keyword
MENU ▼
Read by QxMD icon Read
search

Bicycling

keyword
https://www.readbyqxmd.com/read/28092224/visual-map-and-instruction-based-bicycle-navigation-a-comparison-of-effects-on-behaviour
#1
Dick de Waard, Frank Westerhuis, Danielle Joling, Stella Weiland, Ronja Stadtbäumer, Leonie Kaltofen
Cycling with a classic paper map was compared with navigating with a moving map displayed on a smartphone, and with auditory, and visual turn-by-turn route guidance. Spatial skills were found to be related to navigation performance, however only when navigating from a paper or electronic map, not with turn-by-turn (instruction based) navigation. While navigating, 25% of the time cyclists fixated at the devices that present visual information. Navigating from a paper map required most mental effort and both young and older cyclists preferred electronic over paper map navigation...
January 16, 2017: Ergonomics
https://www.readbyqxmd.com/read/28088011/particulates-and-noise-exposure-during-bicycle-bus-and-car-commuting-a-study-in-three-european-cities
#2
Enembe O Okokon, Tarja Yli-Tuomi, Anu W Turunen, Pekka Taimisto, Arto Pennanen, Ilias Vouitsis, Zissis Samaras, Marita Voogt, Menno Keuken, Timo Lanki
BACKGROUND: In order to curb traffic-related air pollution and its impact on the physical environment, contemporary city commuters are encouraged to shift from private car use to active or public transport modes. However, personal exposures to particulate matter (PM), black carbon and noise during commuting may be substantial. Therefore, studies comparing exposures during recommended modes of transport versus car trips are needed. METHODS: We measured personal exposure to various-sized particulates, soot, and noise during commuting by bicycle, bus and car in three European cities: Helsinki in Finland, Rotterdam in the Netherlands and Thessaloniki in Greece using portable monitoring devices...
January 11, 2017: Environmental Research
https://www.readbyqxmd.com/read/28075500/very-short-short-term-benefit-of-inpatient-outpatient-cardiac-rehabilitation-programs-after-coronary-artery-bypass-grafting-surgery
#3
Dejan Spiroski, Mojsije Andjić, Olivera Ilić Stojanović, Milica Lazović, Ana Djordjević Dikić, Miodrag Ostojić, Branko Beleslin, Snežana Kostić, Marija Zdravković, Dragan Lović
BACKGROUND: Exercise-based rehabilitation is an important part of treatment patients following coronary artery bypass graft (CABG) surgery. HYPOTHESIS: To evaluate effect of very short/short-term exercise training on cardiopulmonary exercise testing (CPET) parameters. METHODS: We studied 54 consecutive patients with myocardial infarction (MI) treated with CABG surgery referred for rehabilitation. The study population consisted of 50 men and 4 women (age 57...
January 11, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28074967/direct-enantioselective-c-acylation-for-the-construction-of-a-quaternary-stereocenter-catalyzed-by-a-chiral-bicyclic-imidazole
#4
Mo Wang, Xiao Zhang, Zheng Ling, Zhenfeng Zhang, Wanbin Zhang
A direct enantioselective C-acylation of 3-substituted benzofuran-2(3H)-ones (with up to 97% ee) was developed using a chiral bicyclic imidazole catalyst OAc-DPI and an achiral tertiary amine additive DIPEA. The reaction mechanism for the direct C-acylation has been investigated using both experimental and theoretical studies.
January 11, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28068656/mechanisms-of-improved-exercise-performance-under-hyperoxia
#5
Silvia Ulrich, Elisabeth D Hasler, Séverine Müller-Mottet, Stephan Keusch, Michael Furian, Tsogyal D Latshang, Simon Schneider, Stéphanie Saxer, Konrad E Bloch
BACKGROUND: The impact of hyperoxia on exercise limitation is still incompletely understood. OBJECTIVES: We investigated to which extent breathing hyperoxia enhances the exercise performance of healthy subjects and which physiologic mechanisms are involved. METHODS: A total of 32 healthy volunteers (43 ± 15 years, 12 women) performed 4 bicycle exercise tests to exhaustion with ramp and constant-load protocols (at 75% of the maximal workload [Wmax] on FiO2 0...
January 10, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28067686/persistent-knee-pain-after-falling-off-of-a-bicycle
#6
Muhammad Waseem, Julissa Garrido-Joyce, Frances Quee, Soula Priovolos
We present the case of an 18-year-old young man with severe persistent knee pain secondary to a popliteal artery thrombosis. This occurred as a result of a fall from a bicycle. Acute compartment syndrome refers to the sequelae that can occur because of increased fascial compartment pressures, such as crush injuries, burns, traumatic or spontaneous hemorrhage, or constrictive casts. Increased pressures in nonelastic fascial compartments result in decreased perfusion distally, leading to ischemia of muscles and neurovascular tissue...
