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https://www.readbyqxmd.com/read/28315366/amygdala-functional-connectivity-is-associated-with-locus-of-control-in-the-context-of-cognitive-aging
#1
Ping Ren, Mia Anthony, Benjamin P Chapman, Kathi Heffner, Feng Lin
Locus of control (LOC) measures the extent to which individuals perceive control over their lives. Those with a more "internal" LOC feel self-sufficient and able to determine important aspects of their own future, while those with a more "external" LOC feel that their lives are governed by events beyond their control. Reduced internal LOC and increased external LOC have been found in cognitive disorders, but the neural substrates of these control perceptions are yet unknown. In the present study, we explored the relationship between amygdala functional connectivity and LOC in 18 amnestic mild cognitive impairment (MCI) and age-, sex-, and education-matched, 22 cognitively healthy controls (HC)...
March 14, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28299682/microfluidic-arrayed-lab-on-a-chip-for-electrochemical-capacitive-detection-of-dna-hybridization-events
#2
Hadar Ben-Yoav, Peter H Dykstra, William E Bentley, Reza Ghodssi
A microfluidic electrochemical lab-on-a-chip (LOC) device for DNA hybridization detection has been developed. The device comprises a 3 × 3 array of microelectrodes integrated with a dual layer microfluidic valved manipulation system that provides controlled and automated capabilities for high throughput analysis of microliter volume samples. The surface of the microelectrodes is functionalized with single-stranded DNA (ssDNA) probes which enable specific detection of complementary ssDNA targets. These targets are detected by a capacitive technique which measures dielectric variation at the microelectrode-electrolyte interface due to DNA hybridization events...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28286847/protocol-adherence-in-prehospital-medical-care-provided-for-patients-with-chest-pain-and-loss-of-consciousness-a-brief-report
#3
Mostafa Mehrara, Nader Tavakoli, Marzieh Fathi, Babak Mahshidfar, Mohammad Amin Zare, Azita Asadi, Saeedeh Hosseinzadeh, Mehdi Safdarian
INTRODUCTION: Although many protocols are available in the field of the prehospital medical care (PMC), there is still a notable gap between protocol based directions and applied clinical practice. This study measures the rate of protocol adherence in PMC provided for patients with chest pain and loss of consciousness (LOC). METHOD: In this cross-sectional study, 10 educated research assistants audited the situation of provided PMC for non-traumatic chest pain and LOC patients, presenting to the emergency department of a tertiary level teaching hospital, compare to national recommendations in these regards...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28276552/surface-enhanced-raman-spectroscopy-and-microfluidic-platforms-challenges-solutions-and-potential-applications
#4
REVIEW
I J Jahn, O Žukovskaja, X-S Zheng, K Weber, T W Bocklitz, D Cialla-May, J Popp
The exhaustive body of literature published in the last four years on the development and application of systems based on surface-enhanced Raman spectroscopy (SERS) combined with microfluidic devices demonstrates that this research field is a current hot topic. This synergy, also referred to as lab-on-a-chip SERS (LoC-SERS) or nano/micro-optofluidics SERS, has opened the door for new opportunities where both techniques can profit. On the one hand, SERS measurements are considerably improved because the processes previously performed on a large scale in the laboratory and prone to human error can now be carried out in nanoliter volumes in an automatic and reproducible manner; on the other hand, microfluidic platforms need detection methods able to sense in small volumes and therefore, SERS is ideal for this task...
March 9, 2017: Analyst
https://www.readbyqxmd.com/read/28275744/editorial-concerning-long-term-outcomes-of-laparoscopic-versus-open-surgery-for-clinical-stage-i-gastric-cancer-the-loc-1-study
#5
EDITORIAL
Su Mi Kim, Ji Yeong An
No abstract text is available yet for this article.
