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Graziela Aparecida Nogueira de Almeida Ribeiro, Helenice Brizolla Giampietro, Lídia Barbieri Belarmino, Wilson Salgado-Júnior
Background: The psychologist who works in bariatric surgery has a role to receive, evaluate, prepare and educate the patient who will undergo the surgical procedure. Psychological evaluation becomes important in so far as allows us to obtain data on personal and familiar history and allow tracing of possible psychopathology. Aim: To collect data on psychological evaluations of patients in a bariatric surgery service of a public hospital in order to describe the psychological profile of patients in this service...
2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
Anna Kłak, Filip Raciborski, Edyta Krzych-Fałta, Dagmara Opoczyńska-Świeżewska, Jakub Szymański, Agnieszka Lipiec, Barbara Piekarska, Adam Sybilski, Aneta Tomaszewska, Bolesław Samoliński
INTRODUCTION: The aim of the study is to indicate the relation between the use of alternative medicine and the occurrence of allergic diseases in the Polish population of adults in the age of 20-44 years. Moreover the additional aim of the study is to define the relation between the sex, age and place of living and the use of alternative medicine. MATERIAL AND METHODS: The data from the project Epidemiology of Allergic Diseases in Poland (ECAP) has been used for analysis...
2016: Pneumonologia i Alergologia Polska
Fanny Sunden, Ishraq AlSadhan, Artem Y Lyubimov, Susanne Ressl, Helen Wiersma-Koch, Jamar Borland, Clayton L Brown, Tory A Johnson, Zorawar Singh, Daniel Herschlag
Naively one might have expected an early division between phosphate monoesterases and diesterases of the Alkaline Phosphatase (AP) superfamily. On the contrary, prior results and our structural and biochemical analyses of phosphate monoesterase PafA, from Chryseobacterium meningosepticum, indicate similarities to a superfamily phosphate diesterase [Xanthomonas citri Nucleotide Pyrophosphatase/Phosphodiesterase (NPP)] and distinct differences from the three metal ion AP superfamily monoesterase, from E. coli AP (EcAP)...
September 26, 2016: Journal of the American Chemical Society
Edyta Krzych-Fałta, Konrad Furmanczyk, Bolesław Samolinski, Barbara Piekarska, Piotr Samel-Kowalik, Agnieszka Lipiec, Filip Raciborski, Adam Sybilski
OBJECTIVE: The aim of this study was to estimate the reference values for nasal inspiratory flow in the study population in Poland as part of the project on Epidemiology of Allergic Diseases in Poland (ECAP). MATERIALS AND METHOD: The study subjects were a group of 4,137 people: 1,136 children aged 6-7 years (561 girls and 575 boys), 1,123 adolescents aged 13-14 years (546 girls, 577 boys) and 1,878 adults (1,145 women, 733 men), residing in seven large Polish cities...
September 2016: Annals of Agricultural and Environmental Medicine: AAEM
S Redana, A Sharp, H Lote, K Mohammed, E Papadimitraki, M Capelan, A Ring
OBJECTIVES: To determine the incidence and risk factors for thromboembolic events (TE) and febrile neutropenia (FN) in patients receiving systemic chemotherapy for early breast cancer (EBC). METHODS: 325 patients received FEC75, FEC100-T or ECaP for EBC in 2013. RESULTS: TE occurred in 7.4% and FN in 19.1% of patients. Risk factors for TE were: central venous catheter (p = 0.011). Risk factors for FN were: FEC100-T treatment versus FEC75 and ECaP (p ≤ 0...
August 25, 2016: Breast: Official Journal of the European Society of Mastology
Xin Luo, Ching-Chih Wu
In cochlear implants (CIs), standard partial tripolar (pTP) mode reduces current spread by returning a fraction of the current to two adjacent flanking electrodes within the cochlea. Symmetric electrode spanning (i.e., separating both the apical and basal return electrodes from the main electrode by one electrode) has been shown to increase the pitch of pTP stimuli, when the ratio of intracochlear return current was fixed. To explain the pitch increase caused by symmetric spanning in pTP mode, this study measured the electrical potentials of both standard and symmetrically spanned pTP stimuli on a main electrode EL8 in five CI ears using electrical field imaging (EFI)...
August 25, 2016: Journal of the Association for Research in Otolaryngology: JARO
Junyi Zhang, Zhixin Kang, Fen Wang
A Mg-Gd-Nd-Zn-Zr alloy was processed by equal channel angular pressing (ECAP) at 375°C. The grain size of Mg-Gd-Nd-Zn-Zr alloy was refined to ~2.5μm with the spherical precipitates (β1 phase) distributing in the matrix. The mechanical properties of ECAPed alloy were significantly improved as a result of the grain refinement and precipitation strengthening. The corrosion rate of the ECAPed magnesium alloy in simulated body fluid dramatically decreased from 0.236mm/a to 0.126mm/a due to the strong basal texture and refined microstructure...
