-related-gene-expression
#12
Taylor Wingo, Tanseli Nesil, Sulie L Chang, Ming D Li
BACKGROUND: Novelty-seeking behavior is related to the reward system in the brain and can predict the potential for addiction. Alcohol use is prevalent in HIV-1-infected patients and adversely affects antiretroviral medication. The difference in vulnerability to alcohol addiction between HIV-1-infected and noninfected populations has not been fully investigated. This study was designed to determine whether HIV-1 proteins alter the effects of ethanol (EtOH) on novelty-seeking behavior using the HIV-1 transgenic (HIV-1Tg) rat as the study model and to examine the molecular mechanisms responsible for this behavior...
October 2016: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/27638501/hazardous-alcohol-use-associated-with-increased-sexual-risk-behaviors-among-people-who-inject-drugs
#13
Nadia Fairbairn, Kanna Hayashi, M-J Milloy, Seonaid Nolan, Paul Nguyen, Evan Wood, Thomas Kerr
BACKGROUND: Alcohol is associated with a multitude of severe health consequences. While risk behaviors related to illicit drug use are commonly studied among people who inject drugs (PWID), the role of alcohol use has received substantially less attention in this population. We explored whether drug and sexual risk behaviors as well as experiences of violence were associated with hazardous alcohol use in a cohort of PWID. METHODS: Analyses were conducted using observational data from a prospective cohort of community-recruited HIV-negative PWID in Vancouver, Canada...
November 2016: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/27622164/pathways-to-addiction-a-gender-based-study-on-drug-use-in-a-triangular-clinic-and-drop-in-center-kerman-iran
#14
Farzaneh Zolala, Mina Mahdavian, Ali Akbar Haghdoost, Mohammad Karamouzian
BACKGROUND: Addiction is characterized differently among women and men, and they begin using drugs for different reasons and motives. OBJECTIVES: The aim of the study was to explore the gendered experiences and patterns of illicit drug use initiation in an Iranian context. PATIENTS AND METHODS: A total of 29 participants (15 men and 14 women) took part in in-depth interviews conducted at a HIV triangulation clinic (for men and women) and drop-in-center for women in Kerman in 2011...
June 2016: International Journal of High Risk Behaviors & Addiction
https://www.readbyqxmd.com/read/27617451/trends-of-mortality-and-causes-of-death-among-hiv-infected-persons-in-guadeloupe-1988-2009
#15
N Elenga, M T Ggeorger-Sow, T Messiaen, I Lamaury, I Favre, M Nacher, G Beaucaire
The aim of this study was to investigate the mortality rate, risk factors and causes of death among HIV-infected patients in Guadeloupe from 1988 to 2009. We used Kaplan-Meier analysis to describe the survival trends and the Cox proportional hazard model to identify predictors of deaths in HIV-infected patients. Mortality rate and causes of death were compared among patients whose HIV diagnosis was made in two different study periods. There were 672 deaths recorded. The exact cause of death was clearly identified for 202 patients (35%)...
September 18, 2015: West Indian Medical Journal
https://www.readbyqxmd.com/read/27601728/prevalence-of-hiv-hbv-and-hcv-among-street-and-labour-children-in-tehran-iran
#16
Maryam Foroughi, Saeedeh Moayedi-Nia, Alireza Shoghli, Saeed Bayanolhagh, Abbas Sedaghat, Mansoor Mohajeri, Seyed Noraldin Mousavinasab, Minoo Mohraz
OBJECTIVES: The existence of street and working children in Iran is undeniable. The precarious conditions of these children (including disrupted family, poverty, high prevalence of crime among relatives, family members and peers) cause social harm and high-risk behaviours, including drug addiction, selling sex or having sex with adolescents or peers. Here we explore the HIV, hepatitis B and hepatitis C status of street and working children in Tehran. METHODS: One thousand street and labour children, aged 10-18 years, were recruited by using the time-location sampling method, and semistructured questionnaires were used to find demographic information and information on HIV/AIDS-related high-risk sexual behaviours...
September 6, 2016: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/27568511/hiv-patients-preference-for-integrated-models-of-addiction-and-hiv-treatment-in-vietnam
#17
Diep Nguyen Bich, P Todd Korthuis, Trang Nguyen Thu, Hoa Van Dinh, Giang Le Minh
BACKGROUND: Integrated care models for HIV and substance use disorder (SUD) care are proposed as a strategy for closing gaps in the HIV care continuum and decreasing HIV transmission. We examined attitudes regarding integration of HIV and SUD treatment among HIV-infected patients with illicit drug and unhealthy alcohol use. METHOD: We conducted a cross-sectional survey of HIV-infected patients receiving care at 5 HIV clinics in Hanoi, Vietnam, regarding substance use and attitudes toward HIV and SUD treatment integration...
October 2016: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/27568260/heroin-addiction-methadone-and-hiv-in-china
#18
Carla Marienfeld
No abstract text is available yet for this article.
September 2016: Lancet Psychiatry
https://www.readbyqxmd.com/read/27568002/factors-associated-with-optimal-pharmacy-refill-adherence-for-antiretroviral-medications-and-plasma-hiv-rna-non-detectability-among-hiv-positive-crack-cocaine-users-a-prospective-cohort-study
#19
Kanna Hayashi, Evan Wood, Thomas Kerr, Huiru Dong, Paul Nguyen, Cathy M Puskas, Silvia Guillemi, Julio S G Montaner, Michael-John Milloy
BACKGROUND: Crack cocaine use is known to contribute to poor adherence to antiretroviral medications; however, little is known about facilitators of or barriers to effective HIV treatment use among HIV-infected crack cocaine users. We sought to identify correlates of optimal pharmacy refill adherence for antiretroviral medications and plasma HIV RNA viral load (pVL) suppression among this population. METHODS: Data from a prospective cohort of HIV-positive people who use illicit drugs in Vancouver, Canada, were linked to comprehensive HIV clinical monitoring and pharmacy dispensation records...
2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27528794/homelessness-hiv-and-incomplete-viral-suppression
#20
Kinna Thakarar, Jake R Morgan, Jessie M Gaeta, Carole Hohl, Mari-Lynn Drainoni
BACKGROUND: The importance of HIV viral suppression is widely known, however few studies have examined the effects of homelessness on HIV viral suppression. METHODS: The study included HIV-seropositive patients in a health care for the homeless program (HCH). Electronic medical record data for 138 patients were analyzed to compare demographic characteristics, health characteristics, and utilization by housing status. For the 95 individuals with available HIV viral loads, multivariable logistic analysis was performed to examine factors associated with incomplete viral suppression...
February 2016: Journal of Health Care for the Poor and Underserved
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