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https://www.readbyqxmd.com/read/29793012/endovascular-repair-of-a-penetrating-aortic-ulcer-with-a-custom-made-relay-stent-graft-featuring-a-single-celiac-trunk-fenestration-and-a-superior-mesenteric-artery-scallop
#1
G Natalicchio, A Biello, G Castriotta, M G C La Marca, G Sorino, M Salcuni
We report the case of a 70-year-old man with an asymptomatic, fast-growing, paraceliac penetrating aortic ulcer (PAU). Guidelines recommend endovascular repair if an asymptomatic PAU shows a mean growth rate ≥5 mm per year: this patient's maximum aortic diameter was 47 mm but had increased 10 mm in the previous year. The very short sealing zones required a custom-made stent-graft. A custom-made Relay stent-graft with a single celiac trunk fenestration, a superior mesenteric artery (SMA) scallop measured according to SMA ostium size, an uncovered distal stent, and 6-mm tapering was used with technical and clinical success...
May 21, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29790721/techniques-and-outcomes-of-secondary-endovascular-repair-for-post-dissection-taa-taaa
#2
Pablo Marques De Marino, Kyriakos Oikonomou, Eric L Verhoeven, Athanasios Katsargyris
Post-dissection aortic aneurysms (PDAA) affect 20-40% of patients with aortic dissection. Open repair remains the first line therapy of PDAA, but is still associated with high mortality and morbidity rates. Endovascular repair is increasingly being used as a less invasive treatment option. Thoracic endovascular aneurysm repair (TEVAR) covering only the proximal entry tear has proven to be insufficient in most patients with chronic PDAA and has a limited role only for PDAA with distal sealing zone in the thoracic aorta...
May 23, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29788188/importance-of-fenestration-size-for-definitive-treatment-of-a-quadrigeminal-arachnoid-cyst-endoscopic-inspection-of-the-cyst-and-surrounding-anatomy-2-dimensional-operative-video
#3
François Lechanoine, Pietro Spennato, Claudio Ruggiero, Giuseppe Cinalli
Arachnoid cysts are fluid-filled sacs, located between the brain or spinal cord and the arachnoid membrane. Their prevalence in children is between 1% and 3%. Quadrigeminal arachnoid cysts represent 1% to 10% of them and are often associated with hydrocephalus, mostly by an obstructive mechanism, explained by compression of the tectum of the midbrain. When an indication for treatment is retained, 3 surgical options are available: microsurgical excision/fenestration, endoscopic fenestration, and shunt placement...
May 18, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29785590/clinical-application-of-a-minimally-invasive-cement-augmentable-schanz-screw-rod-system-to-treat-pelvic-ring-fractures
#4
Paul Schmitz, Florian Baumann, Yves P Acklin, Boyko Gueorguiev, Michael Nerlich, Stephan Grechenig, Michael Bernd Müller
PURPOSE: The purpose of this study is to analyze the results using the USS fracture MIS system (DePuy Synthes) to treat instable pelvic ring fractures. As its outstanding feature, it is the only Schanz screw and rod system at present that combines angular stability, perforation/fenestration of the screws for cement-augmentation, a variable screw length, and a large screw diameter. MATERIALS AND METHODS: Retrospective investigation of 134 pelvic ring fractures treated in 2012-2013...
May 21, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29784569/use-of-the-zenith-fenestrated-platform-to-rescue-failing-endovascular-and-open-aortic-reconstructions-is-safe-and-technically-feasible
#5
S Keisin Wang, Natalie A Drucker, Alan P Sawchuk, Gary W Lemmon, Michael C Dalsing, Raghu L Motaganahalli, Michael P Murphy, Andres Fajardo
OBJECTIVE: Proximal neck dilation is a serious long-term complication directly causing the failure of endovascular aneurysm repair (EVAR) and open surgical repair (OSR) of abdominal aortic aneurysms. However, the implantation of a fenestrated device presents the opportunity for proximal extension of the aortic reconstruction into a healthy segment while maintaining patency of the visceral vessels. The objective of this investigation was to report perioperative and follow-up outcomes using the Zenith Fenestrated (ZFEN; Cook Medical, Bloomington, Ind) aortic stent system in salvaging previous aortic repairs undergoing type IA endoleak or aneurysmal degeneration of the proximal neck...
