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beta-caryophyllene

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https://www.readbyqxmd.com/read/27871898/the-cannabinoid-beta-caryophyllene-bcp-induces-neuritogenesis-in-pc12-cells-by-a-cannabinoid-receptor-independent-mechanism
#1
Neife Aparecida Guinaim Santos, Nádia Maria Martins, Flávia Malvestio Sisti, Laís Silva Fernandes, Rafaela Scalco Ferreira, Osvaldo de Freitas, Antônio Cardozo Santos
Beta-caryophyllene (BCP) is a phytocannabinoid whose neuroprotective activity has been mainly associated with selective activation of cannabinoid-type-2 (CB2) receptors, inhibition of microglial activation and decrease of inflammation. Here, we addressed the potential of BCP to induce neuritogenesis in PC12 cells, a model system for primary neuronal cells that express trkA receptors, respond to NGF and do not express CB2 receptors. We demonstrated that BCP increases the survival and activates the NGF-specific receptor trkA in NGF-deprived PC12 cells, without increasing the expression of NGF itself...
November 18, 2016: Chemico-biological Interactions
https://www.readbyqxmd.com/read/27692687/corrigendum-to-beta-caryophyllene-modulates-expression-of-stress-response-genes-and-mediates-longevity-in-caenorhabditis-elegans-exp-gerontol-57-2014-81-95
#2
Aakanksha Pant, Shilpi K Saikia, Virendra Shukla, Jyotsna Asthana, Bashir A Akhoon, Rakesh Pandey
No abstract text is available yet for this article.
September 28, 2016: Experimental Gerontology
https://www.readbyqxmd.com/read/26299134/leaf-and-fruit-essential-oil-compositions-of-pimenta-guatemalensis-myrtaceae-from-costa-rica
#3
Carlos Chaverri, José F Cicció
Pitnenta is a genus of flowering plants in the Myrtaceae family, which has about 15 species, mostly found in the Caribbean region of the Americas. Commonly used for culinary and medicinal purposes, the best known commercial species are allspice, P. dioica (P. officinalis) and bay rum, P. racemosa, but there is little information concerning P. guatemalensis. The aim of the present study was to identify the chemical composition of the leaf and fruit essential oils ofP. guatemalensis. The extraction of essential oils of P...
March 2015: Revista de Biología Tropical
https://www.readbyqxmd.com/read/25442616/chemical-transformations-of-characteristic-hop-secondary-metabolites-in-relation-to-beer-properties-and-the-brewing-process-a-review
#4
REVIEW
Bart Steenackers, Luc De Cooman, Dirk De Vos
The annual production of hops (Humulus lupulus L.) exceeds 100,000 mt and is almost exclusively consumed by the brewing industry. The value of hops is attributed to their characteristic secondary metabolites; these metabolites are precursors which are transformed during the brewing process into important bittering, aromatising and preservative components with rather low efficiency. By selectively transforming these components off-line, both their utilisation efficiency and functionality can be significantly improved...
April 1, 2015: Food Chemistry
https://www.readbyqxmd.com/read/25374376/antigenotoxic-capacity-of-beta-caryophyllene-in-mouse-and-evaluation-of-its-antioxidant-and-gst-induction-activities
#5
Isela Alvarez-González, Eduardo Madrigal-Bujaidar, Seydi Castro-García
The present report was designed to determine the antigenotoxic capacity of beta-caryophyllene (BC) on the damage induced by benzo(a)pyrene (BaP) in mouse. We found no genotoxic potential of BC, and a significant inhibitory effect on the number of sister-chromatid exchanges (SCE) and chromosomal aberrations induced by BaP. The three tested doses of the agent (20, 200, and 2,000 mg/kg) produced a dose-dependent decrease of the two evaluated cytogenetic parameters. In comparison with the effect induced by BaP, the best inhibitory effect (about 80%) was obtained with the high tested dose of BC considering the two evaluated parameters...
