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https://www.readbyqxmd.com/read/27854117/treatment-of-neonates-with-respiratory-distress-syndrome-by-proportional-assist-ventilation-plus-synchronized-intermittent-mandatory-ventilation-a-comparison-study
#1
Rong Wu, Zhao F Tian, Xiang Y Kong, Shao D Hua, Jin H Hu, Guo F Zhen
BACKGROUND: The proportion assisted ventilation (PAV) can improve patient-ventilator interaction, reduce the incidence of end-expiratory asynchrony and increase the time of synchrony. PAV could compensate for the leaks by Elastic and resistive unloading and thus is ideal for neonates with uncuffed airways. The aim of this study was to compare the relevant clinical parameters of neonates with respiratory distress syndrome(RDS) who are surported by PAV plus synchronized intermittent mandatory ventilation (SIMV) and SIMV...
November 17, 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/27623133/impact-of-targeted-volume-ventilation-on-pulmonary-dynamics-in-preterm-infants-with-respiratory-distress-syndrome
#2
Senem Alkan Ozdemir, Esra Arun Ozer, Ozkan Ilhan, Sumer Sutcuoglu
BACKGROUND: Mechanical ventilation is an essential therapy in the treatment of respiratory failure in preterm infants. However, optimal ventilation strategy continues to be difficult to define. OBJECTIVE: To compare the effects of volume guarantee (VG) combined with intermittent mandatory ventilation (SIMV) and VG combined with pressure support ventilation (PSV) on the pulmonary mechanics and short term prognosis in preterm infants with respiratory distress syndrome...
September 13, 2016: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27581993/synchronized-mechanical-ventilation-for-respiratory-support-in-newborn-infants
#3
Anne Greenough, Thomas E Rossor, Adesh Sundaresan, Vadivelam Murthy, Anthony D Milner
BACKGROUND: During synchronised mechanical ventilation, positive airway pressure and spontaneous inspiration coincide. If synchronous ventilation is provoked, adequate gas exchange should be achieved at lower peak airway pressures, potentially reducing baro/volutrauma, air leak and bronchopulmonary dysplasia. Synchronous ventilation can potentially be achieved by manipulation of rate and inspiratory time during conventional ventilation and employment of patient-triggered ventilation. OBJECTIVES: To compare the efficacy of:(i) synchronised mechanical ventilation, delivered as high-frequency positive pressure ventilation (HFPPV) or patient-triggered ventilation (assist control ventilation (ACV) and synchronous intermittent mandatory ventilation (SIMV)), with conventional ventilation or high-frequency oscillation (HFO);(ii) different types of triggered ventilation (ACV, SIMV, pressure-regulated volume control ventilation (PRVCV), SIMV with pressure support (PS) and pressure support ventilation (PSV))...
September 1, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27539719/synchronized-mechanical-ventilation-for-respiratory-support-in-newborn-infants
#4
REVIEW
Anne Greenough, Vadivelam Murthy, Anthony D Milner, Thomas E Rossor, Adesh Sundaresan
BACKGROUND: During synchronised mechanical ventilation, positive airway pressure and spontaneous inspiration coincide. If synchronous ventilation is provoked, adequate gas exchange should be achieved at lower peak airway pressures, potentially reducing baro/volutrauma, air leak and bronchopulmonary dysplasia. Synchronous ventilation can potentially be achieved by manipulation of rate and inspiratory time during conventional ventilation and employment of patient-triggered ventilation. OBJECTIVES: To compare the efficacy of:(i) synchronised mechanical ventilation, delivered as high-frequency positive pressure ventilation (HFPPV) or patient-triggered ventilation (assist control ventilation (ACV) and synchronous intermittent mandatory ventilation (SIMV)), with conventional ventilation or high-frequency oscillation (HFO);(ii) different types of triggered ventilation (ACV, SIMV, pressure-regulated volume control ventilation (PRVCV), SIMV with pressure support (PS) and pressure support ventilation (PSV))...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27411450/lung-protective-ventilation-in-patients-with-brain-injury-a-multicenter-cross-sectional-study-and-questionnaire-survey-in-china
#5
Xu-Ying Luo, Ying-Hong Hu, Xiang-Yuan Cao, Yan Kang, Li-Ping Liu, Shou-Hong Wang, Rong-Guo Yu, Xiang-You Yu, Xia Zhang, Bao-Shan Li, Zeng-Xiang Ma, Yi-Bing Weng, Heng Zhang, De-Chang Chen, Wei Chen, Wen-Jin Chen, Xiu-Mei Chen, Bin Du, Mei-Li Duan, Jin Hu, Yun-Feng Huang, Gui-Jun Jia, Li-Hong Li, Yu-Min Liang, Bing-Yu Qin, Xian-Dong Wang, Jian Xiong, Li-Mei Yan, Zheng-Ping Yang, Chen-Ming Dong, Dong-Xin Wang, Qing-Yuan Zhan, Shuang-Lin Fu, Lin Zhao, Qi-Bing Huang, Ying-Guang Xie, Xiao-Bo Huang, Guo-Bin Zhang, Wang-Bin Xu, Yuan Xu, Ya-Ling Liu, He-Ling Zhao, Rong-Qing Sun, Ming Sun, Qing-Hong Cheng, Xin Qu, Xiao-Feng Yang, Ming Xu, Zhong-Hua Shi, Han Chen, Xuan He, Yan-Lin Yang, Guang-Qiang Chen, Xiu-Mei Sun, Jian-Xin Zhou
BACKGROUND: Over the years, the mechanical ventilation (MV) strategy has changed worldwide. The aim of the present study was to describe the ventilation practices, particularly lung-protective ventilation (LPV), among brain-injured patients in China. METHODS: This study was a multicenter, 1-day, cross-sectional study in 47 Intensive Care Units (ICUs) across China. Mechanically ventilated patients (18 years and older) with brain injury in a participating ICU during the time of the study, including traumatic brain injury, stroke, postoperation with intracranial tumor, hypoxic-ischemic encephalopathy, intracranial infection, and idiopathic epilepsy, were enrolled...