May 18, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29783002/a-stepwise-approach-to-laparoscopic-enucleation-and-excision-of-retroperitoneal-cysts
#6
Haider Jan, Tina Kapoor, Vishalli Ghai
STUDY OBJECTIVE: Technical video demonstrating a step by step approach to laparoscopic enucleation and excision of retroperitoneal cysts. DESIGN: Technical video (Canadian Task Force classification III). SETTING: Benign Gynecology Department at a University Hospital. INTERVENTION: Laparoscopic enucleation and excision of retroperitoneal cysts. CONCLUSION: Retroperitoneal cysts are rare lesions associated with numerous complications including compression on neighbouring organs, infection, rupture and malignant transformation...
May 18, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29780894/multiple-re-entry-closures-after-tevar-for-ruptured-chronic-post-dissection-thoraco-abdominal-aortic-aneurysm
#7
R Kinoshita, F Ganaha, J Ito, N Ohyama, N Abe, T Yamazato, H Munakata, K Mabuni, T Kugai
Introduction: Although thoracic endovascular aortic repair (TEVAR) has become a promising treatment for complicated acute type B dissection, its role in treating chronic post-dissection thoraco-abdominal aortic aneurysm (TAA) is still limited owing to persistent retrograde flow into the false lumen (FL) through abdominal or iliac re-entry tears. Report: A case of chronic post-dissection TAA treatment, in which a dilated descending FL ruptured into the left thorax, is described...
2018: EJVES Short Reports
https://www.readbyqxmd.com/read/29780721/type-b-aortic-dissection-new-perspectives
#8
REVIEW
Marc A A M Schepens
Background: Stanford type B aortic dissection is one of the aortic catastrophes with a high mortality and morbidity that needs immediate or delayed treatment, either surgically or endovascularly. This comprehensive review article addresses the current status of open, endovascular and hybrid treatment options for type B aortic dissections with the focus on new therapeutic perspectives. Methods: Evaluation of currently available evidence based on randomized and registry data and personal experience...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29780071/symptomatic-remote-cyst-after-bcnu-wafer-implantation-for-malignant-glioma
#9
Hideaki Matsumura, Eiichi Ishikawa, Masahide Matsuda, Noriaki Sakamoto, Hiroyoshi Akutsu, Shingo Takano, Akira Matsumura
A 43-year-old man was operated on for right frontal oligoastrocytoma. 14 years after the surgery, magnetic resonance imaging and positron emission tomography revealed a new lesion near the surgical cavity. He underwent gross total resection of the lesion and implantation of bis-chloroethylnitrosourea (BCNU) wafers after intraoperative pathological diagnosis of recurrent high-grade glioma. A few days after the operation, the level of consciousness gradually worsened and left hemiparesis developed. A computed tomography scan revealed a cyst remote to the surgical cavity which did not exist 3 days prior...
May 21, 2018: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/29780069/successful-rescue-of-a-ruptured-tracheoinnominate-fistula-with-extracorporeal-membrane-oxygenation-endovascular-stents-and-debranching-surgical-bypass
#10
Yu-San Chien, Yen-Chun Chao, Kuo-Sheng Lee, Kung-Hong Hsu
We reported a case of ruptured tracheoinnominate fistula in a 14-year-old boy with history of repeated sternotomy. Tracheostomy was performed at age 2 years. Slide tracheoplasty was done at age 13 years. He presented to outpatient clinic with episodic hemosputum. Massive blood emanated from stoma during bronchoscopy evaluation. Venous-arterial extracorporeal membrane oxygenation was installed for resuscitation. A contrast-enhanced computed tomography (CT) and angiography confirmed the diagnosis. Immediate control of bleeding was achieved by an endovascular stent graft deployed at innominate artery...
