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https://www.readbyqxmd.com/read/28326755/predicting-sleep-related-oxygen-desaturation
#1
Karel Calero, Mark Rumbak
No abstract text is available yet for this article.
March 22, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28324969/a-clinical-study-of-short-term-sternal-photoplethysmography-recordings-from-patients-with-obstructive-airways-diseases
#2
Shadi S Chreiteh, Dorthe B Saadi, Bo Belhage, Nassim Nabipour, Karsten Hoppe, Erik V Thomsen
Traditionally, measurements of the oxygen saturation (SpO2) has been confound to the extremities. In this study, we therefore investigated the possibility for reliable estimation of clinically relevant SpO2 levels from photoplethysmography (PPG) obtained on the sternum of patients with obstructive airway diseases. We initiated the study with a calibration of a prototype sternal PPG sensor. In accordance with the ISO 80601-2-61:2011 guidelines, the calibration was conducted as a controlled desaturation study...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28323585/feasibility-of-hypoxic-challenge-testing-in-children-and-adolescents-with-congenital-heart-and-lung-disease
#3
Mandy E Spoorenberg, Erik H J Hulzebos, Tim Takken
BACKGROUND: This is a cross-sectional observational study to investigate the safety and feasibility of integrating changing body positions and physical activity in a hypoxic challenge test (HCT). The secondary objective was to compare oxygen saturation (Spo2) in two different locations (forehead and finger). METHODS: Included were 12 pediatric to young adult patients with congenital heart (N = 7) or lung disease (N = 5). An HCT was performed using breathing room air (21% oxygen) while sitting and breathing a normobaric hypoxic gas mixture (15% oxygen) through a facemask while seated, lying supine, standing, walking 3 km/h, and walking 5 km/h in a nonrandomized order...
December 1, 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28320993/intractable-back-pain-after-coil-embolization-of-giant-veno-venous-collaterals-in-a-patient-with-fontan-circulation
#4
Seigo Okada, Masahiro Kamada, Naomi Nakagawa, Yukiko Ishiguchi, Yuji Moritoh, Mayuko Shohi, Kengo Okamoto, Shunji Hasegawa, Shouichi Ohga
Veno-venous collaterals are sometimes seen in patients after the Fontan procedure. A 28-year-old female with tricuspid atresia who underwent the Fontan procedure had oxygen desaturation due to a giant veno-venous collateral. Coil embolization was performed for the collateral. After the procedure, she complained of severe back pain. Anti-inflammatory analgesics and steroids were not effective, although carbamazepine promptly relieved the intractable pain. Treatment-related pain after coil embolization for veno-venous collaterals in patients with Fontan physiology is quite rare, although cardiologists must recognize a critical condition to be differentiated from vascular occlusion...
March 21, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28319511/the-first-us-clinical-experience-with-computer-assisted-propofol-sedation-a-retrospective-observational-comparative-study-on-efficacy-safety-efficiency-and-endoscopist-and-patient-satisfaction
#5
Otto S Lin, Richard A Kozarek, Deborah Tombs, Danielle La Selva, Wade Weigel, Ryan Beecher, Ana Jensen, Michael Gluck, Andrew Ross
BACKGROUND: Computer-assisted propofol sedation (CAPS) is now approved for moderate sedation of American Society of Anesthesiologists (ASA) class I and II patients undergoing routine endoscopy. As the first US medical center to adopt CAPS for routine clinical use, we compared patient and endoscopist satisfaction with CAPS versus midazolam and fentanyl (MF) sedation. METHODS: Patients who underwent elective outpatient upper endoscopy and colonoscopy with CAPS were compared with concurrent patients sedated with MF...
