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https://www.readbyqxmd.com/read/29037529/the-relationship-between-tobacco-smoke-exposure-and-airflow-obstruction-in-us-children-analysis-of-the-national-health-and-nutrition-examination-survey-2007-2012
#1
Stacey-Ann Whittaker Brown, Bian Liu, Emanuela Taioli
BACKGROUND: It has been difficult to determine the individual impact of pre and post-natal childhood tobacco smoke exposure (TSE) on childhood lung function, as children are often exposed to both. AIMS: To determine the association between current TSE, as measured by serum cotinine levels, and airflow obstruction (defined as the ratio of forced expiratory volume in one second and the forced vital capacity (FEV1/FVC) less than the lower limit of normal), while adjusting for self-reported prenatal TSE...
October 13, 2017: Chest
https://www.readbyqxmd.com/read/28987842/post-natal-management-of-myelomeningocele-outcome-with-a-multidisciplinary-team-experience
#2
P A Beuriat, I Poirot, F Hameury, A Szathmari, C Rousselle, I Sabatier, F Di Rocco, C Mottolese
INTRODUCTION: Myelomeningocele (MMC) is a complex neural tube defect. Few studies report the results of modern post-natal management. The goal of this study was to report the long term outcome of a multidisciplinary approach of MMC patients. MATERIALS AND METHODS: Forty-six MMC were included. Clinical status was evaluated prospectively. RESULTS: Mean follow-up was 8,1 years. The level of the malformation was sacral or lower lumbar (≤ L4) in 27 cases, higher lumbar (between L1 and L3) in 5 cases and thoracic in 14 cases...
October 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28972670/ultrasonographic-aspects-of-the-leontopithecus-gestation-lesson-1840-callitrichidae-primates
#3
Marcelline Santos Luz, Fabrício Delgado Vidal, Carlos Henrique Freitas Burity, Denise de Mello Bobány, Alcides Pissinatti
BACKGROUND: There is a concern about conservation of endangered species today. Among this species, the Leontopithecus (Lesson, 1840) is outstanding. Its population has been whirling reduced. So far the reproductive physiology of Leontopithecus has few studies, it is fundamental requisite to preserve this species. Obstetric sonography has become an essential method in reproductive management of primates. METHOD: This method is very helpful to detect early pregnancy and evaluate some deficiency of fetal growth...
October 3, 2017: Journal of Medical Primatology
https://www.readbyqxmd.com/read/28954035/preimplantation-genetic-diagnosis-associated-to-duchenne-muscular-dystrophy
#4
Bianca Bianco, Denise Maria Christofolini, Gabriel Seixas Conceição, Caio Parente Barbosa
Duchenne muscular dystrophy is the most common muscle disease found in male children. Currently, there is no effective therapy available for Duchenne muscular dystrophy patients. Therefore, it is essential to make a prenatal diagnosis and provide genetic counseling to reduce the birth of such boys. We report a case of preimplantation genetic diagnosis associated with Duchenne muscular dystrophy. The couple E.P.R., 38-year-old, symptomatic patient heterozygous for a 2 to 47 exon deletion mutation in DMD gene and G...
September 21, 2017: Einstein
https://www.readbyqxmd.com/read/28953269/small-for-gestational-age-prevalence-risk-factors-in-central-appalachian-states-with-mountain-top-mining
#5
Hamid Ferdosi, Steve H Lamm, Nana Ama Afari-Dwamena, Elisabeth Dissen, Rusan Chen, Ji Li, Manning Feinleib
OBJECTIVES: To identify risk factors for small-for-gestational age (SGA) for counties in central Appalachian states (Kentucky (KY), Tennessee (TN), Virginia (VA), and West Virginia (WV)) with varied coal mining activities. MATERIAL AND METHODS: Live birth certificate files (1990-2002) were used for obtaining SGA prevalence rates for mothers based on the coal mining activities of their counties of residence, mountain-top mining (MTM) activities, underground mining activities but no mountain-top mining activity (non-MTM), or having no mining activities (non-mining)...
