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https://www.readbyqxmd.com/read/29224651/role-of-doppler-echocardiography-for-cardiac-output-assessment-in-fontan-patients
#1
Alexander Egbe, Arooj R Khan, Sana F Khan, Nandan S Anavekar, Sameh M Said, Philip M Young, Emmanuel Akintoye, William R Miranda, Mohamad N Al-Otaibi, Gruschen R Veldtman, Heidi M Connolly
BACKGROUND: To determine (1) correlation between Doppler stroke volume index (SVI) and cardiac magnetic resonance imaging (CMRI) SVI and (2) association between Doppler SVI and Fontan-associated diseases (FAD) and Fontan failure. METHODS: Review of Fontan patients who underwent same-day CMRI and transthoracic echocardiography (TTE), 2005 to 2015. We defined FAD as cardiac thrombus, protein-losing enteropathy, arrhythmia, and hospitalization for heart failure. Fontan failure was defined as Fontan conversion or revision, heart transplantation or listing, or death...
January 2018: American Heart Journal
https://www.readbyqxmd.com/read/29223466/long-term-pulmonary-and-cardiovascular-morbidities-of-neonatal-hyperoxia-exposure-in-mice
#2
Renuka T Menon, Amrit Kumar Shrestha, Corey L Reynolds, Roberto Barrios, Binoy Shivanna
Pulmonary hypertension (PH) frequently occurs in infants with bronchopulmonary dysplasia (BPD), causing increased mortality and right ventricular (RV) dysfunction that persists into adulthood. A first step in developing better therapeutic options is identifying and characterizing an appropriate animal model. Previously, we characterized the short-term morbidities of a model in which C57BL/6J wild-type (WT) mice were exposed to 70% O2 (hyperoxia) during the neonatal period. Here, we aimed to determine the long-term morbidities using lung morphometry, echocardiography (Echo), and cardiac magnetic resonance imaging (cMRI)...
December 7, 2017: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/29208679/the-time-trial-effect-of-timing-of-stem-cell-delivery-following-st-elevation-myocardial-infarction-on-the-recovery-of-global-and-regional-left-ventricular-function-final-2-year-analysis
#3
Jay H Traverse, Timothy D Henry, Carl J Pepine, James T Willerson, Atul R Chugh, Phillip C Yang, David Zhao, Stephen G Ellis, John R Forder, Emerson C Perin, Marc S Penn, Antonis K Hatzopoulos, Jeffrey W Chambers, Kenneth Baran, Ganesh Raveendran, Adrian P Gee, Doris A Taylor, Lem Moyé, Ray F Ebert, Robert D Simari
Rationale: The TIME trial was the first cell therapy trial sufficiently powered to determine if timing of cell delivery following ST-elevation myocardial infarction (STEMI) affects recovery of left ventricular (LV) function. Objective: To report the 2-year clinical and cardiac magnetic resonance imaging (cMRI) results and their modification by microvascular obstruction (MVO). Methods and Results: TIME was a randomized, double-blind, placebo-controlled trial comparing 150 million bone marrow mononuclear cells (BMC) vs...
December 5, 2017: Circulation Research
https://www.readbyqxmd.com/read/29201434/influence-of-longitudinal-position-on-the-evolution-of-steady-state-signal-in-cardiac-cine-balanced-steady-state-free-precession-imaging
#4
Tyler J Spear, Tori A Stromp, Steve W Leung, Moriel H Vandsburger
Background: Emerging quantitative cardiac magnetic resonance imaging (CMRI) techniques use cine balanced steady-state free precession (bSSFP) to measure myocardial signal intensity and probe underlying physiological parameters. This correlation assumes that steady-state is maintained uniformly throughout the heart in space and time. Purpose: To determine the effects of longitudinal cardiac motion and initial slice position on signal deviation in cine bSSFP imaging by comparing two-dimensional (2D) and three-dimensional (3D) acquisitions...
November 2017: Acta Radiologica Open
https://www.readbyqxmd.com/read/29193576/adaptive-servo-ventilation-for-central-sleep-apnoea-in-systolic-heart-failure-results-of-the-major-substudy-of-serve-hf
#5
Martin R Cowie, Holger Woehrle, Karl Wegscheider, Eik Vettorazzi, Susanne Lezius, Wolfgang Koenig, Frank Weidemann, Gillian Smith, Christiane Angermann, Marie-Pia d'Ortho, Erland Erdmann, Patrick Levy, Anita K Simonds, Virend K Somers, Faiez Zannad, Helmut Teschler
AIMS: The SERVE-HF trial investigated the impact of treating central sleep apnoea (CSA) with adaptive servo-ventilation (ASV) in patients with systolic heart failure. A preplanned substudy was conducted to provide insight into mechanistic changes underlying the observed effects of ASV, including assessment of changes in left ventricular function, ventricular remodelling, and cardiac, renal and inflammatory biomarkers. METHODS AND RESULTS: In a subset of the 1325 randomised patients, echocardiography, cardiac magnetic resonance imaging (cMRI) and biomarker analysis were performed at baseline, and 3 and 12 months...
