Chittawee Jiamton, Adinun Apivatgaroon, Saree Aunaramwat, Banchai Chawalitrujiwong, Chaiwat Chuaychoosakoon, Sitthiphong Suwannaphisit, Choen Jirawison, Chonlathan Iamsumang, Pinkawas Kongmalai, Pawaris Sukvanich, Pongtep Na Nakorn, Worawit Ongbumrungphan, Pawin Rattanasumrit, Suthee Tharakulphan, Thanachai Thongtanworapat, Faungchat Thammarakcharoen, Autcharaporn Srion, Jintamai Suwanprateeb, Bancha Chernchujit
Chronic osteomyelitis is still a serious health problem that causes disabling conditions and has an impact on the quality of life. The objective of this study was to determine the clinical efficacy and safety of localized antibiotics delivery via impregnated microporous nanohydroxyapatite (nHA-ATB) beads for chronic osteomyelitis treatment. A total of 62 patients were enrolled in this study. After radical surgical debridement, the bone defect was filled with three types of antibiotics (vancomycin or gentamicin or fosfomycin) impregnated HA beads...
June 15, 2023: Antibiotics