July 20, 2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27383316/clinical-research-about-airway-pressure-release-ventilation-for-moderate-to-severe-acute-respiratory-distress-syndrome
#6
J-Q Li, N Li, G-J Han, C-G Pan, Y-H Zhang, X-Z Shi, J-Y Xu, B Lu, M-Q Li
OBJECTIVE: To evaluate clinical effects of airway pressure release ventilation (APRV) in patients suffering from moderate to severe acute respiratory distress syndrome (ARDS).e of a patient presented with significant high aminotransferase levels due to the first human R. aeschlimannii infection ever detected in Italy. The hypothesis of rickettsiosis was made on the basis of a comprehensive medical history and was confirmed by serological tests. Molecular analyses made on a sample of hepatic tissue revealed the presence of a rickettsial species never found before in human liver...
June 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27264784/nitrogen-dioxide-reducing-ascorbic-acid-technologies-in-the-ventilator-circuit-leads-to-uniform-no-concentration-during-inspiration
#7
Matthew J Pezone, Matthew G Wakim, Ryan J Denton, Lucas G Gamero, Robert F Roscigno, Richard J Gilbert, Mark A Lovich
Conventional inhaled NO systems deliver NO by synchronized injection or continuous NO flow in the ventilator circuitry. Such methods can lead to variable concentrations during inspiration that may differ from desired dosing. NO concentrations in these systems are generally monitored through electrochemical methods that are too slow to capture this nuance and potential dosing error. A novel technology that reduces NO2 into NO via low-resistance ascorbic-acid cartridges just prior to inhalation has recently been described...
August 31, 2016: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/27095997/comparing-the-effects-of-adaptive-support-ventilation-and-synchronized-intermittent-mandatory-ventilation-on-intubation-duration-and-hospital-stay-after-coronary-artery-bypass-graft-surgery
#8
Ahmadreza Yazdannik, Hadi Zarei, Gholamreza Massoumi
BACKGROUND: Different modes of mechanical ventilation are used for respiratory support after coronary artery bypass graft (CABG). This study aimed to compare the effect(s) of using adaptive support ventilation (ASV) and synchronized intermittent mandatory ventilation (SIMV) on the length of mechanical ventilation (intubation duration) and hospital stay after coronary artery bypass graft surgery. MATERIALS AND METHODS: In a randomized control trial, 64 patients were ventilated with ASV as the experiment group or with SIMV as the control group after CABG surgery in Chamran Hospital of Isfahan University of Medical Sciences...
March 2016: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/26908715/ventilator-induced-pulse-pressure-variation-in-neonates
#9
Linda Heskamp, Benno Lansdorp, Jeroen Hopman, Joris Lemson, Willem-Pieter de Boode
During positive pressure ventilation, arterial pressure variations, like the pulse pressure variation (PPV), are observed in neonates. However, the frequency of the PPV does not always correspond with the respiratory rate. It is hypothesized that PPV is caused by cardiopulmonary interaction, but that this mismatch is related to the low respiratory rate/heart rate ratio. Therefore, the goal of this study is to investigate the relation between PPV and ventilation in neonates. A prospective observational cross-sectional study was carried out in a third-level neonatal intensive care unit in a university hospital...
