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Jeffrey M Giddings, David Campana, Shyam Nair, Richard Brain
The U.S. Environmental Protection Agency (USEPA) has historically utilized different methods to derive an aquatic level of concern (LoC) for atrazine, though all have generally relied on an expanding set of mesocosm and microcosm ("cosm") studies for calibration. The database of results from ecological effects studies with atrazine in cosms now includes 108 data points from 39 studies and forms the basis for assessing atrazine's potential to impact aquatic plant communities. Inclusion of the appropriate cosm studies and accurate interpretation of each data point - delineated as binary scores of "effect" (effect score 1) or "no effect" (effect score 0) of a specific atrazine exposure profile on plant communities in a single study - is critical to USEPA's approach to determining the LoC...
April 16, 2018: Integrated Environmental Assessment and Management
Eva M Conceição, Marta de Lourdes, Ana Pinto-Bastos, Ana Rita Vaz, Isabel Brandão, Sofia Ramalho
OBJECTIVE: This study compares different problematic eating behaviors (PEBs; objective [OBE]/subjective [SBE] binge-eating and compulsive [CG]/noncompulsive [NCG] grazing) in relation to the severity of loss of control (LOC) and psychopathology. We also investigate LOC as a mediator between PEBs and psychopathology. METHOD: This cross-sectional study assessed a group of patients before bariatric surgery (n = 163), and a group of bariatric patients 12 months or more after surgery (n = 131)...
April 17, 2018: International Journal of Eating Disorders
Lindsay J McHenry, Ian G Stanistreet
Tuffaceous marker beds, derived from volcanic products from the Ngorongoro Volcanic Highlands, help define a stratigraphic framework for the world-renowned fossil and stone tool record exposed at Olduvai Gorge, Tanzania. However, previous efforts to constrain this tuff record, especially for Olduvai Bed II, have been limited because of erosion, contamination, reworking, and the alteration of volcanic glass under saline-alkaline conditions. This paper applies previously defined geochemical and mineralogical "fingerprints" for several major Bed II marker tuffs, based on glass (where available) and phenocrysts more resistant to alteration (feldspar, hornblende, augite, and titanomagnetite), to tuffs from stratigraphic sections in the Olduvai Junction Area, including previously and recently excavated Acheulean and Oldowan sites (HWK EE (Locality (Loc) 42), EF-HR (Loc 12a), FLK (Loc 45), and MNK (Loc 88))...
April 12, 2018: Journal of Human Evolution
Warn N Lekfuangfu, Nattavudh Powdthavee, Nele Warrinnier, Francesca Cornaglia
This article builds upon Cunha's (2015) subjective rationality model in which parents have a subjective belief about the impact of their investment on their children's early skill formation. We propose that this subjective belief is determined partly by locus of control (LOC), i.e. the extent to which individuals believe that their actions can influence future outcomes. Consistent with the theory, we show that maternal LOC measured at the 12th week of gestation strongly predicts maternal attitudes towards parenting style and actual time investments...
February 2018: Economic Journal
Yongxiang Liao, Que Bai, Peizhou Xu, Tingkai Wu, Daiming Guo, Yongbin Peng, Hongyu Zhang, Xiaoshu Deng, Xiaoqiong Chen, Ming Luo, Asif Ali, Wenming Wang, Xianjun Wu
Lesion mimic mutants display spontaneous cell death, and thus are valuable for understanding the molecular mechanism of cell death and disease resistance. Although a lot of such mutants have been characterized in rice, the relationship between lesion formation and abscisic acid (ABA) synthesis pathway is not reported. In the present study, we identified a rice mutant, lesion mimic mutant 9150 ( lmm9150 ), exhibiting spontaneous cell death, pre-harvest sprouting, enhanced growth, and resistance to rice bacterial and blast diseases...
2018: Frontiers in Plant Science
Archana Waganekar, Jagadish Sadasivan, A Sathia Prabhu, K T Harichandrakumar
Context: Based on Glasgow Coma Scale (GCS), head injury can be classified as minor (GCS 13-15), moderate (GCS 9-12), and severe (GCS 3-8). There is a lot of controversy in the use of computed tomography (CT) in head injury patients. Aims: This study was intended to estimate the rate of CT positivity in head injury patients and to define the criteria for doing CT in head injury patients. Settings and Design: This was a prospective observational study in the emergency department (ED) over a 12-month period...
January 2018: Journal of Emergencies, Trauma, and Shock
Andrea B Goldschmidt, Kathryn E Smith, Ross D Crosby, Hope K Boyd, Elizabeth Dougherty, Scott G Engel, Alissa Haedt-Matt
OBJECTIVES: Contextual factors related to maladaptive eating behavior in youth with overweight/obesity are poorly understood. This pilot study sought to elucidate immediate internal and external cues related to perceptions of overeating and loss of control (LOC) over eating in a heterogeneous sample of children and adolescents with overweight/obesity assessed in their natural environments. METHOD: Community-based youth [N = 40; 55% female (n = 22)], aged 8-14 y (M age = 11...
