keyword
https://read.qxmd.com/read/38507520/james-watt-of-steam-engine-fame-offered-inhaled-carbon-monoxide-for-putative-therapeutic-action
#21
JOURNAL ARTICLE
Olivia W Xu, Jingping Wang, Theodore A Alston
James Watt (1736-1819) is remembered as a steam engine innovator and industrial magnate. A polymath, he was also a hands-on contributor to the Medical Pneumatic Institution of Thomas Beddoes. Watt recruited Humphry Davy, who there discovered analgesic action of inhaled nitrous oxide in 1799. Watt also built pneumatic equipment, and he introduced a gas mixture, dubbed hydro-carbonate, as a medical tonic. The bioactive component was carbon monoxide, a readily-lethal inhibitor of the transport and utilization of respiratory oxygen...
March 18, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38507495/a-thermally-conductive-martian-core-and-implications-for-its-dynamo-cessation
#22
JOURNAL ARTICLE
Wen-Pin Hsieh, Frédéric Deschamps, Yi-Chi Tsao, Takashi Yoshino, Jung-Fu Lin
Mars experienced a dynamo process that generated a global magnetic field ~4.3 (or earlier) to 3.6 billion years ago (Ga). The cessation of this dynamo strongly affected Mars' history and is expected to be linked to thermochemical evolution of Mars' iron-rich liquid core, which is strongly influenced by its thermal conductivity. Here, we directly measured thermal conductivities of solid iron-sulfur alloys to pressures relevant to the Martian core and temperatures to 1023 Kelvin. Our results show that a Martian core with 16 weight % sulfur has a thermal conductivity of ~19 to 32 Watt meter-1 Kelvin-1 from its top to the center, much higher than previously inferred from electrical resistivity measurements...
March 22, 2024: Science Advances
https://read.qxmd.com/read/38506167/novel-ternary-zintl-phosphide-halides-ba-3-p-5-x-x-cl-br-with-1d-helical-phosphorus-chains-synthesis-crystal-and-electronic-structure
#23
JOURNAL ARTICLE
Mohd Ishtiyak, S M Gayomi K Samarakoon, Thimira Kandabadage Don, Spencer R Watts, Sviatoslav Baranets
Black single crystals of two novel ternary phosphide halides, Ba3 P5 Cl and Ba3 P5 Br, were grown using molten metal Pb-flux high-temperature reactions. These compounds were structurally characterized with the aid of the single-crystal X-ray diffraction (SCXRD) method at 100(2) K. The SCXRD shows that both compounds are isostructural and adopt a new structure type (space group R 3̄ c , No. 167, Z = 6) with unit cell parameters a = 14.9481(16) Å, c = 7.3954(11) Å and a = 15.045(4) Å, c = 7...
March 20, 2024: Nanoscale
https://read.qxmd.com/read/38505797/validating-the-efficacy-and-value-proposition-of-mental-fitness-vocal-biomarkers-in-a-psychiatric-population-prospective-cohort-study
#24
JOURNAL ARTICLE
Erik Larsen, Olivia Murton, Xinyu Song, Dale Joachim, Devon Watts, Flavio Kapczinski, Lindsey Venesky, Gerald Hurowitz
BACKGROUND: The utility of vocal biomarkers for mental health assessment has gained increasing attention. This study aims to further this line of research by introducing a novel vocal scoring system designed to provide mental fitness tracking insights to users in real-world settings. METHODS: A prospective cohort study with 104 outpatient psychiatric participants was conducted to validate the "Mental Fitness Vocal Biomarker" (MFVB) score. The MFVB score was derived from eight vocal features, selected based on literature review...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38505759/can-peers-help-sustain-the-positive-effects-of-an-early-childhood-mathematics-intervention
#25
JOURNAL ARTICLE
Caroline Botvin, Jade M Jenkins, Robert C Carr, Kenneth A Dodge, Douglas Clements, Julie Sarama, Tyler W Watts
Our study assessed whether the peer environment in kindergarten and first grade affected student learning following an early mathematics intervention. We leveraged longitudinal data from a cluster-RCT to examine whether math achievement in kindergarten ( n = 1,218) and first grade ( n = 1,126) was affected by either the share of high-achieving classmates or the proportion of classroom peers who received a preschool math curriculum intervention. Analyses indicated that exposure to treated peers in first grade, but not kindergarten, was significantly associated with small gains in end-of-year achievement...