February 2016: Physiological Reports
https://www.readbyqxmd.com/read/26894156/ventilating-patient-with-refractory-hypercarbia-use-of-aprv-mode
#10
Zia Arshad, Ravi Prakash, Swati Aggarwal, Sapna Yadav
A 70-year-old patient referred to our critical care unit with the diagnosis of type II respiratory failure with shock. Patient was a known case of COPD for last 20 years. His chest radiology revealed bilateral infiltrates. Patient was managed conservatively in the form of antibiotics, vasopressor and ventilatory support with SIMV/VC mode. After ventilation with SIMV/VC mode for half an hour his blood gases revealed increasing PaCO2 levels. The same result was obtained with PC mode and ASV and his PaCO2 level reached above 170 mmHg...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26805529/-the-clinical-effect-of-airway-pressure-release-ventilation-for-acute-lung-injury-acute-respiratory-distress-syndrome
#11
Shaohua Song, Huiyu Tian, Xiufen Yang, Zhenjie Hu
OBJECTIVE: To evaluate the effect of airway pressure release ventilation (APRV) in patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS), to evaluate the extent of ventilator-induced lung injury (VILI), and to explore its possible mechanism. METHODS: A prospective study was conducted in the Department of Critical Care Medicine of the First Hospital of Hebei Medical University from December 2010 to February 2012. The patients with ALI/ARDS were enrolled...
January 2016: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/26793348/initial-synchronized-intermittent-mandatory-ventilation-versus-assist-control-ventilation-in-treatment-of-moderate-acute-respiratory-distress-syndrome-a-prospective-randomized-controlled-trial
#12
Jian Luo, Mao-Yun Wang, Bin-Miao Liang, He Yu, Fa-Ming Jiang, Ting Wang, Chao-Li Shi, Pei-Jun Li, Dan Liu, Xiao-Ling Wu, Zong-An Liang
BACKGROUND: Assist/control (A/C) ventilation may induce delirium in patients with acute respiratory distress syndrome (ARDS). We conducted a trial to determine whether initial synchronized intermittent mandatory ventilation with pressure support (SIMV + PS) could improve clinical outcomes in these patients. METHODS: Intubated patients with moderate ARDS were enrolled and we compared SIMV + PS with A/C. Identical sedation, analgesia and ventilation strategies were performed...
December 2015: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/26633188/treatment-of-neonates-with-meconium-aspiration-syndrome-by-proportional-assist-ventilation-and-synchronized-intermittent-mandatory-ventilation-a-comparison-study
#13
Rong Wu, Zhao-Fang Tian, Guo-Fang Zheng, Su-Fang Din, Zi-Bo Gao, Zhi-Chun Feng
BACKGROUND: This study aimed to compare the relevant clinical parameters of neonates with MAS who are supported by proportion assisted ventilation (PAV) and synchronized intermittent mandatory ventilation (SIMV). METHODS: Forty neonates diagnosed as MAS who required mechanical ventilation were divided randomly into PAV group and SIMV group (N.=20). The respiratory rate (RR), heart rate (HR), peak inspiratory pressure (PIP), mean arterial blood pressure (MABP), arterial-to-alveolar oxygen tension ratio (a/APO2), fraction of inspiration oxygen (FiO2), mean airway pressure (MAP) and tidal volume (VT) were measured before the ventilation, 1,12, 24, 48 hours after the ventilation and before weaning...
August 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/26301964/effect-of-ventilation-support-on-oxidative-stress-and-ischemia-modified-albumin-in-neonates
#14
Arzu Dursun, Nurullah Okumuş, Sara Erol, Tülin Bayrak, Ayşegül Zenciroğlu
BACKGROUND AND OBJECTIVE: Mechanical ventilation (MV) can induce oxidative stress, which plays a critical role in pulmonary injury in intubated neonates. Ischemia-modified albumin (IMA)-a variant of human serum albumin-is a novel biomarker of myocardial ischemia that occurs due to reactive oxygen species during ischemic insult. This study aimed to investigate IMA production due to oxidative stress induced during MV in neonates. MATERIALS AND METHODS: This study included 17 neonates that were ventilated using synchronized intermittent mechanical ventilation (SIMV; SIMV group) and 20 neonates ventilated using continuous positive airway pressure (CPAP; CPAP group)...
January 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/26290682/effects-of-ezetimibe-simvastatin-and-rosuvastatin-on-oxidative-stress-in-diabetic-neuropathy-a-randomized-double-blind-placebo-controlled-clinical-trial
#15
RANDOMIZED CONTROLLED TRIAL
Geannyne Villegas-Rivera, Luis Miguel Román-Pintos, Ernesto Germán Cardona-Muñoz, Oscar Arias-Carvajal, Adolfo Daniel Rodríguez-Carrizalez, Rogelio Troyo-Sanromán, Fermín Paul Pacheco-Moisés, Aldo Moreno-Ulloa, Alejandra Guillermina Miranda-Díaz
OBJECTIVE: To evaluate the effects of ezetimibe/simvastatin (EZE/SIMV) and rosuvastatin (ROSUV) on oxidative stress (OS) markers in patients with diabetic polyneuropathy (DPN). METHODS: We performed a randomized, double-blind, placebo-controlled phase III clinical trial in adult patients with Type 2 Diabetes Mellitus (T2DM) and DPN, as evaluated by composite scores and nerve conduction studies (NCS). Seventy-four subjects with T2DM were allocated 1 : 1 : 1 to placebo, EZE/SIMV 10/20 mg, or ROSUV 20 mg for 16 weeks...