2014: Journal of Toxicological Sciences
https://www.readbyqxmd.com/read/25312173/chemical-composition-antioxidant-activity-and-antibacterial-effect-of-essential-oil-of-the-aerial-parts-of-salvia-sclareoides
#6
Reza Sepahvand, Bahram Delfan, Saeed Ghanbarzadeh, Marzieh Rashidipour, Gholam Hassan Veiskarami, Javad Ghasemian-Yadegari
OBJECTIVE: To determine the chemical composition, antioxidant activity and antibacterial properties of essential oils of the aerial parts of Salvia sclareoides (S. sclareoides). METHODS: The essential oil of the areal parts of S. sclareoides was obtained by using hydrodistillation method and the composition of the volatile components analyzed by gas chromatography method coupled with mass spectrometry detector. The antimicrobial capacity of the essential oil of S...
September 2014: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/25230517/essential-oil-composition-and-antifungal-activity-of-aerial-parts-of-ballota-nigra-ssp-foetida-collected-at-flowering-and-fruiting-times
#7
Daniele Fraternale, Donata Ricci
The present study reports the results of gas chromatographic-mass spectrometric (GC/MS) analyses of the essential oils from the aerial parts of Ballota nigra L. ssp foetida (Lamiaceae) collected at flowering and fruiting times, as well as their in vitro antifungal activity against nine plant pathogenic fungi. Moreover, the essential oils were evaluated for their antifungal activity using the agar dilution method, and also MICs (minimum inhibitory concentrations) and MFCs (minimum fungicidal concentrations) were determined...
July 2014: Natural Product Communications
https://www.readbyqxmd.com/read/25230516/chemical-composition-antioxidant-antimicrobial-and-anti-inflammatory-activities-of-the-stem-and-leaf-essential-oils-from-piper-flaviflorum-from-xishuangbanna-sw-china
#8
Ren Li, Jing-Jing Yang, Yuan-Fei Wang, Qian Sun, Hu-Bin Hu
The present study is the first investigation of the chemical composition, antioxidant, antimicrobial and anti-inflammatory activities of the stem and leaf essential oils from Piper flaviflorum C.DC (SEOP and LEOP), a plant that has been consumed as a wild vegetable, and used as medicine, and spice by the ethnic groups in Xishuangbanna, SW China. Analyzed by GC-MS, 42 and 30 components were identified representing 90.1% and 95.3% of the SEOP and LEOP, with (E)-nerolidol (16.7% and 40.5%), beta-caryophyllene (26...
July 2014: Natural Product Communications
https://www.readbyqxmd.com/read/25230512/chemical-composition-of-vernonia-albicans-essential-oil-from-india
#9
Rajesh K Joshi
The chemical composition of the hydro-distilled essential oil obtained from the flowering aerial parts of Vernonia albicans DC. (Asteraceae) was analyzed by gas chromatography equipped with a flame ionization detector (GC-FID) and gas chromatography coupled with a mass spectrometry (GC/MS). Thirty-nine compounds have been identified, representing 97.5% of the total oil. The major constituents were beta-caryophyllene (34.3%), gamma-amorphene (19.5%), 9-epi-beta-caryophyllene (6.9%), and a-pinene (6.9%). The oil was found to be rich in sesquiterpene hydrocarbons (73...
July 2014: Natural Product Communications
https://www.readbyqxmd.com/read/25118415/chemical-composition-larvicidal-and-biting-deterrent-activity-of-essential-oils-of-two-subspecies-of-tanacetum-argenteum-asterales-asteraceae-and-individual-constituents-against-aedes-aegypti-diptera-culicidae
#10
Abbas Ali, Nurhayat Tabanca, Mine Kurkcuoglu, Ahmet Duran, Eugene K Blythe, Ikhlas A Khan, K Husnu Can Baser
Water-distilled essential oils from dried aerial parts of Tanacetum argenteum (Lam.) Willd. subsp. argenteum (Lam.) and T. argenteum (Lam.) Willd. subsp. canum (C. Koch) Grierson were analyzed by gas chromatography and gas chromatography-mass spectrometry. In total, 27 and 32 components were identified representing 97.2 and 98.7% of essential oils of subsp. argenteum and canum, respectively. Main compounds of T. argenteum subsp. argenteum were alpha-pinene (67.9%) and beta-pinene (4.8%), whereas alpha-pinene (53...