September 27, 2017: International Journal of Occupational Medicine and Environmental Health
https://www.readbyqxmd.com/read/28946647/knowledge-attitude-and-practice-of-pregnant-women-towards-varicella-and-their-children-s-varicella-vaccination-evidence-from-three-distrcits-in-zhejiang-province-china
#6
Yu Hu, Yaping Chen, Ying Wang, Hui Liang
Background: The objectives of this study were to examine the knowledge, attitudes and practice (KAP) towards varicella and varicella vaccine (VarV) vaccination among pregnant women in three distrcits in Zhejiang Province, China. Methods: From 1 January to 31 March 2014, pregnant women with ≥12 gestational weeks were recruited and received a self-administrated questionnaire. The first dose of VarV (VarV1) vaccination status of children from present pregnancy was extracted at 24 months of age from Zhejiang provincial immunization information system (ZJIIS)...
September 24, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28902327/anxiety-in-pregnancy-prevalence-and-associated-factors
#7
Mônica Maria de Jesus Silva, Denismar Alves Nogueira, Maria José Clapis, Eliana Peres Rocha Carvalho Leite
OBJECTIVE: Evaluating the occurrence of anxiety in pregnant women and the factors associated with its occurrence; comparing the presence of anxiety in each gestational trimester. METHOD: A descriptive, correlational cross-sectional study. Data were collected from January to May 2013 using the Hospital Anxiety Subscale and a form composed of socioeconomic characterization; gestational anamnesis; life-changing habits and events; preexisting conditions and interpersonal relationships...
August 28, 2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28853439/u-s-epidemiology-of-cannabis-use-and-associated-problems
#8
Deborah S Hasin
This review provides an overview of the changing U.S. epidemiology of cannabis use and associated problems. Adults and adolescents increasingly view cannabis as harmless, and some can use cannabis without harm. However, potential problems include harms from pre-natal exposure and unintentional childhood exposure; decline in educational or occupational functioning after early adolescent use, and in adulthood, impaired driving and vehicle crashes; cannabis use disorders (CUD), cannabis withdrawal, and psychiatric comorbidity...
August 30, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28832758/risk-factors-for-syphilis-in-women-case-control-study
#9
Vilma Costa de Macêdo, Pedro Israel Cabral de Lira, Paulo Germano de Frias, Luciana Maria Delgado Romaguera, Silvana de Fátima Ferreira Caires, Ricardo Arraes de Alencar Ximenes
OBJECTIVE: To determine the sociodemographic, behavioral, and health care factors related to the occurrence of syphilis in women treated at public maternity hospitals. METHODS: This is a case-control study (239 cases and 322 controls) with women admitted to seven maternity hospitals in the municipality of Recife, Brazil, from July 2013 to July 2014. Eligible women were recruited after the result of the VDRL (Venereal Disease Research Laboratory) under any titration...
August 17, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28832755/assessment-in-the-primary-care-of-the-state-of-s%C3%A3-o-paulo-brazil-incipient-actions-in-sexual-and-reproductive-health
#10
Mariana Arantes Nasser, Maria Ines Battistella Nemes, Marta Campagnoni Andrade, Rogério Ruscitto do Prado, Elen Rose Lodeiro Castanheira
OBJECTIVE: The objective of this study is to assess performance in sexual and reproductive health of primary health care services of the Brazilian Unified Health System, in the State of São Paulo, Brazil. METHODS: An evaluative framework was built for sexual and reproductive health with the categorization of 99 indicators in three domains: sexual and reproductive health promotion (25), sexually transmitted infections/AIDS prevention and care (43), and reproductive health care (31)...
