keyword
https://read.qxmd.com/read/38482547/impact-of-the-covid-19-pandemic-on-the-rate-of-lower-limb-amputation-in-veterans
#21
JOURNAL ARTICLE
Kierra J Falbo, Nicole R Walker, Amber L Wacek, Juan E Cave, Matthew D Sauerbrey, Amy A Gravely, Mary E Matsumoto, John M Looft
BACKGROUND: The COVID-19 pandemic led to changes in health care, including postponement of nonurgent appointments. These changes, combined with overall decreased activity levels, may have placed individuals with vascular disease at increased risk for skin ulceration and amputation. OBJECTIVE: To determine the rates of lower limb amputation in Veterans due to complications of diabetes and/or vascular disease in the year following onset of the COVID-19 pandemic (March 2020-March 2021) compared to the previous 3 years (March 2017-March 2020)...
March 14, 2024: PM & R: the Journal of Injury, Function, and Rehabilitation
https://read.qxmd.com/read/38481376/incident-hiv-associated-wasting-low-weight-is-associated-with-nearly-doubled-mortality-risk-in-the-modern-art-era
#22
JOURNAL ARTICLE
Michael B Wohlfeiler, Rachel Palmieri Weber, Laurence Brunet, Javeed Siddiqui, Michael Harbour, Amy L Phillips, Brooke Hayward, Jennifer S Fusco, Ricky Hsu, Gregory P Fusco
HIV-associated wasting (HIVAW) is an under-appreciated AIDS-defining illness, despite highly effective antiretroviral therapy (ART). We (a) assessed the association between incident HIVAW/low weight and all-cause mortality and (b) described virologic outcomes after people with HIV (PWH) experienced HIVAW/low weight while on ART. In the Observational Pharmaco-Epidemiology Research & Analysis (OPERA® ) cohort, PWH without prior HIVAW/low weight who were active in care in 2016-2020 were followed through death, loss to follow-up, or study end (31OCT2021)...
March 14, 2024: AIDS Research and Human Retroviruses
https://read.qxmd.com/read/38478804/csf-%C3%AE-amyloid-and-tau-biomarker-changes-in-veterans-with-mild-traumatic-brain-injury
#23
JOURNAL ARTICLE
Ge Li, Jeffrey Iliff, Jane Shofer, Cynthia L Mayer, James Meabon, David Cook, Kathleen F Pagulayan, Murray A Raskind, Henrik Zetterberg, Kaj Blennow, Elaine R Peskind
BACKGROUND AND OBJECTIVES: Moderate-to-severe traumatic brain injuries (TBI) have been reported to increase the risk of Alzheimer disease (AD). Whether mild TBI (mTBI) in veterans confers a similar increased risk of AD is less known. This study investigated early AD changes using CSF biomarkers in veterans with blast mTBI. METHODS: This was a cross-sectional case-control study of veterans with mTBI and non-mTBI veterans and civilians from 2 study sources. Blast-mTBI veterans had at least 1 war zone blast or combined blast/impact mTBI meeting Veterans Affairs (VA) and Department of Defense (DoD) criteria for mTBI...
April 9, 2024: Neurology
https://read.qxmd.com/read/38478651/assessment-and-quality-improvement-of-the-community-care-network-veterans-administration-va-patient-access-to-community-mohs-micrographic-surgery
#24
JOURNAL ARTICLE
Aheli Chattopadhyay, Drew Saylor, Amanda Twigg
No abstract text is available yet for this article.
October 15, 2023: Dermatology Online Journal
https://read.qxmd.com/read/38477982/posttraumatic-cognition-change-trajectories-in-veterans-with-ptsd-who-completed-an-intensive-cognitive-processing-therapy-treatment-program
#25
JOURNAL ARTICLE
Daniel Szoke, Erin Walker, Nicole Christ, Dale Smith, Philip Held
Negative posttraumatic cognitions (NPCs) have been linked to symptoms of PTSD and are an important target of cognitive behavioral treatments for PTSD, including Cognitive Processing Therapy (CPT). Yet to be explored are the different change trajectories of NPCs during CPT. Knowledge of such change trajectories could elucidate common NPC change processes within CPT and their relationship to PTSD symptom severity. We examined NPC change trajectories in a group of 443 veterans who completed a 2-week intensive CPT program...