November 30, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29146416/fulminant-adrenergic-myocarditis-complicated-by-pulmonary-edema-cardiogenic-shock-and-cardiac-arrest
#6
Pawel Rostoff, Bohdan Nessler, Patrycja Pikul, Karolina Golinska-Grzybala, Tomasz Miszalski-Jamka, Jadwiga Nessler
Adrenergic myocarditis is an uncommon presentation of pheochromocytoma and extremely rare cause of de novo acute heart failure (AHF). We present a case of a 31-year-old Caucasian woman with a history of hypertension and recurrent occipital headaches who was admitted to the emergency department due to severe de novo AHF presenting as pulmonary edema and cardiogenic shock. During the hospital admission the patient experienced asystolic cardiac arrest and was successfully resuscitated, intubated, and mechanically ventilated...
November 10, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29121072/accuracy-of-echocardiographic-indices-for-serial-monitoring-of-right-ventricular-systolic-function-in-patients-with-precapillary-pulmonary-hypertension
#7
Takahiro Sato, Ichizo Tsujino, Hiroshi Ohira, Noriko Oyama-Manabe, Yoichi M Ito, Chisa Takashina, Taku Watanabe, Masaharu Nishimura
BACKGROUND: Serial assessment of right ventricular ejection fraction (RVEF) predicts the clinical outcome of patients with pulmonary hypertension (PH). Cardiac magnetic resonance imaging (CMRI) enables RVEF monitoring, but its applicability is limited in clinical practice. This study aimed to examine the correlation between changes in CMRI-derived RVEF with those in echocardiographic indices in patients with precapillary PH. METHODS: CMRI and echocardiographic indices of RV systolic function were evaluated at baseline and follow-up in 54 consecutive patients with precapillary PH (pulmonary arterial hypertension (PAH), n = 23; non-PAH, n = 31)...
2017: PloS One
https://www.readbyqxmd.com/read/29109956/incidental-extracardiac-findings-and-their-characterization-on-cardiac-mri
#8
Matteo Gravina, Luca Pio Stoppino, Grazia Casavecchia, Angelo Pio Moffa, Roberta Vinci, Natale Daniele Brunetti, Matteo Di Biase, Luca Macarini
Background: Cardiac magnetic resonance imaging (cMRI) has recently emerged as a new noninvasive imaging modality that offers superior structural and functional assessment of the heart. cMRI benefits from a large field of view but, consequently, may capture incidental extracardiac findings (IEFs). We aimed to evaluate the frequency and significance of IEFs reported from clinically indicated cMRI scans. Methods: 742 consecutive patients (402 males and 340 females) referred to the Cardiac Magnetic Resonance Center of our University Hospital between January 2015 and December 2016 for clinically indicated cMRI were retrospectively enrolled for the evaluation of IEF prevalence and relevance...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29090491/clinical-safety-and-performance-of-a-mri-conditional-pacing-system-in-patients-undergoing-cardiac-mri
#9
Chi Keong Ching, Rabindra Nath Chakraborty, Tarlochan Singh Kler, Satchana Pumprueg, Tachapong Ngarmukos, Joseph Yat Sun Chan, Sumit Anand, Rakesh Yadav, Surapun Sitthisook, Ka Wing Yim, Rakesh K Jaswal, Kartikeya Bhargava
BACKGROUND: Utilization of cardiac Magnetic Resonance Imaging (cMRI) as an imaging modality in clinical practice is rapidly increasing. More evidence from randomized studies establishing clinical safety and performance of pacing systems in patients undergoing a cMRI scan is needed. OBJECTIVES: The purpose of this prospective, multi-center, randomized study was to demonstrate safety and efficacy of the Accent MRIۛ conditional pacing systems in patients undergoing cMRI scan...
November 1, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29081724/role-of-stress-cardiac-magnetic-resonance-imaging-in-women-with-suspected-ischemia-but-no-obstructive-coronary-artery-disease
#10
Sawan Jalnapurkar, Parham Zarrini, Puja K Mehta, Louise E J Thomson, Megha Agarwal, Bruce A Samuels, Chrisandra L Shufelt, Jo-Ann Eastwood, Daniel Berman, Noel Bairey Merz, Margo B Minissian
OBJECTIVE: Signs and symptoms of ischemia but no obstructive coronary artery disease (CAD) is often a diagnostic dilemma in women. The use of stress cardiac magnetic resonance imaging (CMRI) for advanced diagnostic assessment in these patients is a non-ionizing radiation option, but the diagnostic utility in this population is unknown. We examined the diagnostic role of stress CMRI in our patient population of these women. METHODS: We analyzed 113 consecutive female patients from 2/2006-11/2007 who had prior cardiac evaluations for signs and symptoms of ischemia but no obstructive CAD who underwent stress CMRI, which included anatomic, functional, adenosine stress perfusion and delayed enhancement imaging...