January 6, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28067069/a-phytotoxic-bicyclic-lactone-and-other-compounds-from-endophyte-xylaria-curta
#7
Abdou Tchoukoua, Takuma Ota, Rima Akanuma, Yu-Ming Ju, Unang Supratman, Tetsuya Murayama, Takuya Koseki, Yoshihito Shiono
A new compound, (3aS,6aR)-4,5-dimethyl-3,3a,6,6a-tetrahydro-2H-cyclopenta [b]furan-2-one (2), along with two known metabolites, myrotheciumone A (1) and 4-oxo-4H-pyron-3-acetic acid (3) was isolated from the ethyl acetate extract of fermentation broth of Xylaria curta 92092022. The structures of these compounds were elucidated on the basis of spectroscopic methods (UV, IR, HRESITOFMS, 1D NMR, and 2D NMR). Compounds 1 and 2 showed moderate antibacterial and phytotoxic activities.
January 9, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28054079/gold-catalyzed-sequential-annulations-towards-3-4-fused-bi-tri-cyclic-furans-involving-a-3-2-2-cycloaddition
#8
Suna Liu, Pu Yang, Shiyong Peng, Chenghao Zhu, Shengyu Cao, Jian Li, Jiangtao Sun
A gold-catalyzed sequential annulation reaction to prepare 3,4-fused bicyclic furan compounds has been realized by employing 2-(1-alkynyl)-2-alken-1-ones and 1,3,5-triazines as the starting materials under mild reaction conditions. This protocol features multiple bond formation in a single operation with the incorporation of two nitrogen and two carbon atoms into the final products. A mechanistic investigation reveals that the sequential annulations involved an unprecedented stepwise [3+2+2]-cycloaddition.
January 5, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28052543/isolation-of-a-reactive-cyclopropane-intermediate-via-a-unique-catalyst-free-spontaneous-cyclopropanation-step-at-0-%C3%A2-c
#9
Holger Braunschweig, Rian Dewhurst, William Ewing, Marius Schäfer
A remarkably mild, catalyst-free cyclopropanation reaction is confirmed by low-temperature isolation of a fused bicyclic cyclopropane intermediate. This intermediate is one of two that were isolated and fully characterised in a three-step temperature-controllable reaction cascade.
January 4, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28051315/diamination-oxidative-cross-coupling-bicyclization-of-anilines-and-methyl-ketones-direct-i2-promoted-synthesis-of-1-2-fused-oxindoles
#10
Jingjing Zhang, Xia Wu, Qinghe Gao, Xiao Geng, Peng Zhao, Yan-Dong Wu, Anxin Wu
An I2-promoted domino bicyclization approach via multiple sequential C-H functionalization was serendipitously discovered for the synthesis of 1,2-fused oxindoles from methyl ketones and anilines. This approach was optimized, resulting in a concise and atom-economical approach for the one-pot construction of 1,2-fused oxindoles from methyl ketones and anilines rather than using preexisting indolin-3-ones or indoles. Mechanistic studies revealed that the key step involved an oxidative cross-coupling between in situ generated phenylglyoxal and α,α-diaminoketone...
January 4, 2017: Organic Letters
https://www.readbyqxmd.com/read/28049749/obesity-and-the-built-environment-at-different-urban-scales-examining-the-literature
#11
Andrea Garfinkel-Castro, Keuntae Kim, Shima Hamidi, Reid Ewing
The majority of people now live in an urban (or suburban) environment. The built (material) environment, its vehicular and pedestrian infrastructure, buildings, and public realm places, are the places used for working, living, and recreating. The environment currently favors and facilitates motorized vehicles generally, and private automobiles especially. The prioritization given to vehicles reduces opportunities for other, more active modes of travel such as walking and bicycling. Though the built environment cannot be said to directly affect human obesity, the built environment clearly has a relationship to obesity as a consequence of physical activity...
January 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/28049599/effective-orifice-area-during-exercise-in-bileaflet-mechanical-valve-prostheses
#12
Philippe B Bertrand, Matteo Pettinari, Hélène De Cannière, Herbert Gutermann, Christophe J P Smeets, David Verhaert, Robert A Dion, Pascal Verdonck, Pieter M Vandervoort
BACKGROUND: The aims of this study were to investigate the evolution of the transprosthetic pressure gradient and effective orifice area (EOA) during dynamic bicycle exercise in bileaflet mechanical heart valves and to explore the relationship with exercise capacity. METHODS: Patients with bileaflet aortic valve replacement (n = 23) and mitral valve replacement (MVR; n = 16) prospectively underwent symptom-limited supine bicycle exercise testing with Doppler echocardiography and respiratory gas analysis...
December 31, 2016: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28045164/bicyclic-enol-cyclocarbamates-inhibit-penicillin-binding-proteins
#13
Paul Dockerty, Jerre G Edens, Menno B Tol, Danae Morales Angeles, Arnau Domenech, Yun Liu, Anna K H Hirsch, Jan-Willem Veening, Dirk-Jan Scheffers, Martin D Witte
Natural products form attractive leads for the development of chemical probes and drugs. The antibacterial lipopeptide Brabantamide A contains an unusual enol cyclocarbamate and we used this scaffold as inspiration for the synthesis of a panel of enol cyclocarbamate containing compounds. By equipping the scaffold with different groups, we identified structural features that are essential for antibacterial activity. Some of the derivatives block incorporation of hydroxycoumarin carboxylic acid-amino d-alanine into the newly synthesized peptidoglycan...
