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https://www.readbyqxmd.com/read/29691863/population-based-study-of-mortality-and-major-amputation-following-lower-limb-revascularization
#1
K Heikkila, I M Loftus, D C Mitchell, A S Johal, S Waton, D A Cromwell
BACKGROUND: The aim of this study was to estimate separate risks of major lower limb amputation and death following revascularization for peripheral artery disease (PAD) using competing risks analysis. METHODS: Routinely collected data from Hospital Episode Statistics (HES) were used to identify patients who underwent endovascular or open lower limb revascularization for PAD in England from 2005 to 2015. The primary outcomes were major lower limb amputation and death within 5 years of revascularization...
April 25, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29691834/prescription-and-predictors-of-post-stroke-antidepressant-treatment-a-population-based-study
#2
J K Mortensen, S P Johnsen, G Andersen
OBJECTIVES: Post-stroke depression and pathological crying are common and potentially serious complications after stroke and should be diagnosed and treated accordingly. Diagnosis and treatment probably rely on clinical experience and may pose certain challenges. We aimed to examine prescription and predictors of antidepressant treatment after ischemic stroke in a clinical setting. MATERIALS AND METHODS: In this registry-based follow-up study, consecutive ischemic stroke patients were identified from the Danish Stroke Registry, holding information on antidepressant treatment during admission in Aarhus County from 2003 to 2010...
April 24, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29691617/mapping-functions-in-health-related-quality-of-life-mapping-from-the-achilles-tendon-rupture-score-to-the-eq-5d
#3
Ay-Yen Hua, Olof Westin, Eric Hamrin Senorski, Eleonor Svantesson, Alberto Grassi, Stefano Zaffagnini, Kristian Samuelsson, Mikael Svensson
PURPOSE: Health state utility values are derived from preference-based measurements and are useful in calculating quality-adjusted life years (QALYs), which is a metric commonly used in cost-effectiveness studies. The purpose of this study was to convert the Achilles Tendon Rupture Score (ATRS) to the preference-based European Quality of Life-5 Dimension Questionnaire (EQ-5D) by estimating the relationship between the two scores using mapping. METHODS: Data were collected from a randomised controlled trial, where 100 patients were treated either surgically or non-surgically for Achilles tendon rupture...
April 24, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29691213/an-mhealth-app-for-decision-making-support-in-wound-dressing-selection-wounds-protocol-for-a-user-centered-feasibility-study
#4
Scott Jordan, Jane McSwiggan, Joanne Parker, Gayle A Halas, Marcia Friesen
BACKGROUND: Primary care health professionals, especially family physicians, see a variety of wounds, and yet-despite the frequency of providing wound care-many family physicians do not feel confident in wound care management. This is partly due to a lack of formal wound education in Family Medicine programs. While there are numerous electronic wound care resources available in the UK and North America, none were identified that address the specific need in supporting clinical decision-making in wound dressing selection...
April 24, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29690553/pirna-profiling-of-dengue-virus-type-2-infected-asian-tiger-mosquito-and-midgut-tissues
#5
Yanhai Wang, Binbin Jin, Peiwen Liu, Jing Li, Xiaoguang Chen, Jinbao Gu
The Asian tiger mosquito, Aedes albopictus , is a competent vector for the majority of arboviruses. The mosquito innate immune response is a primary determinant for arthropod-borne virus transmission, and the midgut is the first barrier to pathogen transmission. Mosquito antiviral immunity is primarily mediated by the small interfering RNA pathway. However, the roles that the P-element induced wimpy testis (PIWI)-interacting RNA (piRNA) pathway play in antiviral immunity in Ae. albopictus and its midgut still need further exploration...
