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https://www.readbyqxmd.com/read/29657146/absence-of-fibrosis-and-inflammation-by-cardiac-magnetic-resonance-imaging-in-rheumatoid-arthritis-patients-with-low-to-moderate-disease-activity
#1
William Bradham, Michelle J Ormseth, Comfort Elumogo, Srikanth Palanisamy, Chia-Ying Liu, Mark A Lawson, Jonathan H Soslow, Nadine Kawel-Boehm, David A Bluemke, C Michael Stein
OBJECTIVE: The prevalence of heart failure is increased 2-fold in patients with rheumatoid arthritis (RA); this is not explained by ischemic heart disease or other risk factors for heart failure. We hypothesized that in patients with RA without known heart disease, cardiac magnetic resonance imaging (cMRI) would detect altered cardiac structure, function, and fibrosis. METHODS: We performed 1.5-T cMRI in 59 patients with RA and 56 controls frequency-matched for age, race, and sex, and compared cMRI indices of structure, function, and fibrosis [late gadolinium enhancement (LGE), native T1 mapping, and extracellular volume (ECV)] using Mann-Whitney U tests and linear regression, adjusting for age, race, and sex...
April 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29520572/assessment-of-left-ventricular-ejection-fraction-with-cardiofocal-collimators-comparison-between-iq-spect-planar-equilibrium-radionuclide-angiography-and-cardiac-magnetic-resonance
#2
Matthieu Pelletier-Galarneau, Vincent Finnerty, Stephanie Tan, Sebastien Authier, Jean Gregoire, Francois Harel
BACKGROUND: IQ-SPECT has been shown to significantly reduce acquisition time and administered dose while preserving image quality in myocardial perfusion imaging. Whether IQ-SPECT provides accurate left ventricular ejection fractions (LVEF) with gated blood pool SPECT (GBPS) remains unknown. METHODS: Sixty patients underwent IQ-SPECT GBPS and planar imaging. Among those patients, 11 underwent both cMRI and GBPS. GBPS LVEF, LVEDV, and LVESV were calculated using 2 validated software; QBS (Cedars-Sinai Medical Center, Los Angeles, USA) and MHI (Montreal Heart Institute, Montreal, Canada)...
March 8, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29519957/analysis-of-chronic-aortic-regurgitation-by-2d-and-3d-echocardiography-and-cardiac-mri
#3
Stephan Stoebe, Michael Metze, Daniel Jurisch, Bhupendar Tayal, Kilian Solty, Ulrich Laufs, Dietrich Pfeiffer, Andreas Hagendorff
PURPOSE: The study compares the feasibility of the quantitative volumetric and semi-quantitative approach for quantification of chronic aortic regurgitation (AR) using different imaging modalities. METHODS: left ventricular (LV) volumes, regurgitant volumes (RVol) and regurgitant fractions (RF) were assessed retrospectively by 2D, 3D echocardiography and cMRI in 55 chronic AR patients. Semi-quantitative parameters were assessed by 2D echocardiography. RESULTS: 22 (40%) patients had mild, 25 (46%) moderate and 8 (14%) severe AR...
March 8, 2018: Echo Research and Practice
https://www.readbyqxmd.com/read/29498104/cardio-hepatic-risk-assessment-by-cmr-imaging-in-liver-transplant-candidates
#4
Sahadev T Reddy, Ngoc L Thai, Jose Oliva, Kusum B Tom, Michael K Dishart, Mark Doyle, June A Yamrozik, Ronald B Williams, Moneal Shah, Adil Wani, Anil Singh, Rishi Maheswary, Robert W W Biederman
BACKGROUND: The preoperative workup of orthotopic liver transplantation (OLT) patients is practically complex given the need for multiple imaging modalities. We recently demonstrated in our proof-of-concept study the value of a one-stop-shop approach using cardiovascular MRI (CMR) to address this complex problem. However, this approach requires further validation in a larger cohort, as detection of hepatocellular carcinoma (HCC) as well as cardiovascular risk assessment is critically important in these patients...
March 2, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29490637/study-protocol-for-a-randomised-controlled-trial-of-exercise-training-in-pulmonary-hypertension-extra_ph
#5
Norman R Morris, Menaka Louis, Wendy Strugnell, Julie Harris, Aaron Lin, John Feenstra, Helen Seale
BACKGROUND: Exercise training is an integral component of evidence-based management programs for many chronic cardiac and respiratory conditions. Despite this, there are limited high-quality studies available on the significance of exercise training in pulmonary hypertension (PH). The aim of this study is to evaluate the short and long-term effectiveness of exercise training in PH patients in terms of exercise capacity, quality of life, cardiac function and disease progression. METHODS: This randomized control trial will aim to recruit 50 medically stable PH patients categorised as New York Heart Association functional classification II-III...