September 2017: Journal of Radiology Nursing
https://www.readbyqxmd.com/read/29071373/longitudinal-myocardial-deformation-does-not-predict-single-ventricle-ejection-fraction-assessed-by-cardiac-magnetic-resonance-imaging-in-children-with-a-total-cavopulmonary-connection
#11
L P Koopman, L M Geerdink, S S M Bossers, N Duppen, I M Kuipers, A D Ten Harkel, G van Iperen, G Weijers, C de Korte, W A Helbing, L Kapusta
Survival of children with single ventricle heart defects after the total cavopulmonary connection (TCPC) has improved, but impaired cardiac function remains a major cause of morbidity and mortality. Cardiac magnetic resonance imaging (cMRI) is the gold standard in assessing single ventricle volume and function, but high costs and limited availability hamper its routine use. A cheaper and more available alternative is echocardiography. Myocardial function can be studied in more detail using speckle tracking echocardiography (STE)...
October 25, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29054563/early-diastolic-septal-movement-in-patients-with-myocarditis
#12
M Jeserich, B Merkely, P Schlosser, S Kimmel, G Pavlik, J Biermann
AIM: To evaluate early diastolic septal relaxation as a parameter in the diagnostic workup via cardiovascular magnetic resonance imaging (CMRI) in patients with myocarditis. MATERIALS AND METHODS: Early diastolic septal movement was evaluated (EDS) prospectively via frame-by-frame analysis in 255 consecutive patients with presenting signs of myocarditis and in 64 controls matched 4:1 for gender and age. ECG-triggered, T2-weighted, fast spin echo triple inversion recovery sequences and late gadolinium enhancement were obtained, as well as left ventricular (LV) function and dimensions in patients and controls...
October 17, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29035464/galectin-3-reflects-left-atrial-function-being-assessed-by-cardiac-magnetic-resonance-imaging
#13
Seung-Hyun Kim, Michael Behnes, Michele Natale, Sonja Hamed, Julia Hoffmann, Ursula Hoffmann, Johannes Budjan, Siegfried Lang, Martin Borggrefe, Theano Papavassiliu, Thomas Bertsch, Ibrahim Akin
BACKGROUND: This study aims to evaluate the association between galectin-3 and left atrial function (LAF) in patients undergoing cMRI. METHODS: Patients undergoing cMRI were prospectively enrolled. Right ventricular dysfunction (< 50%) was excluded. Blood samples for biomarker measurements of galectin-3 and NT-proBNP were collected at the time of cMRI examination. RESULTS: A total of 84 patients were included. Median LVEF was 59% (IQR 51 - 64%)...
October 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/29024757/correlation-between-admission-hyperglycemia-and-area-at-risk-and-infarct-size-quantified-by-cmr-in-acute-myocardial-infarction
#14
Stella Pak, Yan Yatsynovich, John-Phillip Markovic
AIMS: The goal was to compare the size of myocardial infarct detected on CMRI between patients with and without admission hyperglycemia after acute myocardial infarction. METHODS: Studies were located from database searching on MEDLINE, EMBASE, and CINAHL. Systematic review was conducted by two independent reviewers. Microvascular obstruction and late gadolinium enhancement were pooled from available studies to calculate the standardized mean difference (SMD) in post-MI infarct size between patients with and without hyperglycemia in admission...
October 9, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29018942/evaluation-of-an-abbreviated-screening-mri-protocol-for-patients-at-risk-for-hepatocellular-carcinoma
#15
Jennifer Y Lee, Eugene J Huo, Stefanie Weinstein, Charmaine Santos, Alexander Monto, Carlos U Corvera, Judy Yee, Thomas A Hope
PURPOSE: In this study, we compare an abbreviated screening MRI protocol (aMRI), utilizing only dynamic contrast-enhanced images, to a conventional liver MRI (cMRI) for the characterization of observations in at-risk patients. MATERIALS AND METHODS: 164 consecutive HCC screening MRIs were retrospectively analyzed. Two sets of de-identified image sets were created: one with all acquired sequences including T2- and diffusion-weighted sequences (cMRI), and one with only T1-weighted precontrast and dynamic post-contrast images utilizing an extracellular gadolinium contrast agent (aMRI)...