May 18, 2018: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29777919/brain-to-bone-what-is-the-contribution-of-the-brain-to-skeletal-homeostasis
#11
REVIEW
Anna Idelevich, Roland Baron
The brain, which governs most, if not all, physiological functions in the body, from the complexities of cognition, learning and memory, to the regulation of basal body temperature, heart rate and breathing, has long been known to affect skeletal health. In particular, the hypothalamus - located at the base of the brain in close proximity to the medial eminence, where the blood-brain-barrier is not as tight as in other regions of the brain but rather "leaky", due to fenestrated capillaries - is exposed to a variety of circulating body cues, such as nutrients (glucose, fatty acids, amino acids), and hormones (insulin, glucagon, leptin, adiponectin) [1-3]...
May 16, 2018: Bone
https://www.readbyqxmd.com/read/29775155/long-term-surgical-outcomes-following-transsphenoidal-surgery-in-patients-with-rathke-s-cleft-cysts
#12
Michelle Lin, Michelle A Wedemeyer, Daniel Bradley, Daniel A Donoho, Vance L Fredrickson, Martin H Weiss, John D Carmichael, Gabriel Zada
OBJECTIVE Rathke's cleft cysts (RCCs) are benign epithelial lesions of the sellar region typically treated via a transsphenoidal approach with cyst fenestration and drainage. At present, there is limited evidence to guide patient selection for operative treatment. Furthermore, there is minimal literature describing factors contributing to cyst recurrence. METHODS The authors conducted a retrospective analysis of 109 consecutive cases of pathology-confirmed RCCs treated via a transsphenoidal approach at a single center from 1995 to 2016...
May 18, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29766945/proposed-solution-for-dorsal-internal-carotid-artery-aneurysms-suggestion-of-a-novel-new-clip-design
#13
Ashish Aggarwal, Manarshhjot Singh, Parveen Kalra
Dorsal internal carotid artery (ICA) aneurysms are notorious for their high morbidity and mortality. They have an extremely fragile wall and have a high chance of rupture and clip slippage during the intraoperative and postoperative period. Strategies proposed to mitigate these problems encompass including part of the normal ICA wall in addition to neck of aneurysm in clip blades, as well as the use of encircling materials (silicon, cellulose, Weck's clip) over a clip. The Achilles' heel of the problem is to take an appropriate thickness of the normal ICA in clip blades...
May 2018: Neurology India
https://www.readbyqxmd.com/read/29763456/comprehensive-evaluation-of-blood-brain-barrier-forming-micro-vasculatures-reference-and-marker-genes-with-cellular-composition
#14
Mei Dai, Yi Lin, Salim S El-Amouri, Mara Kohls, Dao Pan
Primary brain microvessels (BrMV) maintain the cellular characters and molecular signatures as displayed in vivo, and serve as a vital tool for biomedical research of the blood-brain barrier (BBB) and the development/optimization of brain drug delivery. The variations of relative purities or cellular composition among different BrMV samples may have significant consequences in data interpretation and research outcome, especially for experiments with high-throughput genomics and proteomics technologies. In this study, we aimed to identify suitable reference gene (RG) for accurate normalization of real-time RT-qPCR analysis, and determine the proper marker genes (MG) for relative purity assessment in BrMV samples...
2018: PloS One
https://www.readbyqxmd.com/read/29758301/lipid-roles-in-herg-function-and-interactions-with-drugs
#15
REVIEW
Meruyert Kudaibergenova, Laura L Perissinotti, Sergei Y Noskov
Human-ether-a-go-go-related channel (hERG) is a voltage gated potassium channel (Kv 11.1) abundantly expressed in heart and brain tissues. In addition to playing an important role in mediation of repolarizing K+ currents (IKr ) in Action Potential (AP), hERG is notorious for its propensity to interact with various medications. The drug-induced block of K+ currents across hERG channel are strongly associated with dysrhythmic conditions collectively known as drug-induced long-QT-syndrome. The recent availability of the high-resolution Cryo-EM structures for the hERG channel has provided unique opportunity to resolve structural mechanisms involved into the process of voltage-gating of hERG channels, map various roles played by components of ventricular and neuronal membranes and then to connect it to cellular pathways through which diverse chemical compounds might be affecting function of the channel...