April 22, 2018: Viruses
https://www.readbyqxmd.com/read/29689661/design-and-efficacy-of-an-ecohealth-competency-based-course-on-the-prevention-and-control-of-vector-diseases-in-latin-america
#6
Laura Magaña-Valladares, Mario Henry Rodríguez, Ángel Francisco Betanzos-Reyes, Horacio Riojas-Rodríguez, María Laura Quezada-Jiménez, Juana Elvira Suárez-Conejero, Héctor Lamadrid-Figueroa
OBJECTIVE: To design and analyze the efficacy of an Ecohealth competency-based course on the prevention and control of vector-borne-diseases for specific stakeholders. MATERIALS AND METHODS: Multiple stakeholders and sectors of the region were consulted to identify Ecohealth group-specific competencies using an adjusted analysis matrix. Eight courses based on the competencies were implemented to train EA tutors. The effectiveness of the course was evaluated through the use of paired- t-tests by intervention group...
January 2018: Salud Pública de México
https://www.readbyqxmd.com/read/29689111/inter-relationships-between-objective-handwriting-features-and-executive-control-among-children-with-developmental-dysgraphia
#7
Sara Rosenblum
OBJECTIVE: To describe handwriting and executive control features and their inter-relationships among children with developmental dysgraphia, in comparison to controls. METHOD: Participants included 64 children, aged 10-12 years, 32 with dysgraphia based on the Handwriting Proficiency Screening Questionnaire (HPSQ) and 32 matched controls. Children copied a paragraph onto paper affixed to a digitizer that supplied handwriting process objective measures (Computerized Penmanship Evaluation Tool (ComPET)...
2018: PloS One
https://www.readbyqxmd.com/read/29689098/maternal-age-and-offspring-developmental-vulnerability-at-age-five-a-population-based-cohort-study-of-australian-children
#8
Kathleen Falster, Mark Hanly, Emily Banks, John Lynch, Georgina Chambers, Marni Brownell, Sandra Eades, Louisa Jorm
BACKGROUND: In recent decades, there has been a shift to later childbearing in high-income countries. There is limited large-scale evidence of the relationship between maternal age and child outcomes beyond the perinatal period. The objective of this study is to quantify a child's risk of developmental vulnerability at age five, according to their mother's age at childbirth. METHODS AND FINDINGS: Linkage of population-level perinatal, hospital, and birth registration datasets to data from the Australian Early Development Census (AEDC) and school enrolments in Australia's most populous state, New South Wales (NSW), enabled us to follow a cohort of 99,530 children from birth to their first year of school in 2009 or 2012...
April 2018: PLoS Medicine
https://www.readbyqxmd.com/read/29688855/critical-considerations-for-the-practical-utility-of-health-equity-tools-a-concept-mapping-study
#9
Bernadette Pauly, Wanda Martin, Kathleen Perkin, Thea van Roode, Albert Kwan, Tobie Patterson, Samantha Tong, Cheryl Prescott, Bruce Wallace, Trevor Hancock, Marjorie MacDonald
BACKGROUND: Promoting health equity within health systems is a priority and challenge worldwide. Health equity tools have been identified as one strategy for integrating health equity considerations into health systems. Although there has been a proliferation of health equity tools, there has been limited attention to evaluating these tools for their practicality and thus their likelihood for uptake. METHODS: Within the context of a large program of research, the Equity Lens in Public Health (ELPH), we conducted a concept mapping study to identify key elements and themes related to public health leaders and practitioners' views about what makes a health equity tool practical and useful...
April 23, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29688751/analysis-of-immediate-student-outcomes-following-a-change-in-gross-anatomy-laboratory-teaching-methodology
#10
Salman Afsharpour, Abigail Gonsalves, Ronald Hosek, Eric Partin
OBJECTIVE: To compare student performance following a change in laboratory teaching methodology from cadavers to models to virtual dissection table in a musculoskeletal gross anatomy course in a doctor of chiropractic program. METHODS: Three marking periods of laboratory and lecture examination scores from 3 consecutive academic calendar years were evaluated and compared using simple analysis as well as analysis of variance and post hoc t tests. The 1st cohort of students ( n = 352) utilized cadavers...