2017: Transl Gastroenterol Hepatol
https://www.readbyqxmd.com/read/28267747/subjective-and-objective-cognitive-function-among-older-adults-with-a-history-of-traumatic-brain-injury-a-population-based-cohort-study
#6
Raquel C Gardner, Kenneth M Langa, Kristine Yaffe
BACKGROUND: Traumatic brain injury (TBI) is extremely common across the lifespan and is an established risk factor for dementia. The cognitive profile of the large and growing population of older adults with prior TBI who do not have a diagnosis of dementia, however, has not been well described. Our aim was to describe the cognitive profile associated with prior TBI exposure among community-dwelling older adults without dementia-an understudied but potentially vulnerable population. METHODS AND FINDINGS: In this population-based cohort study, we studied 984 community-dwelling older adults (age 51 y and older and their spouses) without dementia who had been randomly selected from respondents to the 2014 wave of the Health and Retirement Study to participate in a comprehensive TBI survey and who either reported no prior TBI (n = 737) or prior symptomatic TBI resulting in treatment in a hospital (n = 247)...
March 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28264984/the-lateral-occipital-cortex-loc-is-selective-for-object-shape-not-texture-color-at-6-months
#7
Lauren L Emberson, Stephen L Crosswhite, John E Richards, Richard N Aslin
Understanding how the human visual system develops is crucial to understanding the nature and organization of our complex and varied visual representations. However, previous investigations of the development of the visual system using fMRI are largely confined to a subset of the visual system (high-level vision: faces, scenes) and relatively late in visual development (starting at 4-5 years of age). The current study extends our understanding of human visual development by presenting the first systematic investigation of a mid-level visual region (the LOC) in a population much younger than has been investigated in the past - 6 month olds...
March 6, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28261537/are-limits-of-concern-a-useful-concept-to-improve-the-environmental-risk-assessment-of-gm-plants
#8
Marion Dolezel, Marianne Miklau, Andreas Heissenberger, Wolfram Reichenbecher
BACKGROUND: The European Food Safety Authority (EFSA) has introduced a concept for the environmental risk assessment of genetically modified (GM) plants which foresees the definition of ecological threshold values defining acceptable adverse effects of the GM plant on the environment (Limits of Concern, LoC). METHODS: We analysed the LoC concept by scrutinising its feasibility with regard to important aspects of the environmental risk assessment. We then considered its relationship with protection goals, the comparative safety assessment and the stepwise testing approach...
2017: Environmental Sciences Europe
https://www.readbyqxmd.com/read/28259321/school-based-oral-hygiene-education-program-has-long-term-positive-effects-on-oral-health-indicators
#9
Helena Silveira Schuch, Loc Giang Do
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Long-term effectiveness of school-based children oral hygiene program on oral health after 10-year follow-up. Lai H, Fann JC-Y, Yen AM-F, Chen L-S, Lai M-H, Chiu SY-H. Community Dent Oral Epidemiol 2016;44(3):209-15. SOURCE OF FUNDING: Information not available TYPE OF STUDY/DESIGN: Prospective cohort design.
March 2017: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/28258840/increased-prognostic-accuracy-of-tbi-when-a-brain-electrical-activity-biomarker-is-added-to-loss-of-consciousness-loc
#10
Dallas Hack, J Stephen Huff, Kenneth Curley, Roseanne Naunheim, Samanwoy Ghosh Dastidar, Leslie S Prichep
BACKGROUND: Extremely high accuracy for predicting CT+ traumatic brain injury (TBI) using a quantitative EEG (QEEG) based multivariate classification algorithm was demonstrated in an independent validation trial, in Emergency Department (ED) patients, using an easy to use handheld device. This study compares the predictive power using that algorithm (which includes LOC and amnesia), to the predictive power of LOC alone or LOC plus traumatic amnesia. PARTICIPANTS: ED patients 18-85years presenting within 72h of closed head injury, with GSC 12-15, were study candidates...