March 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28315149/can-myofunctional-therapy-increase-tongue-tone-and-reduce-symptoms-in-children-with-sleep-disordered-breathing
#6
Maria Pia Villa, Melania Evangelisti, Susy Martella, Mario Barreto, Marco Del Pozzo
PURPOSE: Data in the literature suggest that myofunctional therapy (MT) may be able to play a role in the treatment of children with sleep-disordered breathing (SDB). Our study investigated the effectiveness of MT in reducing respiratory symptoms in children with SDB by modifying tongue tone. METHODS: Polysomnographic recordings were performed at baseline to assess obstructive sleep apnea (OSA) severity in 54 children (mean age 7.1 ± 2.5 years, 29 male) with SDB...
March 18, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28300569/obesity-as-an-effect-modifier-in-sleep-disordered-breathing-and-post-cardiac-surgery-atrial-fibrillation
#7
Roop Kaw, Samer El Zarif, Lu Wang, James Bena, Eugene Blackstone, Reena Mehra
INTRODUCTION: As the inter-relationships of objectively-ascertained sleep disordered breathing (SDB), post-cardiac surgery atrial fibrillation (PCSAF) and obesity remain unclear; we aimed to further investigate in a clinic-based cohort. METHODS: Patients with polysomnography (PSG) and cardiac surgery (coronary artery bypass surgery and/or valvular surgery) within 3 years, from January 2009 to January 2014 were identified excluding those with pre-existing AF. Logistic models were used to determine the association of SDB (apnea hypopnea index (AHI) per 5 unit increase) and secondary predictors [central sleep apnea (CSA) (central apnea index>5) and oxygen desaturation index (ODI)] with PCSAF...
March 11, 2017: Chest
https://www.readbyqxmd.com/read/28296212/red-cell-distribution-width-and-uric-acid-in-patients-with-obstructive-sleep-apnea
#8
A Sunnetcioglu, H Gunbatar, H Yıldız
BACKGROUND: Obstructive sleep apnea (OSA), characterized by recurrent partial or complete pharyngeal closure, resulting in apnea or hypopnea, is closely associated with cardiovascular disorders (CVDs). Elevated red cell distribution width (RDW) and serum uric acid (SUA) levels have also been associated with CVDs and the consequent mortality. The aim of this study is to determine SUA levels and RDW in patients with OSA which is major a risk factor for CVDs. METHODS: This was a retrospective study involving 600 subjects evaluated by polysomnography...
March 13, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28286737/pdgf-induced-fibroblast-growth-requires-monounsaturated-fatty-acid-production-by-stearoyl-coa-desaturase
#9
Alexandra Coomans de Brachène, Nicolas Dif, Audrey de Rocca Serra, Chloé Bonnineau, Amélie I Velghe, Yvan Larondelle, Donatienne Tyteca, Jean-Baptiste Demoulin
Stearoyl-coenzyme A desaturase (SCD) catalyzes the Δ9-cis desaturation of saturated fatty acids (SFA) to generate monounsaturated fatty acids (MUFA). This enzyme is highly up-regulated by platelet-derived growth factor (PDGF) in human fibroblasts. Accordingly, the analysis of cellular fatty acids by gas chromatography showed that PDGF significantly increased the proportion of MUFA, particularly palmitoleate, in cellular lipids. To further analyze the role of SCD in fibroblasts, we used small hairpin RNA targeting SCD (shSCD), which decreased the MUFA content...
March 2017: FEBS Open Bio
https://www.readbyqxmd.com/read/28284883/etomidate-versus-propofol-sedation-for-complex-upper-endoscopic-procedures-a-prospective-double-blinded-randomized-controlled-trial
#10
Mi Gang Kim, Se Woo Park, Jae Hyun Kim, Jin Lee, Sea Hyub Kae, Hyun Joo Jang, Dong Hee Koh, Min Ho Choi
BACKGROUND AND AIMS: Although a growing body of evidence demonstrates that propofol-induced deep sedation can be effective and performed safely, cardiopulmonary adverse events have been frequently observed. Etomidate is a new emerging drug that provides hemodynamic and respiratory stability, even in high-risk patient groups. The objective of this study was to compare safety and efficacy profiles of etomidate and propofol for endoscopic sedation. METHODS: A total of 128 patients undergoing endoscopic ultrasound were randomized to receive either etomidate or propofol blinded administered by a registered nurse...
