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Myocardial perfusion imaging

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https://www.readbyqxmd.com/read/29667014/automatically-computed-ecg-algorithm-for-the-quantification-of-myocardial-scar-and-the-prediction-of-mortality
#1
Patrick Badertscher, Ivo Strebel, Ursina Honegger, Nicolas Schaerli, Deborah Mueller, Christian Puelacher, Max Wagener, Roger Abächerli, Joan Walter, Zaid Sabti, Lorraine Sazgary, Stella Marbot, Jeanne du Fay de Lavallaz, Raphael Twerenbold, Jasper Boeddinghaus, Thomas Nestelberger, Nikola Kozhuharov, Tobias Breidthardt, Samyut Shrestha, Dayana Flores, Carmela Schumacher, Damian Wild, Stefan Osswald, Michael J Zellweger, Christian Mueller, Tobias Reichlin
BACKGROUND: Myocardial scar is associated with adverse cardiac outcomes. The Selvester QRS-score was developed to estimate myocardial scar from the 12-lead ECG, but its manual calculation is difficult. An automatically computed QRS-score would allow identification of patients with myocardial scar and an increased risk of mortality. OBJECTIVES: To assess the diagnostic and prognostic value of the automatically computed QRS-score. METHODS: The diagnostic value of the QRS-score computed automatically from a standard digital 12-lead was prospectively assessed in 2742 patients with suspected myocardial ischemia referred for myocardial perfusion imaging (MPI)...
April 17, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29667010/correction-to-adverse-effects-associated-with-regadenoson-myocardial-perfusion-imaging
#2
Efstathia Andrikopoulou, Fadi G Hage
Near the beginning of the first sentence in the second paragraph of the Introduction the parenthetical phrase should read: (single bolus of 400 mcg given intravenously, IV). The dosage of mcg was incorrectly published as 200.
April 17, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29663117/review-of-cardiovascular-imaging-in-the-journal-of-nuclear-cardiology-in-2017-part-2-of-2-myocardial-perfusion-imaging
#3
Fadi G Hage, Wael A AlJaroudi
In 2017, the Journal of Nuclear Cardiology published many high-quality articles. In this review, we will summarize a selection of these articles to provide a concise review of the main advancements that have recently occurred in the field. In the first article of this 2-part series, we focused on publications dealing with positron emission tomography, computed tomography, and magnetic resonance. This review will place emphasis on myocardial perfusion imaging using single-photon emission computed tomography summarizing advances in the field including prognosis, safety and tolerability, the impact of imaging on management, and the use of novel imaging protocols...
April 16, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29657046/impact-of-cardiac-hybrid-imaging-guided-patient-management-on-clinical-long-term-outcome
#4
Dominik C Benz, Lara Gaemperli, Christoph Gräni, Elia von Felten, Andreas A Giannopoulos, Michael Messerli, Ronny R Buechel, Oliver Gaemperli, Aju P Pazhenkottil, Philipp A Kaufmann
BACKGROUND: Although randomized trials have provided evidence for invasive fractional flow reserve to guide revascularization, evidence for non-invasive imaging is less well established. The present study investigated whether hybrid coronary computed tomography (CCTA)/single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) can identify patients who benefit from early revascularization compared to medical therapy. METHODS: This retrospective study consists of 414 patients referred for evaluation of known or suspected coronary artery disease (CAD) with CCTA/SPECT hybrid imaging...
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29652747/the-incremental-clinical-value-of-cardiac-hybrid-spect-cta-imaging-in-coronary-artery-disease
#5
Lin Qiu, Hui Tan, Dengfeng Cheng, Hongcheng Shi
Coronary artery disease (CAD) is a major cause of death worldwide. It is significantly important to assess the coronary lesion and its pathophysiological relevance comprehensively. Coronary computed tomography angiography (CTA) or myocardial perfusion imaging alone suffers from some limitations in the evaluation of CAD. Through the integration and spatial colocalization of complementary morphological and functional information, the results of published hybrid single-photon emission computed tomography (SPECT)/CTA studies in patients with CAD are promising for detecting functionally relevant coronary artery lesion and evaluating the relationship between diseased coronary artery, coronary artery anomaly, myocardial bridging, or coronary calcification and myocardial ischemia...