March 1, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29396582/comparative-noninvasive-measurement-of-cardiac-output-based-on-the-inert-gas-rebreathing-method-innocor%C3%A2-and-mri-in-patients-with-univentricular-hearts
#6
Miriam Kuhn, Andreas Hornung, Heidi Ulmer, Christian Schlensak, Michael Hofbeck, Gesa Wiegand
There are many complex cardiac malformations that are characterized by a functionally univentricular physiology. Staged surgical repair according to the Fontan principle separates the systemic and pulmonary circulations by connecting the systemic venous return to the pulmonary arteries. However, long-term follow-up studies demonstrate a gradual deterioration of cardiac function, particularly from the second or third decade. Noninvasive evaluation of the cardiac function is, therefore, important in the follow-up of these patients...
February 3, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29391146/ischemic-mitral-regurgitation-abnormal-strain-overestimates-non-viable-myocardium
#7
Ashley E Morgan, Yue Zhang, Mehrzad Tartibi, Samantha Goldburg, Jiwon J Kim, Thanh D Nguyen, Julius Guccione, Liang Ge, Jonathan W Weinsaft, Mark B Ratcliffe
BACKGROUND: Therapy for moderate ischemic mitral regurgitation (IMR) remains unclear. Determination of myocardial viability, a necessary pre-requisite for an improvement in regional contractility, is a likely key factor in determining response to revascularization alone. Myocardial strain has been proposed as a viability measure but has not been compared to late gadolinium enhancement (LGE) cardiac (c)MRI. We hypothesized that abnormal strain overestimates non-viable LV segments measured using LGE and that ischemia and mechanical tethering by adjacent transmural myocardial infarction (TMI) also decreases strain in viable segments...
January 29, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29387425/comparison-of-tricuspid-annular-plane-systolic-excursion-with-fractional-area-change-for-the-evaluation-of-right-ventricular-systolic-function-a-meta-analysis
#8
Justin Z Lee, See-Wei Low, Ahmed K Pasha, Carol L Howe, Kwan S Lee, Prakash G Suryanarayana
Background: Accurate determination of right ventricular ejection fraction (RVEF) is challenging because of the unique geometry of the right ventricle. Tricuspidannular plane systolic excursion (TAPSE) and fractional area change (FAC) are commonly used echocardiographic quantitative estimates of RV function. Cardiac MRI (CMRI) has emerged as the gold standard for assessment of RVEF. We sought to summarise the available data on correlation of TAPSE and FAC with CMRI-derived RVEF and to compare their accuracy...
2018: Open Heart
https://www.readbyqxmd.com/read/29339703/a-case-of-asymptomatic-large-aortopulmonary-window-in-an-adult-role-of-cardiac-ct-cmri-and-3d-printing-technology
#9
Aniketh Vijay Balegadde, Vikrant Vijan, Rajesh Thachathodiyl, Mahesh Kappanayil
No abstract text is available yet for this article.
January 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29332032/value-of-conventional-mri-and-diffusion-tensor-imaging-parameters-in-predicting-surgical-outcome-in-patients-with-degenerative-cervical-myelopathy
#10
Canghai Shen, Haiwei Xu, Baoshan Xu, Xiaoguang Zhang, Xiaofeng Li, Qiang Yang, Xinlong Ma
BACKGROUND: In addition to conventional magnetic resonance imaging (cMRI), diffusion tensor imaging (DTI) has been investigated as a potential diagnostic and prognostic tool for patients with degenerative cervical myelopathy (DCM). OBJECTIVE: To assess the efficacy of cMRI and DTI parameters in prediction of surgical outcome in DCM patients. METHODS: One hundred and forty-two patients with DCM who underwent presurgical cMRI and DTI of the cervical spine were included...
December 29, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29320524/patients-with-primary-biliary-cholangitis-and-fatigue-present-with-depressive-symptoms-and-selected-cognitive-deficits-but-with-normal-attention-performance-and-brain-structure
#11
Roman Zenouzi, Janina von der Gablentz, Marcus Heldmann, Martin Göttlich, Christina Weiler-Normann, Marcial Sebode, Hanno Ehlken, Johannes Hartl, Anja Fellbrich, Susanne Siemonsen, Christoph Schramm, Thomas F Münte, Ansgar W Lohse
BACKGROUND: In primary biliary cholangitis (PBC) fatigue is a major clinical challenge of unknown etiology. By demonstrating that fatigue in PBC is associated with an impaired cognitive performance, previous studies have pointed out the possibility of brain abnormalities underlying fatigue in PBC. Whether structural brain changes are present in PBC patients with fatigue, however, is unclear. To evaluate the role of structural brain abnormalities in PBC patients severely affected from fatigue we, therefore, performed a case-control cerebral magnetic resonance imaging (cMRI) study and correlated changes of white and grey brain matter with the cognitive and attention performance...
