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Esotropia

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https://www.readbyqxmd.com/read/28924312/outcome-of-early-surgery-in-infantile-esotropia-our-experience-in-tertiary-care-hospital
#1
Anirudh Singh, J K S Parihar, S K Mishra, R Maggon, Anurag Badhani
BACKGROUND: Infantile esotropia is a convergent strabismus presenting before 6 months of age and is the most common strabismus disorder presenting in the ophthalmology OPD. The dilemma of whether to go for early surgery and how early has been a matter of research for the last 50 years. We describe our results of surgery in infantile esotropia at variable age groups, as well as with different reoperation rates and compare with the results in western literature. METHODS: A prospective study was carried out through a review of 113 cases operated for infantile esotropia between February 2013 and August 2014...
April 2017: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28904567/intermittent-divergent-squint-in-prematurity-and-its-neurophysiological-aspects
#2
REVIEW
Kalpana Sharma, Praveen Panwar, Kulbhushan Prakash Chaudhary
Intermittent distance exotropia is a deviation characterized by an exophoria at near fixation and manifest exotropia at distance fixation. There is normal binocular fusional vergence and stereoacuity at near fixation, but the eyes tend to diverge in bright sunlight, tiredness, day dreaming and the patient may close one eye in such circumstances. Prematurity is associated with numerous eye pathology, besides retinopathy of prematurity, amblyopia, refractive errors, it is also associated with a higher risk esotropia and exotropia...
April 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28904218/early-onset-sixth-nerve-palsy-with-eccentric-fixation
#3
Kaajal D Nanda, Eve Lacey, Alki Liasis, Ken K Nischal
PURPOSE: To report four cases of early onset sixth-nerve palsy all of whom had eccentric fixation. METHODS: A retrospective case note review was undertaken of all cases presenting to the senior author's private and NHS practice with early onset sixth palsy between 2006 and 2012. As well as demographic information, details of ophthalmic, orthoptic, electrophysiological examinations, and radiological investigations that were extracted from the records. RESULTS: Four children with unilateral or asymmetric early onset sixth-nerve palsy were identified, of which three were congenital...
January 2017: American Orthoptic Journal
https://www.readbyqxmd.com/read/28878824/cma-analysis-identifies-homozygous-deletion-of-mcph1-in-2-brothers-with-primary-microcephaly-1
#4
Morteza Hemmat, Melissa J Rumple, Loretta W Mahon, Melanie Morrow, Tamara Zach, Arturo Anguiano, Mohamed M Elnaggar, Boris T Wang, Fatih Z Boyar
BACKGROUND: Homozygous mutations and deletions of the microcephalin gene (MCPH1; OMIM *607117) have been identified as a cause of autosomal recessive primary microcephaly and intellectual disability (MIM #251200). Previous studies in families of Asian descent suggest that the severity of the phenotype may vary based on the extent of the genomic alteration. We report chromosome microarray (CMA) findings and the first described family study of a patient with primary microcephaly in a consanguineous Hispanic family...
2017: Molecular Cytogenetics
https://www.readbyqxmd.com/read/28867397/factors-associated-with-atypical-postoperative-drift-following-surgery-for-consecutive-exotropia
#5
Steven D Maxfield, Sarah R Hatt, David A Leske, Jae Ho Jung, Jonathan M Holmes
PURPOSE: To evaluate the associations of clinical and surgical factors with atypical postoperative drift following surgery for consecutive exotropia. METHODS: A total of 66 patients with consecutive exotropia (≥10(Δ) at distance), after historical surgery for esotropia were retrospectively identified at a tertiary medical center. All patients underwent unilateral lateral rectus recession (on adjustable suture) with medial rectus advancement and/or resection. Immediate postoperative target angle was 4(Δ)-10(Δ) of esotropia at distance, anticipating mild postoperative exodrift...
August 31, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28864462/rapid-whole-genome-sequencing-identifies-a-novel-gabra1-variant-associated-with-west-syndrome
#6
Lauge Farnaes, Shareef A Nahas, Shimul Chowdhury, James Nelson, Serge Batalov, David M Dimmock, Stephen F Kingsmore
A 9-mo-old infant was admitted with infantile spasms that improved on administration of topiramate and steroids. He also had developmental delay, esotropia, and hypsarrhythmia on interictal electroencephalogram (EEG), and normal brain magnetic resonance imaging (MRI). West syndrome is the triad of infantile spasms, interictal hypsarrhythmia, and mental retardation. Rapid trio whole-genome sequencing (WGS) revealed a novel, likely pathogenic, de novo variant in the gene encoding γ-aminobutyric acid (GABA) type A receptor, α1 polypeptide (GABRA1 c...
