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https://www.readbyqxmd.com/read/27936471/prevalence-of-lens-opacities-in-adult-chinese-americans-the-chinese-american-eye-study-ches
#1
Rohit Varma, Jie Sun, Mina Torres, Shuang Wu, Chunyi Hsu, Stanley Paul Azen, Roberta McKean-Cowdin
Purpose: We determined the age- and sex-specific prevalence of posterior subcapsular (PSC), nuclear, cortical, and mixed lens opacities in a population-based sample of Chinese-American adults. Methods: A population-based sample of Chinese-Americans 50 years and older, from 10 census tracts in Monterey Park, CA, USA, underwent a detailed interview and a comprehensive clinical examination that included assessment of different types of lens opacities by the slit-lamp-based Lens Opacities Classification System II (LOCS II)...
December 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27930795/optical-measurement-of-straylight-in-eyes-with-cataract
#2
Onurcan Sahin, Alexandros Pennos, Harilaos Ginis, Lucia Hervella, Eloy A Villegas, Belen Cañizares, Jose Maria Marin, Ioannis Pallikaris, Pablo Artal
PURPOSE: To measure straylight in a cohort of patients with cataract using a novel optical instrument and to correlate optical straylight values with clinical grade of cataracts and psychophysical straylight values. METHODS: Measurements were performed on 53 eyes of 44 patients with cataract admitted to the ophthalmology service of the university hospital in Murcia, Spain, and 9 young volunteers with no known ophthalmic pathology. Lens opacities were classified according to the Lens Opacities Classification System Ill (LOCS III) under slit-lamp examination...
December 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27923189/sensitive-immunoassay-based-detection-of-vibrio-parahaemolyticus-using-capture-and-labeling-particles-in-a-stationary-liquid-phase-lab-on-a-chip
#3
Byunghee Park, Suk-Jung Choi
In the present study, a method was developed for detection of Vibrio parahaemolyticus based on a stationary liquid phase lab-on-a-chip (SLP LOC). The present SLP LOC comprises a sample chamber, washing chamber, and detection chamber connected by two channels. The method utilizes two types of particles: capture particles (CPs), which are magnetic nanoparticles functionalized with antibody; and labeling particles (LPs), which are silica nanoparticles functionalized with horseradish peroxidase and antibody. Samples were added to the sample chamber with CPs and LPs, forming a CP-bacteria-LP complex, and the complex was transported to the detection chamber containing chromogenic substrate solution...
December 1, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27913121/loss-of-control-eating-after-sleeve-gastrectomy-surgery
#4
Valentina Ivezaj, Erin E Kessler, Janet A Lydecker, Rachel D Barnes, Marney A White, Carlos M Grilo
BACKGROUND: Postoperative loss-of-control (LOC) eating is related to poorer weight loss outcomes after bariatric surgery, but little is known about LOC eating after sleeve gastrectomy surgery. OBJECTIVES: To examine LOC eating severity and weight loss after sleeve gastrectomy SETTING: University School of Medicine, United States METHODS: Participants were 71 individuals (84.5% female; n = 60) who underwent sleeve gastrectomy surgery within the previous 4 to 9 months and reported LOC eating at least once weekly during the previous 28 days...
October 1, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/27912109/characterization-and-fine-mapping-of-a-novel-premature-leaf-senescence-mutant-yellow-leaf-and-dwarf-1-in-rice
#5
Luchang Deng, Peng Qin, Zhi Liu, Geling Wang, Weilan Chen, Jianhua Tong, Langtao Xiao, Bin Tu, Yuantao Sun, Wei Yan, Hang He, Jun Tan, Xuewei Chen, Yuping Wang, Shigui Li, Bingtian Ma
Leaves are the main organs in which photosynthates are produced. Leaf senescence facilitates the translocation of photosynthates and nutrients from source to sink, which is important for plant development and especially for crop yield. However, the molecular mechanism of leaf senescence is unknown. Here, we identified a mutant, yellow leaf and dwarf 1 (yld1), which exhibited decreased plant height and premature leaf senescence. Nitroblue tetrazolium and diamiobenzidine staining analyses revealed that the concentrations of reactive oxygen species were higher in yld1 leaves than in wild type leaves...
