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Radio embolisation

L Eberlova, V Liska, H Mirka, T Gregor, Z Tonar, R Palek, M Skala, J Bruha, O Vycital, K Kalusova, S Haviar, M Kralickova, A Lametschwandtner
BACKGROUND: Pigs are frequently used as animal models in experimental medicine. To identify processes of vascular development or regression, vascular elements must be recognised and quantified in a three-dimensional (3D) arrangement. Vascular corrosion casts enable the creation of 3D replicas of vascular trees. The aim of our study was to identify suitable casting media and optimise the protocol for porcine liver vascular corrosion casting. MATERIALS AND METHODS: Mercox II® (Ladd Research, Williston, Vermont, USA) and Biodur E20® Plus (Biodur Products, Heidelberg, Germany) were tested in 4 porcine livers...
2016: Folia Morphologica (Warsz)
Monika Černá, Vladislav Třeška, Michal Krčma, Ondřej Daum, František Šlauf
INTRODUCTION: Vascular malformations of the thyroid gland represent a very rare, often accidentally diagnosed, disease that in the case of eufunctional goitre may be the cause of mechanical neck syndrome. The authors present here the complex differential-diagnosis and treatment approach and stress the importance of histopathology for determining the final diagnosis. CASE PRESENTATION: Using various imaging methods (ultrasound, multidetector computed tomography of the neck), the cause of breathing difficulties in a 64-year-old old man from the Czech Republic with normal thyroid gland function was found to be an arteriovenous malformation of the left lobe of his thyroid gland, 80 × 70 × 55 mm in size, reaching retrosternally between the major arteries branching from his aortic arch and displacing his trachea 10mm to the right...
February 2, 2015: Journal of Medical Case Reports
S Favelier, T Germain, P-Y Genson, J-P Cercueil, A Denys, D Krausé, B Guiu
The availability of intra-arterial hepatic therapies (radio and/or chemo-embolisation, intra-arterial hepatic chemotherapy) has convinced radiologists to perfect their knowledge of the anatomy of the liver arteries. These sometimes, complex procedures most often require selective arterial catheterization. Knowledge of the different arteries in the liver and the peripheral organs is therefore essential to optimize the procedure and avoid eventual complications. This paper aims to describe the anatomy of the liver arteries and the variants, applying it to angiography images, and to understand the implications of such variations in interventional radiological procedures...
June 2015: Diagnostic and Interventional Imaging
Lorenzo Andreana, Graziella Isgrò, Laura Marelli, Neil Davies, Dominic Yu, Shaunak Navalkissoor, Andrew K Burroughs
Traditional radiotherapy is only effective in treating hepatocellular cancer (HCC) in doses above 50 Gy, but this is above the recommended liver radiation exposure of about 35 Gy, which is an important limitation making this treatment unsuitable for routine clinical practice. Trans-arterial radio-embolisation (TARE), consists of delivery of compounds linked to radio-emitter particles which end up in hepatic end-arterioles or show affinity for the neoplasm itself, allowing localised delivery of doses beyond 120 Gy...
October 2012: Cancer Treatment Reviews
Christian Toso, Gilles Mentha, Norman M Kneteman, Pietro Majno
In the treatment of hepatocellular carcinomas, therapies such as trans-arterial chemo-embolisation, trans-arterial radioembolisation, percutaneous ethanol injection and radio-frequency ablation can decrease the size (and overall viability) of the tumours, thus potentially increasing the proportion of patients qualifying for resection and transplantation. While the use of such downstaging therapies is straightforward when resection is the aim, in a similar way to other neo-adjuvant treatments in the surgery of tumours that are too large or awkwardly placed to be primarily resected the issues related to transplantation are more complex...
June 2010: Journal of Hepatology
N Hamad, J Stephens, G F Maskell, S H Hussaini, H R Dalton
Endoscopic injection of N-butyl-2-cyanoacrylate combined with radio-opaque lipiodol is widely used to achieve haemostasis in bleeding gastric varices. We present a case of migration of injected cyanoacrylate, thrombus formation and subsequent septic embolisation.
November 2008: British Journal of Radiology
R A Sharma, H S Wasan, S B Love, S Dutton, J C Stokes, J L Smith
No abstract text is available yet for this article.
