keyword
MENU ▼
Read by QxMD icon Read
search

sab

keyword
https://www.readbyqxmd.com/read/28078226/clinical-utility-of-sperm-dna-fragmentation-testing-practice-recommendations-based-on-clinical-scenarios
#1
REVIEW
Ashok Agarwal, Ahmad Majzoub, Sandro C Esteves, Edmund Ko, Ranjith Ramasamy, Armand Zini
Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for male fertility evaluation. While its detrimental implications on sperm function were extensively investigated, little is known about the actual indications for performing SDF analysis. This review delivers practice based recommendations on commonly encountered scenarios in the clinic. An illustrative description of the different SDF measurement techniques is presented. SDF testing is recommended in patients with clinical varicocele and borderline to normal semen parameters as it can better select varicocelectomy candidates...
December 2016: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28077780/exposure-to-crvi-during-early-pregnancy-increases-oxidative-stress-and-disrupts-the-expression-of-antioxidant-proteins-in-placental-compartments
#2
Sakhila K Banu, Jone A Stanley, Kirthiram K Sivakumar, Robert J Taylor, Joe A Arosh, Robert C Burghardt
Epidemiologic studies document relationships between chromium VI (CrVI) exposure and increased risk of spontaneous abortion, stillbirth, preterm birth, and neonatal death in pregnant women. Environmental contamination with CrVI is a growing problem both in the United States and developing countries. CrVI is widely used in numerous industries. This study was designed to understand the mechanism of CrVI toxicity on placental oxidative stress and antioxidant (AOX) machinery. Pregnant mother rats were treated with or without CrVI (50 ppm K2Cr2O7) through drinking water from gestational day (GD) 9...
November 15, 2016: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28076928/rxr%C3%AE-is-upregulated-in-first-trimester-endometrial-glands-of-spontaneous-abortions-unlike-lxr-and-ppar%C3%AE
#3
J Knabl, A Vattai, R Hüttenbrenner, S Hutter, M Karsten, U Jeschke
Nuclear receptors are necessary for uterine invasion of the trophoblast and therefore important for maintaining a viable pregnancy. The aim of this study was to investigate the expression pattern and frequency of LXR, PPARγ and RXRα under physiological circumstances and in spontaneous abortions in endometrial glands and decidual tissue cells. A total of 28 (14 physiologic pregnancies/14 spontaneous abortion) human pregnancies in first trimester were analysed for expression of the nuclear receptors LXR, RXRα and PPARγ...
November 2, 2016: European Journal of Histochemistry: EJH
https://www.readbyqxmd.com/read/28065221/meta-analysis-of-aspirin-heparin-therapy-for-un-explained-recurrent-miscarriage
#4
Tong Ling, Wei Xian-Jiang
Objective This study was designed to evaluate the efficacy and safety of aspirin-heparin treatment for un-explained recurrent spontaneous abortion (URSA). Methods Literatures reporting the studies on the aspirin-heparin treatment of un-explained recurrent miscarriage with randomized controlled trials (RCTs) were collected from the major publication databases. The live birth rate was used as primary indicator, preterm delivery, preeclampsia, intrauterine growth restriction, and adverse reactions (thrombocytopenia ) were used as the secondary indicators...
November 20, 2016: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/28051281/genetic-variation-in-leptin-and-leptin-receptor-genes-is-a-risk-factor-for-idiopathic-recurrent-spontaneous-abortion
#5
Andrijana Müller, Jasenka Wagner, Alenka Hodžić, Aleš Maver, Ivana Škrlec, Marija Heffer, Lada Zibar, Borut Peterlin
AIM: To determine whether maternal leptin (LEP) and leptin receptor (LEPR) gene polymorphisms are associated with idiopathic recurrent spontaneous abortion (IRSA). METHODS: This case-control association study conducted from 2010 to 2012 at the Department of Gynecology and Obstetrics, University Hospital Center Osijek and Clinical Institute of Medical Genetics Ljubljana included 178 women with a history of three or more IRSAs before the 22nd week of gestation and 145 women with at least two live births and no history of pathologic pregnancies during reproductive period...