November 22, 2016: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/27905119/automatic-female-dehumanization-across-the-menstrual-cycle
#6
Valentina Piccoli, Carlo Fantoni, Francesco Foroni, Mauro Bianchi, Andrea Carnaghi
In this study, we investigate whether hormonal shifts during the menstrual cycle contribute to the dehumanization of other women and men. Female participants with different levels of likelihood of conception (LoC) completed a semantic priming paradigm in a lexical decision task. When the word 'woman' was the prime, animal words were more accessible in high versus low LoC whereas human words were more inhibited in the high versus low LoC. When the word 'man' was used as the prime, no difference was found in terms of accessibility between high and low LoC for either animal or human words...
November 30, 2016: British Journal of Social Psychology
https://www.readbyqxmd.com/read/27904812/predictor-effect-of-locus-of-control-loc-on-self-care-activities-and-metabolic-control-in-individuals-with-type-2-diabetes
#7
Dilek Büyükkaya Besen, Neslihan Günüşen, Hamdiye Arda Sürücü, Cansu Koşar
BACKGROUND: Previous studies have examined the role of individuals' personal characteristics in diabetes management and used the locus of control theory to assess adherence to a diabetes management regimen. These studies have emphasized that having internal locus of control may be a protective factor in diabetes management. OBJECTIVE: The purpose of this study is to determine the predictor effect of locus of control on self-care activities and A1c level. METHOD: The study is descriptive and relational...
2016: PeerJ
https://www.readbyqxmd.com/read/27903086/the-association-of-smokeless-tobacco-use-and-pack-years-of-smokeless-tobacco-with-age-related-macular-degeneration-in-indian-population
#8
Sangeetha Srinvasan, Gayathri Swaminathan, Vaitheeswaran Kulothungan, Tarun Sharma, Rajiv Raman
PURPOSE: To explore the association of use and the influence of pack-year use of smokeless tobacco versus no use with that of early and late age-related macular degeneration (AMD) in rural and urban south Indian population. We hypothesized that the use and pack-years of use would be significantly associated with both early and late AMD. We therefore sought to examine subjects who gave a history of using smokeless tobacco and we quantified the usage as pack-years, to examine the association with that of early and late AMD...
November 30, 2016: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/27902940/a-novel-lab-on-chip-platform-with-integrated-solid-phase-pcr-and-supercritical-angle-fluorescence-saf-microlens-array-for-highly-sensitive-and-multiplexed-pathogen-detection
#9
Tran Quang Hung, Wai Hoe Chin, Yi Sun, Anders Wolff, Dang Duong Bang
Solid-phase PCR (SP-PCR) has become increasingly popular for molecular diagnosis and there have been a few attempts to incorporate SP-PCR into lab-on-a-chip (LOC) devices. However, their applicability for on-line diagnosis is hindered by the lack of sensitive and portable on-chip optical detection technology. In this paper, we addressed this challenge by combining the SP-PCR with super critical angle fluorescence (SAF) microlens array embedded in a microchip. We fabricated miniaturized SAF microlens array as part of a microfluidic chamber in thermoplastic material and performed multiplexed SP-PCR directly on top of the SAF microlens array...
November 12, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27893730/fluorescent-nanodiamond-tracking-reveals-intraneuronal-transport-abnormalities-induced-by-brain-disease-related-genetic-risk-factors
#10
Simon Haziza, Nitin Mohan, Yann Loe-Mie, Aude-Marie Lepagnol-Bestel, Sophie Massou, Marie-Pierre Adam, Xuan Loc Le, Julia Viard, Christine Plancon, Rachel Daudin, Pascale Koebel, Emilie Dorard, Christiane Rose, Feng-Jen Hsieh, Chih-Che Wu, Brigitte Potier, Yann Herault, Carlo Sala, Aiden Corvin, Bernadette Allinquant, Huan-Cheng Chang, François Treussart, Michel Simonneau
Brain diseases such as autism and Alzheimer's disease (each inflicting >1% of the world population) involve a large network of genes displaying subtle changes in their expression. Abnormalities in intraneuronal transport have been linked to genetic risk factors found in patients, suggesting the relevance of measuring this key biological process. However, current techniques are not sensitive enough to detect minor abnormalities. Here we report a sensitive method to measure the changes in intraneuronal transport induced by brain-disease-related genetic risk factors using fluorescent nanodiamonds (FNDs)...