2024: Early Childhood Research Quarterly
https://read.qxmd.com/read/38504145/the-perceived-helpfulness-and-acceptability-of-a-bespoke-psychological-therapy-service-for-registered-nurses-experiencing-psychological-distress-a-qualitative-study
#26
JOURNAL ARTICLE
Dean Whybrow, Bethan Jones, Eunice Temeng, Carys Dale, Chris Bundy, Tessa Watts
AIM: To understand the perceived helpfulness and acceptability of a bespoke psychological therapy service for registered nurses. The service provided a free and confidential specialist mental health service to all healthcare professionals, including nurses and nursing students. DESIGN: An exploratory study using a descriptive qualitative approach. METHODS: A purposive sample of 20 registered nurses accessing a bespoke psychological therapy service in Wales participated in audio-recorded semi-structured interviews in January 2022...
March 19, 2024: Journal of Advanced Nursing
https://read.qxmd.com/read/38504091/social-disadvantage-and-multimorbidity-including-oral-conditions-in-the-united-states
#27
JOURNAL ARTICLE
A Mirza, R G Watt, A Heilmann, M Stennett, A Singh
Existing studies on multimorbidity have largely excluded oral diseases in multimorbidity prevalence estimates. The reason behind this is somewhat unclear, as chronic oral conditions are highly prevalent, affecting over half the global population. To address this gap, we examined the relationship between social disadvantage and multimorbidity, stratifying by the inclusion and exclusion of oral conditions. For participants aged 30 y and over ( n = 3,693), cross-sectional analysis was carried out using the US National Health and Nutrition Survey (2013-2014)...
March 19, 2024: Journal of Dental Research
https://read.qxmd.com/read/38503799/uncovering-the-hidden-structure-of-small-world-networks
#28
JOURNAL ARTICLE
Ahmed Lachgar, Abdelfattah Achahbar
The small-world (SW) network model introduced by Watts and Strogatz has significantly influenced the study of complex systems, spurring the development of network science as an interdisciplinary field. The Newman-Watts model is widely applied to analyze SW networks by adding several randomly placed shortcuts to a regular lattice. We meticulously examine related previous works and conclude that the scaling of various pertinent quantities lacks convincing evidence. We demonstrate that the SW property primarily stems from the existence of clusters of nodes linked by shortcuts rather than just the mean number of shortcuts...
March 19, 2024: Scientific Reports
https://read.qxmd.com/read/38499014/andrew-kerkhoff-award-winning-tb-and-hiv-physician-scientist
#29
JOURNAL ARTICLE
Geoff Watts
No abstract text is available yet for this article.
March 15, 2024: Lancet
https://read.qxmd.com/read/38493785/sir-michael-anthony-epstein
#30
JOURNAL ARTICLE
Geoff Watts
No abstract text is available yet for this article.
March 16, 2024: Lancet
https://read.qxmd.com/read/38490349/reducing-hydrophobic-drug-adsorption-in-an-in-vitro-extracorporeal-membrane-oxygenation-model
#31
JOURNAL ARTICLE
Nitish Khurana, Kamiya Watkins, Debika Ghatak, Jane Staples, Oliver Hubbard, Venkata Yellepeddi, Kevin Watt, Hamidreza Ghandehari
Extracorporeal membrane oxygenation (ECMO) is a life-saving cardiopulmonary bypass technology for critically ill patients with heart and lung failure. Patients treated with ECMO receive a range of drugs that are used to treat underlying diseases and critical illnesses. However, the dosing guidelines for these drugs used in ECMO patients are unclear. Mortality rate for patients on ECMO exceeds 40% partly due to inaccurate dosing information, caused in part by the adsorption of drugs in the ECMO circuit and its components...
March 13, 2024: European Journal of Pharmaceutics and Biopharmaceutics
https://read.qxmd.com/read/38490260/how-do-employees-in-the-disability-and-family-and-domestic-violence-sectors-respond-to-disclosures-of-violence-from-women-with-disability
#32
JOURNAL ARTICLE
Rebecca Waters, Jarla Anderson, Elise Gullotti, Gabrielle King, Demee Martin, David Hodgson, Lynelle Watts, Donna Chung
Women with disability experience higher rates of family and domestic violence (FDV) compared to the rest of the population. There is limited research into how workers in FDV and disability organizations respond to violence against women with disability. Using a case study vignette of a woman with disability disclosing FDV, this phenomenological study explored how 10 employees across the disability and FDV sectors respond to disclosures of abuse, the barriers that influenced their response, and suggested ways to improve their practices...