March 13, 2024: Cognitive Behaviour Therapy
https://read.qxmd.com/read/38477465/impact-of-human-immunodeficiency-virus-infection-on-liver-and-cardiovascular-outcomes-in-veterans-with-metabolic-dysfunction-associated-steatotic-liver-disease
#26
JOURNAL ARTICLE
Robert J Wong, Zeyuan Yang, Aaron Yeoh, Albert Do, Aijaz Ahmed, Ramsey Cheung
OBJECTIVE: Hepatic steatosis in highly prevalent in people living with human immunodeficiency virus (HIV). It remains unclear whether HIV in patients with metabolic dysfunction associated steatotic liver disease (MASLD) is associated with greater risks of liver disease progression and cardiovascular disease (CVD). We aim to evaluate the impact of HIV infection on risks of liver and CVD outcomes among U.S. Veterans with MASLD. METHODS: Using national Veterans Administration data from 2010-2022, we created a propensity score matched cohort of MASLD patients with vs...
March 13, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38477023/travel-distance-and-outcomes-after-surgical-aortic-valve-among-veterans
#27
JOURNAL ARTICLE
Brendin R Beaulieu-Jones, Noah Siegel, Loreski Collado, Hillary J Mull, Jacquelyn A Quin
OBJECTIVE: To investigate the association between travel distance and postoperative length of stay (LOS) and discharge disposition among veterans undergoing surgical aortic valve replacement (SAVR). DATA SOURCES/STUDY SETTING: We performed a retrospective cohort study of patients undergoing SAVR, with or without coronary artery bypass grafting (CABG) at VA Boston Healthcare (January 1, 2005-December 31, 2015). STUDY DESIGN: Postoperative LOS and discharge disposition were compared for SAVR patients based on travel distance to the facility: <100 miles or ≥100 miles...
March 13, 2024: Health Services Research
https://read.qxmd.com/read/38476245/acorn-sdoh-survey-terminological-representation-for-use-with-nlp-and-cds
#28
JOURNAL ARTICLE
Melissa P Resnick, Diane Montella, Steven H Brown, Peter Elkin
OBJECTIVE: Social Determinants of Health (SDOH) greatly influence health outcomes. SDOH surveys, such as the Assessing Circumstances & Offering Resources for Needs (ACORN) survey, have been developed to screen for SDOH in Veterans. The purpose of this study is to determine the terminological representation of the ACORN survey, to aid in natural language processing (NLP). METHODS: Each ACORN survey question was read to determine its concepts. Next, Solor was searched for each of the concepts and for the appropriate attributes...
2024: Journal of Clinical and Translational Science
https://read.qxmd.com/read/38474127/applying-proteomics-and-computational-approaches-to-identify-novel-targets-in-blast-associated-post-traumatic-epilepsy
#29
JOURNAL ARTICLE
Jack L Browning, Kelsey A Wilson, Oleksii Shandra, Xiaoran Wei, Dzenis Mahmutovic, Biswajit Maharathi, Stefanie Robel, Pamela J VandeVord, Michelle L Olsen
Traumatic brain injury (TBI) can lead to post-traumatic epilepsy (PTE). Blast TBI (bTBI) found in Veterans presents with several complications, including cognitive and behavioral disturbances and PTE; however, the underlying mechanisms that drive the long-term sequelae are not well understood. Using an unbiased proteomics approach in a mouse model of repeated bTBI (rbTBI), this study addresses this gap in the knowledge. After rbTBI, mice were monitored using continuous, uninterrupted video-EEG for up to four months...
March 1, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38472362/risk-factors-of-early-disease-progression-and-decreased-survival-for-multiple-myeloma-patients-after-upfront-autologous-stem-cell-transplantation
#30
JOURNAL ARTICLE
Te-Lin Hsu, Chun-Kuang Tsai, Chun-Yu Liu, Chiu-Mei Yeh, Fen-Lan Lin, Liang-Tsai Hsiao, Yao-Chung Liu, Sheng-Hsuan Chien, Hao-Yuan Wang, Po-Shen Ko, Ting-An Lin, Wen-Chun Chen, Po-Min Chen, Jin-Hwang Liu, Jyh-Pyng Gau, Chia-Jen Liu
Multiple myeloma (MM) stands as the second most prevalent hematological malignancy, constituting approximately 10% of all hematological malignancies. Current guidelines recommend upfront autologous stem cell transplantation (ASCT) for transplant-eligible MM patients. This study seeks to delineate factors influencing post-ASCT outcomes in MM patients. Our cohort comprised 150 MM patients from Taipei Veterans General Hospital, with progression-free survival (PFS) as the primary endpoint and overall survival (OS) as the secondary endpoint...