2015: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/26148358/-russian-national-epidemiological-study-ruvent-the-use-of-artificial-lung-ventilation-in-the-intensive-therapy-in-children
#16
MULTICENTER STUDY
S G Suvorov, A U Lekmanov, A I Yaroshetskiy, D N Protsenko, B R Gelfand
UNLABELLED: Purpose of this part of the "RuVent" research is to study the real use of the various modes and parameters of prolonged respiratory support in children in Russia. MATERIALS AND METHODS: The study included 104 children from 29 ICUs (28 in Russian Federation, 1 in Ukraine) under the age of 15 years with ALV duration more than 12 hours in the period from February 7 to 11, 2011. The collection of information performed through online forms. RESULTS: Total lethality was 20...
March 2015: Anesteziologiia i Reanimatologiia
https://www.readbyqxmd.com/read/25881121/mechanical-ventilation-modes-for-respiratory-distress-syndrome-in-infants-a-systematic-review-and-network-meta-analysis
#17
REVIEW
Changsong Wang, Libo Guo, Chunjie Chi, Xiaoyang Wang, Lei Guo, Weiwei Wang, Nana Zhao, Yibo Wang, Zhaodi Zhang, Enyou Li
INTRODUCTION: The effects of different mechanical ventilation (MV) modes on mortality outcome in infants with respiratory distress syndrome (RDS) are not well known. METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library, EMBASE, MEDLINE, CINAHL, and Web of Science for studies published through April 2014 that assessed mortality in infants with RDS given different MV modes. We assessed studies for eligibility, extracted data, and subsequently pooled the data...
March 20, 2015: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/25823757/less-invasive-ventilation-in-extremely-low-birth-weight-infants-from-1997-to-2011-survey-versus-evidence
#18
Roland Gerull, Helen Manser, Helmut Küster, Tina Arenz, Stephan Arenz, Mathias Nelle
UNLABELLED: Evidence for target values of arterial oxygen saturation (SaO2), CO2, and pH has changed substantially over the last 20 years. A representative survey concerning treatment strategies in extremely low-birth-weight infants (ELBW) was sent to all German neonatal intensive care units (NICUs) treating ELBW infants in 1997. A follow-up survey was conducted in 2011 and sent to all NICUs in Germany, Austria, and Switzerland. During the observation period, NICUs targeting SaO2 of 80, 85, and 90 % have increased, while units aiming for 94 and 96 % decreased (all p < 0...
September 2015: European Journal of Pediatrics
https://www.readbyqxmd.com/read/25823397/a-comparison-of-high-frequency-jet-ventilation-and-synchronised-intermittent-mandatory-ventilation-in-preterm-lambs
#19
COMPARATIVE STUDY
Gabrielle C Musk, Graeme R Polglase, J Bert Bunnell, Ilias Nitsos, David Tingay, J Jane Pillow
PURPOSE: Synchronised intermittent mandatory ventilation (SIMV) and high-frequency jet ventilation (HFJV) are accepted ventilatory strategies for treatment of respiratory distress syndrome (RDS) in preterm babies. We hypothesised that SIMV and HFJV both facilitate adequate oxygenation and ventilation but that HFJV is associated with less lung injury. RESULTS: There were no differences in arterial oxygenation or partial pressure of carbon dioxide despite lower mean airway pressure during SIMV for most of the study...
December 2015: Pediatric Pulmonology
https://www.readbyqxmd.com/read/25777926/mechanical-ventilation-modes-for-respiratory-distress-syndrome-in-infants-a-systematic-review-and-network-meta-analysis
#20
Changsong Wang, Libo Guo, Chunjie Chi, Xiaoyang Wang, Lei Guo, Weiwei Wang, Nana Zhao, Yibo Wang, Zhaodi Zhang, Enyou Li
INTRODUCTION: The effects of different mechanical ventilation (MV) modes on mortality outcome in infants with respiratory distress syndrome (RDS) are not well known. METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library, EMBASE, MEDLINE, CINAHL, and Web of Science for studies published through April 2014 that assessed mortality in infants with RDS given different MV modes. We assessed studies for eligibility, extracted data, and subsequently pooled the data...
December 2015: Critical Care: the Official Journal of the Critical Care Forum
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