March 15, 2024: Violence Against Women
https://read.qxmd.com/read/38490183/rescue-of-a-lysosomal-storage-disorder-caused-by-grn-loss-of-function-with-a-brain-penetrant-progranulin-biologic
#33
Todd Logan, Matthew J Simon, Anil Rana, Gerald M Cherf, Ankita Srivastava, Sonnet S Davis, Ray Lieh Yoon Low, Chi-Lu Chiu, Meng Fang, Fen Huang, Akhil Bhalla, Ceyda Llapashtica, Rachel Prorok, Michelle E Pizzo, Meredith E K Calvert, Elizabeth W Sun, Jennifer Hsiao-Nakamoto, Yashas Rajendra, Katrina W Lexa, Devendra B Srivastava, Bettina van Lengerich, Junhua Wang, Yaneth Robles-Colmenares, Do Jin Kim, Joseph Duque, Melina Lenser, Timothy K Earr, Hoang Nguyen, Roni Chau, Buyankhishig Tsogtbaatar, Ritesh Ravi, Lukas L Skuja, Hilda Solanoy, Howard J Rosen, Bradley F Boeve, Adam L Boxer, Hilary W Heuer, Mark S Dennis, Mihalis S Kariolis, Kathryn M Monroe, Laralynne Przybyla, Pascal E Sanchez, Rene Meisner, Dolores Diaz, Kirk R Henne, Ryan J Watts, Anastasia G Henry, Kannan Gunasekaran, Giuseppe Astarita, Jung H Suh, Joseph W Lewcock, Sarah L DeVos, Gilbert Di Paolo
No abstract text is available yet for this article.
March 14, 2024: Cell
https://read.qxmd.com/read/38489854/who-is-most-vulnerable-factors-associated-with-presenting-to-antenatal-care-without-a-male-partner-in-northern-tanzania
#34
JOURNAL ARTICLE
Saumya S Sao, Jessica N Coleman, Linda Minja, Rimel N Mwamba, Godfrey A Kisigo, Haika Osaki, Jenny Renju, Blandina T Mmbaga, Melissa H Watt
OBJECTIVE: Male engagement in pregnancy care can be beneficial for maternal and child health outcomes. In Tanzania, pregnant women are strongly encouraged to present to their first antenatal care (ANC) appointment with a male partner, where they jointly test for HIV. For some, this presents a barrier to ANC attendance. The objectives of this study were to identify factors associated with presenting to ANC with a male partner using a cross-sectional design and to assess whether women presenting without partners had significantly delayed presentation...
February 29, 2024: Midwifery
https://read.qxmd.com/read/38489458/ghz-repetition-rate-sub-100-fs-ho-calgo-laser-at-2-1%C3%A2-%C3%A2%C2%B5m-with-watt-level-average-power
#35
JOURNAL ARTICLE
Weichao Yao, Mohsen Khalili, Yicheng Wang, Martin Hoffmann, Marcel van Delden, Thomas Musch, Clara J Saraceno
We report on a GHz fundamental repetition rate Kerr-lens mode-locked Ho:CALGO laser emitting at 2.1 µm. The laser employs a ring cavity to increase the fundamental repetition rate to 1.179 GHz and can be made to oscillate in both directions stably with nearly identical performance: for the counterclockwise oscillation, it generates 93-fs pulses at 1.68 W of average power, whereas 92 fs and 1.69 W were measured for the clockwise operation. Our current results represent the highest average power from a 2-µm GHz oscillator and, to our knowledge, the first sub-100-fs pulse duration from a Ho-based oscillator...