July 2014: Journal of Medical Entomology
https://www.readbyqxmd.com/read/25097659/in-vitro-and-in-vivo-characterization-of-the-new-analgesic-combination-beta-caryophyllene-and-docosahexaenoic-acid
#11
Paolo Fiorenzani, Stefania Lamponi, Agnese Magnani, Ilaria Ceccarelli, Anna Maria Aloisi
Beta-caryophyllene (BCP) and docosahexaenoic acid (DHA) are components of several plants with documented anti-inflammatory and analgesic effects in animal pain models. In the present study, in vitro and in vivo tests were carried out to evaluate their effects, alone or in combination, during long-lasting administration in a model of persistent pain. IR spectra of the two compounds were obtained to determine their chemical stability and then in vitro toxicity was evaluated in fibroblasts and astrocytes. In the in vivo tests, the analgesic effects of BCP and BCP+DHA were determined in male rats subjected to a model of persistent recurrent pain (three repetitions of the formalin test once a week) to mimic recurrent pain...
2014: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/25090672/-gc-ms-analysis-of-essential-oil-from-curcuma-aromatica-rhizome-of-different-growth-periods
#12
Jie Feng, Ming-ming Xu, Xiu-lan Huang, Hua-gang Liu, Mao-xiang Lai, Meng-han Wei
OBJECTIVE: To analyze the essential oil from the rhizome of Curcuma aromatica of different growth periods, and to provide the scientific reference for reasonable cultivation and quality control of this plant. METHODS: The essential oil was extracted by hydrodistillation and analyzed with GC-MS. The relative contents were determined with area normalization method. RESULTS: The main volatile constituents in the rhizome of Curcuma aromatica were basically the same...
December 2013: Zhong Yao Cai, Zhongyaocai, Journal of Chinese Medicinal Materials
https://www.readbyqxmd.com/read/24956819/-composition-and-antitumor-activities-of-essential-oil-from-the-fruits-of-dasymaschalon-trichophorum
#13
Xiao-bao Li, Guang-ying Chen, Xiao-ping Song, Chang-ri Han, Cai-juan Zheng
OBJECTIVE: To study the chemical components and antitumor activities of essential oil from the fruits of Dasymaschalon trichophorum. METHODS: The essential oil from the fruits of Dasymaschalon trichophorum was extracted by steam-stilling and analyzed by GC-MS. The inhibitory effect of extract of Dasymaschalon trichophorum on SPCA-1,BEL-7402, SGC-7901 and K-562 cell proliferation was assayed using the MTU. RESULTS: GC-MS result showed that there were 55 peaks and 30 compounds were identified which weighed 74...
November 2013: Zhong Yao Cai, Zhongyaocai, Journal of Chinese Medicinal Materials
https://www.readbyqxmd.com/read/24868866/styryllactones-and-acetogenins-from-the-fruits-of-goniothalamus-macrocalyx
#14
Quy Hung Trieu, Huong Doan Thi Mai, Van Cuong Pham, Marc Litaudon, Françoise Gueritte, Pascal Retailleau, Isabelle Schmitz-Afonso, Olinda Gimello, Van Hung Nguyen, Van Minh Chau
Two new styryllactones, macrocalactone (1) and 3-deoxycardiobutanolide (2), were isolated from the fruits of Goniothalamus macrocalyx Ban (Annonaceae), together with seven known compounds including four acetogenins, annonacin (3), solamin (4), isoannonacin (5), trans-murisolinone (6), and three other compounds, 7-acetylaltholactone (7), beta-caryophyllene-8R,9R-oxide (8) and 2-(2'-hydroxytetracosanoylamino)-octadecane-1,3,4-triol (9). Their structures were determined by spectroscopic and MS analysis. The absolute configuration of 1 was determined by X-ray crystallographic analysis...
April 2014: Natural Product Communications
https://www.readbyqxmd.com/read/24835194/beta-caryophyllene-modulates-expression-of-stress-response-genes-and-mediates-longevity-in-caenorhabditis-elegans
#15
Aakanksha Pant, Shilpi K Saikia, Virendra Shukla, Jyotsna Asthana, Bashir A Akhoon, Rakesh Pandey
Beta-caryophyllene (BCP) is a natural bicyclic sesquiterpene and is a FDA approved food additive, found as an active ingredient in essential oils of numerous edible plants. It possesses a wide range of biological activities including anti-oxidant, anti-inflammatory, anti-cancerous and local anesthetic actions. We used the well established Caenorhabditis elegans model system to elucidate the stress modulatory and lifespan prolonging action of BCP. The present study for the first time reports the lifespan extension and stress modulation potential of BCP in C...