April 24, 2018: Journal of Chiropractic Education
https://www.readbyqxmd.com/read/29688108/a-novel-workplace-based-assessment-for-competency-based-decisions-and-learner-feedback
#11
Patricia J Hicks, Melissa J Margolis, Carol L Carraccio, Brian E Clauser, Kathleen Donnelly, H Barrett Fromme, Kimberly A Gifford, Sue E Poynter, Daniel J Schumacher, Alan Schwartz
BACKGROUND: Increased recognition of the importance of competency-based education and assessment has led to the need for practical and reliable methods to assess relevant skills in the workplace. METHODS: A novel milestone-based workplace assessment system was implemented in 15 pediatrics residency programs. The system provided: (1) web-based multisource feedback (MSF) and structured clinical observation (SCO) instruments that could be completed on any computer or mobile device; and (2) monthly feedback reports that included competency-level scores and recommendations for improvement...
April 24, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29688106/exploring-residents-reactions-to-and-use-of-parent-feedback-in-a-pediatric-emergency-department-a-grounded-theory-study
#12
Katherine A Moreau, Kaylee Eady, Mona Jabbour
BACKGROUND: Competency-based medical education (CBME) involves workplace-based assessment. In pediatrics, patients' parents can participate in this assessment and generate feedback for residents. Prior to routinely collecting parent feedback, it is important to investigate residents' perspectives on it. AIM: To explore residents' reactions to and use of written parent feedback. METHODS: Using a grounded theory approach, we interviewed residents who received written parent feedback at the mid- and end-points of a pediatric emergency training rotation...
April 24, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29687561/putting-the-c-into-cbt-cognitive-challenging-with-adults-with-mild-to-moderate-intellectual-disabilities-and-anxiety-disorders
#13
Lynette Roberts, Sophia Kwan
Individuals with intellectual disabilities (ID) are more vulnerable to mental health difficulties than the general population, yet there are limited evidence-based treatments available for this group. There has been a growing interest in adapting cognitive behaviour therapy (CBT) for this population; however, a framework describing how to modify cognitive challenging for a group characterized by cognitive impairment is lacking. The aim of this paper is threefold: (a) to describe how to implement cognitive challenging for adults with ID; (b) to report results from a pilot evaluation of a manualized, modified CBT-ID programme for anxiety; and (c) to compare participants with mild versus moderate ID on post-treatment cognitive challenging competencies...
April 23, 2018: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/29687420/from-agro-industrial-wastes-to-single-cell-oils-a-step-towards-prospective-biorefinery
#14
REVIEW
Batul Diwan, Piyush Parkhey, Pratima Gupta
The reserves of fossil-based fuels, which currently seem sufficient to meet the global demands, is inevitably on the verge of exhaustion. Contemporary raw material for alternate fuel like biodiesel is usually edible plant commodity oils, whose increasing public consumption rate raises the need of finding a non-edible and fungible alternate oil source. In this quest, single cell oils (SCO) from oleaginous yeasts and fungi can provide a sustainable alternate of not only functional but also valuable (polyunsaturated fatty acids (PUFA)-rich) lipids...
April 23, 2018: Folia Microbiologica
https://www.readbyqxmd.com/read/29686756/adapting-feedback-to-individual-residents-an-examination-of-preceptor-challenges-and-approaches
#15
Amanda Roze des Ordons, Adam Cheng, Jonathan Gaudet, James Downar, Jocelyn Lockyer
Background : Feedback conversations between preceptors and residents usually occur in closed settings. Little is known about how preceptors address the challenges posed by residents with different skill sets, performance levels, and personal contexts. Objective : This study explored the challenges that preceptors experienced and approaches taken in adapting feedback conversations to individual residents. Methods : In 2015, 18 preceptors participated in feedback simulations portraying residents with variations in skill, insight, confidence, and distress, followed by debriefing of the feedback conversation with a facilitator...