April 12, 2018: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29652661/combined-brain-and-heart-magnetic-resonance-imaging-in-systemic-vasculitides-fiction-or-real-need
#6
REVIEW
Sophie I Mavrogeni, George Kitas, Hildo J Lamb, Klearchos Psychoyios, Theodoros Dimitroulas, Loukia Koutsogeorgopoulou, Kyriaki Boki, Vasiliki Vartela, Genovefa Kolovou, George Markousis-Mavrogenis, Cees G Kallenberg, Loic Guillevin, Dimitrios Vassilopoulos
Systemic vasculitides (SVs) is a group of diseases characterised by inflammation/necrosis of the blood vessel wall in various organs. Simultaneous brain and heart involvement is a cause of increased morbidity/mortality in SV. We aimed to present evidence of concurrent brain/heart involvement in SV and the role of a combined brain/heart magnetic resonance imaging (MRI) in their risk stratification. Cerebral vasculitis (CV) can be presented as focal deficits, seizures, headache, neuropsychiatric manifestations or cognitive dysfunction and cardiovascular disease (CVD) as myocardial/vascular inflammation, perfusion/function defects and fibrosis...
April 10, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29651739/prognostic-utility-of-splenic-response-ratio-in-dipyridamole-pet-myocardial-perfusion-imaging
#7
Karan Bami, Shrankhala Tewari, Fadi Guirguis, Linda Garrard, Ann Guo, Alomgir Hossain, Terrence D Ruddy, Rob S B Beanlands, Robert A deKemp, Benjamin J W Chow, Girish Dwivedi
BACKGROUND: Cardiac magnetic resonance perfusion studies with adenosine stress have shown that splenic response can identify patients with inadequate pharmacologic stress. We investigate the incremental prognostic impact of splenic response ratio (SRR) in patients with normal Rubidium (Rb)-82 PET myocardial perfusion imaging (MPI). METHODS: Consecutive patients undergoing dipyridamole Rb-82 PET MPI for the evaluation of coronary artery disease were screened. Spleen and liver Rb-82 activity was measured and the SRR was calculated: SRR = (Spleen stress/Liver stress)/(Spleen rest/Liver rest)...
April 12, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29627741/effects-of-renal-sympathetic-denervation-on-myocardial-structure-function-and-perfusion-a-serial-cmr-study
#8
Sinny Delacroix, Ramesh G Chokka, Adam J Nelson, Dennis T Wong, Stephen Pederson, Joanne Nimmo, Adil Rajwani, Kerry Williams, Karen S Teo, Stephen G Worthley
BACKGROUND AND AIMS: Echocardiographic studies have shown improvements in cardiac indices associated with renal sympathetic denervation (RDN), however, the benefits on myocardial perfusion have never been assessed. This trial was designed to study the effects of RDN on myocardial perfusion using cardiac magnetic resonance (CMR) imaging. METHODS: A total of 14 patients with resistant hypertension were recruited for RDN and myocardial perfusion, alongside other CMR indices, was assessed at baseline and at 6 months...
March 10, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29625886/evaluation-of-staff-radiation-exposure-during-transthoracic-echocardiography-close-to-myocardial-perfusion-imaging
#9
Samia Massalha, Rachel Lugassi, Elyahu Raysberg, Amjad Koskosi, Gerson Lechtenberg, Ora Israel, John A Kennedy
BACKGROUND: Transthoracic echocardiography (TTE) and myocardial perfusion imaging (MPI) are used in cardiac patients. In this study the radiation exposure of sonographers performing TTE following MPI was evaluated. METHODS: Of 40 study patients, 30 underwent same-day99m Tc sestamibi MPI and TTE, while another 10 underwent only TTE. Patients who underwent both studies were divided into three groups: right-handed TTE performed by an echocardiographer and right- and left-handed TTE performed by a cardiac sonographer...