March 13, 2024: Annals of Hematology
https://read.qxmd.com/read/38469980/examining-associations-between-disordered-eating-and-harmful-substance-use-in-a-nationally-representative-sample-of-us-veterans
#31
JOURNAL ARTICLE
Yiyang Chen, Kara A Christensen Pacella, Kelsie T Forbush, Marianna L Thomeczek, Sonakshi Negi, Alesha E Doan, Alicia M Wendler, R William Morgan, Samiya I Rasheed, Sarah Johnson-Munguia, Anjali R Sharma
OBJECTIVE: The association between eating disorders (EDs) and harmful substance use (substance use that causes psychosocial impairment) is well recognized in the literature, and military veterans may be at heightened risk for both issues due to deployment-related stressors. However, little is known about which ED-related symptoms are associated with harmful substance use in veterans, and whether gender plays a differential role in this relationship. Our aims were to: (1) examine gender differences in ED-related symptoms; and (2) examine whether ED-related symptoms differentially predict harmful substance use in US veteran men and women who had recently separated from service...
March 12, 2024: International Journal of Eating Disorders
https://read.qxmd.com/read/38469833/pain-care-at-home-to-amplify-function-protocol-article
#32
JOURNAL ARTICLE
Anne C Black, Sara N Edmond, Joseph W Frank, Audrey Abelleira, Jennifer L Snow, Danielle M Wesolowicz, William C Becker
Guidelines recommend strategies to optimize opioid medication safety, including frequent reassessment of the benefits and harms of long-term opioid therapy. Prescribers, who are predominantly primary care providers (PCPs), may lack the training or resources to implement these guideline-concordant practices. Two interventions have been designed to assist PCPs and tested within the Veterans Health Administration (VHA). Telemedicine Collaborative Management (TCM) provides primarily medication management support via care manager-prescriber teams...
March 12, 2024: Subst Use Addctn J
https://read.qxmd.com/read/38469244/sleep-disorders-and-cancer-incidence-examining-duration-and-severity-of-diagnosis-among-veterans
#33
JOURNAL ARTICLE
James B Burch, Alexandria F Delage, Hongmei Zhang, Alexander C McLain, Meredith A Ray, Austin Miller, Swann A Adams, James R Hébert
INTRODUCTION: Sleep disruption affects biological processes that facilitate carcinogenesis. This retrospective cohort study used de-identified data from the Veterans Administration (VA) electronic medical record system to test the hypothesis that patients with diagnosed sleep disorders had an increased risk of prostate, breast, colorectal, or other cancers (1999-2010, N=663,869). This study builds upon existing evidence by examining whether patients with more severe or longer-duration diagnoses were at a greater risk of these cancers relative to those with a less severe or shorter duration sleep disorder...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38468997/a-retrospective-comparison-of-onabotulinum-toxin-a-and-incobotulinum-toxin-a-in-terms-of-efficacy-tolerability-duration-of-effect-and-pain-on-injection-administration-site-for-the-treatment-of-chronic-migraine
#34
JOURNAL ARTICLE
Scott Lucchese, Bob Daripa, Shruthi Pulimamidi
Background Onabotulinum toxin A (OnA) is a well-tolerated and effective treatment for chronic migraine (CM). However, based on research indications that incobotulinum toxin A (InA) would be equally effective, a Veterans Health Administration medical center mandated a two-year trial of InA as a more cost-effective alternative to OnA. Although InA is used for many similar indications as OnA, it is not Food and Drug Administration-approved for treating CM, and complications occurred in several patients with CM following this treatment change...
February 2024: Curēus
https://read.qxmd.com/read/38468398/complexity-of-patients-with-mental-healthcare-needs-cared-for-by-mental-health-clinical-pharmacist-practitioners-in-veterans-affairs
#35
JOURNAL ARTICLE
Guneet K Jasuja, Joel I Reisman, Donald R Miller, Elayne D Ansara, Dana L Chiulli, Tera Moore, Heather L Ourth, Michael H Tran, Eric G Smith, Anthony P Morreale, Megan M McCullough
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: The complexity of patients with mental healthcare needs cared for by clinical pharmacists is not well delineated...