May 11, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29755232/augmentation-of-fenestrated-pedicle-screws-with-cement-in-patients-with-osteoporotic-spine
#16
Mahmoud Abousayed, Joseph Gamal Boktor, Ahmed Maher Sultan, Wael Koptan, Yasser El-Miligui
Background: Backing out and failure of pedicle screws in patients with osteoporosis is becoming a big problem due to wide use of these screws nowadays. Purpose: The aim of this study is to evaluate the purchase of fenestrated pedicle screws augmented with cement in patients with osteoporosis. Study Design: This was retrospective observational study. Patients and Methods: From May 2015 to January 2016, 25 patients with a poor bone stock condition underwent posterior fixation by fenestrated pedicle screws and cement augmentation...
January 2018: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/29755072/-primary-pulmonary-vein-stenosis-developed-after-bidirectional-glenn-procedure-report-of-two-cases
#17
Masatsugu Terada, Yukihiro Yoshimura, Yusuke Yamamoto, Akinori Hirano, Koichi Miyata, Naoya Fukushima, Hirotaka Oki, Masaru Miura
We experienced 2 cases of primary pulmonary vein stenosis(PVS),which developed after a bidirectional Glenn procedure was performed for complex heart defects with normal pulmonary venous return. Although the patients successfully underwent primary sutureless repair for left PVS, restenosis of the affected pulmonary veins occurred several months after surgery in both patients. Stent implantation followed by balloon angioplasty was performed for stent stenosis in 1 patient without effect. However, the patient later underwent a successful fenestrated Fontan procedure...
March 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29747936/pulmonary-screening-in-subjects-after-the-fontan-procedure
#18
Deborah R Liptzin, Michael V Di Maria, Adel Younoszai, Michael R Narkewicz, Sarah L Kelly, Kelly R Wolfe, Livia A Veress
OBJECTIVES: To review the pulmonary findings of the first 51 patients who presented to our interdisciplinary single-ventricle clinic after undergoing the Fontan procedure. STUDY DESIGN: We performed an Institutional Review Board-approved retrospective review of 51 patients evaluated following the Fontan procedure. Evaluation included history, physical examination, pulmonary function testing, and 6-minute walk. Descriptive statistics were used to describe the population and testing data...
May 7, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29741293/minimally-invasive-surgery-for-superior-semicircular-canal-dehiscence-results-of-a-four-fenestration-technique-in-twenty-one-adults
#19
Raquel Nogueira, Benjamin Verillaud, Charlotte Hautefort, Domitille Fiaux-Camous, Romain Kania, Philippe Herman
Superior canal semicircular dehiscence (SCCD) may cause vestibular and audiological symptoms that are sometimes debilitating. Computed tomography (CT) and the vestibular evoked myogenic potential (VEMP) test are essential for the diagnosis of SCCD. Various surgical techniques have been developed to manage SCCD but have many associated complications. Our technique uses an approach that otologists and surgeons are highly familiar with and that has other advantages, such as minimizing surgical trauma and preventing recurrences...
May 9, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29736360/metachronous-bilateral-painless-foot-drop-secondary-to-spinal-stenosis-case-report
#20
Luis A Robles
Foot drop (FD) is an uncommon manifestation of nerve root compression secondary to lumbar degenerative disease (LDD). In most of these patients, FD is unilateral and is associated with low back pain and leg pain. A small number of cases have been described with bilateral FD, which is reported to occur simultaneously in a synchronous fashion. A 63-year-old male with a remote history of spinal surgery due to left painless FD presented with a new episode of right FD, this new FD initiated suddenly and it was not associated with low back pain or radicular pain...
March 5, 2018: Curēus
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