April 6, 2018: International Journal of Eating Disorders
Tze Hann Ng, Chia-Wei Lu, Shih-Shun Lin, Che-Chih Chang, Loc H Tran, Wen-Chi Chang, Chu-Fang Lo, Han-Ching Wang
An emerging bacterial disease, acute hepatopancreatic necrosis disease (AHPND), is caused by strains of Vibrio parahaemolyticus with an additional AHPND-associated plasmid pVA1 encoding a virulent toxin (Pirvp ) that damages the shrimp's hepatopancreas. Like other species of Vibrio, these virulent strains initially colonize the shrimp's stomach, but it is not yet understood how the bacteria or toxins are subsequently able to cross the epithelial barrier and reach the hepatopancreas. Here, by using transcriptomics and system biology methods, we investigate AHPND-induced changes in the stomach of AHPND-causing V...
April 6, 2018: Cellular Microbiology
Sung B Im, M Jalal Uddin, Gyeong J Jin, Joon S Shim
In this work, a low-cost PDMS micro-pump and -valve have been designed and developed to control multiple reagents for enzyme-linked immunosorbent assay (ELISA) on a programmable lab-on-a-chip (LOC) platform. The micro pump and valves were precisely controlled by selectively pressurizing the PDMS channels and chamber to actuate the multiple reagents in a controlled manner. Selective pressurizing of the PDMS structures was initiated by a simple system that maneuvered a single roller bar operated by a programmed microprocessor...
April 5, 2018: Lab on a Chip
Loc Luu, Anh Dinh
The aim of this study is on the investigation of motion noise removal techniques using two-accelerometer sensor system and various placements of the sensors on gentle movement and walking of the patients. A Wi-Fi based data acquisition system and a framework on Matlab are developed to collect and process data while the subjects are in motion. The tests include eight volunteers who have no record of heart disease. The walking and running data on the subjects are analyzed to find the minimal-noise bandwidth of the SCG signal...
April 2, 2018: Sensors
Krissana Boonpa, Supaluk Tantong, Kamonwan Weerawanich, Pawinee Panpetch, Onanong Pringsulaka, Yodying Yingchutrakul, Sittiruk Roytrakul, Supaart Sirikantaramas
According to an in silico analysis, OsGASR3 (LOC_Os03g55290) from rice (Oryza sativa L.) was predicted to be involved in plant defense mechanisms. A semi-quantitative reverse transcription polymerase chain reaction assay revealed that OsGASR3 is highly expressed in the inflorescences of Thai jasmine rice (O. sativa L. subsp. indica 'KDML 105'). To characterize the biological activity of OsGASR3, we produced an OsGASR3-glutathione S-transferase fusion protein in Escherichia coli Rosetta-gami (DE3) cells for a final purified recombinant OsGASR3 yield of 0...
March 27, 2018: Journal of Plant Physiology
Evaristus C Mbanefo, Loc Le, Luke F Pennington, Justin I Odegaard, Theodore S Jardetzky, Abdulaziz Alouffi, Franco H Falcone, Michael H Hsieh
Chemotherapy-induced hemorrhagic cystitis (CHC) can be difficult to manage. Prior work suggests that IL-4 alleviates ifosfamide-induced hemorrhagic cystitis (IHC), but systemically administered IL-4 causes significant side effects. We hypothesized that the Schistosoma hematobium homolog of IL-4-inducing principle from Schistosoma mansoni eggs (H-IPSE), would reduce IHC and associated bladder pathology. IPSE binds IgE on basophils and mast cells, triggering IL-4 secretion by these cells. IPSE is also an "infiltrin," translocating into the host nucleus to modulate gene transcription...
April 3, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Nora H Hope, Matthew A Wakefield, Lynnaea Northey, Alexander L Chapman
BACKGROUND: Locus of control (LOC) represents individuals' beliefs about how much control they have over outcomes in their life. Previous research has found an association between external LOC and psychopathology. Borderline personality disorder (BPD) is characterized by mood instability, identity disturbance and difficulties in impulse control. AIMS: The aims of this study are to evaluate the relationship between BPD features and LOC in a non-clinical sample and to assess whether external LOC is associated with BPD features after controlling for symptoms of depression and anxiety...