December 31, 2016: Croatian Medical Journal
https://www.readbyqxmd.com/read/28042738/mir-520-promotes-dna-damage-induced-trophoblast-cell-apoptosis-by-targeting-parp1-in-recurrent-spontaneous-abortion-rsa
#6
Xiujuan Dong, Long Yang, Hui Wang
The establishment and maintenance of successful pregnancy mainly depends on trophoblast cells. Their dysfunction has been implicated in recurrent spontaneous abortion (RSA), a major complication of pregnancy. However, the underlying mechanisms of trophoblasts dysfunction remain unclear. DNA-damage-induced cell apoptosis has been reported to play a vital role in cell death. In this study, we identified a novel microRNA (miR-520) in RSA progression via regulating trophoblast cell apoptosis. Microarray analysis showed that miR-520 was highly expressed in villus of RSA patients...
December 31, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28042413/association-between-nutritional-status-with-spontaneous-abortion
#7
Rahimeh Ahmadi, Saeideh Ziaei, Sosan Parsay
BACKGROUND: Spontaneous abortion is the most common adverse pregnancy outcome. We aimed to investigate a possible link between nutrient deficiencies and the risk of spontaneous abortion. MATERIALS AND METHODS: This case-control study included the case group (n=331) experiencing a spontaneous abortion before 14 weeks of pregnancy and the control group (n=331) who were healthy pregnant women over 14 weeks of pregnancy. The participants filled out Food Frequency Questionnaire (FFQ), in which they reported their frequency of consumption for a given serving of each food item during the past three months, on a daily, weekly or monthly basis...
January 2017: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/28042412/molecular-detection-and-genotypic-characterization-of-toxoplasma-gondii-in-paraffin-embedded-fetoplacental-tissues-of-women-with-recurrent-spontaneous-abortion
#8
Amir Abdoli, Abdolhossein Dalimi, Haleh Soltanghoraee, Fatemeh Ghaffarifar
BACKGROUND: Congenital toxoplasmosis is an important cause of spontaneous abortion worldwide. However, there is limited information on detection and genotypic characterization of Toxoplasma gondii (T. gondii) in women with recurrent spontaneous abortion (RSA). The aim of this study is the molecular detection and genotypic characterization of T. gondii in formalin-fixed, paraffin-embedded fetoplacental tissues (FFPTs) of women with RSA that have referred to the Avicenna Research Institute in Tehran, Iran...
January 2017: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/28033536/cohort-study-of-the-incidence-of-spontaneous-preterm-birth-and-septic-abortion-referred-by-pathological-examination-in-gifu-prefecture-in-japan
#9
Yuichiro Takahashi, Shigenori Iwagaki, Mitsuaki Itoh, Hiromi Nakamura, Kazuo Kuwabara, Yuka Hiraku, Masashi Hori, Ryo Misao, Tatsuro Furui, Kenichiro Morishige
AIMS: To clarify the incidence of spontaneous preterm birth (PB) and septic abortion (sab) in Gifu prefecture in Japan. STUDY DESIGN: This prospective, population-based cohort study was approved by our hospital's Institutional Review Board. All 36 hospitals (100%) in Gifu prefecture offering obstetrical services participated in the study. Patient enrollment criteria were: sab and PB from 22 to <37weeks gestation (WG), excluding for maternal and fetal indications...
December 26, 2016: Early Human Development
https://www.readbyqxmd.com/read/28018578/dystrophic-mineralization-of-the-arterial-fibrovascular-tissue-associated-with-a-vitamin-d-hypervitaminosis-in-an-8-year-old-female-alpaca-vicugna-pacos
#10
Alexander Tavella, Annalisa Stefani, Claudia Zanardello, Astrid Bettini, Matthias Gauly, Patrik Zanolari
BACKGROUND: Prophylactic Vitamin D supplementation is a common practice in Alpaca breeding in many regions around the world. An overdosage can lead to dystrophic mineralization of soft tissues. In this paper we illustrate a suspected case of hypervitaminosis D in an 8-year-old female Alpaca. CASE PRESENTATION: In June 2015, the carcass of an 8-year-old female Alpaca (Vicugna pacos) was submitted to the diagnostic laboratory of the Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe) for necropsy...
