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https://www.readbyqxmd.com/read/28211758/life-cycle-host-utilization-and-ecological-fitting-for-invasive-lancet-liver-fluke-dicrocoelium-dendriticum-emerging-in-southern-alberta-canada
#1
Bradley van Paridon, John S Gilleard, Douglas D Colwell, Cameron P Goater
The expansion of parasite distributions outside of their native host and geographical ranges has occurred repeatedly over evolutionary time. Contemporary examples include emerging infectious diseases (EID's), many of which pose threats to human, domestic animal, and wildlife populations. Theory predicts that parasites with complex life cycles will be rare as EID's due to constraints imposed by host specialization at each life-cycle stage. In contrast to predictions of this theory, we report 2 new intermediate hosts in the 3-host life cycle of the liver fluke Dicrocoelium dendriticum in Cypress Hills Provincial Park, Alberta, Canada...
February 17, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28197787/dermatux-phase-iv-trial-of-cetuximab-plus-folfiri-in-first-line-metastatic-colorectal-cancer-receiving-a-pre-defined-skin-care
#2
Carl Christoph Schimanski, Frank Staib, Thomas Göhler, Holger Hebart, Michael Heike, Michael Neise, Jochen Rudi, Thomas Geer, Gerrit Dingeldein, Claudia Lang, Peter Ehscheidt, Thomas Flohr, Klaus Maria Josten, Meinolf Karthaus, Alexander Schmittel, Jan Wierecky, Emil Boller, Martin Indorf, Marcus-Alexander Wörns, Peter R Galle, Markus Moehler
PURPOSE: Cetuximab-induced skin rash Gd3+ occurs in ≥16% patients (pts) (Heinemann et al., Lancet Oncol 15(10):1065-1075, 2014; Van Cutsem et al. J Clin Oncol 27(19):3117-25; 2009b). Survival, response, and toxicity parameters were re-evaluated under a pre-defined skin prophylaxis consistent of vitamin K1 ointment and oral doxycycline. METHODS: This is a national, multicenter, phase 4, first-line mCRC (K-RAS wt) trial. Pts received irinotecan 180 mg/m² (d1), FA 400 mg/m² (d1), 5-FU 400 mg/m² (d1), 5-FU 2400 mg/m² (d1-2), and cetuximab [400 mg/m² (d1), and then 250 mg/m² qw], prophylactic 0...
February 14, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28195042/germany-s-science-strategy-is-proudly-international
#3
EDITORIAL
The Lancet
No abstract text is available yet for this article.
February 11, 2017: Lancet
https://www.readbyqxmd.com/read/28195041/complexities-of-care-in-copd
#4
EDITORIAL
The Lancet
No abstract text is available yet for this article.
February 11, 2017: Lancet
https://www.readbyqxmd.com/read/28195040/another-kind-of-zika-public-health-emergency
#5
EDITORIAL
The Lancet
No abstract text is available yet for this article.
February 11, 2017: Lancet
https://www.readbyqxmd.com/read/28193396/correction-to-lancet-glob-health-2013-4-e642-53
#6
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28193379/surprise-us-mr-trump
#7
EDITORIAL
The Lancet Global Health
No abstract text is available yet for this article.
March 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28185975/effect-of-geopolitical-forces-on-neurosurgical-training-in-sub-saharan-africa
#8
Kara E Dempsey, Mahmood M Qureshi, Solomon M Ondoma, Robert J Dempsey
BACKGROUND: The population of Sub-Saharan Africa suffers from a critical shortage and maldistribution of healthcare professionals, especially highlighted in surgical subspecialties such as neurosurgery. In light of the Lancet Report and the World Health Organization's directive to provide essential surgical care through the developing world, solutions need to be found to close this training and distribution gap. METHODS: Methods correcting the situation will only succeed if one understands the geopolitical forces which have shaped the distribution of healthcare in the region and continue to this day...
February 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28185797/evidence-for-selective-benefit-of-sequential-treatment-with-hypomethylating-agents-in-patients-with-myelodysplastic-syndrome
#9
Susmitha Apuri, Najla Al Ali, Eric Padron, Jeffrey E Lancet, Alan F List, Rami S Komrokji
BACKGROUND: Hypomethylating agents (HMAs) remain the mainstay of treatment of patients with myelodysplastic syndrome (MDS). Azacitidine is the only agent shown to improve overall survival in higher risk MDS. The sequential use of HMAs is common practice, given the limited alternatives. The response rate to azacitidine after decitabine is unknown. To investigate the potential benefit of this approach, we reviewed all cases of sequential HMA treatment. PATIENTS AND METHODS: The Moffitt Cancer Center MDS database was reviewed, and 2 groups were identified...