November 28, 2016: Nature Nanotechnology
https://www.readbyqxmd.com/read/27892475/droplet-merging-on-a-lab-on-a-chip-platform-by-uniform-magnetic-fields
#11
V B Varma, A Ray, Z M Wang, Z P Wang, R V Ramanujan
Droplet microfluidics offers a range of Lab-on-a-chip (LoC) applications. However, wireless and programmable manipulation of such droplets is a challenge. We address this challenge by experimental and modelling studies of uniform magnetic field induced merging of ferrofluid based droplets. Control of droplet velocity and merging was achieved through uniform magnetic field and flow rate ratio. Conditions for droplet merging with respect to droplet velocity were studied. Merging and mixing of colour dye + magnetite composite droplets was demonstrated...
November 28, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27884170/first-report-of-rickettsia-raoultii-and-r-slovaca-in-melophagus-ovinus-the-sheep-ked
#12
Dan Liu, Yuan-Zhi Wang, Huan Zhang, Zhi-Qiang Liu, Ha-Zi Wureli, Shi-Wei Wang, Chang-Chun Tu, Chuang-Fu Chen
BACKGROUND: Melophagus ovinus (Diptera: Hippoboscidae), a hematophagous ectoparasite, is mainly found in Europe, Northwestern Africa, and Asia. This wingless fly infests sheep, rabbits, and red foxes, and causes inflammation, wool loss and skin damage. Furthermore, this parasite has been shown to transmit diseases, and plays a role as a vector. Herein, we investigated the presence of various Rickettsia species in M. ovinus. METHODS: In this study, a total of 95 sheep keds were collected in Kuqa County and Alaer City southern region of Xinjiang Uygur Autonomous Region, northwestern China...
November 25, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27883138/characterization-of-size-dependent-mechanical-properties-of-tip-growing-cells-using-a-lab-on-chip-device
#13
Chengzhi Hu, Gautam Munglani, Hannes Vogler, Tohnyui Ndinyanka Fabrice, Naveen Shamsudhin, Falk K Wittel, Christoph Ringli, Ueli Grossniklaus, Hans J Herrmann, Bradley J Nelson
Quantification of mechanical properties of tissues, living cells, and cellular components is crucial for the modeling of plant developmental processes such as mechanotransduction. Pollen tubes are tip-growing cells that provide an ideal system to study the mechanical properties at the single cell level. In this article, a lab-on-a-chip (LOC) device is developed to quantitatively measure the biomechanical properties of lily (Lilium longiflorum) pollen tubes. A single pollen tube is fixed inside the microfluidic chip at a specific orientation and subjected to compression by a soft membrane...
November 24, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27881726/systems-genetics-identifies-a-novel-regulatory-domain-of-amylose-synthesis
#14
Vito M Butardo, Roslen Anacleto, Sabiha Parween, Irene Samson, Krishna de Guzman, Crisline Mae Alhambra, Gopal Misra, Nese Sreenivasulu
A deeper understanding of the regulation of starch biosynthesis in rice endosperm is crucial in tailoring digestibility without sacrificing grain quality. In this study, significant association peaks on chromosomes 6 and 7 were identified through genome-wide association study (GWAS) of debranched starch structure from grains of a 320 indica rice diversity panel using genotyping data from the high-density rice array. A systems genetics approach that interrelates starch structure data from GWAS to functional pathways from a gene regulatory network identified known and novel genes with high correlation to the proportion of amylose and amylopectin...
November 23, 2016: Plant Physiology
https://www.readbyqxmd.com/read/27876888/bph32-a-novel-gene-encoding-an-unknown-scr-domain-containing-protein-confers-resistance-against-the-brown-planthopper-in-rice
#15
Juansheng Ren, Fangyuan Gao, Xianting Wu, Xianjun Lu, Lihua Zeng, Jianqun Lv, Xiangwen Su, Hong Luo, Guangjun Ren
An urgent need exists to identify more brown planthopper (Nilaparvata lugens Stål, BPH) resistance genes, which will allow the development of rice varieties with resistance to BPH to counteract the increased incidence of this pest species. Here, using bioinformatics and DNA sequencing approaches, we identified a novel BPH resistance gene, LOC_Os06g03240 (MSU LOCUS ID), from the rice variety Ptb33 in the interval between the markers RM19291 and RM8072 on the short arm of chromosome 6, where a gene for resistance to BPH was mapped by Jirapong Jairin et al...