September 2017: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/28860030/long-term-evaluation-of-two-reoperation-groups-for-intermittent-exotropia
#7
Ju-Yeun Lee, Ga-In Lee, Kyung-Ah Park, Sei Yeul Oh
PURPOSE: To evaluate the effect of initial postoperative deviation on subsequent reoperation in patients with intermittent exotropia and to compare the clinical factors and surgical outcomes between the two surgical failure groups. METHODS: The medical records of patients who underwent reoperation after failed primary surgery for intermittent exotropia at a single center were reviewed retrospectively. Patients with recurrent intermittent exotropia and consecutive esotropia were considered surgical failures...
August 28, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28859196/strabismus-incidence-in-a-danish-population-based-cohort-of-children
#8
Tobias Torp-Pedersen, Heather A Boyd, Line Skotte, Birgitte Haargaard, Jan Wohlfahrt, Jonathan M Holmes, Mads Melbye
Importance: To our knowledge, there have been few population-based studies of strabismus incidence conducted. Our population-based study provides valuable data for health services planning and identifying research needs. Objective: To determine the incidence and age distribution of strabismus, overall and by subtype, among children 7 years or younger. Design, Setting, and Participants: This population-based cohort study was conducted with data from 96 842 children enrolled in the Danish National Birth Cohort...
August 31, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28830623/remifentanil-a-help-in-topical-strabismus-surgery
#9
I Sánchez-Guillén, R López, M A Calle, A B Diez-Lobo
OBJECTIVE: To analyze the analgesic effect of remifentanil, side effects and complications in topical strabismus surgery. To study the results of strabismus surgery with this type of anesthesia. MATERIAL AND METHOD: Retrospective descriptive study. We included 39 patients undergoing strabismus surgery with topical anesthesia and analgesia-based sedation with remifentanil. The data of the anesthetic and surgical technique, surgical results and stability of the deviation angle were analyzed...
August 19, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28804647/y-split-recession-of-the-medial-rectus-muscle-as-a-secondary-and-or-unilateral-procedure-in-the-treatment-of-esotropia-with-distance-near-disparity
#10
Monika Wipf, Siegfried Priglinger, Anja Palmowski-Wolfe
INTRODUCTION: In esotropia with larger angles > near than at distance, splitting of the medial rectus muscle has been suggested as a treatment option. Previous reports of bilateral medial rectus Y-splitting as a first intervention showed a reduction of the distance/near disparity with fewer side effects compared to posterior fixation surgery. We address whether a medial rectus Y-splitting as a secondary and/or a unilateral procedure also reduce distance/near disparity. MATERIALS AND METHODS: We retrospectively reviewed the charts of four patients undergoing Y-split recession as a second and/or unilateral surgery...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28796570/pedigree-analysis-of-familial-primary-concomitant-horizontal-strabismus-in-northern-india
#11
Zia Chaudhuri, Jibin John, Satinder Aneja, B K Thelma
PURPOSE: Familial clustering of common forms of primary strabismus like esotropia (ET) and exotropia (XT) is observed in a proportion of the strabismus cohort. The genetic components of this remain unidentified. Linkage studies have demonstrated susceptibility locus for primary strabismus at the STBMS1 locus on 7p22.1 as well as other loci on 4q28.3 and 7q31.2. Recently next generation sequencing (NGS) technology has emerged as a powerful tool in discovery genomics and a large number of novel disease-causing variants are being reported...
August 10, 2017: Strabismus
https://www.readbyqxmd.com/read/28774524/clinical-profiles-and-surgical-outcomes-of-adult-esotropia
#12
Mikel Mikhail, Michael Flanders
OBJECTIVE: The aim of this study was to describe the clinical features and surgical outcomes of teenage and adult patients with esotropia undergoing strabismus surgery with adjustable sutures. METHODS: Seventy-three patients were included in this retrospective, cohort study. Patients were stratified into group 1 (35 with childhood-onset esotropia [CET]) and group 2 (38 with adult-onset esophoria-tropia [EPT]). Preoperative immediate, 2-week, and 4-6-month postoperative measurements of ocular alignment, as well as fusional testing, were performed...
August 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28759293/superior-and-lateral-rectus-myopexy-for-acquired-adult-distance-esotropia-a-one-size-fits-all-surgery
#13
Yair Morad, Eran Pras, Achia Nemet
AIM: To evaluate the results of bilateral lateral rectus to superior rectus myopexy for the treatment of acquired adult distance esotropia. METHODS: The charts of all adult patients who were operated for esotropia by the first author at the Department of Ophthalmology, Assaf Harofeh Medical Center, Tel Aviv University, Zrifin, Israel, between the years 2010-2015 were analyzed. Patients with the following inclusion criteria were included: acquired esotropia (not present during childhood); deviation greater for distance than near by at least 4 prism diopters (PD); slight abduction deficit in one or both eyes and/or displacement of the lateral rectus downwards as evident by CT/MRI with or without superior rectus nasal shift and no neurologic abnormalities such as cranial nerve palsies or other...
