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https://www.readbyqxmd.com/read/29903696/types-and-frequency-of-infusion-pump-alarms-protocol-for-a-retrospective-data-analysis
#1
Kevin R Glover, Rachel R Vitoux, Catherine Schuster, Christopher R Curtin
BACKGROUND: The variety of alarms from all types of medical devices has increased from 6 to 40 in the last three decades, with today's most critically ill patients experiencing as many as 45 alarms per hour. Alarm fatigue has been identified as a critical safety issue for clinical staff that can lead to potentially dangerous delays or nonresponse to actionable alarms, resulting in serious patient injury and death. To date, most research on medical device alarms has focused on the nonactionable alarms of physiological monitoring devices...
June 14, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29883535/strategies-for-managing-smart-pump-alarm-and-alert-fatigue-a-narrative-review
#2
Parth K Shah, Jamie Irizarry, Sean O'Neill
Although smart infusion pumps are intended to prevent medication errors by alerting users about doses that exceed set thresholds, a large number of clinically insignificant alarms and alerts create the potential for alert and alarm fatigue. We searched the PubMed, Scopus, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases for peer-reviewed literature (January 1, 2004-August 31, 2017) on managing smart pump alerts, alarms, and related fatigue. Twenty-nine articles that met the inclusion criteria were reviewed and organized into themes...
June 8, 2018: Pharmacotherapy
https://www.readbyqxmd.com/read/29867659/blue-enriched-light-enhances-alertness-but-impairs-accurate-performance-in-evening-chronotypes-driving-in-the-morning
#3
Beatriz Rodríguez-Morilla, Juan A Madrid, Enrique Molina, José Pérez-Navarro, Ángel Correa
Attention maintenance is highly demanding and typically leads to vigilance decrement along time on task. Therefore, performance in tasks involving vigilance maintenance for long periods, such as driving, tends to deteriorate over time. Cognitive performance has been demonstrated to fluctuate over 24 h of the day (known as circadian oscillations), thus showing peaks and troughs depending on the time of day (leading to optimal and suboptimal times of day, respectively). Consequently, vigilance decrements are more pronounced along time on task when it is performed at suboptimal times of day...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29860362/the-influence-of-social-modeling-gender-and-empathy-on-treatment-side-effects
#4
Kate Faasse, Bryony Parkes, James Kearney, Keith J Petrie
Background: Social modeling has the capacity to shape treatment outcomes, including side effects. Purpose: This study investigated the influence of social modeling of treatment side effects, gender, and participant empathy, on side effects of a placebo treatment. Methods: Ninety-six participants (48 females) completed a study purportedly investigating the influence of modafinil (actually placebo) on alertness and fatigue. The participants were randomly seated with a male or female confederate and saw this confederate report experiencing side effects or no side effects...
May 31, 2018: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/29813099/preventing-dispensing-errors-by-alerting-for-drug-confusions-in-the-pharmacy-information-system-a-survey-of-users
#5
Zizi Campmans, Arianne van Rhijn, René M Dull, Jacqueline Santen-Reestman, Katja Taxis, Sander D Borgsteede
INTRODUCTION: Drug confusion is thought to be the most common type of dispensing error. Several strategies can be implemented to reduce the risk of medication errors. One of these are alerts in the pharmacy information system. OBJECTIVE: To evaluate the experiences of pharmacists and pharmacy technicians with alerts for drug name and strength confusion. METHODS: In May 2017, a cross-sectional survey of pharmacists and pharmacy technicians was performed in community pharmacies in the Netherlands using an online questionnaire...
2018: PloS One
https://www.readbyqxmd.com/read/29787295/alertness-and-psychomotor-performance-levels-of-marine-pilots-on-an-irregular-work-roster
#6
Philippe Boudreau, Sylvain Lafrance, Diane B Boivin
Fatigue is recognized as an important safety concern in the transportation industry. In this study, our goal was to investigate how circadian and sleep-wake dependent factors influence St-Lawrence River pilots' sleep-wake cycle, alertness and psychomotor performance levels at work. A total of 18 male St-Lawrence River ship pilots were recruited to a 16-21-day field study. Pilots' chronotype, sleepiness and insomnia levels were documented using standardized questionnaires. Their sleep-wake cycle was documented by a sleep-wake log and wrist-worn activity monitoring...
