Shelesh Krishna Saraswat, Bashar Shaker Mahmood, Freddy Ajila, Doaa Saadi Kareem, Mariem Alwan, Zainab H Athab, Jalal Brism Shaier, Seyed Reza Hosseinifard
The in-depth exploration of long non-coding RNAs (lncRNAs) reveals their pivotal and diverse roles in various disorders, particularly cancer. Within this intricate landscape, thymopoietin-antisense RNA-1 (TMPO-AS1) emerges as a noteworthy instigator of oncogenesis in humans. This exhaustive review seeks to intricately unravel the present understanding of TMPO-AS1, emphasizing its molecular foundations and highlighting its clinical applications in the realm of cancer research. TMPO-AS1 consistently exhibits heightened expression across a spectrum of cancer types, encompassing lung, colorectal, breast, cervical, bladder, pancreatic, hepatocellular, gastric, ovarian, and osteosarcoma...
February 2, 2024: Pathology, Research and Practice