March 12, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38468375/child-maltreatment-adult-trauma-and-mental-health-symptoms-among-women-veterans-a-scoping-review-of-published-quantitative-research
#36
REVIEW
Candice Presseau, Jessica R Carney, Nora K Kline, Alyssa A Grimshaw, Lauren DeMoss, Craig Gunderson, Galina A Portnoy
The objective of this scoping review was to describe and synthesize the measures, methods, and key findings of published quantitative research examining the influence of child maltreatment (i.e., abuse and/or neglect) and adult trauma exposure on mental health symptoms among women Veterans. A systematic search from database inception to June 2023 generated 18,861 unique articles retrieved and independently screened for eligibility. A total of 21 articles met pre-established inclusion criteria: (a) quantitative data and results within a sample or subsample of U...
March 11, 2024: Trauma, Violence & Abuse
https://read.qxmd.com/read/38466991/pharmacist-interventions-in-a-palliative-plus-program-at-a-veterans-affairs-medical-center
#37
JOURNAL ARTICLE
Christy Johny Varghese, Amanda Mueller, Lara Schafer, Reika Ebisu, Vinh Dao, Esther Njau
Background: Palliative PLUS (PP) at the Minneapolis Veterans Affairs Health Care System (MVAHCS) is an interdisciplinary team that seeks to improve veteran access to palliative and hospice resources. Palliative care pharmacists were incorporated to increase patient access to palliative specialties. Objective: To identify and categorize pharmacist interventions within an outpatient PP team at the MVAHCS. Methods: This quality improvement project was a retrospective analysis of the electronic health record. Results: A total of 84 patients were participating in the PP program over 13 months...
March 12, 2024: Journal of Palliative Medicine
https://read.qxmd.com/read/38464744/development-and-utility-of-a-clinical-research-informatics-application-for-participant-recruitment-and-workflow-management-for-a-return-of-results-pilot-trial-in-familial-hypercholesterolemia-in-the-million-veteran-program
#38
JOURNAL ARTICLE
Charles A Brunette, Thomas Yi, Morgan E Danowski, Mark Cardellino, Alicia Harrison, Themistocles L Assimes, Joshua W Knowles, Kurt D Christensen, Amy C Sturm, Yan V Sun, Qin Hui, Saiju Pyarajan, Yunling Shi, Stacey B Whitbourne, J Michael Gaziano, Sumitra Muralidhar, Jason L Vassy
OBJECTIVE: The development of clinical research informatics tools and workflow processes associated with re-engaging biobank participants has become necessary as genomic repositories increasingly consider the return of actionable research results. MATERIALS AND METHODS: Here we describe the development and utility of an informatics application for participant recruitment and enrollment management for the Veterans Affairs Million Veteran Program Return Of Actionable Results Study, a randomized controlled pilot trial returning individual genetic results associated with familial hypercholesterolemia...
April 2024: JAMIA Open
https://read.qxmd.com/read/38464073/enhancing-post-traumatic-stress-disorder-patient-assessment-leveraging-natural-language-processing-for-research-of-domain-criteria-identification-using-electronic-medical-records
#39
Oshin Miranda, Sophie Kiehl, Xiguang Qi, Neal David Ryan, Levent Kirisci, M Daniel Brannock, Thomas Kosten, Yanshan Wang, LiRong Wang
Background Extracting research of domain criteria (RDoC) from high-risk populations like those with post-traumatic stress disorder (PTSD) is crucial for positive mental health improvements and policy enhancements. The intricacies of collecting, integrating, and effectively leveraging clinical notes for this purpose introduce complexities. Methods In our study, we created an NLP workflow to analyze electronic medical record (EMR) data, and identify and extract research of domain criteria using a pre-trained transformer-based natural language model, all-mpnet-base-v2...
February 21, 2024: Research Square
https://read.qxmd.com/read/38464044/multiple-informant-cluster-analysis-findings-which-military-connected-preschool-aged-children-are-doing-well-and-why
#40
Patricia Lester, Hilary Aralis, Nastassia Hajal, Brenda Bursch, Norweeta Milburn, Blair Paley, Maegan Sinclair Cortez, Wendy Barrera, Cara Kiff, William Beardslee, Catherine Mogil
Informed by models of resilience in military families, we explored factors theorized to be associated with social-emotional resilience and risk among young military-connected children. Our secondary analysis of cross-sectional data from 199 military-connected families (n = 346 parents) with at least one preschool-age child in the home (n = 199) led to the empirical identification of two distinct clusters: families with children demonstrating healthy social-emotional functioning and those showing indicators of poor social-emotional functioning...
February 27, 2024: Research Square
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