February 20, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28255458/brain-white-matter-impairment-in-patients-with-spinal-cord-injury
#11
Weimin Zheng, Qian Chen, Xin Chen, Lu Wan, Wen Qin, Zhigang Qi, Nan Chen, Kuncheng Li
It remains unknown whether spinal cord injury (SCI) could indirectly impair or reshape the white matter (WM) of human brain and whether these changes are correlated with injury severity, duration, or clinical performance. We choose tract-based spatial statistics (TBSS) to investigate the possible changes in whole-brain white matter integrity and their associations with clinical variables in fifteen patients with SCI. Compared with the healthy controls, the patients exhibited significant decreases in WM fractional anisotropy (FA) in the left angular gyrus (AG), right cerebellum (CB), left precentral gyrus (PreCG), left lateral occipital region (LOC), left superior longitudinal fasciculus (SLF), left supramarginal gyrus (SMG), and left postcentral gyrus (PostCG) (p < 0...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28251458/lifetime-number-of-ovulatory-cycles-and-epithelial-ovarian-cancer-risk-in-african-american-women
#12
Lauren C Peres, Patricia G Moorman, Anthony J Alberg, Elisa V Bandera, Jill Barnholtz-Sloan, Melissa Bondy, Michele L Cote, Ellen Funkhouser, Edward S Peters, Ann G Schwartz, Paul D Terry, Sarah E Abbott, Fabian Camacho, Frances Wang, Joellen M Schildkraut
PURPOSE: Incessant ovulation has been consistently linked to epithelial ovarian cancer (EOC). Although reproductive characteristics differ substantially by race, the association between incessant ovulation and EOC has been evaluated only in populations of predominantly white women. In the present study, we examined the association between lifetime number of ovulatory cycles (LOCs) and EOC risk among African American (AA) women. METHODS: We used data from 534 cases and 722 controls enrolled in the African American Cancer Epidemiology Study...
March 2, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28216123/ablation-of-the-auditory-cortex-results-in-changes-in-the-expression-of-neurotransmission-related-mrnas-in-the-cochlea
#13
Verónica Lamas, José M Juiz, Miguel A Merchán
The auditory cortex (AC) dynamically regulates responses of the Organ of Corti to sound through descending connections to both the medial (MOC) and lateral (LOC) olivocochlear efferent systems. We have recently provided evidence that AC has a reinforcement role in the responses to sound of the auditory brainstem nuclei. In a molecular level, we have shown that descending inputs from AC are needed to regulate the expression of molecules involved in outer hair cell (OHC) electromotility control, such as prestin and the α10 nicotinic acetylcholine receptor (nAchR)...
March 2017: Hearing Research
https://www.readbyqxmd.com/read/28215798/land-use-impacts-on-profile-distribution-of-labile-and-recalcitrant-carbon-in-the-ili-river-valley-northwest-china
#14
Xiang Liu, Lanhai Li, Zhiming Qi, Jiangang Han, Yongli Zhu
There is a growing evidence that the decomposition of recalcitrant carbon (C) can be stimulated by environmental changes, such as fresh C supply and increased temperature. However, the effect of land-use on profile distribution of recalcitrant C content is still poorly understood. In this study, soil samples were collected to a depth of 100cm from pastures and four major croplands including maize field, wheat field, paddy and apple orchard in the Ili River Valley, northwest China, to investigate the effects of land-use on profile distribution of labile organic C (LOC), semi-labile organic C (SLOC), recalcitrant organic C (ROC) and their relative proportions in total organic C (TOC), and evaluate whether such effects can be different between topsoil (0-20cm) and subsoil (20-100cm)...
May 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28213897/laryngo-onycho-cutaneous-like-syndrome-due-to-mutated-plectin
#15
Christine Prodinger, Alfred Klausegger, Anja Diem, Johann W Bauer, Martin Laimer
Laryngo-onycho-cutaneous syndrome (LOC) is a rare autosomal recessive genodermatosis that has been mainly described in the offspring of consanguineous families with origin in the Punjabi region of Pakistan and India [1]. Founder mutations affecting the LAMA3A gene on chromosome 18q11.2 have been implicated to underlie this syndrome [1,2]. Based on its molecular and clinical features, LOC was recently classified as a subtype of junctional Epidermolysis bullosa (JEB) [1]. This article is protected by copyright...