March 15, 2024: Optics Letters
https://read.qxmd.com/read/38486371/navigating-the-landscape-of-translational-geroscience-in-canada-a-comprehensive-evaluation-of-current-progress-and-future-directions
#36
JOURNAL ARTICLE
Guy Hajj-Boutros, Andréa Faust, John Muscedere, Perry Kim, Naji Abumrad, Stéphanie Chevalier, Mylene Aubertin-Leheudre, Howard Bergman, Dawn Bowdish, Jessica Burford, Stacy Carrington-Lawrence, Hélène Côté, David E Dawe, Philipe de Souto Barreto, Colin Farrelly, Robert Fowler, Gilles Gouspillou, Lea Harrington, Sofie Lautrup, Susan Howlett, Mahdi Imani, James Kirkland, George Kuchel, Frédérick A Mallette, José A Morais, John C Newman, Daryl Pullman, Felipe Sierra, Jeremy Van Raamsdonk, Jennifer Watt, R Jane Rylett, Gustavo Duque
The inaugural Canadian Conferences on Translational Geroscience were held as two complementary sessions in October and November 2023. The conferences explored the profound interplay between the biology of aging, social determinants of health, the potential societal impact of geroscience and the maintenance of health in aging individuals. Although topics such as cellular senescence, molecular and genetic determinants of aging and prevention of chronic disease were addressed, the conferences went on to emphasize practical applications for enhancing older people's quality of life...
March 15, 2024: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://read.qxmd.com/read/38486349/good-fit-is-weak-evidence-of-replication-increasing-rigor-through-prior-predictive-similarity-checking
#37
JOURNAL ARTICLE
Wes Bonifay, Sonja D Winter, Hanamori F Skoblow, Ashley L Watts
Replication provides a confrontation of psychological theory, not only in experimental research, but also in model-based research. Goodness of fit (GOF) of the original model to the replication data is routinely provided as meaningful evidence of replication. We demonstrate, however, that GOF obscures important differences between the original and replication studies. As an alternative, we present Bayesian prior predictive similarity checking: a tool for rigorously evaluating the degree to which the data patterns and parameter estimates of a model replication study resemble those of the original study...
March 14, 2024: Assessment
https://read.qxmd.com/read/38484768/reinjury-following-return-to-play
#38
JOURNAL ARTICLE
George J Watts V, Ryan Tai, Ganesh Joshi, Elisabeth Garwood, Debajyoti Saha
Radiologists are frequently called on for guidance regarding return to play (RTP) for athletes and active individuals after sustaining a musculoskeletal injury. Avoidance of reinjury is of particular importance throughout the rehabilitative process and following resumption of competitive activity. Understanding reinjury risk estimation, imaging patterns, and correlation of clinical and surgical findings will help prepare the radiologist to identify reinjuries correctly on diagnostic imaging studies and optimize management for a safe RTP...
April 2024: Seminars in Musculoskeletal Radiology
https://read.qxmd.com/read/38483759/assessing-the-spatial-distribution-of-elemental-concentrations-in-surface-sediments-of-lake-victoria-kenya-implications-for-ecological-health-and-management
#39
JOURNAL ARTICLE
C M Aura, O S Humphrey, A L Marriott, M J Watts, C O Ongore, J M Mwamburi, O Osano, T J Coffey
Lacustrine sediment quality indicates the effects of both natural and anthropogenic activities on the ecosystem and communities. Despite its ecological importance, myriad complexities, and potential contaminant sources, the spatial distribution of surficial sediments in Lake Victoria's Winam Gulf has never been comprehensively documented. The purpose of this study was to assess the spatial distribution, pathways, and ecological risk of metal elements in the lake using a sediment matrix. Sediment samples were collected throughout the gulf in November 2022...
March 14, 2024: Environmental Geochemistry and Health
https://read.qxmd.com/read/38483596/watts-happening-evaluation-of-thermal-dose-during-holmium-laser-lithotripsy-in-a-high-fidelity-anatomic-model
#40
JOURNAL ARTICLE
Christopher Wanderling, Aaron Saxton, Dennis Phan, Karen Doersch, Lauren Shepard, Nathan Schuler, Thomas Osinski, Scott Quarrier, Ahmed Ghazi
PURPOSE: To evaluate the thermal profiles of the holmium laser at different laser parameters at different locations in an in vitro anatomic pelvicalyceal collecting system (PCS) model. Laser lithotripsy is the cornerstone of treatment for urolithiasis. With the prevalence of high-powered lasers, stone ablation efficiency has become more pronounced. Patient safety remains paramount during surgery. It is well recognized that the heat generated from laser lithotripsy has the potential to cause thermal tissue damage...
March 14, 2024: World Journal of Urology
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