2016: Irish Veterinary Journal
https://www.readbyqxmd.com/read/28013121/radiopharmaceutical-chemistry-of-targeted-radiotherapeutics-part-4-strategies-for-211-at-labeling-at-high-activities-and-radiation-doses-of-211-at-%C3%AE-particles
#11
Oscar R Pozzi, Michael R Zalutsky
INTRODUCTION: Alpha particles are radiation of high energy and short range, properties that can lead to radiolysis-mediated complications in labeling chemistry at the high radioactivity levels required for clinical application. In previous papers in this series, we have shown that radiation dose has a profound effect on the astatine species that are present in the labeling reaction and their suitability for the synthesis of N-succinimidyl 3-[(211)At]astatobenzoate. The purpose of this study was to evaluate the effects of adding N-chlorosuccinimide (NCS) to the methanol solution used for initial isolation of (211)At after distillation, a process referred to as (211)At stabilization, on (211)At chemistry after exposure to high radiation doses...
December 10, 2016: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/28012099/thrombocytopaenia-during-methicillin-sensitive-staphylococcus-aureus-bacteraemia
#12
E Forsblom, I Tielinen, E Ruotsalainen, A Järvinen
The prognostic impact of thrombocytopaenia in Staphylococcus aureus bacteraemia (SAB) has previously been determined at bacteraemia onset only and relevant pre-bacteraemic thrombocytopaenia predisposing parameters have not been accounted for. We evaluated the prognostic impact of low thrombocyte count in SAB excluding pre-bacteraemic factors potentially causing thrombocytopaenia. This was a multicentre retrospective analysis of methicillin-sensitive SAB (MS-SAB) patients. Thrombocyte count was determined at blood culture collection and at days 3 and 7...
December 23, 2016: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28007981/frontline-science-myeloid-derived-suppressor-cells-mdscs-facilitate-maternal-fetal-tolerance-in-mice
#13
Suzanne Ostrand-Rosenberg, Pratima Sinha, Chas Figley, Ramses Long, DoHwan Park, Darryl Carter, Virginia K Clements
During successful pregnancy, a woman is immunologically tolerant of her genetically and antigenically disparate fetus, a state known as maternal-fetal tolerance. How this state is maintained has puzzled investigators for more than half a century. Diverse, immune and nonimmune mechanisms have been proposed; however, these mechanisms appear to be unrelated and to act independently. A population of immune suppressive cells called myeloid-derived suppressor cells (MDSCs) accumulates in pregnant mice and women. Given the profound immune suppressive function of MDSCs, it has been suggested that this cell population may facilitate successful pregnancy by contributing to maternal-fetal tolerance...
December 22, 2016: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/27999028/relationship-between-vancomycin-tolerance-and-clinical-outcomes-in-staphylococcus-aureus-bacteraemia
#14
Nicholas S Britt, Nimish Patel, Theresa I Shireman, Wissam I El Atrouni, Rebecca T Horvat, Molly E Steed
BACKGROUND: Previous data have demonstrated the clinical importance of vancomycin MIC values in Staphylococcus aureus bacteraemia (SAB); however, the impact of vancomycin tolerance (VT) is unknown. OBJECTIVES: To compare the frequency of clinical failure between patients with VT and non-VT isolates in SAB. METHODS: This was a retrospective cohort study of patients with SAB, excluding treatment <48 h or polymicrobial bacteraemia. The primary outcome was clinical failure (composite of 30 day mortality, non-resolving signs and symptoms, and 60 day recurrence)...
December 20, 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27998857/-clinical-outcome-of-in-vitro-fertilization-or-intracytoplasmic-sperm-injection-embryo-transfer-in-women-aged-40-years-and-above
#15
Xing-Yu Zhou, Shu-Xian Feng, Xue-Lan Li, Yu-Dong Liu, Xin Chen, De-Sheng Ye, Jing Niu, Shi-Ling Chen
OBJECTIVE: To investigate the clinical outcomes in vitro fertilization or intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) in women aged over 40 years. METHODS: We retrospectively analyzed 1050 non-donor IVF/ICSI-ET cycles performed from January, 2007 to December, 2015 in women at the age 40 years or above, including 393 women at 40 years of age, 266 at 41 years, 158 at 42 years, 107 at 43 years, 64 at 44 years, and 65 at 45-51 years. The clinical characteristics and outcomes of the women in different age groups were compared and analyzed...