April 3, 2018: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29615162/myocardial-perfusion-imaging-the-gatekeeper-and-advisor
#10
EDITORIAL
Maseeh Uz Zaman, Nosheen Fatima
No abstract text is available yet for this article.
April 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29606367/t-max-is-a-sensitive-indicator-of-myocardial-ischaemia-under-adenosine-stress-as-determined-by-static-pet-imaging-a-study-in-a-porcine-model
#11
S Sui, Y Hou, Y Ma, Y Wang, M Yu, Y Yang, N Huang
AIM: To evaluate Tmax , defined as the time of residual function R(t) reaching its maximum, as an indicator of myocardial ischaemia and compare its efficacy with other computed tomography perfusion (CTP) parameters. MATERIALS AND METHODS: Eight Bama miniature pigs with 50-90% left anterior descending artery stenosis underwent adenosine stress myocardial CTP and13 NNH3 position-emission tomography (PET) perfusion imaging. Tmax , myocardial blood flow (MBF), myocardial blood volume (MBV), mean transit time (MTT), and time to peak (TTP) were calculated from CTP images...
March 29, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29603482/3d-image-fusion-of-whole-heart-dynamic-cardiac-mr-perfusion-and-late-gadolinium-enhancement-intuitive-delineation-of-myocardial-hypoperfusion-and-scar
#12
Jochen von Spiczak, Manoj Mannil, Sebastian Kozerke, Hatem Alkadhi, Robert Manka
BACKGROUND: Since patients with myocardial hypoperfusion due to coronary artery disease (CAD) with preserved viability are known to benefit from revascularization, accurate differentiation of hypoperfusion from scar is desirable. PURPOSE: To develop a framework for 3D fusion of whole-heart dynamic cardiac MR perfusion and late gadolinium enhancement (LGE) to delineate stress-induced myocardial hypoperfusion and scar. STUDY TYPE: Prospective feasibility study...
March 30, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29589207/do-we-really-need-to-look-at-volumetric-measurements-with-99m-tc-single-photon-emission-computed-tomography-spect-myocardial-perfusion-imaging
#13
EDITORIAL
Dominik C Benz, Andreas A Giannopoulos
No abstract text is available yet for this article.
March 27, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29589206/saline-push-improves-rubidium-82-pet-image-quality
#14
Jennifer M Renaud, Kai Yi Wu, Kimberly Gardner, May Aung, Rob S B Beanlands, Robert A deKemp
INTRODUCTION: Rubidium-82 (82 Rb) PET is used widely for myocardial perfusion imaging. The purpose of this study was to investigate if an additional saline-push following the82 Rb elution improves PET image quality. METHODS: 82 Rb PET scans were acquired with and without 26 mL saline-push in six patients as part of a clinical quality improvement program. Dynamic images were analyzed to measure the total activity delivered to the superior vena cava (SVC) and retained in the left ventricle (LV) myocardium...
March 27, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29578927/minimal-starting-time-of-data-reconstruction-for-qualitative-myocardial-perfusion-rubidium-82-positron-emission-tomography-imaging
#15
Joris D van Dijk, Eline D Huizing, Jorn A van Dalen, Jorik R Timmer, Pieter L Jager
OBJECTIVE: Qualitative positron emission tomography (PET) myocardial perfusion imaging (MPI) scans are reconstructed with a delay after an injection of rubidium-82 (Rb) to ensure blood pool clearance and sufficient left ventricle to myocardium contrast. Our aim was to derive the minimal starting time of data reconstruction (STDR) after an injection of Rb for which the diagnostic value and image quality remained unaffected. MATERIALS AND METHODS: We retrospectively included 23 patients who underwent rest-stress Rb PET MPI using 740 MBq...