August 17, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28821223/maternal-nutrient-restriction-in-mid-to-late-gestation-influences-fetal-mrna-expression-in-muscle-tissues-in-beef-cattle
#11
Francois Paradis, Katie M Wood, Kendall C Swanson, Stephen P Miller, Brian W McBride, Carolyn Fitzsimmons
BACKGROUND: Manipulating maternal nutrition during specific periods of gestation can result in re-programming of fetal and post-natal development. In this experiment we investigated how a feed restriction of 85% compared with 140% of total metabolizable energy requirements, fed to cows during mid-to-late gestation, influences phenotypic development of fetuses and mRNA expression of growth (Insulin-Like Growth Factor family and Insulin Receptor (INSR)), myogenic (Myogenic Differentiation 1 (MYOD1), Myogenin (MYOG), Myocyte Enhancer Factor 2A (MEF2A), Serum Response Factor (SRF)) and adipogenic (Peroxisome Proliferator Activated Receptor Gamma (PPARG)) genes in fetal longissimus dorsi (LD) and semitendinosus (ST) muscle...
August 18, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28807864/reducing-diagnostic-turnaround-times-of-exome-sequencing-for-families-requiring-timely-diagnoses
#12
Aurélie Bourchany, Christel Thauvin-Robinet, Daphné Lehalle, Ange-Line Bruel, Alice Masurel-Paulet, Nolwenn Jean, Sophie Nambot, Marjorie Willems, Laetitia Lambert, Salima El Chehadeh-Djebbar, Elise Schaefer, Aurélia Jaquette, Judith St-Onge, Charlotte Poe, Thibaud Jouan, Martin Chevarin, Patrick Callier, Anne-Laure Mosca-Boidron, Nicole Laurent, Mathilde Lefebvre, Frédéric Huet, Nada Houcinat, Sébastien Moutton, Christophe Philippe, Frédéric Tran-Mau-Them, Antonio Vitobello, Paul Kuentz, Yannis Duffourd, Jean-Baptiste Rivière, Julien Thevenon, Laurence Faivre
BACKGROUND AND OBJECTIVE: Whole-exome sequencing (WES) has now entered medical practice with powerful applications in the diagnosis of rare Mendelian disorders. Although the usefulness and cost-effectiveness of WES have been widely demonstrated, it is essential to reduce the diagnostic turnaround time to make WES a first-line procedure. Since 2011, the automation of laboratory procedures and advances in sequencing chemistry have made it possible to carry out diagnostic whole genome sequencing from the blood sample to molecular diagnosis of suspected genetic disorders within 50 h...
August 12, 2017: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/28805477/estimated-exposures-to-perfluorinated-compounds-in-infancy-predict-attenuated-vaccine-antibody-concentrations-at-age-5-years
#13
Philippe Grandjean, Carsten Heilmann, Pal Weihe, Flemming Nielsen, Ulla B Mogensen, Amalie Timmermann, Esben Budtz-Jørgensen
Perfluorinated alkylate substances (PFASs) are highly persistent and may cause immunotoxic effects. PFAS-associated attenuated antibody responses to childhood vaccines may be affected by PFAS exposures during infancy, where breastfeeding adds to PFAS exposures. Of 490 members of a Faroese birth cohort, 275 and 349 participated in clinical examinations and provided blood samples at ages 18 months and 5 years. PFAS concentrations were measured at birth and at the clinical examinations. Using information on duration of breastfeeding, serum-PFAS concentration profiles during infancy were estimated...
December 2017: Journal of Immunotoxicology
https://www.readbyqxmd.com/read/28767925/autism-spectrum-disorders-an-updated-guide-for-genetic-counseling
#14
Karina Griesi-Oliveira, Andréa Laurato Sertié
Autism spectrum disorder is a complex and genetically heterogeneous disorder, which has hampered the identification of the etiological factors in each patient and, consequently, the genetic counseling for families at risk. However, in the last decades, the remarkable advances in the knowledge of genetic aspects of autism based on genetic and molecular research, as well as the development of new molecular diagnostic tools, have substantially changed this scenario. Nowadays, it is estimated that using the currently available molecular tests, a potential underlying genetic cause can be identified in nearly 25% of cases...