May 22, 2018: Chronobiology International
https://www.readbyqxmd.com/read/29766382/reduced-effectiveness-of-interruptive-drug-drug-interaction-alerts-after-conversion-to-a-commercial-electronic-health-record
#7
Adam Wright, Skye Aaron, Diane L Seger, Lipika Samal, Gordon D Schiff, David W Bates
BACKGROUND: Drug-drug interaction (DDI) alerts in electronic health records (EHRs) can help prevent adverse drug events, but such alerts are frequently overridden, raising concerns about their clinical usefulness and contribution to alert fatigue. OBJECTIVE: To study the effect of conversion to a commercial EHR on DDI alert and acceptance rates. DESIGN: Two before-and-after studies. PARTICIPANTS: 3277 clinicians who received a DDI alert in the outpatient setting...
May 15, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29716912/effect-of-dynamic-light-application-on-cognitive-performance-and-well-being-of-intensive-care-nurses
#8
EDITORIAL
Koen S Simons, Enzio R K Boeijen, Marlies C Mertens, Paul Rood, Cornelis P C de Jager, Mark van den Boogaard
BACKGROUND: Exposure to bright light has alerting effects. In nurses, alertness may be decreased because of shift work and high work pressure, potentially reducing work performance and increasing the risk for medical errors. OBJECTIVES: To determine whether high-intensity dynamic light improves cognitive performance, self-reported depressive signs and symptoms, fatigue, alertness, and well-being in intensive care unit nurses. METHODS: In a single-center crossover study in an intensive care unit of a teaching hospital in the Netherlands, 10 registered nurses were randomly divided into 2 groups...
May 2018: American Journal of Critical Care: An Official Publication, American Association of Critical-Care Nurses
https://www.readbyqxmd.com/read/29707422/modafinil-for-the-improvement-of-patient-outcomes-following-traumatic-brain-injury
#9
REVIEW
Amne Borghol, Michael Aucoin, Ifeanyichukwu Onor, Dana Jamero, Fadi Hawawini
Objective : The authors sought to assess the literature evidence on the efficacy of modafinil use in patients with fatigue or excessive daytime sleepiness (EDS) secondary to traumatic brain injury (TBI). Method of Research : A literature search of Medline and PubMed was performed using the EBSCOhost database. Primary literature, observational studies, meta-analyses, case reports, and systematic reviews were assessed for content regarding modafinil and psychostimulant use in patients with TBI. Of the 23 articles collected, three randomized, controlled studies, three observational studies, one case report, and two systematic reviews gave a description of modafinil use in TBI patients...
April 1, 2018: Innovations in Clinical Neuroscience
https://www.readbyqxmd.com/read/29680419/a-randomised-controlled-trial-of-bright-light-therapy-and-morning-activity-for-adolescents-and-young-adults-with-delayed-sleep-wake-phase-disorder
#10
C Richardson, N Cain, K Bartel, G Micic, B Maddock, M Gradisar
A randomised controlled trial evaluated bright light therapy and morning activity for the treatment of Delayed Sleep-Wake Phase Disorder (DSWPD) in young people. 60 adolescents and young adults (range = 13-24 years, mean = 15.9 ± 2.2 y, 63% f) diagnosed with DSWPD were randomised to receive three weeks of post-awakening Green Bright Light Therapy (∼507 nm) and Sedentary Activity (sitting, watching TV), Green Bright Light Therapy and Morning Activity (standing, playing motion-sensing videogame), Red Light Therapy (∼643 nm) and Sedentary Activity or Red Light Therapy and Morning Activity...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29672521/acceptance-and-barriers-pertaining-to-a-general-practice-decision-support-system-for-multiple-clinical-conditions-a-mixed-methods-evaluation
#11
Derk L Arts, Stephanie K Medlock, Henk C P M van Weert, Jeremy C Wyatt, Ameen Abu-Hanna
BACKGROUND: Many studies have investigated the use of clinical decision support systems as a means to improve care, but have thus far failed to show significant effects on patient-related outcomes. We developed a clinical decision support system that attempted to address issues that were identified in these studies. The system was implemented in Dutch general practice and was designed to be both unobtrusive and to respond in real time. Despite our efforts, usage of the system was low...