March 8, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28283852/short-term-general-anesthesia-for-retro-bulbar-block-in-ophthalmic-surgery-generates-no-significant-hypercapnia
#11
Werner Baulig, Monica Weber, Beatrice Beck-Schimmer, Oliver M Theusinger, Peter Biro
To assess the impact of short time hypnosis for retro-bulbar anesthesia on ventilation in patients undergoing ophthalmic surgery of the anterior eye chamber. In all patients, a combined continuous transcutaneous carbon dioxide tension (PtcCO2) and partial oxygen saturation (SpO2) measurement was applied in addition to routine monitoring. To enable unconscious application of retro-bulbar anesthesia, intravenous thiopental was given in one to multiple bolus doses. Transient breathing support included chin lift, Esmarch maneuver and manual hand-bag ventilation via face mask...
March 11, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28282060/visual-dysfunction-and-its-correlation-with-retinal-changes-in-patients-with-alzheimer-s-disease
#12
V Polo, M J Rodrigo, E Garcia-Martin, S Otin, J M Larrosa, M I Fuertes, M P Bambo, L E Pablo, M Satue
AimTo evaluate visual dysfunction and its correlation with structural changes in the retina in patients with Alzheimer's disease (AD).MethodsPatients with AD (n=24) and controls (n=24) underwent evaluation of visual acuity (VA), color vision (using the Farnsworth and L'Anthony desaturated (D) 15 color tests), and contrast sensitivity vision (CSV; using the Pelli-Robson chart and CSV-1000E test) to measure visual dysfunction. Structural measurements of the retinal nerve fiber layer (RNFL) and macular thickness were obtained using spectral domain-optical coherence tomography (SD-OCT)...
March 10, 2017: Eye
https://www.readbyqxmd.com/read/28279712/attention-in-natural-scenes-affective-motivational-factors-guide-gaze-independently-of-visual-salience
#13
Judith Schomaker, Daniel Walper, Bianca C Wittmann, Wolfgang Einhäuser
In addition to low-level stimulus characteristics and current goals, our previous experience with stimuli can also guide attentional deployment. It remains unclear, however, if such effects act independently or whether they interact in guiding attention. In the current study, we presented natural scenes including every-day objects that differed in affective-motivational impact. In the first free-viewing experiment, we presented visually-matched triads of scenes in which one critical object was replaced that varied mainly in terms of motivational value, but also in terms of valence and arousal, as confirmed by ratings by a large set of observers...
March 14, 2017: Vision Research
https://www.readbyqxmd.com/read/28278312/spatial-filtering-color-constancy-and-the-color-changing-dress
#14
Erica L Dixon, Arthur G Shapiro
The color-changing dress is a 2015 Internet phenomenon in which the colors in a picture of a dress are reported as blue-black by some observers and white-gold by others. The standard explanation is that observers make different inferences about the lighting (is the dress in shadow or bright yellow light?); based on these inferences, observers make a best guess about the reflectance of the dress. The assumption underlying this explanation is that reflectance is the key to color constancy because reflectance alone remains invariant under changes in lighting conditions...
March 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28277258/continuous-versus-single-shot-brachial-plexus-block-and-their-relationship-to-discharge-barriers-and-length-of-stay
#15
Matthew Thompson, Robert Simonds, Bryce Clinger, Kristen Kobulnicky, Adam P Sima, Laura Lahaye, N Douglas Boardman
BACKGROUND: Brachial plexus block has been associated with improved pain control and decreased length of stay in patients undergoing upper extremity arthroplasty. Continuous delivery is associated with a shorter length of stay; however, comparisons to single-shot delivery in this setting are scarce. As the paradigm shifts to outpatient arthroplasty in the era of bundled payments, there exists a strong impetus to identify the most effective mode of analgesia associated with the least risk to patients...