July 31, 2017: Strabismus
https://www.readbyqxmd.com/read/28757690/prognostic-preoperative-factors-for-successful-outcome-of-surgery-in-horizontal-strabismus
#14
Namita Kumari, Abadan Khan Amitava, Mohammad Ashraf, Shivani Grover, Ashiya Khan, Prabha Sonwani
CONTEXT: Surgery for horizontal strabismus reportedly has a success rate of 60%-80%. However, which preoperative factors are predictive of this success is not clear. AIMS: To identify prognostic factors those are predictive of successful outcome in horizontal strabismus surgery. SETTINGS AND DESIGN: Observational analytical study using multiple logistic regression (MLR). SUBJECTS AND METHODS: We assessed the medical records of patients who had undergone first-time horizontal muscle strabismus surgery between 2002 and 2013, where complete follow-up data were available for ≥6 weeks, and also, we collected data prospectively on patients operated between January 2014 and September 2015...
May 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/28744253/novel-eye-movement-disorders-in-whipple-s-disease-staircase-horizontal-saccades-gaze-evoked-nystagmus-and-esotropia
#15
Aasef G Shaikh, Fatema F Ghasia
Whipple's disease, a rare systemic infectious disorder, is complicated by the involvement of the central nervous system in about 5% of cases. Oscillations of the eyes and the jaw, called oculo-masticatory myorhythmia, are pathognomonic of the central nervous system involvement but are often absent. Typical manifestations of the central nervous system Whipple's disease are cognitive impairment, parkinsonism mimicking progressive supranuclear palsy with vertical saccade slowing, and up-gaze range limitation. We describe a unique patient with the central nervous system Whipple's disease who had typical features, including parkinsonism, cognitive impairment, and up-gaze limitation; but also had diplopia, esotropia with mild horizontal (abduction more than adduction) limitation, and vertigo...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28738831/outcomes-after-the-surgery-for-acquired-nonaccommodative-esotropia
#16
Eunbi Kim, Dong Gyu Choi
BACKGROUND: To analyze the surgical outcomes for patients diagnosed with acquired nonaccommodative esotropia (ANAET). METHODS: In this retrospective study, the medical records of 35 patients who had undergone the surgery for ANAET with a postoperative follow-up period of 6 months or more were reviewed. The main outcome measures were postoperative esodeviation angle, final success rate, and factors affecting surgical outcome. Surgical success was considered to be an alignment within 8 prism diopters (PD) at distance and near...
July 24, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28728290/-advances-in-research-of-divergence-insufficiency
#17
Y P Li, W Zhang
Divergence insufficiency is acquired esotropia at distance fixation with symptomatic uncrossed diplopia but fusion at near. It can be divided into two forms: primary isolated form and secondary form associated with neurologic abnormalities, also called divergence palsy. The clinical features of divergence insufficiency include small esotropia only at distance but orthotropia or small esophoria at near, comitant deviation at lateral gaze, reduced divergence fusion, full abduction and normal saccadic velocities in abduction...
July 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28724831/no-split-no-tenotomy-transposition-procedure-for-complete-abducens-palsy
#18
Sowmya Raveendra Murthy
Abducens palsy is one of the commonly encountered cranial nerve palsies in strabismus clinic. For large-angle esotropia, due to complete abducens palsies, various vertical recti transposition (VRT) procedures have been described. Hummelsheim and Jensen's procedure are especially popular among them. Risk of anterior segment ischemia and induced vertical deviation postVRT prompt to search for better procedures to correct the esotropia and also improve the abduction. Modified Nishida's procedure (no split, no tenotomy transposition) is one of the newly described procedure in this direction...
July 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28724819/stability-and-effects-of-muscle-transplantation-for-very-large-angle-esotropia-a-study-of-22-patients
#19
Jitendra Nenumal Jethani, Nirzari Shah, Sonal Amin, Monika Jethani
PURPOSE: A very large angle esotropia is characterized by an angle more than 80 prism diopters (pd). A single eye surgery would not correct such a large angle. Supramaximal recessions and resection would lead to restriction of ocular motility. We present a series of 22 patients with large angle esotropia treated with muscle transplantation. METHODS: A total of 22 patients (14 males and 8 females) were included in the study. All the patients had a minimum of 80 base out deviation in primary position...
July 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28711580/lateral-rectus-muscle-resection-following-maximal-recession-of-the-medial-rectus-muscle-in-thyroid-eye-disease
#20
Eric Weldy, Natalie C Kerr
BACKGROUND: Rectus muscle restriction is a common finding in thyroid eye disease (TED). Typically, restricted muscles are recessed to address strabismus and diplopia. However, some patients have residual strabismus following maximal recession of a restricted muscle. The purpose of this study was to report outcomes following resection of the lateral rectus muscle after maximal recession of the medial rectus muscle in patients with TED. METHODS: The medical records of patients with TED who underwent lateral rectus resection between 1998 and 2015 were reviewed retrospectively...
July 12, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
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