December 20, 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/27998308/semilobar-holoprosencephaly-in-a-12-month-old-baby-boy-born-to-a-primigravida-patient-with-type-1-diabetes-mellitus-a-case-report
#16
Pedro Pallangyo, Frederick Lyimo, Paulina Nicholaus, Hilda Makungu, Maria Mtolera, Isaac Mawenya
BACKGROUND: Holoprosencephaly is a rare spectrum of cephalic disorders resulting from a failure or incomplete division of the embryonic forebrain into distinct cerebral hemispheres. It is the most common brain malformation with an incidence of 1:250 during embryogenesis; however, owing to the associated high rates of spontaneous abortion the incidence is 1:16,000 among live deliveries. Pathogenesis of holoprosencephaly is complex and heterogeneous involving genetic abnormalities, teratogenic exposures, and syndromic associations...
December 20, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27997654/association-between-the-birth-of-an-infant-with-major-congenital-anomalies-and-subsequent-risk-of-mortality-in-their-mothers
#17
Eyal Cohen, Erzsébet Horváth-Puhó, Joel G Ray, Lars Pedersen, Nancy Adler, Anne Gulbech Ording, Paul H Wise, Arnold Milstein, Henrik Toft Sørensen
Importance: Giving birth to a child with a major birth defect is a serious life event for a woman, yet little is known about the long-term health consequences for the mother. Objective: To assess whether birth of an infant born with a major congenital anomaly was associated with higher maternal risk of mortality. Design, Setting, and Participants: This population-based cohort study (n = 455 250 women) used individual-level linked Danish registry data for mothers who gave birth to an infant with a major congenital anomaly (41 508) between 1979 and 2010, with follow-up until December 31, 2014...
20, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27997547/prevalence-of-antibodies-to-zika-virus-in-mothers-from-hawaii-who-delivered-babies-with-and-without-microcephaly-between-2009-2012
#18
Mukesh Kumar, Lauren Ching, Joshua Astern, Eunjung Lim, Alexander J Stokes, Marian Melish, Vivek R Nerurkar
Zika virus (ZIKV) is an emerging mosquito-borne pathogen. ZIKV infection is linked to the development of severe fetal abnormalities that include spontaneous abortion, stillbirth, hydranencephaly, and microcephaly. ZIKV outbreaks have been recorded in the United States. We recently demonstrated the first congenital ZIKV infection in the United States. In this study, we investigated archived blood samples from six mothers who gave birth to babies with microcephaly and 12 mothers who gave birth to healthy babies in Hawaii between 2009 and 2012...
December 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27993881/flow-cytometric-panel-reactive-antibody-results-and-the-ability-to-find-transfusion-compatible-platelets-after-antibody-desensitization-for-allogeneic-bone-marrow-transplant
#19
Eric R Rosenbaum, Soumya Pandey, Terry O Harville, Gina A Drobena, Michele Cottler-Fox
BACKGROUND: Panel reactive antibody (PRA) reduction protocols are used to decrease anti-HLA antibodies with concomitant PRA monitoring as a measure of successful treatment prior to organ and haploidentical blood and marrow transplant (BMT). We hypothesized that the more sensitive flow cytometry (FC) based assays for PRA [FlowPRA(®) and Luminex(®) based Single Antigen Bead (SAB)] would also correlate with the ability to find compatible platelets for allosensitized recipients. METHODS: A female patient with myelodysplastic syndrome and a high HLA class I PRA [>90% PRA and cPRA by complement-dependent cytotoxicity (CDC) assay and Flow PRA] required allogeneic BMT...
December 2016: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/27988917/is-the-perfusion-index-useful-in-early-detection-of-high-spinal-subarachnoid-block-during-cesarean-section
#20
Kazuhide Takeyama, Yosuke Suzuki, Masanobu Yoshikawa, Toshiyasu Suzuki
OBJECTIVE: To investigate the usefulness of the perfusion index (PI) in the early detection of high spinal subarachnoid block (SAB) for cesarean section (CS). METHOD: SAB was applied in patients of CS. The patients was subdivided into two groups, according to the highest level of block: the Ce group (cervical spine level) and the Th group (thoracic spine level). The PI values in the finger and toe, and vital signs were measured at pre- and post-SAB in both groups together with SAB level...
December 20, 2016: Tokai Journal of Experimental and Clinical Medicine
keyword
keyword
46430
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"