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endometrial biopsy preeclampsia

Roxana M Popovici, Miriam S Krause, Julia Jauckus, Ariane Germeyer, Ilma S Brum, Cecilia Garlanda, Thomas Strowitzki, Michael von Wolff
Human implantation is characterized by blastocyst attachment to endometrial epithelial cells followed by invasion of trophoblast into the maternal decidua. There has been an increasing amount of data linking higher levels of the pentraxin PTX3, a long pentraxin, to embryo implantation. PTX3 levels were found to be higher in patients with preeclampsia and intrauterine growth restriction, both conditions caused by faulty implantation. Furthermore, PTX3 knockout mice have reduced fertility due to cumulus oopherus malformation as well as implantation failure...
March 2008: Endocrinology
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