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https://www.readbyqxmd.com/read/27919396/think-time-a-novel-approach-to-analysis-of-clinicians-behavior-after-reduction-of-drug-drug-interaction-alerts
#1
Richard Schreiber, Julia A Gregoire, Jacob E Shaha, Steven H Shaha
OBJECTIVES: Pharmacologic interaction alerting offers the potential for safer medication prescribing, but research reveals persistent concerns regarding alert fatigue. Research studies have tried various strategies to resolve this problem, with low overall success. We examined the effects of targeted alert reduction on clinician behavior in a resource constrained hospital. METHODS: A physician and a pharmacy informaticist reduced alert levels of several drug-drug interactions (DDI) that clinicians almost always overrode with approval from and knowledge of the medical staff...
January 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/27893483/game-times-and-higher-winning-percentages-of-west-coast-teams-of-the-national-football-league-correspond-with-reduced-prevalence-of-regular-season-injury
#2
Allison J Brager, R Justin Mistovich
West coast teams of the National Football League (NFL) are more statistically likely to win home night games against east coast opponents. The alignment of game times with daily rhythms of alertness is thought to contribute to this advantage. The present study aims to determine if rates of turnovers and injuries during the regular season, putative measures of mental and physical fatigue, impact winning percentages. Regular season schedules and rates of turnovers for each of the thirty-two teams were obtained from Pro-Football-Reference...
November 16, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27886139/research-on-the-relationship-between-reaction-ability-and-mental-state-for-online-assessment-of-driving-fatigue
#3
Mengzhu Guo, Shiwu Li, Linhong Wang, Meng Chai, Facheng Chen, Yunong Wei
Background: Driving fatigue affects the reaction ability of a driver. The aim of this research is to analyze the relationship between driving fatigue, physiological signals and driver's reaction time. Methods: Twenty subjects were tested during driving. Data pertaining to reaction time and physiological signals including electroencephalograph (EEG) were collected from twenty simulation experiments. Grey correlation analysis was used to select the input variable of the classification model. A support vector machine was used to divide the mental state into three levels...
November 24, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27872407/fatigue-work-schedules-and-perceived-performance-in-bedside-care-nurses
#4
Knar Sagherian, Michael E Clinton, Huda Abu-Saad Huijer, Jeanne Geiger-Brown
Hospital nurses are expected to maintain optimal work performance; yet, fatigue can threaten safe practice and result in unfavorable patient outcomes. This descriptive cross-sectional study explored the association between fatigue, work schedules, and perceived work performance among nurses. The study sample included 77 bedside nurses who were mostly female, single, and between 20 and 29 years of age. The majority worked 8-hour shifts and overtime. Nurses who worked during off days reported significantly higher chronic fatigue compared with those nurses who took time off...
November 21, 2016: Workplace Health & Safety
https://www.readbyqxmd.com/read/27854492/research-use-of-monitor-watchers-in-hospitals-characteristics-training-and-practices
#5
Marjorie Funk, Halley Ruppel, Nancy Blake, JoAnne Phillips
Monitor watchers, or personnel whose job it is to watch the central cardiac monitor and alert clinicians of patient events, are used in many hospitals. Monitor watchers may be used to improve timely response to alarms and combat the effects of alarm fatigue. However, little research has been done on the use of monitor watchers, and their practices have not been well described. Therefore, the purpose of our study was to examine the use of monitor watchers and their characteristics, training, and practices. Participants were recruited to complete an online survey on monitor watcher practice via two professional nursing organizations...
November 2016: Biomedical Instrumentation & Technology
https://www.readbyqxmd.com/read/27851710/a-community-hospital-s-evaluation-of-alarm-management-safety-factors
#6
Emma Kurnat-Thoma, Kayuri Shah
BACKGROUND: The Joint Commission's 2014 National Patient Safety Goals required hospitals to evaluate alarm safety in 2014-2015 and implement alarm safety policies. OBJECTIVE: The aim of this study was to assess common alarm management safety factors in our 187-bed community hospital. METHODS: Two weeks' worth of IV pump report data was evaluated to characterize 33 IV pump alarm types. Hospital and IV pump noise was measured, and an alarm management nurse survey was conducted...
December 2016: Journal of Nursing Administration
https://www.readbyqxmd.com/read/27830233/health-informatics-in-developing-countries-a-review-of-unintended-consequences-of-it-implementations-as-they-affect-patient-safety-and-recommendations-on-how-to-address-them
#7
C Otero, A A Almerares, D Luna, A Marcelo, M Househ, H Mandirola
BACKGROUND: Patient safety concerns every healthcare organization. Adoption of Health information technology (HIT) appears to have the potential to address this issue, however unanticipated and undesirable consequences from implementing HIT could lead to new and more complex hazards. This could be particularly problematic in developing countries, where regulations, policies and implementations are few, less standandarized and in some cases almost non-existing. METHODS: Based on the available information and our own experience, we conducted a review of unintended consequences of HIT implementations, as they affect patient safety in developing countries...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27822925/national-rules-for-drug-drug-interactions-are-they-appropriate-for-tertiary-hospitals
#8
Insook Cho, Jae Ho Lee, Jinwook Choi, Hee Hwang, David W Bates
The application of appropriate rules for drug-drug interactions (DDIs) could substantially reduce the number of adverse drug events. However, current implementations of such rules in tertiary hospitals are problematic as physicians are receiving too many alerts, causing high override rates and alert fatigue. We investigated the potential impact of Korean national DDI rules in a drug utilization review program in terms of their severity coverage and the clinical efficiency of how physicians respond to them. Using lists of high-priority DDIs developed with the support of the U...