March 23, 2018: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29576220/fusion-of-three-dimensional-echocardiographic-regional-myocardial-strain-with-cardiac-computed-tomography-for-noninvasive-evaluation-of-the-hemodynamic-impact-of-coronary-stenosis-in-patients-with-chest-pain
#16
Victor Mor-Avi, Mita B Patel, Francesco Maffessanti, Amita Singh, Diego Medvedofsky, S Javed Zaidi, Anuj Mediratta, Akhil Narang, Noreen Nazir, Nadjia Kachenoura, Roberto M Lang, Amit R Patel
BACKGROUND: Combined evaluation of coronary stenosis and the extent of ischemia is essential in patients with chest pain. Intermediate-grade stenosis on computed tomographic coronary angiography (CTCA) frequently triggers downstream nuclear stress testing. Alternative approaches without stress and/or radiation may have important implications. Myocardial strain measured from echocardiographic images can be used to detect subclinical dysfunction. The authors recently tested the feasibility of fusion of three-dimensional (3D) echocardiography-derived regional resting longitudinal strain with coronary arteries from CTCA to determine the hemodynamic significance of stenosis...
March 22, 2018: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29574494/motion-correction-and-its-impact-on-absolute-myocardial-blood-flow-measures-with-pet
#17
REVIEW
Marina Piccinelli, John R Votaw, Ernest V Garcia
PURPOSE OF REVIEW: Motion artifacts, due to cardiac and respiratory cycles, myocardial cardiac creep, or gross patient movements, have been extensively investigated in the context of relative myocardial perfusion imaging with SPECT and PET. These movements have been identified as a major source of errors in image quantification and diagnosis. Recently, as dynamic PET quantification for myocardial blood flow assessment has entered clinical practice, similar questions have arisen on the impact of motion on final blood flow values...
March 24, 2018: Current Cardiology Reports
https://www.readbyqxmd.com/read/29572594/blood-pool-and-tissue-phase-patient-motion-effects-on-82-rubidium-pet-myocardial-blood-flow-quantification
#18
Benjamin C Lee, Jonathan B Moody, Alexis Poitrasson-Rivière, Amanda C Melvin, Richard L Weinberg, James R Corbett, Edward P Ficaro, Venkatesh L Murthy
BACKGROUND: Patient motion can lead to misalignment of left ventricular volumes of interest and subsequently inaccurate quantification of myocardial blood flow (MBF) and flow reserve (MFR) from dynamic PET myocardial perfusion images. We aimed to identify the prevalence of patient motion in both blood and tissue phases and analyze the effects of this motion on MBF and MFR estimates. METHODS: We selected 225 consecutive patients that underwent dynamic stress/rest rubidium-82 chloride (82 Rb) PET imaging...
March 23, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29561994/current-practices-in-myocardial-perfusion-scintigraphy-in-brazil-and-adherence-to-the-iaea-recommendations-results-of-a-cross-sectional-study
#19
Carlos Vitor Braga Rodrigues, Anderson Oliveira, Christiane Cigagna Wiefels, Maurício de Souza Leão, Cláudio Tinoco Mesquita
BACKGROUND: Data on the current situation of nuclear medicine practices in cardiology in Brazil are scarce. The International Atomic Energy Agency (IAEA) has recommended eight "good practices" to minimize patients' ionizing radiation exposure during myocardial perfusion scintigraphy (MPS). OBJECTIVES: To assess the adoption of the eight good practices in MPS in Brazil. METHODS: Cross-sectional study with data obtained by use of a questionnaire...
February 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29556942/feasibility-of-myocardial-flow-reserve-prediction-without-the-use-of-dynamic-data-from-myocardial-perfusion-positron-emission-tomography
#20
Hidenobu Hashimoto, Yoshimitsu Fukushima, Shin-Ichiro Kumita, Takeshi Tomiyama, Tomonari Kiriyama
Quantification of myocardial flow reserve (MFR) provides diagnostic value for detection of cardiovascular artery disease. However, the common calculation method for MFR requires dynamic acquisition and specific software. The study aimed to predict coronary artery disease by simpler calculation of myocardial count without the use of dynamic data from13 N-ammonia myocardial perfusion positron emission tomography (MP-PET). This study included 40 consecutive patients suspected of ischemic heart disease and 7 healthy controls (34 men and 13 women, 66 ± 12 years)...
March 19, 2018: International Journal of Cardiovascular Imaging
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