November 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
Kara C Schvartz-Leyzac, Bryan E Pfingst
Electrically evoked compound action potential (ECAP) measures of peak amplitude, and amplitude-growth function (AGF) slope have been shown to reflect characteristics of cochlear health (primarily spiral ganglion density) in anesthetized cochlear-implanted guinea pigs. Likewise, the effect of increasing the interphase gap (IPG) in each of these measures also reflects SGN density in the implanted guinea pig. Based on these findings, we hypothesize that suprathreshold ECAP measures, and also how they change as the IPG is increased, have the potential to be clinically applicable in human subjects...
August 10, 2016: Hearing Research
Lachlan J Kelsey, Janet T Powell, Paul E Norman, Karol Miller, Barry J Doyle
Aneurysms of the common iliac artery (CIAA) are most commonly seen in association with an abdominal aortic aneurysm (AAA). Isolated CIAAs, in the absence of an AAA, are uncommon. Similar to AAAs, CIAA may develop intraluminal thrombus (ILT). As isolated CIAAs have a contralateral common iliac artery for comparison, they provide an opportunity to study the haemodynamic mechanisms behind ILT formation. In this study, we compared a large isolated CIAA and the contralateral iliac artery using computational fluid dynamics (CFD) to determine if haemodynamic metrics correlate with the location of ILT...
August 10, 2016: International Journal for Numerical Methods in Biomedical Engineering
Jeffrey A Melvin, Lauren P Lashua, Megan R Kiedrowski, Guanyi Yang, Berthony Deslouches, Ronald C Montelaro, Jennifer M Bomberger
Antimicrobial-resistant infections are an urgent public health threat, and development of novel antimicrobial therapies has been painstakingly slow. Polymicrobial infections are increasingly recognized as a significant source of severe disease and also contribute to reduced susceptibility to antimicrobials. Chronic infections also are characterized by their ability to resist clearance, which is commonly linked to the development of biofilms that are notorious for antimicrobial resistance. The use of engineered cationic antimicrobial peptides (eCAPs) is attractive due to the slow development of resistance to these fast-acting antimicrobials and their ability to kill multidrug-resistant clinical isolates, key elements for the success of novel antimicrobial agents...
May 2016: MSphere
Miquel de la Torre Villalobos, Luis Miguel Martin-López, María Isabel Fernández Sanmartín, Elena Pujals Altes, Silvia Gasque Llopis, Santiago Batlle Vila, Victor Pérez-Solá, Patricia Novo Navarro, Isabel Gómez Simón, Cristina Fresno González, Ester Camprodon Rosanas, Antonio Bulbena Vilarrasa
BACKGROUND: Cardiovascular and metabolic monitoring of patients on antipsychotic medication is essential. This becomes more important in those of paediatric age, as they are more vulnerable, and also because prescriptions of this kind of drugs are still increasing. AIM: To evaluate the monitoring of cardiovascular and metabolic risk factors in a group of children and young people on antipsychotic medication. METHOD: A descriptive cross-sectional study was conducted in which a group of 220 patients aged 8-17 years, diagnosed with a mental disorder and on antipsychotic treatment...
June 9, 2016: Revista de Psiquiatrí́a y Salud Mental
F Christov, P Munder, L Berg, H Bagus, S Lang, D Arweiler-Harbeck
INTRODUCTION: Electric compound action potentials (ECAPs) provide information about the nerve's and device's function in and after cochlear implantation. In general, lower ECAP values are expected to generate better results. Aim was an analysis of ECAPs in the course of time as a function of the patient's age and electrode design. PATIENTS AND METHODS: Between 2008 and 2013, 168 patients of eight defined age groups were included into the investigation. NRTs were measured intraoperatively, after 6 and after 12months...
June 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
Alessandro Scorpecci, Alessandra D'Elia, Paolo Malerba, Italo Cantore, Patrizia Consolino, Franco Trabalzini, Gaetano Paludetti, Nicola Quaranta
In uncooperative patients, electrical compound action potential (ECAP) thresholds are reliable in predicting T-levels, but are not in determining the C-level profile. The present study aims to assess if the C-level profile can be predicted by a new objective procedure (C-NRT) which uses the amplitude growth function (AGF) and is based on the assumption that equal ECAP amplitudes elicit equal loudness percepts. This is a correlational study conducted in five tertiary care referral hospitals with 21 post-lingually deaf adult cochlear implant users...