December 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27816011/sleep-alertness-and-alertness-management-among-commercial-airline-pilots-on-short-haul-and-long-haul-flights
#9
Mikael Sallinen, Maria Sihvola, Sampsa Puttonen, Kimmo Ketola, Antti Tuori, Mikko Härmä, Göran Kecklund, Torbjörn Åkerstedt
Airline pilots' sleep and on-duty alertness are important focus areas in commercial aviation. Until now, studies pertaining to this topic have mainly focused on specific characteristics of flights and thus a comprehensive picture of the matter is not well established. In addition, research knowledge of what airline pilots actually do to maintain their alertness while being on duty is scarce. To address these gaps in research knowledge, we conducted a field study on a representative sample of the airline pilots of a medium-sized airline...
November 2, 2016: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/27815527/development-and-application-of-a-clinical-microsystem-simulation-methodology-for-human-factors-based-research-of-alarm-fatigue
#10
Leo Kobayashi, John W Gosbee, Derek L Merck
OBJECTIVES: (1) To develop a clinical microsystem simulation methodology for alarm fatigue research with a human factors engineering (HFE) assessment framework and (2) to explore its application to the comparative examination of different approaches to patient monitoring and provider notification. BACKGROUND: Problems with the design, implementation, and real-world use of patient monitoring systems result in alarm fatigue. A multidisciplinary team is developing an open-source tool kit to promote bedside informatics research and mitigate alarm fatigue...
November 3, 2016: HERD
https://www.readbyqxmd.com/read/27813284/functional-connectivity-alterations-in-patients-with-chronic-hepatitis-c-virus-infection-a-multimodal-mri-study
#11
S Kharabian Masouleh, S Herzig, L Klose, E Roggenhofer, H Tenckhoff, T Kaiser, A Thöne-Otto, M Wiese, T Berg, M L Schroeter, D S Margulies, A Villringer
Chronic hepatitis C virus (HCV) infection is associated with fatigue and depression. Cognitive impairments are also reported in a smaller number of HCV-positive patients. Recent studies linked HCV to low-grade inflammation in brain. Here, we test the hypothesis that chronic HCV is associated with 3T-neuroimaging-derived grey matter volume (GMV) and functional connectivity alterations in a sample of chronic HCV (1b), without severe liver disease. Regional GMV and resting-state fMRI-derived eigenvector centrality (EC) were compared between 19 HCV-positive patients and 23 healthy controls (all females, 50-69 and 52-64 years, respectively), controlling for white matter hyperintensities and age...
November 4, 2016: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/27786335/how-physician-perspectives-on-e-prescribing-evolve-over-time-a-case-study-following-the-transition-between-ehrs-in-an-outpatient-clinic
#12
Erika L Abramson, Vaishali Patel, Elizabeth R Pfoh, Rainu Kaushal
BACKGROUND: Physicians are expending tremendous resources transitioning to new electronic health records (EHRs), with electronic prescribing as a key functionality of most systems. Physician dissatisfaction post-transition can be quite marked, especially initially. However, little is known about how physicians' experiences using new EHRs for e-prescribing evolve over time. We previously published a qualitative case study about the early physician experience transitioning from an older to a newer, more robust EHR, in the outpatient setting, focusing on their perceptions of the electronic prescribing functionality...
October 26, 2016: Applied Clinical Informatics
https://www.readbyqxmd.com/read/27784751/switching-from-inadequate-adjunctive-or-combination-treatment-options-to-brexpiprazole-adjunctive-to-antidepressant-an-open-label-study-on-the-effects-on-depressive-symptoms-and-cognitive-and-physical-functioning
#13
Maurizio Fava, Takao Okame, Yuki Matsushima, Pamela Perry, Emmanuelle Weiller, Ross A Baker
BACKGROUND: Approximately 50% of patients with major depressive disorder (MDD) do not respond adequately to their antidepressant treatment (ADT), underscoring the need for more effective treatment options. The objective of this study was to investigate the effect of adjunctive brexpiprazole on depressive symptoms in patients with MDD who were not responding to adjunctive or combination therapy of their current ADTs with several different classes of agents (NCT02012218). METHODS: In this 6-week, open-label, phase 3b study, patients with MDD who had an inadequate response to ≥1 adjunctive or combination therapy, in addition to history of ≥1 failure to monotherapy ADT, were switched to adjunctive brexpiprazole...