April 2, 2018: Personality and Mental Health
Lisa M Shank, Marian Tanofsky-Kraff, Rachel M Radin, Lauren B Shomaker, Denise E Wilfley, Jami F Young, Sheila Brady, Cara H Olsen, James C Reynolds, Jack A Yanovski
OBJECTIVE: Pediatric loss of control (LOC) eating prospectively predicts the worsening of metabolic syndrome components. However, it is unknown if remission of LOC eating is associated with improvements in metabolic health. Therefore, we conducted a secondary analysis of a trial that enrolled adolescent girls with LOC eating, examining whether LOC remission (vs. persistence) at end-of-treatment was associated with changes in metabolic syndrome components at 6-month follow-up. METHOD: One hundred three adolescent girls (age 14...
April 1, 2018: International Journal of Eating Disorders
Marco Bertamini, Juha Silvanto, Anthony M Norcia, Alexis D J Makin, Johan Wagemans
Symmetry is an important and prominent feature of the visual world. It has been studied as a basis for image segmentation and perceptual organization, but it also plays a role in higher level processes, such as face and object perception. Over the past decade, there has been progress in the study of the neural mechanisms of symmetry perception in humans and other animals. There is extended activity in the ventral stream, including the lateral occipital complex (LOC) and VO1; this activity starts in V3 and it occurs independently of the task (automatic response)...
March 31, 2018: Annals of the New York Academy of Sciences
Rahul Nair, Sana Ishaque, Andrew John Spencer, Liana Luzzi, Loc Giang Do
OBJECTIVES: Review the validation process reported for oral healthcare satisfaction scales that intended to measure general oral health care that is not restricted to specific subspecialties or interventions. METHODS: After preliminary searches, PUBMED and EMBASE were searched using a broad search strategy, followed by a snowball strategy using the references of the publications included from database searches. Title and abstract were screened for assessing inclusion, followed by a full-text screening of these publications...
March 30, 2018: Community Dentistry and Oral Epidemiology
Keren B Turton, Emily M Wilkerson, Alex S Hebert, Frances J Fogerty, Hazel M Schira, Fady E Botros, Joshua J Coon, Deane F Mosher
Genomic, transcriptomic and proteomic databases indicate that the N-terminal 322 residues encoded by the presumptive LOC100996504 gene, which is adjacent to the ARHGEF18 guanine nucleotide exchange factor gene on chromosome 19, constitute the N-terminal portion of a 1361-residue isoform of ARHGEF18, dubbed LOCGEF-X3. LOCGEF-X3 arises from the use of a leukocyte-specific alternative transcriptional start site and splicing that bypasses the initial noncoding exon of the canonical 1015-residue ARHGEF18 isoform, p114...
March 30, 2018: Journal of Leukocyte Biology
Wei Sun, Jia Liu, Jing Li, Di Wu, Jing Wang, Ming-Wu Wang, Jin-Song Zhang, Jiang-Yue Zhao
AIM: To evaluate human lens epithelium cell apoptosis and epithelial to mesenchymal transition (EMT) induced by femtosecond laser in femtosecond laser assisted cataract surgery (FLACS). METHODS: Sixty cataract patients with N2 to N3 stage according to the LOCS III were enrolled in this study and divided into three groups randomly: FLACS1 group (cataract surgery by FLACS with LenSx), FLACS2 group (cataract surgery by FLACS with LensAR) and manual group (cataract surgery by phacoemulsification)...
2018: International Journal of Ophthalmology
Thi Quynh Do, Bich Ngan Truong, Huong Doan Thi Mai, Thuy Linh Nguyen, Van Hung Nguyen, Hai Dang Nguyen, Tien Dat Nguyen, The Cuong Nguyen, Trieu Vung Luong, Loc Thang Giang, Van Minh Chau, Van Cuong Pham
Four new compounds N-salicyl-3-hydroxyanthranilic acid methyl ester (1), N-(2'-dehydroxysalicyl)-3-hydroxyanthranilic acid methyl ester (2), methyl-4-β-D-allopyranosyl-ferulate (3), and methyl-4-β-D-gulopyranosyl-cinnamate (4), along with six known compounds (5-10), were isolated from the roots of Aconitum carmichelii Debx. Their structures were elucidated on the basis of spectral data analysis, including 1D, 2D-NMR, and HR-ESI-MS. Compounds 1 and 2 showed the inhibition of nitric oxide (NO) production with IC50 values of 9...
March 30, 2018: Journal of Asian Natural Products Research
Krishna Chaitanya, Archana Addanki, Rajendra Karambelkar, Rakesh Ranjan
INTRODUCTION: Traumatic brain injury (TBI) in children and adolescents is a community-based medical and educational challenge world-over due to increasing urbanization and motorization. In India, children between 1 to 15 years constitute significant proportion of the total population, who are vulnerable for TBI. In developed countries, pediatric trauma mortality still represents more than half of all childhood fatalities, which is 18 times more common than brain tumors. In this study, we attempted to analyze epidemiological factors, management, and outcome of TBI in children at a tertiary care center in Pune, Maharashtra...
March 29, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
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