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https://www.readbyqxmd.com/read/27264216/impact-of-an-atrial-fibrillation-decision-support-tool-on-thromboprophylaxis-for-atrial-fibrillation
#1
Mark H Eckman, Gregory Y H Lip, Ruth E Wise, Barbara Speer, Megan Sullivan, Nita Walker, Brett Kissela, Matthew L Flaherty, Dawn Kleindorfer, Peter Baker, Robert Ireton, Dave Hoskins, Brett M Harnett, Carlos Aguilar, Anthony C Leonard, Lora Arduser, Dylan Steen, Alexandru Costea, John Kues
BACKGROUND: Appropriate thromboprophylaxis for patients with atrial fibrillation (AF) remains a national challenge. METHODS: We hypothesized that provision of decision support in the form of an Atrial Fibrillation Decision Support Tool (AFDST) would improve thromboprophylaxis for AF patients. We conducted a cluster randomized trial involving 15 primary care practices and 1,493 adults with nonvalvular AF in an integrated health care system between April 2014 and February 2015...
June 2016: American Heart Journal
https://www.readbyqxmd.com/read/26629008/transcatheter-closure-of-the-left-atrial-appendage-initial-experience-with-the-watchman-device
#2
Jiandong Ding, Jian Zhu, Jing Lu, Xiuxia Ding, Xiaoli Zhang, Wenbin Lu, Mingqiang Ao, Genshan Ma
BACKGROUND: Atrial fibrillation (AF) is the most commonly encountered clinical arrhythmia, accounting for approximately one third of hospitalizations for cardiac rhythm disturbance. In patients with non-valvular AF, approximately 90% of thrombi are thought to arise from the left atrial appendage (LAA). Anticoagulation with warfarin has been the mainstay of therapy to reduce stroke risk in these patients; however, it is not without its complications including bleeding and drug interactions...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/26183170/demographic-and-clinical-characteristics-to-predict-paroxysmal-atrial-fibrillation-insights-from-an-implantable-loop-recorder-population
#3
Antonio Frontera, Alexander Carpenter, Nauman Ahmed, Matteo Fasiolo, Martin Nelson, Ihab Diab, Tim Cripps, Glyn Thomas, Edward Duncan
BACKGROUND: There is growing interest in detecting paroxysmal atrial fibrillation (PAF) to identify patients at high risk of thromboembolic stroke. The implantable loop recorder (ILR) is emerging as a powerful new tool in the diagnosis of PAF. Widespread implantation has significant cost implications and their use must be targeted at those patients at most risk. METHODS: We retrospectively studied a population of 200 adult patients who underwent ILR implantation for the investigation of syncope or palpitations...
October 2015: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/26001109/the-italian-start-register-on-anticoagulation-with-focus-on-atrial-fibrillation
#4
MULTICENTER STUDY
Emilia Antonucci, Daniela Poli, Alberto Tosetto, Vittorio Pengo, Armando Tripodi, Nicola Magrini, Francesco Marongiu, Gualtiero Palareti
START-Register--Survey on anTicoagulated pAtients RegisTer--is an independent, inception-cohort, observational, collaborative database aimed at recording prospectively the clinical history of adult patients starting anticoagulant treatment for any reason and using whatever drug. In this article we present the START-Register and give cross section baseline data focusing on non valvular atrial fibrillation (NVAF). Participants are asked to insert prospectively consecutive patients recorded as electronic file on the web-site of the registry...
2015: PloS One
https://www.readbyqxmd.com/read/25815182/advanced-chronic-kidney-disease-in-non-valvular-atrial-fibrillation-extending-the-utility-of-r2chads2-to-patients-with-advanced-renal-failure
#5
Josef Bautista, Archie Bella, Ashok Chaudhari, Gerald Pekler, Katherine J Sapra, Roger Carbajal, Donald Baumstein
BACKGROUND: The R2CHADS2 is a new prediction rule for stroke risk in atrial fibrillation (AF) patients wherein R stands for renal risk. However, it was created from a cohort that excluded patients with advanced renal failure (defined as glomerular filtration rate of <30 mL/min). Our study extends the use of R2CHADS2 to patients with advanced renal failure and aims to compare its predictive power against the currently used CHADS and CHA2DS2VaSc. METHODS: This retrospective cohort study analyzed the 1-year risk for stroke of the 524 patients with AF at Metropolitan Hospital Center...