October 26, 2016: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28275024/levetiracetam-induced-eosinophilic-pneumonia
#16
Aisling Fagan, Jonathan Fuld, Elaine Soon
Levetiracetam is widely regarded as a benign antiepileptic drug, compared to older antiepileptic medication. We report a case of eosinophilic pneumonia due to levetiracetam use in a non-smoking woman aged 59 years with no previous respiratory history. Our patient presented with exertional breathlessness and marked desaturation on exertion. She displayed 'reverse bat-wing' infiltrates on her chest radiograph and peripheral eosinophilia on a complete blood count. Her symptoms, radiology and peripheral eosinophilia resolved completely with cessation of levetiracetam and a course of prednisolone...
March 8, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28274235/multicenter-study-on-the-effectiveness-of-the-pre-epiglottic-baton-plate-for-airway-obstruction-and-feeding-problems-in-robin-sequence
#17
Christian F Poets, Christoph Maas, Wolfgang Buchenau, Joerg Arand, Anne Vierzig, Bert Braumann, Silvia Müller-Hagedorn
BACKGROUND: Treatment of Robin sequence is often either invasive or of unproven effectiveness. The pre-epiglottic baton plate (PEBP) is a well-studied alternative, yet is not widely applied internationally. We report on a prospective 3-center cohort study investigating this treatment. Based on an agreed protocol, parents of infants with Robin sequence referred to participating centers were offered enrollment, which involved taking a maxillary cast followed by endoscopy to fit the plate and sleep studies to monitor its effectiveness...
March 9, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28274023/evaluation-of-fastrach-laryngeal-mask-airway-as-an-alternative-to-fiberoptic-bronchoscope-to-manage-difficult-airway-a-comparative-study
#18
Radhey Shyam, Ajay Kumar Chaudhary, Pushplata Sachan, Prithvi Kumar Singh, Gyan Prakash Singh, Vinod Kumar Bhatia, Girish Chandra, Dinesh Singh
INTRODUCTION: Awake intubation via Fiberoptic Bronchoscope (FB) is the gold standard for management of difficult airway but patients had to face problems like oxygen desaturation, tachycardia, hypertension and anxiety due to awake state. This study was conducted to assess feasibility of Fastrach Laryngeal Mask Airway (FLMA) to manage difficult airway as a conduit for intubation as well as for ventilation. MATERIALS AND METHODS: After ethical approval and informed consent, 60 patients with difficult airway were randomly enrolled in FB group and FLMA group...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28273699/-use-of-noninvasive-high-frequency-oscillatory-ventilation-in-very-low-birth-weight-infants
#19
C H Wang, L P Shi, X L Ma, H J Lin, Y P Xu, L Z Du
Objective: To evaluate the effectiveness and safety of the use of noninvasive high-frequency oscillation ventilation (nHFOV) in very low birth weight infants. Method: A total of 36 cases received nHFOV between January 2016 and October 2016 in Children's Hospital, Zhejiang University School of Medicine, including 24 males and 12 females, with the gestational age of (27.5±2.5) weeks and birth weight of(980±318)g. The data of the ventilator settings, side effects, and changes of the respiratory function before and after nHFOV were collected and analyzed retrospectively...
March 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28270188/pulmonary-alveolar-proteinosis-and-first-successful-whole-lung-lavage-in-sri-lanka-a-case-report
#20
Janith Galhenage, Buddhika Weerasinghe, Wadasinghe Dilesha, Roshana Constantine, Bandu Gunasena
BACKGROUND: Pulmonary alveolar proteinosis is a rare disease characterized by accumulation of lipoproteinaceous material within alveoli. There are three clinically distinct forms: congenital, acquired and secondary. Whole lung lavage is currently the gold standard therapy for severe cases of pulmonary alveolar proteinosis. In Sri Lanka this is the first reported successful whole lung lavage for a patient with pulmonary alveolar proteinosis. CASE PRESENTATION: We describe the case of a 15-year-old Sri Lankan girl who presented with symptoms of progressive shortness of breath and dry cough for 6 months' duration...
March 8, 2017: Journal of Medical Case Reports
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