April 2018: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/29686751/leadership-training-in-graduate-medical-education-a-systematic-review
#16
REVIEW
Brett Sadowski, Sarah Cantrell, Adam Barelski, Patrick G O'Malley, Joshua D Hartzell
Background : Leadership is a critical component of physician competence, yet the best approaches for developing leadership skills for physicians in training remain undefined. Objective : We systematically reviewed the literature on existing leadership curricula in graduate medical education (GME) to inform leadership program development. Methods : Using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, we searched MEDLINE, ERIC, EMBASE, and MedEdPORTAL through October 2015 using search terms to capture GME leadership curricula...
April 2018: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/29686028/causes-and-temporal-patterns-of-30-day-readmission-among-older-adults-hospitalized-with-heart-failure-with-preserved-or-reduced-ejection-fraction
#17
Parag Goyal, Matthew Loop, Ligong Chen, Todd M Brown, Raegan W Durant, Monika M Safford, Emily B Levitan
BACKGROUND: It is unknown whether causes and temporal patterns of 30-day readmission vary between heart failure (HF) with preserved ejection fraction (HFpEF) and HF with reduced ejection fraction (HFrEF). We sought to address this question by examining a 5% national sample of Medicare beneficiaries. METHODS AND RESULTS: We included individuals who experienced a hospitalization for HFpEF or HFrEF between 2007 and 2013. We identified causes of 30-day readmission based on primary discharge diagnosis and further classified causes of readmission as HF-related, non-HF cardiovascular-related, and non-cardiovascular-related...
April 23, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29685392/cellular-therapies-day-by-day-all-the-way
#18
REVIEW
Erden Atilla, Pelin Kilic, Gunhan Gurman
Tremendous effort and knowledge have elucidated a new era of 'cellular therapy,' also called "live" or "living" drugs. There are currently thousands of active clinical trials that are ongoing, seeking hope for incurable conditions thanks to the increased accessibility and reliability of gene editing and cellular reprogramming. Accomplishments in various adoptive T cell immunotherapies and chimeric antigen receptor (CART) T cell therapies oriented researchers to the field. Cellular therapies are believed to be the next generation of curative therapeutics in many ways, the classification and nomenclature for these applications have not yet reached a consensus...
April 18, 2018: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/29684835/objectively-measured-interprofessional-education-outcome-and-factors-that-enhance-program-effectiveness-a-systematic-review
#19
REVIEW
R Riskiyana, M Claramita, G R Rahayu
Several studies have been conducted to evaluate the implementation of interprofessional education (IPE) across the globe. By looking at the timeline of each previous study, it can be inferred that the implementation of IPE has been improving continuously. However, the effectiveness of IPE still cannot be easily generalized due to misconceptions regarding how interprofessional collaboration capabilities should be evaluated. This study aims to generalize the learning outcomes that were produced by IPE in a global context and analyse the contributing factors...
April 17, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29684029/dispersion-and-oviposition-of-aedes-albopictus-in-a-brazilian-slum-initial-evidence-of-asian-tiger-mosquito-domiciliation-in-urban-environments
#20
Tania Ayllón, Daniel Cardoso Portela Câmara, Fernanda Cristina Morone, Larissa da Silva Gonçalves, Fábio Saito Monteiro de Barros, Patrícia Brasil, Marilia Sá Carvalho, Nildimar Alves Honório
Aedes albopictus, originally considered as a secondary vector for arbovirus transmission, especially in areas where this species co-exist with Aedes aegypti, has been described in most regions of the world. Dispersion and domiciliation of Ae. albopictus in a complex of densely urbanized slums in Rio de Janeiro, Southeastern Brazil, was evidenced. In this study, we tested the hypotheses that 1) Ae. albopictus distribution in urban slums is negatively related to distance from vegetation, and 2) these vectors have taken on a domestic life style with a portion of the population feeding, ovipositing, and resting indoors...
2018: PloS One
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