October 10, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28986695/absence-of-dna-double-strand-breaks-in-human-peripheral-blood-mononuclear-cells-after-3-tesla-magnetic-resonance-imaging-assessed-by-%C3%AE-h2ax-flow-cytometry
#16
Martin Fasshauer, Thomas Krüwel, Antonia Zapf, Vera C Stahnke, Margret Rave-Fränk, Wieland Staab, Jan M Sohns, Michael Steinmetz, Christina Unterberg-Buchwald, Andreas Schuster, Christian Ritter, Joachim Lotz
OBJECTIVES: Magnetic resonance imaging (MRI) is regarded as a non-harming and non-invasive imaging modality with high tissue contrast and almost no side effects. Compared to other cross-sectional imaging modalities, MRI does not use ionising radiation. Recently, however, strong magnetic fields as applied in clinical MRI scanners have been suspected to induce DNA double-strand breaks in human lymphocytes. METHODS: In this study we investigated the impact of 3-T cardiac MRI examinations on the induction of DNA double-strand breaks in peripheral mononuclear cells by γH2AX staining and flow cytometry analysis...
October 6, 2017: European Radiology
https://www.readbyqxmd.com/read/28986271/the-subclinical-cardiomyopathy-of-friedreich-s-ataxia-in-a-pediatric-population
#17
Jonathan F Plehn, Keren Hasbani, Inez Ernst, Kenneth D Horton, Bart E Drinkard, Nicholas A Di Prospero
BACKGROUND: Identification of a subclinical cardiomyopathy in a pediatric patients with Friedreich's ataxia (FA) has not been well-described. METHODS: We performed echocardiography (echo), cardiac magnetic resonance imaging (cMRI) and neurologic assessment in a cross-sectional analysis of 48 genetically-confirmed FA subjects aged 9-17 years with moderate neurologic impairment but without a cardiovascular history. Echo and cMRI-determined left ventricular mass were indexed to height in g/m2...
October 3, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28978339/high-sensitivity-troponin-t-and-i-reflect-mitral-annular-plane-systolic-excursion-being-assessed-by-cardiac-magnetic-resonance-imaging
#18
Michèle Natale, Michael Behnes, Seung-Hyun Kim, Julia Hoffmann, Nadine Reckord, Ursula Hoffmann, Johannes Budjan, Siegfried Lang, Martin Borggrefe, Theano Papavassiliu, Thomas Bertsch, Ibrahim Akin
PURPOSE: This study aims to evaluate the association between high sensitivity troponins (hsTn) and mitral annular plane systolic excursion (MAPSE) in patients undergoing cardiac magnetic resonance imaging (cMRI). METHODS: Patients undergoing cMRI were prospectively enrolled. Patients with right ventricular dysfunction (< 50%) were excluded. Blood samples for measurements of hsTn and amino-terminal pro-brain natriuretic peptide (NT-proBNP) were collected at the time of cMRI...
October 4, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/28947308/relation-of-left-atrial-size-cardiac-morphology-and-clinical-outcome-in-asymptomatic-aortic-stenosis
#19
Nicolaj Lyhne Christensen, Jordi Sanchez Dahl, Rasmus Carter-Storch, Rine Bakkestrøm, Redi Pecini, Flemming Hald Steffensen, Eva Vad Søndergaard, Lars Melgaard Videbæk, Jacob Eifer Møller
Left atrial (LA) dilation in asymptomatic severe aortic stenosis (AS) may be an indicator of advanced disease. We aimed to investigate the association between LA volume index and left ventricular (LV) morphology assessed with cardiac magnetic resonance imaging (cMRI), and to assess the association with cardiac events. Ninety-two asymptomatic patients with aortic valve area <1 cm(2), aortic peak jet velocity >3.5 m/s, and ejection fraction ≥50% were prospectively enrolled and divided according to echocardiographic-derived LA volume index  <35 ml/m(2)...
November 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28900462/comparison-of-the-therapeutic-effects-of-acupuncture-at-pc6-and-st36-for-chronic-myocardial-ischemia
#20
Li Shi, Jiliang Fang, Jiping Zhao, Guiyong Liu, Qing Zhao, Jinling Zhang, Jinzhao Zhang, Bing Zhu, Fanrong Liang, Peijing Rong
We aimed to compare the differences of the effects on chronic myocardial ischemia (MI) of acupuncture at PC6 and ST36. The chronic MI model of minipigs was created by implanting an Ameroid constrictor on the left anterior descending coronary artery (LAD) and then two weeks' acupuncture was stimulated at PC6 or ST36, respectively. The results showed that both acupoints' stimulation decreased the serous cardiac troponin T (cTnT) and ischemia modified albumin (IMA) significantly and improved the ischemic ECG changes...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
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