October 26, 2016: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27783210/attention-in-parkinson-s-disease-with-fatigue-evidence-from-the-attention-network-test
#14
Caterina Pauletti, Daniela Mannarelli, Nicoletta Locuratolo, Luca Pollini, Antonio Currà, Lucio Marinelli, Steno Rinalduzzi, Francesco Fattapposta
Fatigue is a non-specific symptom that is common in chronic diseases and represents one of the most disabling symptoms in Parkinson's disease. PD patients often experience cognitive deficits related above all to executive functions. The relationship between cognitive changes and fatigue in PD patients has not been explored in depth. The Attention Network Test (ANT) is a rapid, widely used test to measure the efficiency of three attentional networks, i.e., alerting, orienting, and executive, by evaluating reaction times (RTs) in response to visual stimuli...
October 25, 2016: Journal of Neural Transmission
https://www.readbyqxmd.com/read/27782288/development-of-a-standardized-rating-tool-for-drug-alerts-to-reduce-information-overload
#15
Barbara Pfistermeister, Brita Sedlmayr, Andrius Patapovas, Gerald Suttner, Ozan Tektas, Aleksey Tarkhov, Johannes Kornhuber, Martin F Fromm, Thomas Bürkle, Hans-Ulrich Prokosch, Renke Maas
BACKGROUND: A well-known problem in current clinical decision support systems (CDSS) is the high number of alerts, which are often medically incorrect or irrelevant. This may lead to the so-called alert fatigue, an overriding of alerts, including those that are clinically relevant, and underuse of CDSS in general. OBJECTIVES: The aim of our study was to develop and to apply a standardized tool that allows its users to evaluate the quality of system-generated drug alerts...
October 26, 2016: Methods of Information in Medicine
https://www.readbyqxmd.com/read/27777683/improving-patient-safety-by-combating-alert-fatigue
#16
EDITORIAL
Jess L Rush, Jamil Ibrahim, Kenneth Saul, Robert T Brodell
No abstract text is available yet for this article.
October 2016: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/27762159/experience-of-plastic-surgery-registrars-in-a-european-working-time-directive-compliant-rota
#17
Catherine de Blacam, Sean Tierney, Odhran Shelley
BACKGROUND: Surgical training requires exposure to clinical decision-making and operative experience in a supervised environment. It is recognised that learning ability is compromised when fatigued. The European Working Time Directive requires a decrease in working hours, but compliance reduces trainees' clinical exposure, which has profound implications for plastic surgery training. The aim of this study was to evaluate plastic surgery registrars' experience of an EWTD-compliant rota, and to examine its impact on patient care, education, and logbook activity...
October 20, 2016: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/27757540/impact-of-restless-legs-syndrome-in-patients-with-inflammatory-bowel-disease-on-sleep-fatigue-and-quality-of-life
#18
Katharina A Schindlbeck, Janek Becker, Felix Berger, Arne Mehl, Charlotte Rewitzer, Sarah Geffe, Peter M Koch, Jan C Preiß, Britta Siegmund, Jochen Maul, Frank Marzinzik
PURPOSE: Inflammatory bowel disease has been associated with neurological symptoms including restless legs syndrome. Here, we investigated the impact of restless legs syndrome in patients with inflammatory bowel disease on sleep, fatigue, mood, cognition, and quality of life. METHODS: Two groups of inflammatory bowel disease patients, with and without restless legs syndrome, were prospectively evaluated for sleep disorders, fatigue, daytime sleepiness, depression, anxiety, and health-related quality of life...
October 18, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27664174/avoiding-alert-fatigue-in-pulmonary-embolism-decision-support-a-new-method-to-examine-trigger-rates
#19
Anne Press, Sundas Khan, Lauren McCullagh, Andy Schachter, Salvatore Pardo, Nina Kohn, Thomas McGinn
No abstract text is available yet for this article.
September 23, 2016: Evidence-based Medicine
https://www.readbyqxmd.com/read/27649778/effects-of-a-single-oral-60-mg-caffeine-dose-on-attention-in-healthy-adult-subjects
#20
Micha Mm Wilhelmus, Justin L Hay, Rob Gja Zuiker, Pieter Okkerse, Christelle Perdrieu, Julien Sauser, Maurice Beaumont, Jeroen Schmitt, Joop Ma van Gerven, Beata Y Silber
Caffeine induces positive effects on sustained attention, although studies assessing the acute effects of low caffeine dose (<75 mg) on sustained attention are limited and use short-term tests. Therefore, we investigated the acute effects of a 60 mg dose of caffeine on sustained attention in tests lasting up to 45 minutes using 82 low or non-caffeine-consuming healthy male (n=41) and female (n=41) adults aged between 40 and 60 years. Vigilance was measured using Mackworth Clock test, Rapid Visual Information Processing Test, adaptive tracking test, saccadic eye movement and attention switch test...
September 20, 2016: Journal of Psychopharmacology
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