November 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27875742/map-based-cloning-and-characterization-of-the-novel-yellow-green-leaf-gene-ys83-in-rice-oryza-sativa
#16
Xiaozhi Ma, Xiaoqiu Sun, Chunmei Li, Rui Huan, Changhui Sun, Yang Wang, Fuliang Xiao, Qian Wang, Purui Chen, Furong Ma, Kuan Zhang, Pingrong Wang, Xiaojian Deng
Leaf-color mutants have been extensively studied in rice, and many corresponding genes have been identified up to now. However, leaf-color mutation mechanisms are diverse and still need further research through identification of novel genes. In the present paper, we isolated a leaf-color mutant, ys83, in rice (Oryza sativa). The mutant displayed a yellow-green leaf phenotype at seedling stage, and then slowly turned into light-green leaf from late tillering stage. In its yellow leaves, photosynthetic pigment contents significantly decreased and the chloroplast development was retarded...
November 9, 2016: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/27871243/osacos12-an-orthologue-of-arabidopsis-acyl-coa-synthetase5-plays-an-important-role-in-pollen-exine-formation-and-anther-development-in-rice
#17
Yueling Li, Dandan Li, Zongli Guo, Qiangsheng Shi, Shuangxi Xiong, Cheng Zhang, Jun Zhu, Zhongnan Yang
BACKGROUND: Sporopollenin is a major component of the pollen exine pattern. In Arabidopsis, acyl-CoA synthetase5 (ACOS5) is involved in sporopollenin precursor biosynthesis. In this study, we identified its orthologue, OsACOS12, in rice (Oryza sativa) and compared the functional conservation of ACOS in rice to Arabidopsis. RESULTS: Sequence analysis showed that OsACOS12 shares 63.9 % amino acid sequence identity with ACOS5. The osacos12 mutation caused by a pre-mature stop codon in LOC_Os04g24530 exhibits defective sexine resulting in a male sterile phenotype in rice...
November 21, 2016: BMC Plant Biology
https://www.readbyqxmd.com/read/27864027/patterns-of-neural-activity-predict-picture-naming-performance-of-a-patient-with-chronic-aphasia
#18
Yune Sang Lee, Jihad T Zreik, Roy H Hamilton
Naming objects represents a substantial challenge for patients with chronic aphasia. This could be in part because the reorganized compensatory language networks of persons with aphasia may be less stable than the intact language systems of healthy individuals. Here, we hypothesized that the degree of stability would be instantiated by spatially differential neural patterns rather than either increased or diminished amplitudes of neural activity within a putative compensatory language system. We recruited a chronic aphasic patient (KL; 66 year-old male) who exhibited a semantic deficit (e...
November 15, 2016: Neuropsychologia
https://www.readbyqxmd.com/read/27862949/a-weight-of-evidence-approach-for-deriving-a-level-of-concern-for-atrazine-that-is-protective-of-aquatic-plant-communities
#19
Dwayne Rj Moore, Colleen D Greer, Gillian Manning, Katie Wooding, Kerrie J Beckett, Richard A Brain, Gary Marshall
Atrazine is a selective triazine herbicide widely used in the United States primarily for control of broadleaf weeds in corn and sorghum. In 2003, the U.S. Environmental Protection Agency (USEPA) concluded that atrazine poses potential risks to sensitive aquatic species. Consequently, a surface water monitoring program was developed to assess whether measured levels of atrazine could impact aquatic plants in vulnerable watersheds. To facilitate evaluation of the monitoring data, the Agency needed to determine a level of concern (LOC) below which atrazine would not cause unacceptable adverse effects to aquatic plant communities...
November 11, 2016: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/27855547/traumatic-brain-injury-history-is-associated-with-earlier-age-of-onset-of-alzheimer-disease
#20
Christian LoBue, Hannah Wadsworth, Kristin Wilmoth, Matthew Clem, John Hart, Kyle B Womack, Nyaz Didehbani, Laura H Lacritz, Heidi C Rossetti, C Munro Cullum
OBJECTIVE: This study examined whether a history of traumatic brain injury (TBI) is associated with earlier onset of Alzheimer disease (AD), independent of apolipoprotein ε4 status (Apoe4) and gender. METHOD: Participants with a clinical diagnosis of AD (n = 7625) were obtained from the National Alzheimer's Coordinating Center Uniform Data Set, and categorized based on self-reported lifetime TBI with loss of consciousness (LOC) (TBI+ vs. TBI-) and presence of Apoe4...
November 18, 2016: Clinical Neuropsychologist
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