April 2017: Einstein
https://www.readbyqxmd.com/read/28718491/-hiv-aids-surveillance-among-pregnant-women-assessing-the-quality-of-the-available-information
#15
Maria Quitéria Batista Meirelles, Ana Karla Bezerra Lopes, Kenio Costa Lima
Objective: To analyze the quality of the information available in the Reportable Disease Information System (SINAN) regarding pregnant women with HIV/AIDS in the state of Rio Grande do Norte, Brazil, between 2007 and 2014. Method: The quality of information was analyzed based on completeness (percentage of fields containing values that were not null) of fields (sociodemographic information, epidemiologic maternal history, pre-natal care, and delivery) and on the existence of discrepancy between the data sources analyzed (Natal and Mossoró municipal departments of health, state department of health, and Unified Health System information database, DATASUS)...
December 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28702262/hemispheric-asymmetry-of-development-due-to-drug-exposure
#16
Harold W Gordon
BACKGROUND: A previous survey of the literature of fMRI brain activation for two risk factors, impulsivity and craving, for addiction were lateralized to the right and left hemispheres respectively. Most articles reported these findings without consideration of how lateral asymmetries might be relevant to understanding the underlying factors leading to addiction. OBJECTIVE: The current survey is intended to extend these observations by demonstrating hemispheric asymmetry of development due to pre-natal or adolescent/adult exposure to drugs of abuse...
2017: Journal of Systems and Integrative Neuroscience
https://www.readbyqxmd.com/read/28683116/persisting-fetal-clonotypes-influence-the-structure-and-overlap-of-adult-human-t-cell-receptor-repertoires
#17
Mikhail V Pogorelyy, Yuval Elhanati, Quentin Marcou, Anastasiia L Sycheva, Ekaterina A Komech, Vadim I Nazarov, Olga V Britanova, Dmitriy M Chudakov, Ilgar Z Mamedov, Yury B Lebedev, Thierry Mora, Aleksandra M Walczak
The diversity of T-cell receptors recognizing foreign pathogens is generated through a highly stochastic recombination process, making the independent production of the same sequence rare. Yet unrelated individuals do share receptors, which together constitute a "public" repertoire of abundant clonotypes. The TCR repertoire is initially formed prenatally, when the enzyme inserting random nucleotides is downregulated, producing a limited diversity subset. By statistically analyzing deep sequencing T-cell repertoire data from twins, unrelated individuals of various ages, and cord blood, we show that T-cell clones generated before birth persist and maintain high abundances in adult organisms for decades, slowly decaying with age...
July 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28677841/unexpected-haemophilia-despite-pre-natal-testing-a-combined-haemophilia-a-and-haemophilia-b-family
#18
Noémi B A Roy, Nicola Curry, David Keeling
No abstract text is available yet for this article.
October 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28619256/pre-natal-and-post-natal-environment-monitoring-to-prevent-non-alcoholic-fatty-liver-disease-development
#19
EDITORIAL
Anna Alisi, Pietro Vajro
No abstract text is available yet for this article.
May 24, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28562743/reproductive-aspects-and-knowledge-of-family-planning-among-women-with-acquired-immunodeficiency-syndrome
#20
Ivana Cristina Vieira de Lima, Maria da Conceição Dos Santos Oliveira Cunha, Gilmara Holanda da Cunha, Marli Teresinha Gimeniz Galvão
OBJECTIVE: To analyze the reproductive aspects and knowledge of family planning among women with Acquired Immunodeficiency Syndrome (AIDS). METHOD: Cross-sectional and descriptive study carried out from January to December, 2015, in the outpatient care of infectious disease unit in a hospital located in Fortaleza, Ceará. Data were collected through a form applied by interview in a private setting. RESULTS: 102 women participated in the study...
May 25, 2017: Revista da Escola de Enfermagem da U S P
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