Tong Wu, Fangbo Zhang, Qingqing Cai, Hongwei Wu, Tong Jiang, Lixia Wang, Xiaoxu Chen, Peiyun Gao, Xiaoyun Yang, Yingying Chen, Chunyu Yue, Liying Tang, Zhuju Wang
Seven undescribed tannins, namely gejaponin A-G, and one dehydrodigallic acid derivative 3,4-dihydroxy-5-(3,4,5-trihydroxy-1-ethoxycarbonyl phenoxy)benzoic acid, together with eighteen known polyphenols were isolated from the 95% ethanol extract of the aerial part of Geum japonicum Thunb. var. chinense F. Bolle. Their structures were elucidated on the basis of comprehensive analysis of UV, IR, NMR, HRMS, and CD spectroscopy experiments. To evaluate their bioactivities, sixteen major compounds were selected to intervene in hydrogen peroxide (H2 O2 )-induced oxidative damage on H9c2 rat cardiomyoblasts...
November 27, 2023: Phytochemistry