April 2008: Clinical Oncology: a Journal of the Royal College of Radiologists
Thomas Prot, Nermin Halkic, Nicolas Demartines
Surgery offer the only curative treatment for colorectal hepatic metastasis. Nowadays, five-year survival increases up to 58% in selected cases, due to the improvement and combination of chemotherapy, surgery and ablative treatment like embolisation, radio-frequency or cryoablation. Surgery should be integrated in a multi disciplinary approach and initial work-up must take in account patient general conditions, tumor location, and possible extra hepatic extension. Thus, a surgical resection may be performed immediately or after preparation with chemotherapy or selective portal embolization...
June 27, 2007: Revue Médicale Suisse
Philippe Lunetta, Ilkka Ojanpera, Antti Sajantila
A 42-year-old woman died from massive barium sulfate (BaSO(4)) lung embolism after a balloon catheter intended for elective colonography was inserted into her vagina. The vaginal insertion of the balloon catheter caused a bilateral laceration of the vaginal wall which was followed by penetration of BaSO(4) into the afferent veins and massive pulmonary embolism. Fluoroscopy performed during the fatal events and post-mortem X-rays revealed a radio-opaque substance in the vagina and uterus, the pelvic vessels and the vena cava, the right heart chambers, the lungs, and the kidneys...
October 25, 2007: Forensic Science International
M Bock, R Umathum, S Zuehlsdorff, S Volz, C Fink, P Hallscheidt, H Zimmermann, W Nitz, W Semmler
At present, interventional procedures, such as stent placement, are performed under X-ray image guidance. Unfortunately with X-ray imaging, both patient and interventionalist are exposed to ionising radiation. Furthermore, X-ray imaging is lacking soft tissue contrast and is not capable of true 3-D displays of either interventional device or tissue morphology. Magnetic resonance imaging (MRI) offers excellent soft tissue contrast, 3-D acquisition techniques, as well as rapid image acquisition and reconstruction...
2005: Radiation Protection Dosimetry
U Plöckinger, B Wiedenmann
Gastrointestinal neuroendocrine tumours are classified as functioning or non-functioning according to the presence or absence of a clinically evident hypersecretion syndrome. In foregut tumours the presence of autonomous hormone secretion and the respective hypersecretion syndrome indicate functionality. Abdominal ultrasound (US), computed tomography (CT), magnetic resonance tomography (MRT) and somatostatin receptor scintigraphy (SRS) are used for localisation of the primary tumour and metastasis. Invasive procedures such as endoscopic US, intraoperative US or intraoperative duodenal transillumination are useful to localise small (< 1 cm) tumours...
June 2004: Zeitschrift Für Gastroenterologie
M B Pitton, S Herber, P Raab, C Mönch, M Wunsch, J Schneider, F Schweden, G Otto, M Thelen
BACKGROUND: The purpose of this study was to evaluate safety and efficacy of a radiofrequency ablation system in clinical practice. METHODS: In 35 patients (age 63,9 +/- 12,6 years, range 22 - 83) a total of 65 liver tumors were percutaneously treated using a 200 watt radiofrequency generator and a LeVeen 4 cm array probe (RF3000, Boston Scientific). The interventions were performed under CT guidance in local anaesthesia and sedation. Adapted to the tumor size, the LeVeen Probe was repositioned during the procedure with an additional safety margin of 1 cm...
November 2003: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
G H Keng, F X Sundram
INTRODUCTION: Hepatocellular carcinoma (HCC) is a common malignancy worldwide. Surgical resection is generally accepted as the first choice treatment of HCC. Many non-surgical techniques have been developed and used for the treatment of inoperable HCC, with limited efficacy. This paper studies the role of radionuclide therapy in the treatment of inoperable HCC and in an adjuvant setting following curative resection of HCC. MATERIALS AND METHODS: Relevant articles published between 1980 and 2002 were reviewed...