April 2015: Clinical Kidney Journal
https://www.readbyqxmd.com/read/25352505/atrial-fibrillation-in-decompensated-heart-failure-associated-factors-and-in-hospital-outcome
#6
Fernanda de Souza Nogueira Sardinha Mendes, Jacob Atié, Marcelo Iorio Garcia, Eliza de Almeida Gripp, Andréa Silvestre de Sousa, Luiz Augusto Feijó, Sergio Salles Xavier
BACKGROUND: Studies on atrial fibrillation (AF) in decompensated heart failure (DHF) are scarce in Brazil. OBJECTIVES: To determine AF prevalence, its types and associated factors in patients hospitalized due to DHF; to assess their thromboembolic risk profile and anticoagulation rate; and to assess the impact of AF on in-hospital mortality and hospital length of stay. METHODS: Retrospective, observational, cross-sectional study of incident cases including 659 consecutive hospitalizations due to DHF, from 01/01/2006 to 12/31/2011...
October 2014: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/25211202/atrial-fibrillation-in-decompensated-heart-failure-associated-factors-and-in-hospital-outcome
#7
Fernanda de Souza Nogueira Sardinha Mendes, Jacob Atié, Marcelo Iorio Garcia, Eliza de Almeida Gripp, Andréa Silvestre de Sousa, Luiz Augusto Feijó, Sergio Salles Xavier
Background: Studies on atrial fibrillation (AF) in decompensated heart failure (DHF) are scarce in Brazil. Objectives: To determine AF prevalence, its types and associated factors in patients hospitalized due to DHF; to assess their thromboembolic risk profile and anticoagulation rate; and to assess the impact of AF on in-hospital mortality and hospital length of stay. Methods: Retrospective, observational, cross-sectional study of incident cases including 659 consecutive hospitalizations due to DHF, from 01/01/2006 to 12/31/2011...
August 29, 2014: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/25156854/conventional-radiofrequency-catheter-ablation-compared-to-multi-electrode-ablation-for-atrial-fibrillation
#8
RANDOMIZED CONTROLLED TRIAL
Pim Gal, Alissa E S M Aarntzen, Jaap Jan J Smit, Ahmet Adiyaman, Anand R Ramdat Misier, Peter Paul H M Delnoy, Arif Elvan
BACKGROUND: Limited data is available on long-term atrial fibrillation (AF) free survival after multi-electrode catheter pulmonary vein isolation (PVI). The aim of this study was to compare point-by-point PVI to multi-electrode PVI in terms of procedural characteristics and long-term AF free survival. METHODS AND RESULTS: 460 consecutive patients were randomly allocated: 230 patients underwent conventional, point-by-point ablation with a radiofrequency ablation catheter (cPVI group) and 230 patients underwent multi-electrode, phased radiofrequency ablation (MER group)...
October 20, 2014: International Journal of Cardiology
https://www.readbyqxmd.com/read/25088125/atrial-fibrillation-new-frontiers-in-anticoagulation
#9
REVIEW
Ranji Thomas, Pierre Le Page, Andrew R J Mitchell
Stroke is the most feared complication of atrial fibrillation but for over fifty years there has been no simple, effective preventative alternative to warfarin. The development of new risk algorithms such as CHADSVASC has resulted in more patients being recommended anticoagulation therapy. Fixed dose oral anticoagulation is a landmark in drug development for atrial fibrillation. The differences between the drugs are discussed and the trial data examined. As we enter this new frontier of therapy, there is no doubt that these drugs will transform the delivery of anticoagulation for patients with atrial fibrillation...
2014: Cardiovascular & Hematological Disorders Drug Targets
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