2018: PloS One
https://www.readbyqxmd.com/read/29306483/left-ventricular-volume-time-relation-in-patients-with-heart-failure-with-preserved-ejection-fraction
#12
Michinari Hieda, Joshua Parker, Tanya Rajabi, Naoki Fujimoto, Paul S Bhella, Anand Prasad, Jeffrey L Hastings, Satyam Sarma, Benjamin D Levine
Elevated left ventricular (LV) filling pressures are commonly reported in patients with heart failure with preserved ejection fraction (HFpEF) and are associated with impaired relaxation in diastole. Relaxation has been assessed by Doppler, but the methods for doing so are indirect and heavily influenced by loading conditions. The aim of this study is to assess LV volume-time relation in patients with HFpEF, when correcting for left atrial driving pressure and chamber size, using cardiac magnetic resonance imaging (cMRI)...
March 1, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29259047/neuropsychiatric-lupus-or-not-cerebral-hypoperfusion-by-perfusion-weighted-mri-in-normal-appearing-white-matter-in-primary-neuropsychiatric-lupus-erythematosus
#13
Efrosini Papadaki, Antonis Fanouriakis, Eleftherios Kavroulakis, Dimitra Karageorgou, Prodromos Sidiropoulos, George Bertsias, Panagiotis Simos, Dimitrios T Boumpas
OBJECTIVES: Cerebral perfusion abnormalities have been reported in systemic lupus erythematosus (SLE) but their value in distinguishing lupus from non-lupus-related neuropsychiatric events remains elusive. We examined whether dynamic susceptibility contrast-enhanced perfusion MRI (DSC-MRI), a minimally invasive and widely available method of cerebral perfusion assessment, may assist neuropsychiatric SLE (NPSLE) diagnosis. METHODS: In total, 76patients with SLE (37 primary NPSLE, 16 secondary NPSLE, 23 non-NPSLE) and 31 healthy controls underwent conventional MRI (cMRI) and DSC-MRI...
March 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29224651/role-of-doppler-echocardiography-for-cardiac-output-assessment-in-fontan-patients
#14
Alexander Egbe, Arooj R Khan, Sana F Khan, Nandan S Anavekar, Sameh M Said, Philip M Young, Emmanuel Akintoye, William R Miranda, Mohamad N Al-Otaibi, Gruschen R Veldtman, Heidi M Connolly
BACKGROUND: To determine (1) correlation between Doppler stroke volume index (SVI) and cardiac magnetic resonance imaging (CMRI) SVI and (2) association between Doppler SVI and Fontan-associated diseases (FAD) and Fontan failure. METHODS: Review of Fontan patients who underwent same-day CMRI and transthoracic echocardiography (TTE), 2005 to 2015. We defined FAD as cardiac thrombus, protein-losing enteropathy, arrhythmia, and hospitalization for heart failure. Fontan failure was defined as Fontan conversion or revision, heart transplantation or listing, or death...
January 2018: American Heart Journal
https://www.readbyqxmd.com/read/29223466/long-term-pulmonary-and-cardiovascular-morbidities-of-neonatal-hyperoxia-exposure-in-mice
#15
Renuka T Menon, Amrit Kumar Shrestha, Corey L Reynolds, Roberto Barrios, Binoy Shivanna
Pulmonary hypertension (PH) frequently occurs in infants with bronchopulmonary dysplasia (BPD), causing increased mortality and right ventricular (RV) dysfunction that persists into adulthood. A first step in developing better therapeutic options is identifying and characterizing an appropriate animal model. Previously, we characterized the short-term morbidities of a model in which C57BL/6J wild-type (WT) mice were exposed to 70% O2 (hyperoxia) during the neonatal period. Here, we aimed to determine the long-term morbidities using lung morphometry, echocardiography (Echo), and cardiac magnetic resonance imaging (cMRI)...