January 3, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28043651/comparison-of-air-pollution-exposures-in-active-vs-passive-travel-modes-in-european-cities-a-quantitative-review
#14
REVIEW
Audrey de Nazelle, Olivier Bode, Juan Pablo Orjuela
BACKGROUND: Transport microenvironments tend to have higher air pollutant concentrations than other settings most people encounter in their daily lives. The choice of travel modes may affect significantly individuals' exposures; however such considerations are typically not accounted for in exposure assessment used in environmental health studies. In particular, with increasing interest in the promotion of active travel, health impact studies that attempt to estimate potential adverse consequences of potential increased pollutant inhalation during walking or cycling have emerged...
December 30, 2016: Environment International
https://www.readbyqxmd.com/read/28041898/-graded-cycling-test-with-talk-test-is-a-reliable-test-to-monitor-cardiovascular-fitness-in-patients-with-minor-stroke
#15
Rikke Steen Krawcyk, Anders Vinther, Nicolas Caesar Petersen, Christina Kruuse
BACKGROUND: Physical exercise is generally recommended as part of life style changes post stroke. Monitoring cardiovascular effects may help motivate patients for further exercise, and can be an instrument to assess intervention effects in clinical trials. In 1 of 4 stroke patients, the heart rate variability may challenge currently used cardiovascular monitoring. The Graded Cycling Test with Talk Test is a submaximal exercise test independent of heart rate variability, shown reliable for patients with cardiac disease...
December 29, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28039915/triad-of-constraints-in-bicycle-riding-in-children-with-cerebral-palsy
#16
David Sugden
No abstract text is available yet for this article.
December 31, 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28035784/enhancing-the-cell-permeability-and-metabolic-stability-of-peptidyl-drugs-by-reversible-bicyclization
#17
Ziqing Qian, Curran A Rhodes, Lucas C McCroskey, Jin Wen, George Appiah-Kubi, David J Wang, Denis C Guttridge, Dehua Pei
Therapeutic applications of peptides are currently limited by their proteolytic instability and impermeability to the cell membrane. A general, reversible bicyclization strategy is now reported to increase both the proteolytic stability and cell permeability of peptidyl drugs. A peptide drug is fused with a short cell-penetrating motif and converted into a conformationally constrained bicyclic structure through the formation of a pair of disulfide bonds. The resulting bicyclic peptide has greatly enhanced proteolytic stability as well as cell-permeability...
December 30, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/28033138/consequences-of-underestimating-impalement-bicycle-handlebar-injuries-in-children
#18
Carmen T Ramos-Irizarry, Shakeva Swain, Samantha Troncoso-Munoz, Malvina Duncan
Impalement bicycle handlebar trauma injuries are rare; however, on initial assessment, they have the potential of being underestimated. We reviewed our prospective trauma database of 3,894 patients for all bicycle injuries from January 2010 to May 2015. Isolated pedal bike injuries were reported in 2.6% (N = 101) of the patients who were admitted to the trauma service. Fifteen patients suffered direct handlebar trauma. Patients were grouped into blunt trauma (n = 12) and impalement trauma (n = 3). We examined gender, age, injury severity score (ISS), Glasgow Coma Scale score, use of protective devices, need for surgical intervention, need for intensive care (ICU), and hospital length of stay...
January 2017: Journal of Trauma Nursing: the Official Journal of the Society of Trauma Nurses
https://www.readbyqxmd.com/read/28032526/it-s-not-just-about-speed-reviewing-the-recumbent-bicycle-once-more
#19
Bernhard Wieser
Why did the recumbent bicycle never become a dominant design, despite the fact that it was faster than the safety bicycle on the racetrack? Hassaan Ahmed et al. argue in their recently published paper that the main reason for the marginalization of the recumbent bicycle was semiotic power deployed by the Union Cycliste Internationale (UCI). Here, I demonstrate that the authors drew their conclusions from an incomplete application of the Social Construction of Technology (SCOT) framework. Understanding the diffusion of alternative bicycle designs requires considering more than speed, and more than the UCI as a powerful actor...
December 1, 2016: Social Studies of Science
https://www.readbyqxmd.com/read/28032023/chiral-br%C3%A3-nsted-acid-catalyzed-enantioselective-%C3%AE-amidoalkylation-reactions-a-joint-experimental-and-predictive-study
#20
Eider Aranzamendi, Sonia Arrasate, Nuria Sotomayor, Humberto González-Díaz, Esther Lete
Enamides with a free NH group have been evaluated as nucleophiles in chiral Brønsted acid-catalyzed enantioselective α-amidoalkylation reactions of bicyclic hydroxylactams for the generation of quaternary stereocenters. A quantitative structure-reactivity relationship (QSRR) method has been developed to find a useful tool to rationalize the enantioselectivity in this and related processes and to orient the catalyst choice. This correlative perturbation theory (PT)-QSRR approach has been used to predict the effect of the structure of the substrate, nucleophile, and catalyst, as well as the experimental conditions, on the enantioselectivity...
December 2016: ChemistryOpen
keyword
keyword
4636
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"