May 30, 2016: European Archives of Oto-rhino-laryngology
Lauren P Lashua, Jeffrey A Melvin, Berthony Deslouches, Joseph M Pilewski, Ronald C Montelaro, Jennifer M Bomberger
OBJECTIVES: Chronic infections with the opportunistic pathogen Pseudomonas aeruginosa are responsible for the majority of the morbidity and mortality in patients with cystic fibrosis (CF). While P. aeruginosa infections may initially be treated successfully with standard antibiotics, chronic infections typically arise as bacteria transition to a biofilm mode of growth and acquire remarkable antimicrobial resistance. To address the critical need for novel antimicrobial therapeutics that can effectively suppress chronic bacterial infections in challenging physiological environments, such as the CF lung, we have rationally designed a de novo engineered cationic antimicrobial peptide, the 24-residue WLBU2, with broad-spectrum antibacterial activity for pan-drug-resistant P...
August 2016: Journal of Antimicrobial Chemotherapy
Harkamaljot Kandail, Mohamad Hamady, Xiao Yun Xu
PURPOSE: To quantify the hemodynamic impact of a flared renal stent on the performance of fenestrated stent-grafts (FSGs) by analyzing flow patterns and wall shear stress-derived parameters in flared and nonflared FSGs in different physiologic scenarios. METHODS: Hypothetical models of FSGs were created with and without flaring of the proximal portion of the renal stent. Flared FSGs with different dilation angles and protrusion lengths were examined, as well as a nonplanar flared FSG to account for lumbar curvature...
October 2016: Journal of Endovascular Therapy
Agnieszka Witecka, Aleksandra Bogucka, Akiko Yamamoto, Kristián Máthis, Tomáš Krajňák, Jakub Jaroszewicz, Wojciech Święszkowski
In vitro degradation behavior of squeeze cast (CAST) and equal channel angular pressed (ECAP) ZM21 magnesium alloy (2.0wt% Zn-0.98wt% Mn) was studied using immersion tests up to 4w in three different biological environments. Hanks' Balanced Salt Solution (Hanks), Earle's Balanced Salt Solution (Earle) and Eagle minimum essential medium supplemented with 10% (v/v) fetal bovine serum (E-MEM+10% FBS) were used to investigate the effect of carbonate buffer system, organic compounds and material processing on the degradation behavior of the ZM21 alloy samples...
August 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
Wendy A M H Thijssen, Nicole Kraaijvanger, Dennis G Barten, Marleen L M Boerma, Paul Giesen, Michel Wensing
BACKGROUND: The Netherlands has a well-developed primary care system, which increasingly collaborates with hospital emergency departments (EDs). In this setting, insight into crowding in EDs is limited. This study explored links between patients' ED Length of Stay (LOS) and their care pathways. METHODS: Observational multicenter study of 7000 ED patient records from 1 February 2013. Seven EDs spread over the Netherlands, representing overall Dutch EDs, were included...
2016: BMC Health Services Research
Akinori Kashio, Viral D Tejani, Rachel A Scheperle, Carolyn J Brown, Paul J Abbas
In this study we measured the electrically evoked compound action potential (ECAP) from different recording electrodes in the cochlea. Under the assumption that different response latencies may be the result of differences in the neural population contributing to the response, we assessed the relationship between neural response latency and spread of excitation. First, we evaluated changes in N1 latency when the recording electrode site was varied. Second, we recorded channel interaction functions using a forward masking technique but with recording electrodes at different intracochlear locations...
2016: Audiology & Neuro-otology
Stefan B Strahl, Dyan Ramekers, Marjolijn M B Nagelkerke, Konrad E Schwarz, Philipp Spitzer, Sjaak F L Klis, Wilko Grolman, Huib Versnel
The electrically evoked compound action potential (eCAP) is a routinely performed measure of the auditory nerve in cochlear implant users. Using a convolution model of the eCAP, additional information about the neural firing properties can be obtained, which may provide relevant information about the health of the auditory nerve. In this study, guinea pigs with various degrees of nerve degeneration were used to directly relate firing properties to nerve histology. The same convolution model was applied on human eCAPs to examine similarities and ultimately to examine its clinical applicability...
2016: Advances in Experimental Medicine and Biology
Berthony Deslouches, Mary L Hasek, Jodi K Craigo, Jonathan D Steckbeck, Ronald C Montelaro
We previously reported a series of de novo engineered cationic antibiotic peptides (eCAPs) consisting exclusively of arginine and tryptophan (WR) that display potent activity against diverse multidrug-resistant (MDR) bacterial strains. In this study, we sought to examine the influence of arginine compared to lysine on antibacterial properties by direct comparison of the WR peptides (8-18 residues) with a parallel series of engineered peptides containing only lysine and tryptophan. WR and WK series were compared for antibacterial activity by bacterial killing and growth inhibition assays and for mechanism of peptide-bacteria interactions by surface plasmon resonance and flow cytometry...
June 2016: Journal of Medical Microbiology
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