July 2003: Annals of the Academy of Medicine, Singapore
Christoph Kampmann, Rita Brzezinska, Moji Abidini, Anke Wenzel, Carl-Friedrich Wippermann, Pirmin Habermehl, Markus Knuf, Reinhard Schumacher
BACKGROUND: It has been suggested that tungsten coils (TCs) may corrode 30 months after transcatheter embolisation (TCE). The aim of this study was to follow up children after TCE of aorto-pulmonary collaterals (APCs) with TCs. MATERIALS AND METHODS: Successful TCE of 99 APCs was performed in children using 152 TCs. Chest radiographs were obtained on the day after the procedure, after 3-6 months and 9-12 months, and yearly thereafter. RESULTS: Mean follow-up was 39...
December 2002: Pediatric Radiology
G H W Keng, F X Sundram, S W K Yu, S Somanesan, J Premaraj, C J Oon, R Kwok, M M Htoo
INTRODUCTION: In a minority of the cases, resection of hepatocellular carcinoma (HCC) is potentially curative but local recurrence is common. Adjuvant intra-arterial radio-conjugate therapy could potentially reduce the rate of local recurrence and increase disease-free and overall survival. However, in the majority of cases, treatment of HCC is largely palliative. A wide range of palliative treatment options are available and these include external radiation, hepatic intra-arterial chemo-embolisation, systemic chemotherapy and percutaneous ethanol injection...
May 2002: Annals of the Academy of Medicine, Singapore
H P Allgaier, P Deibert, G Becker, H E Blum
The therapeutic modalities in patients with hepatocellular carcinoma (HCC) depend on the number, size and location of the lesions as well as the stage of the underlying liver disease and the physical condition of the patients. In patients with small and solitary lesions resection, liver resection and in selected cases liver transplantation can be curative. In more advanced stages of the disease with larger or multiple lesions PEI and/or transarterial chemotherapy with or without embolisation (TACE or TAC) can slow the progression of the disease...
October 28, 1998: Praxis
H Douard, P Besse, J P Broustet
Delivery of a balloon-expandable stent was complicated by a systemic embolisation. The radio-opaque stent was lost in the descending aorta, but then removed by using a loop basket intravascular retriever set without any peripheral arterial complication.
June 1998: Catheterization and Cardiovascular Diagnosis
S Bhattacharya, A P Dhillon, M C Winslet, B R Davidson, N Shukla, S D Gupta, R Al-Mufti, K E Hobbs
Iodised oil (lipiodol) administered via the hepatic artery localises selectively in primary liver cell cancers (hepatocellular carcinomas or HCCs) for prolonged periods and has been used as a vehicle for cytotoxic agents. Despite clinical use, the mechanism of lipiodol retention by tumours has remained unclear, embolisation of oil droplets in the tumour vasculature being the prevailing hypothesis. We have investigated the role of tumour and endothelial cells in lipiodol retention. Human liver tumour (Hep G2) cells and human umbilical vein endothelial cells in culture were exposed to lipiodol...
April 1996: British Journal of Cancer
A M Granov, V N Polysalov, P G Tarazov, K V Prozorovskiĭ
A spectrum of roentgenoendovascular and percutaneous procedures of hepatic hemangioma treatment is considered for situations in which resection of the liver is not justified. Stage I of therapy involved embolisation of hepatic artery and its branches. At stage II, ultrasonography and roentgenoscopy-controlled aiming percutaneous puncture and sclerosation of hemangioma were conducted. Said procedure was used in treatment of 12 patients. The results were evaluated using scintigraphy, ultrasonography, computed tomography and aiming puncture biopsies...
1995: Voprosy Onkologii
F P Rocher, I Sentenac, C Berger, I Marquis, P Romestaing, J P Gerard
From 10/1989 to 12/1992, 135 patients were treated, in Lyon, by Stereotactic Radiosurgery (RS) +/- External beam Radiotherapy (EBRT). Indications were AVMs or tumours that could not be cured by embolisation or/and surgery and are not larger than 30 to 35 mm. Lesions received 15 to 20 Gy (70% isodose) in one course. Among the 42 AVMs, only one rebled 6 months after RS and 9/15 had clinical improvement. Thirty-one had a radiological follow-up of 4 to 29 months after RS. Ten were totally obliterated, seven regressed more than 80% and six had a reduction of 50 to 80% of their AVM...
1995: Acta Neurochirurgica. Supplement
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