February 18, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28211993/recent-lab-on-chip-developments-for-novel-drug-discovery
#16
REVIEW
Nauman Khalid, Isao Kobayashi, Mitsutoshi Nakajima
Microelectromechanical systems (MEMS) and micro total analysis systems (μTAS) revolutionized the biochemical and electronic industries, and this miniaturization process became a key driver for many markets. Now, it is a driving force for innovations in life sciences, diagnostics, analytical sciences, and chemistry, which are called 'lab-on-a-chip, (LOC)' devices. The use of these devices allows the development of fast, portable, and easy-to-use systems with a high level of functional integration for applications such as point-of-care diagnostics, forensics, the analysis of biomolecules, environmental or food analysis, and drug development...
February 17, 2017: Wiley Interdisciplinary Reviews. Systems Biology and Medicine
https://www.readbyqxmd.com/read/28209532/stability-of-problematic-eating-behaviors-and-weight-loss-trajectories-after-bariatric-surgery-a-longitudinal-observational-study
#17
Eva M Conceição, James E Mitchell, Ana Pinto-Bastos, Filipa Arrojado, Isabel Brandão, Paulo P P Machado
BACKGROUND: The literature is rather mixed regarding the stability and the role of pre- and postoperative problematic eating behaviors (PEBs) on weight outcomes after bariatric surgery. OBJECTIVES: To investigate the stability of loss of control (LOC) eating and picking and/or nibbling from pre- to postoperative assessments, and to investigate whether pre- and postoperative PEBs are predictors of different weight loss trajectories. SETTING: Central Hospital, University, Portugal...
December 20, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28205485/asymptomatic-flexor-tendon-damages-after-volar-locking-plate-fixation-of-distal-radius-fractures
#18
Susumu Tokunaga, Yoshihiro Abe
BACKGROUND: To investigate asymptomatic flexor tendon damages after volar locking plate fixation of distal radius fractures in 32 wrists of 32 patients with distal radius fractures fixed using two plate types. Sixteen patients received the Acu-Loc volar distal radius plate, and the remaining 16 patients received the Aptus distal radius correction plate. METHODS: The flexor pollicis longus (FPL) tendon and flexor digitorum profundus were evaluated according to intraoperative findings at plate removal...
March 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28205275/psychometric-evaluation-of-the-youth-eating-disorder-examination-questionnaire-in-children-with-overweight-or-obesity
#19
Andrea E Kass, Kelly Theim Hurst, Rachel P Kolko, Elizabeth B Ruzicka, Richard I Stein, Brian E Saelens, R Robinson Welch, Michael G Perri, Kenneth B Schechtman, Leonard H Epstein, Denise E Wilfley
This study evaluated the psychometric properties of the Youth Eating Disorder Examination Questionnaire (YEDE-Q) and its utility for detecting loss of control (LOC) eating (i.e., eating episodes, regardless of size, involving a perceived inability to control what or how much one is eating) among school-age children with overweight or obesity. Identifying eating pathology, particularly LOC eating, in this population may facilitate treatment that improves weight outcomes and reduces eating disorder risk. Children with overweight or obesity (N = 241; 7-11 years) completed the YEDE-Q and abbreviated Child EDE (ChEDE) to assess LOC eating, prior to entering a weight management treatment trial...
February 15, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28203641/the-antecedents-of-women-s-external-locus-of-control-associations-with-characteristics-of-their-parents-and-their-early-childhood
#20
Jean Golding, Steven Gregory, Yasmin Iles-Caven, Stephen Nowicki
Locus of control (LOC) measures individuals' expectancies regarding their ability to affect what happens to them based on how they behave. The more they believe their behaviour has something to do with what happens to them the more internal they are. In contrast the more they perceive that what happens to them is beyond their control and determined by luck, fate, chance or powerful others the more external they are. Copious research findings suggest that external LOC (ELOC) is associated with many adverse personal, social, academic and health outcomes...
January 2017: Heliyon
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