2018: PloS One
https://www.readbyqxmd.com/read/29623186/trigger-alerts-associated-with-laboratory-abnormalities-on-identifying-potentially-preventable-adverse-drug-events-in-the-intensive-care-unit-and-general-ward
#12
Mitchell S Buckley, Jeffrey R Rasmussen, Dale S Bikin, Emily C Richards, Andrew J Berry, Mark A Culver, Ryan M Rivosecchi, Sandra L Kane-Gill
Background: Medication safety strategies involving trigger alerts have demonstrated potential in identifying drug-related hazardous conditions (DRHCs) and preventing adverse drug events in hospitalized patients. However, trigger alert effectiveness between intensive care unit (ICU) and general ward patients remains unknown. The objective was to investigate trigger alert performance in accurately identifying DRHCs associated with laboratory abnormalities in ICU and non-ICU settings. Methods: This retrospective, observational study was conducted at a university hospital over a 1-year period involving 20 unique trigger alerts aimed at identifying possible drug-induced laboratory abnormalities...
April 2018: Therapeutic Advances in Drug Safety
https://www.readbyqxmd.com/read/29609728/the-risk-of-fatigue-and-sleepiness-in-the-ridesharing-industry-an-american-academy-of-sleep-medicine-position-statement
#13
Michael Berneking, Ilene M Rosen, Douglas B Kirsch, Ronald D Chervin, Kelly A Carden, Kannan Ramar, R Nisha Aurora, David A Kristo, Raman K Malhotra, Jennifer L Martin, Eric J Olson, Carol L Rosen, James A Rowley, Indira Gurubhagavatula
The ridesharing-or ride-hailing-industry has grown exponentially in recent years, transforming quickly into a fee-for-service, unregulated taxi industry. While riders are experiencing the benefits of convenience and affordability, two key regulatory and safety issues deserve consideration. First, individuals who work as drivers in the ridesharing industry are often employed in a primary job, and they work as drivers during their "off" time. Such a schedule may lead to driving after extended periods of wakefulness or during nights, both of which are factors that increase the risk of drowsy driving accidents...
April 15, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29607220/remember-the-drive-home-an-assessment-of-emergency-providers-sleep-deficit
#14
Brian A Ferguson, Hugh W Shoff, Jennifer E McGowan, Martin R Huecker
Objective: Sleep deprivation decreases work performance and predisposes workers to deleterious health outcomes. We sought to evaluate sleep hygiene and fatigue among emergency physicians. Methods: In March-June 2016, physicians and residents at an academic emergency medicine program were invited to complete a survey evaluating sleep and alertness. Results: Six attending physicians and 26 residents completed the survey. Among six personal priorities, sleep ranked fourth behind family, work, and leisure...
2018: Emergency Medicine International
https://www.readbyqxmd.com/read/29599299/identification-of-patients-expected-to-benefit-from-electronic-alerts-for-acute-kidney-injury
#15
Aditya Biswas, Chirag R Parikh, Harold I Feldman, Amit X Garg, Stephen Latham, Haiqun Lin, Paul M Palevsky, Ugochukwu Ugwuowo, F Perry Wilson
BACKGROUND AND OBJECTIVES: Electronic alerts for heterogenous conditions such as AKI may not provide benefit for all eligible patients and can lead to alert fatigue, suggesting that personalized alert targeting may be useful. Uplift-based alert targeting may be superior to purely prognostic-targeting of interventions because uplift models assess marginal treatment effect rather than likelihood of outcome. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This is a secondary analysis of a clinical trial of 2278 adult patients with AKI randomized to an automated, electronic alert system versus usual care...