January 2018: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/29208679/time-trial-effect-of-timing-of-stem-cell-delivery-following-st-elevation-myocardial-infarction-on-the-recovery-of-global-and-regional-left-ventricular-function-final-2-year-analysis
#16
Jay H Traverse, Timothy D Henry, Carl J Pepine, James T Willerson, Atul Chugh, Phillip C Yang, David X M Zhao, Stephen G Ellis, John R Forder, Emerson C Perin, Marc S Penn, Antonis K Hatzopoulos, Jeffrey C Chambers, Kenneth W Baran, Ganesh Raveendran, Adrian P Gee, Doris A Taylor, Lem Moyé, Ray F Ebert, Robert D Simari
RATIONALE: The TIME trial (Timing in Myocardial Infarction Evaluation) was the first cell therapy trial sufficiently powered to determine if timing of cell delivery after ST-segment-elevation myocardial infarction affects recovery of left ventricular (LV) function. OBJECTIVE: To report the 2-year clinical and cardiac magnetic resonance imaging results and their modification by microvascular obstruction. METHODS AND RESULTS: TIME was a randomized, double-blind, placebo-controlled trial comparing 150 million bone marrow mononuclear cells versus placebo in 120 patients with anterior ST-segment-elevation myocardial infarctions resulting in LV dysfunction...
February 2, 2018: Circulation Research
https://www.readbyqxmd.com/read/29201434/influence-of-longitudinal-position-on-the-evolution-of-steady-state-signal-in-cardiac-cine-balanced-steady-state-free-precession-imaging
#17
Tyler J Spear, Tori A Stromp, Steve W Leung, Moriel H Vandsburger
Background: Emerging quantitative cardiac magnetic resonance imaging (CMRI) techniques use cine balanced steady-state free precession (bSSFP) to measure myocardial signal intensity and probe underlying physiological parameters. This correlation assumes that steady-state is maintained uniformly throughout the heart in space and time. Purpose: To determine the effects of longitudinal cardiac motion and initial slice position on signal deviation in cine bSSFP imaging by comparing two-dimensional (2D) and three-dimensional (3D) acquisitions...
November 2017: Acta Radiologica Open
https://www.readbyqxmd.com/read/29193576/adaptive-servo-ventilation-for-central-sleep-apnoea-in-systolic-heart-failure-results-of-the-major-substudy-of-serve-hf
#18
Martin R Cowie, Holger Woehrle, Karl Wegscheider, Eik Vettorazzi, Susanne Lezius, Wolfgang Koenig, Frank Weidemann, Gillian Smith, Christiane Angermann, Marie-Pia d'Ortho, Erland Erdmann, Patrick Levy, Anita K Simonds, Virend K Somers, Faiez Zannad, Helmut Teschler
AIMS: The SERVE-HF trial investigated the impact of treating central sleep apnoea (CSA) with adaptive servo-ventilation (ASV) in patients with systolic heart failure. A preplanned substudy was conducted to provide insight into mechanistic changes underlying the observed effects of ASV, including assessment of changes in left ventricular function, ventricular remodelling, and cardiac, renal and inflammatory biomarkers. METHODS AND RESULTS: In a subset of the 1325 randomised patients, echocardiography, cardiac magnetic resonance imaging (cMRI) and biomarker analysis were performed at baseline, and 3 and 12 months...
March 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29146416/fulminant-adrenergic-myocarditis-complicated-by-pulmonary-edema-cardiogenic-shock-and-cardiac-arrest
#19
Pawel Rostoff, Bohdan Nessler, Patrycja Pikul, Karolina Golinska-Grzybala, Tomasz Miszalski-Jamka, Jadwiga Nessler
Adrenergic myocarditis is an uncommon presentation of pheochromocytoma and extremely rare cause of de novo acute heart failure (AHF). We present a case of a 31-year-old Caucasian woman with a history of hypertension and recurrent occipital headaches who was admitted to the emergency department due to severe de novo AHF presenting as pulmonary edema and cardiogenic shock. During the hospital admission the patient experienced asystolic cardiac arrest and was successfully resuscitated, intubated, and mechanically ventilated...
November 10, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29121072/accuracy-of-echocardiographic-indices-for-serial-monitoring-of-right-ventricular-systolic-function-in-patients-with-precapillary-pulmonary-hypertension
#20
Takahiro Sato, Ichizo Tsujino, Hiroshi Ohira, Noriko Oyama-Manabe, Yoichi M Ito, Chisa Takashina, Taku Watanabe, Masaharu Nishimura
BACKGROUND: Serial assessment of right ventricular ejection fraction (RVEF) predicts the clinical outcome of patients with pulmonary hypertension (PH). Cardiac magnetic resonance imaging (CMRI) enables RVEF monitoring, but its applicability is limited in clinical practice. This study aimed to examine the correlation between changes in CMRI-derived RVEF with those in echocardiographic indices in patients with precapillary PH. METHODS: CMRI and echocardiographic indices of RV systolic function were evaluated at baseline and follow-up in 54 consecutive patients with precapillary PH (pulmonary arterial hypertension (PAH), n = 23; non-PAH, n = 31)...
2017: PloS One
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