September 2014: Experimental Gerontology
https://www.readbyqxmd.com/read/24689309/chemical-description-and-essential-oil-yield-variability-of-different-accessions-of-salvia-lavandulifolia
#16
Jaime Usano-Alemany, Jesús Palá-Paúl, Manuel Santa-Cruz Rodríguez, David Herraiz-Peñalver
The amount and chemical composition of essential oils are crucial for the modulation of the flavor, scent and therapeutic properties of aromatic and medicinal plants. The aim of this study was to evaluate the effects of phenology and weather conditions on the essential oil yield obtained from the aerial parts of Salvia lavandulifolia Vahl. Besides, we tried to carry out an approach to the chemical composition at the time of full bloom. Essential oil production of several accessions was monitored throughout the whole phenological cycle, both, at the original location growing wild and at the experimental plot as cultivated plants...
February 2014: Natural Product Communications
https://www.readbyqxmd.com/read/24689307/chemical-composition-of-the-essential-oil-of-croton-bonplandianus-from-india
#17
Rajesh K Joshi
The essential oil obtained from the aerial parts of Croton bonplandianus Baill. was analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). A total of 37 compounds have been identified, representing 96.2% of the total oil. The main constituents were identified as beta-caryophyllene (16.7%), germacrene D (14.7%), borneol (8.3%), Z-beta-damascenone (6.(%), isobornyl acetate (6.2%), alpha-humulene (6.1%), germacrene A (5.2%) and caryophyllene oxide (4.5%). The oil was rich in sesquiterpene hydrocarbons (60...
February 2014: Natural Product Communications
https://www.readbyqxmd.com/read/24660481/chemical-composition-of-the-essential-oil-from-croton-kimosorum-an-endemic-species-to-madagascar
#18
Delphin J R Rabehaja, Harilala Ihandriharison, Panja A R Ramanoelina, Rakotonirina Benja, Suzanne Ratsimamanga-Urverg, Ange Bighelli, Joseph Casanova, Félix Tomi
Croton kimosorum Leandri is an endemic species to Madagascar. The chemical composition of aerial parts, leaf and stem oils is reported for the first time. Analysis was carried out by combination of chromatographic (CC, GC), spectroscopic and spectrometric (MS, 13C NMR) techniques. In total, 76 compounds have been identified. Essential oil isolated from aerial parts contained mainly linalool (21.6%), sabinene (10.4%), 1,8-cineole (6.3%), beta-pinene (6.2%), (E)-beta-caryophyllene (5.9%), terpinen-4-ol (4.8%), geraniol (4,5%) and germacrene D (2...
January 2014: Natural Product Communications
https://www.readbyqxmd.com/read/24660479/chemical-composition-antioxidant-and-antimicrobial-activity-of-essential-oil-and-extracts-of-tragopogon-graminifolius-a-medicinal-herb-from-iran
#19
Mohammad Hosein Farzaei, Roja Rahimi, Farideh Attar, Farideh Siavoshi, Parastoo Saniee, Mannan Hajimahmoodi, Tahmineh Mirnezami, Mahnaz Khanavi
Tragopogon graminifolius DC., family Compositae, is widely consumed as a green vegetable in the west of Iran and for the treatment of gastrointestinal and hepatic ailments. In this study, the chemical composition of the essential oil from T. graminifolius aerial parts was evaluated by gas chromatography and gas chromatography mass spectrometry. Moreover, antioxidant and antimicrobial activity of the essential oil and various extracts of T. graminifolius were determined. Fifty-eight compounds representing 87...
January 2014: Natural Product Communications
https://www.readbyqxmd.com/read/24617143/comparison-of-the-volatile-oil-composition-of-three-atalantia-species
#20
COMPARATIVE STUDY
Arun K Das, P S Swamy
The members of the genus Atalantia belonging to the family Rutaceae have many uses in traditional medicine. The aim of the present study was to investigate and compare the chemical composition of essential oils of three species of Atalantia namely Atalantia monophylla (Roxb.) DC., Atalantia racemosa Wight. and Atalantia wightii Tanaka. The extract percentage of the obtained essential oil was found to be 0.2, 0.17 and 0.31% in A. monophylla, A. racemosa and A. wightii respectively. The major compounds identified were alpha-Asarone (28...
May 2013: Journal of Environmental Biology
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