March 29, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29571975/asleep-at-the-automated-wheel-sleepiness-and-fatigue-during-highly-automated-driving
#16
Tobias Vogelpohl, Matthias Kühn, Thomas Hummel, Mark Vollrath
Due to the lack of active involvement in the driving situation and due to monotonous driving environments drivers with automation may be prone to become fatigued faster than manual drivers (e.g. Schömig et al., 2015). However, little is known about the progression of fatigue during automated driving and its effects on the ability to take back manual control after a take-over request. In this driving simulator study with Nö=ö60 drivers we used a three factorial 2ö×ö2ö×ö12 mixed design to analyze the progression (12ö×ö5ömin; within subjects) of driver fatigue in drivers with automation compared to manual drivers (between subjects)...
March 20, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29557078/a-double-blind-placebo-controlled-phase-ii-study-to-determine-the-efficacy-safety-tolerability-and-pharmacokinetics-of-a-controlled-release-cr-formulation-of-mazindol-in-adults-with-dsm-5-attention-deficit-hyperactivity-disorder-adhd
#17
Tim L Wigal, Jeffrey H Newcorn, Nelson Handal, Sharon B Wigal, Ioulietta Mulligan, Virginia Schmith, Eric Konofal
BACKGROUND: Mazindol is under investigation for the treatment of attention-deficit/hyperactivity disorder (ADHD) because of its alertness-enhancing properties. A novel controlled-release (CR) formulation of mazindol was developed to allow once-daily dosing. OBJECTIVE: The aim of this study was to evaluate the efficacy of mazindol CR in adults with ADHD. DESIGN: We conducted a randomized, double-blind, placebo-controlled 6-week trial. METHODS: Subjects diagnosed with ADHD using the Mini-International Neuropsychiatric Structured Interview (MINI) and with an ADHD Rating Scale, Diagnostic and Statistical Manual of Mental Disorders 5th Edition (ADHD-RS-DSM5) score ≥ 28 were randomized to receive placebo or 1-3 mg/day of mazindol for 6 weeks...
March 2018: CNS Drugs
https://www.readbyqxmd.com/read/29549968/cognitive-flexibility-a-distinct-element-of-performance-impairment-due-to-sleep-deprivation
#18
K A Honn, J M Hinson, P Whitney, H P A Van Dongen
In around-the-clock operations, reduced alertness due to circadian misalignment and sleep loss causes performance impairment, which can lead to catastrophic errors and accidents. There is mounting evidence that performance on different tasks is differentially affected, but the general principles underlying this differentiation are not well understood. One factor that may be particularly relevant is the degree to which tasks require executive control, that is, control over the initiation, monitoring, and termination of actions in order to achieve goals...
March 14, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29549745/exploring-the-effects-of-mental-and-muscular-fatigue-in-soccer-players-performance
#19
Diogo Coutinho, Bruno Gonçalves, Del P Wong, Bruno Travassos, Aaron J Coutts, Jaime Sampaio
This study examined the effects of induced mental and muscular fatigue on soccer players' physical activity profile and collective behavior during small-sided games (SSG). Ten youth soccer players performed a 5vs5 SSG under three conditions: a) control, playing without any previous activity; b) muscular fatigue, playing after performing a repeated change-of-direction task; c) mental fatigue, playing after completing a 30 min Stroop color-word task. Players' positional data was used to compute time-motion and tactical-related variables...
April 2018: Human Movement Science
https://www.readbyqxmd.com/read/29514353/the-value-of-monitoring-clinical-decision-support-interventions
#20
Eileen Yoshida, Shirley Fei, Karen Bavuso, Charles Lagor, Saverio Maviglia
BACKGROUND: Well-functioning clinical decision support (CDS) can facilitate provider workflow, improve patient care, promote better outcomes, and reduce costs. However, poorly functioning CDS may lead to alert fatigue, cause providers to ignore important CDS interventions, and increase provider dissatisfaction. OBJECTIVE: The purpose of this article is to describe one institution's experience in implementing a program to create and maintain properly functioning CDS by systematically monitoring CDS firing rates and patterns...
January 2018: Applied Clinical Informatics
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