Daisuke Yamaguchi, Hidenori Hidaka, Takuya Matsunaga, Takashi Akutagawa, Yuichiro Tanaka, Amane Jubashi, Yuki Takeuchi, Nanae Tsuruoka, Yasuhisa Sakata, Koichi Miyahara, Naoyuki Tominaga, Hiroharu Kawakubo, Ayako Takamori, Ryo Shimoda, Takahiro Noda, Shinichi Ogata, Seiji Tsunada, Motohiro Esaki
BACKGROUND AND AIM: Elobixibat is a novel ileal bile acid transporter inhibitor. This study aimed to compare the efficacy, tolerability, and safety of the combination of elobixibat and 1 L of polyethylene glycol formulation containing ascorbic acid (PEG-Asc) solution versus the combination of sodium picosulfate and 1-L PEG-Asc solution as bowel preparation for colonoscopy. METHODS: This multi-center, randomized, observer-blinded, non-inferiority study recruited 210 outpatients who were assigned to either the elobixibat plus 1-L PEG-Asc group (group A) or the sodium picosulfate plus 1-L PEG-Asc group (group B)...
January 2022: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society