January 10, 2017: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/28178764/borderline-ovarian-tumours-balancing-risks-of-recurrence-over-decades
#10
Joanne Morrison
Borderline ovarian tumours account for 10-15% of epithelial tumours. Women are on average 10 years younger than those invasive ovarian epithelial tumours (Morice et al. Lancet Oncol 2012; 13: 103-115) and many will have fertility as a major concern. Many women are unexpectedly diagnosed after conservative surgery, following either cystectomy or unilateral oophorectomy. Frozen section can be useful for informing intra-operative management (Ratnavelu et al. Cochrane Database of Syst Rev 2016; (3): CD010360), informing a conservative surgical approach of a suspicious mass...
February 8, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28178762/pet-trumps-surgical-staging-in-locally-advanced-cervical-cancer
#11
Leigh A Cantrell, Linda R Duska
Locally advanced cervical cancer (LACC) is a significant problem. The status of the para-aortic lymph nodes (PALN) in women with LACC is critical, as positive PALN dictate extended radiation fields and portend a dismal prognosis. Since 10-25% of women with LACC will have PALN metastases (S Gout, et al. Lancet Oncol 13(5) 2012), the ideal method to identify and treat them is paramount. This article is protected by copyright. All rights reserved.
February 8, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28178120/the-top-cited-systematic-reviews-meta-analyses-in-tuberculosis-research-a-prisma-compliant-systematic-literature-review-and-bibliometric-analysis
#12
Yonggang Zhang, Jin Huang, Liang Du
BACKGROUND: The top-cited systematic reviews/meta-analyses in tuberculosis research have not been identified. The objective of this study was to identify the 100 top-cited systematic reviews/meta-analyses in tuberculosis research, and to understand factors resulting in highly cited works, and establish trends in systematic reviews/meta-analyses in tuberculosis research. METHODS: The Web of Science Core Collection was searched for systematic reviews/meta-analyses on tuberculosis up to January 31, 2016...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28170320/free-speech-and-facts-in-the-trump-era
#13
EDITORIAL
The Lancet
No abstract text is available yet for this article.
February 4, 2017: Lancet
https://www.readbyqxmd.com/read/28170319/health-in-slums-understanding-the-unseen
#14
EDITORIAL
The Lancet
No abstract text is available yet for this article.
February 4, 2017: Lancet
https://www.readbyqxmd.com/read/28170318/the-health-inequalities-and-ill-health-of-children-in-the-uk
#15
EDITORIAL
The Lancet
No abstract text is available yet for this article.
February 4, 2017: Lancet
https://www.readbyqxmd.com/read/28163021/calling-the-shots
#16
EDITORIAL
The Lancet Respiratory Medicine
No abstract text is available yet for this article.
February 2, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28159734/monocyte-subset-analysis-accurately-distinguishes-cmml-from-mds-and-is-associated-with-a-favorable-mds-prognosis
#17
Chetasi Talati, Ling Zhang, Ghada Shaheen, Andrew Kuykendall, Markus Ball, Qing Zhang, Jeffrey E Lancet, Kenneth S Zuckerman, Alan F List, Rami Komrokji, Lynn Moscinski, Eric Padron
No abstract text is available yet for this article.
February 3, 2017: Blood
https://www.readbyqxmd.com/read/28159549/the-xxxx-files-mq-swears-in
#18
EDITORIAL
The Lancet Psychiatry
No abstract text is available yet for this article.
January 31, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28159187/look-up-in-the-sky-it-s-a-bird-it-s-a-plane-it-s-a-medical-drone
#19
EDITORIAL
The Lancet Haematology
No abstract text is available yet for this article.
February 2017: Lancet Haematology
https://www.readbyqxmd.com/read/28153383/non-hodgkin-lymphoma
#20
REVIEW
James O Armitage, Randy D Gascoyne, Matthew A Lunning, Franco Cavalli
Lymphomas can affect any organ in the body, present with a wide range of symptoms, and be seen by primary care physicians and physicians from most specialties. They are traditionally divided into Hodgkin's lymphoma (which accounts for about 10% of all lymphomas) and non-Hodgkin lymphoma, which is the topic of this Seminar. Non-Hodgkin lymphoma represents a wide spectrum of illnesses that vary from the most indolent to the most aggressive malignancies. They arise from lymphocytes that are at various stages of development, and the characteristics of the specific lymphoma subtype reflect those of the cell from which they originated...
January 30, 2017: Lancet
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